DE602004005033D1 - Benzamidinhibitoren des p2x7-rezeptors - Google Patents
Benzamidinhibitoren des p2x7-rezeptorsInfo
- Publication number
- DE602004005033D1 DE602004005033D1 DE602004005033T DE602004005033T DE602004005033D1 DE 602004005033 D1 DE602004005033 D1 DE 602004005033D1 DE 602004005033 T DE602004005033 T DE 602004005033T DE 602004005033 T DE602004005033 T DE 602004005033T DE 602004005033 D1 DE602004005033 D1 DE 602004005033D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor
- benzamidinhibitors
- disorders
- copd
- reperfusion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47000103P | 2003-05-12 | 2003-05-12 | |
| US470001P | 2003-05-12 | ||
| PCT/IB2004/001525 WO2004099146A1 (en) | 2003-05-12 | 2004-05-10 | Benzamide inhibitors of the p2x7 receptor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004005033D1 true DE602004005033D1 (de) | 2007-04-12 |
| DE602004005033T2 DE602004005033T2 (de) | 2007-08-09 |
Family
ID=33435257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004005033T Active DE602004005033T2 (de) | 2003-05-12 | 2004-05-10 | Benzamidinhibitoren des p2x7-rezeptors |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7186742B2 (de) |
| EP (1) | EP1626962B1 (de) |
| JP (1) | JP4731468B2 (de) |
| AT (1) | ATE355273T1 (de) |
| BR (1) | BRPI0410349A (de) |
| CA (1) | CA2525437C (de) |
| DE (1) | DE602004005033T2 (de) |
| ES (2) | ES2396565T3 (de) |
| MX (1) | MXPA05012086A (de) |
| WO (1) | WO2004099146A1 (de) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PA8557501A1 (es) * | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
| US7071223B1 (en) | 2002-12-31 | 2006-07-04 | Pfizer, Inc. | Benzamide inhibitors of the P2X7 receptor |
| PA8591801A1 (es) * | 2002-12-31 | 2004-07-26 | Pfizer Prod Inc | Inhibidores benzamidicos del receptor p2x7. |
| ES2396565T3 (es) | 2003-05-12 | 2013-02-22 | Pah Usa 15 Llc | Inhibidores benzamida del receptor P2X7 |
| AU2005258911A1 (en) * | 2004-06-29 | 2006-01-12 | Pfizer Products Inc. | Method for preparing 5-`4-(2-hydroxy-propyl)-3,5-dioxo-4,5-dihydro-3H`1,2,4!triazin-2-YL!-benzamide derivatives by deprotecting the hydroxyl-protected precursers |
| MXPA06014023A (es) * | 2004-06-29 | 2007-02-08 | Warner Lambert Co | Terapias combinadas que utilizan inhibidores de benzamida del receptor p2x7. |
| US7592459B2 (en) * | 2004-09-29 | 2009-09-22 | Chemagis Ltd. | Use of purified donepezil maleate for preparing pharmaceutically pure amorphous donepezil hydrochloride |
| WO2006080884A1 (en) * | 2005-01-27 | 2006-08-03 | Astrazeneca Ab | Novel biaromatic compounds, inhibitors of the p2x7-receptor |
| EP1963275A2 (de) * | 2005-11-09 | 2008-09-03 | Abbott Laboratories | P2x7-rezeptorantagonisten und anwendungen davon |
| US8501933B2 (en) | 2006-11-09 | 2013-08-06 | Roche Palo Alto Llc | Thiazole and oxazole-substituted arylamides as P2X3 and P2X2/3 antagonists |
| BRPI0718714B8 (pt) * | 2006-11-09 | 2021-05-25 | Hoffmann La Roche | arilamidas substituídas por tiazol e oxazol, seu uso e composição farmacêutica que as compreende |
| ES2576643T3 (es) * | 2007-03-09 | 2016-07-08 | Second Genome, Inc. | Compuestos de bicicloheteroarilo como moduladores de P2X7 y usos de los mismos |
| BRPI0809106A2 (pt) * | 2007-03-22 | 2014-08-26 | Astrazeneca Ab | Derivados de quinolina para o tratamento de doenças inflamatórias |
| MY154668A (en) * | 2007-07-19 | 2015-07-15 | Lundbeck & Co As H | 5-membered heterocyclic amides and related compounds |
| RU2010121763A (ru) * | 2007-10-31 | 2011-12-10 | Ниссан Кемикал Индастриз, Лтд. (Jp) | Производные пиридазинона и ингибиторы р2х7 рецептора |
| ES2517518T3 (es) * | 2007-12-17 | 2014-11-03 | F. Hoffmann-La Roche Ag | Derivados arilamida sustituidos con tetrazol y su utilización como antagonistas de receptores purinérgicos P2X3 y/o P2X2/3 |
| BR122018070508B8 (pt) | 2007-12-17 | 2021-07-27 | Hoffmann La Roche | derivados de arilamida triazol-substituída e seu uso |
| JP5318882B2 (ja) * | 2007-12-17 | 2013-10-16 | エフ．ホフマン−ラ ロシュ アーゲー | 新規なイミダゾール置換アリールアミド |
| CA2707988C (en) * | 2007-12-17 | 2016-08-30 | F. Hoffmann-La Roche Ag | Novel pyrazole-substituted arylamides |
| NZ587799A (en) | 2008-03-25 | 2012-06-29 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
| BRPI0922645A2 (pt) * | 2008-12-16 | 2019-09-24 | Hoffmann La Roche | "arilamidas tiadiazol substituídas". |
| PL2243772T3 (pl) | 2009-04-14 | 2012-05-31 | Affectis Pharmaceuticals Ag | Nowi antagoniści p2x7r i ich zastosowanie |
| CN102438989B (zh) | 2009-06-22 | 2015-05-27 | 霍夫曼-拉罗奇有限公司 | 噁唑酮和吡咯烷酮取代的芳基酰胺 |
| EP2445868B1 (de) * | 2009-06-22 | 2013-12-18 | F.Hoffmann-La Roche Ag | Biphenylamide verwenbar als p2x3- und/oder p2x2/3-rezeptoren modulatoren |
| CN102803245B (zh) | 2009-06-22 | 2015-02-11 | 弗·哈夫曼-拉罗切有限公司 | 作为p2x3和/或p2x2/3拮抗剂的吲哚、吲唑和苯并咪唑芳基酰胺类 |
| EA201290876A1 (ru) | 2010-03-05 | 2013-03-29 | Президент Энд Феллоуз Оф Гарвард Колледж | Композиции индуцированных дендритных клеток и их использование |
| JP2013526496A (ja) | 2010-05-14 | 2013-06-24 | アフェクティス ファーマシューティカルズ アーゲー | Ｐ２ｘ７ｒ拮抗剤の新規調製方法 |
| WO2012110190A1 (en) | 2011-02-17 | 2012-08-23 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
| EP2678317A1 (de) | 2011-02-22 | 2014-01-01 | Actelion Pharmaceuticals Ltd. | Benzamidderivate als p2x7-rezeptorantagonisten |
| US9464065B2 (en) | 2011-03-24 | 2016-10-11 | The Scripps Research Institute | Compounds and methods for inducing chondrogenesis |
| WO2012163792A1 (en) | 2011-05-27 | 2012-12-06 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
| WO2012163456A1 (en) | 2011-05-27 | 2012-12-06 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
| BR112014001454A2 (pt) | 2011-07-22 | 2017-06-27 | Actelion Pharmaceuticals Ltd | derivados de amidas heterocíclicas como antagonistas do receptor de p2x7 |
| CN102993096A (zh) * | 2011-09-13 | 2013-03-27 | 宁波大学 | 一种n-吡唑酰胺衍生物及其制备方法 |
| KR102033190B1 (ko) | 2012-01-20 | 2019-10-16 | 이도르시아 파마슈티컬스 리미티드 | Ｐ２ｘ７ 수용체 길항제로서의 헤테로시클릭 아미드 유도체 |
| CA2884848C (en) | 2012-09-28 | 2017-08-22 | Pfizer Inc. | Benzamide and heterobenzamide compounds |
| TW201427947A (zh) | 2012-10-12 | 2014-07-16 | Lundbeck & Co As H | 環狀胺 |
| TWI598325B (zh) * | 2012-10-12 | 2017-09-11 | Ｈ 朗德貝克公司 | 苯甲醯胺類 |
| TWI612034B (zh) | 2012-12-12 | 2018-01-21 | 愛杜西亞製藥有限公司 | 作爲ｐ２ｘ７受體拮抗劑之吲哚羧醯胺衍生物 |
| EP2935211B1 (de) | 2012-12-18 | 2016-11-09 | Actelion Pharmaceuticals Ltd. | Indolcarboxamidderivate als p2x7-rezeptorantagonisten |
| CA2897459C (en) | 2013-01-22 | 2021-03-02 | Actelion Pharmaceuticals Ltd | Heterocyclic amide derivatives as p2x7 receptor antagonists |
| KR102222220B1 (ko) | 2013-01-22 | 2021-03-03 | 이도르시아 파마슈티컬스 리미티드 | Ｐ2ｘ7 수용체 길항제로서의 헤테로시클릭 아미드 유도체 |
| EP2968330B1 (de) | 2013-03-15 | 2021-09-29 | The Scripps Research Institute | Verbindungen und verfahren zur induktion von chondrogenese |
| JP6422164B2 (ja) | 2013-12-26 | 2018-11-14 | 塩野義製薬株式会社 | 含窒素６員環誘導体およびそれらを含有する医薬組成物 |
| EP2905282A1 (de) * | 2014-02-05 | 2015-08-12 | AXXAM S.p.A. | Substituierte Thiazole oder Oxazole als P2X7-Rezeptorantagonisten |
| JP6358639B2 (ja) | 2015-04-24 | 2018-07-18 | 塩野義製薬株式会社 | ６員複素環誘導体およびそれらを含有する医薬組成物 |
| WO2017108569A1 (en) | 2015-12-22 | 2017-06-29 | Syngenta Participations Ag | Pesticidally active pyrazole derivatives |
| EP3290417A1 (de) | 2016-08-31 | 2018-03-07 | AXXAM S.p.A. | 2-chloro-n-[2-(1,3-thiazol-5-yl)ethyl]-5-(5-fluoropyrimidin-2-yl)-benzamide und ihre verwendung als p2x7 rezeptor antagonisten |
| EP3290416A1 (de) | 2016-08-31 | 2018-03-07 | AXXAM S.p.A. | Substituierte n-[2-(4-phenoxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamid- und n-[2-(4-benzyloxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamid- derivate und ihre verwendung als p2x7 rezeptor antagonist |
| EP3527568A4 (de) | 2016-10-17 | 2020-03-18 | Shionogi & Co., Ltd | Bicyclisches nitrogeniertes heterocyclisches derivat und pharmazeutische zusammensetzung damit |
| EP3398941A1 (de) | 2017-05-03 | 2018-11-07 | AXXAM S.p.A. | Heterozyklische p2x7-antagonisten |
| CA3121202A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| AU2021209962A1 (en) * | 2020-01-24 | 2022-09-15 | Kayothera Inc. | Heterocyclic compounds and uses thereof |
| EP4015039A1 (de) | 2020-12-18 | 2022-06-22 | AXXAM S.p.A. | Heterocyclische derivate als p2x7-rezeptor-antagonisten |
| CN117881675A (zh) | 2021-09-03 | 2024-04-12 | 布雷耶疗法有限公司 | 2,4-二氢-3h-1,2,4-三唑-3-酮p2x7拮抗剂 |
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| US5672715A (en) * | 1995-06-07 | 1997-09-30 | Monsanto Company | Herbicidal substituted 3-aryl-pyrazoles |
| JP3906935B2 (ja) * | 1995-12-18 | 2007-04-18 | 杏林製薬株式会社 | Ｎ−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
| US5939418A (en) * | 1995-12-21 | 1999-08-17 | The Dupont Merck Pharmaceutical Company | Isoxazoline, isothiazoline and pyrazoline factor Xa inhibitors |
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-
2004
- 2004-05-10 ES ES07103182T patent/ES2396565T3/es active Active
- 2004-05-10 CA CA002525437A patent/CA2525437C/en not_active Expired - Fee Related
- 2004-05-10 AT AT04731975T patent/ATE355273T1/de not_active IP Right Cessation
- 2004-05-10 BR BRPI0410349-1A patent/BRPI0410349A/pt not_active IP Right Cessation
- 2004-05-10 MX MXPA05012086A patent/MXPA05012086A/es unknown
- 2004-05-10 ES ES04731975T patent/ES2281801T3/es active Active
- 2004-05-10 JP JP2006506618A patent/JP4731468B2/ja not_active Expired - Fee Related
- 2004-05-10 WO PCT/IB2004/001525 patent/WO2004099146A1/en active IP Right Grant
- 2004-05-10 DE DE602004005033T patent/DE602004005033T2/de active Active
- 2004-05-10 EP EP04731975A patent/EP1626962B1/de not_active Not-in-force
- 2004-05-12 US US10/844,251 patent/US7186742B2/en not_active Expired - Fee Related
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2007
- 2007-02-09 US US11/673,246 patent/US7553972B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7186742B2 (en) | 2007-03-06 |
| MXPA05012086A (es) | 2006-02-22 |
| DE602004005033T2 (de) | 2007-08-09 |
| EP1626962B1 (de) | 2007-02-28 |
| BRPI0410349A (pt) | 2006-05-30 |
| US7553972B2 (en) | 2009-06-30 |
| JP2006525991A (ja) | 2006-11-16 |
| ATE355273T1 (de) | 2006-03-15 |
| US20070142329A1 (en) | 2007-06-21 |
| ES2281801T3 (es) | 2007-10-01 |
| WO2004099146A1 (en) | 2004-11-18 |
| US20050009900A1 (en) | 2005-01-13 |
| CA2525437A1 (en) | 2004-11-18 |
| ES2396565T3 (es) | 2013-02-22 |
| JP4731468B2 (ja) | 2011-07-27 |
| CA2525437C (en) | 2009-04-28 |
| EP1626962A1 (de) | 2006-02-22 |
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