DE602004012314D1 - Niedermolekulare polysaccharide mit antithrombotischer wirkung - Google Patents
Niedermolekulare polysaccharide mit antithrombotischer wirkungInfo
- Publication number
- DE602004012314D1 DE602004012314D1 DE602004012314T DE602004012314T DE602004012314D1 DE 602004012314 D1 DE602004012314 D1 DE 602004012314D1 DE 602004012314 T DE602004012314 T DE 602004012314T DE 602004012314 T DE602004012314 T DE 602004012314T DE 602004012314 D1 DE602004012314 D1 DE 602004012314D1
- Authority
- DE
- Germany
- Prior art keywords
- sulfate
- epik5
- lmw
- depolymerized
- sulfation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT002498A ITMI20032498A1 (it) | 2003-12-17 | 2003-12-17 | Polisaccaridi antitrombotici a basso peso molecolare e |
ITMI20030249 | 2003-12-17 | ||
PCT/IB2004/004128 WO2005058976A2 (en) | 2003-12-17 | 2004-12-15 | Low molecular polysaccharides having antithrombotic activity |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602004012314D1 true DE602004012314D1 (de) | 2008-04-17 |
DE602004012314T2 DE602004012314T2 (de) | 2009-03-19 |
Family
ID=34685622
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004012314T Active DE602004012314T2 (de) | 2003-12-17 | 2004-12-15 | Niedermolekulare polysaccharide mit antithrombotischer wirkung |
Country Status (9)
Country | Link |
---|---|
US (1) | US7812151B2 (de) |
EP (1) | EP1694714B8 (de) |
JP (1) | JP4975443B2 (de) |
AT (1) | ATE388169T1 (de) |
DE (1) | DE602004012314T2 (de) |
ES (1) | ES2302065T3 (de) |
IT (1) | ITMI20032498A1 (de) |
PT (1) | PT1694714E (de) |
WO (1) | WO2005058976A2 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20032498A1 (it) | 2003-12-17 | 2005-06-18 | Pasqua Anna Oreste | Polisaccaridi antitrombotici a basso peso molecolare e |
ITMI20010397A1 (it) * | 2001-02-27 | 2002-08-27 | Giorgio Zoppetti | Derivati altamente n,o-solfatati del polisaccaride k5 e loro preparazione |
US8513407B2 (en) * | 2002-06-18 | 2013-08-20 | Glycores 2000 S.R.L. | Process for the preparation of N-acyl-(epi)K5-amine-O-sulfate-derivatives and products thus obtained |
US20120253029A1 (en) | 2002-06-18 | 2012-10-04 | Pasqua Anna Oreste | Process for the preparation of highly o-sulfated epimerized derivatives of k5 polysaccharide and intermediates therein |
MXPA04012805A (es) * | 2002-06-18 | 2005-08-19 | Glycores 2000 Srl | Polisacarido sulfatado en exceso de bajo peso molecular. |
EP1872791A1 (de) * | 2006-06-30 | 2008-01-02 | Institut Pasteur | Verwendung von Polysacchariden bakteriellen Ursprungs zur Hemmung der Bildung von Biofilmen |
JP7006275B2 (ja) * | 2015-12-28 | 2022-02-10 | 味の素株式会社 | グルコサミン残基の3-o-硫酸化率が高いヘパラン硫酸 |
CN110776578B (zh) * | 2019-11-12 | 2021-01-29 | 苏州颐华生物医药技术股份有限公司 | 低分子海参糖胺聚糖及其应用 |
CN111875714B (zh) * | 2020-08-05 | 2022-05-20 | 青岛海洋生物医药研究院股份有限公司 | 低分子量硫酸半乳聚糖及其制备方法和应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1141483B (it) | 1980-04-18 | 1986-10-01 | Crinos Industria Farmaco | Resina poliamminica per la separazione selettiva di eparina da altri glucosamminoglicani e procedimento per la sua preparazione |
DE3787996T2 (de) | 1986-05-16 | 1994-03-03 | Italfarmaco Spa | Heparine, frei von E.D.T.A., Fraktionen und Fragmente von Heparin, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, welche diese enthalten. |
FR2684385B1 (fr) * | 1991-11-28 | 1997-08-01 | Sanofi Elf | Heparosanes-n,o-sulfates de haute masse moleculaire, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
IT1271057B (it) | 1994-11-04 | 1997-05-26 | Inalco Spa | Polisaccaridi aventi un elevato contenuto di acido iduronico |
IT1282994B1 (it) * | 1996-05-10 | 1998-04-03 | Inalco Spa | Derivati del polisaccaride k5 aventi elevata attivita' anticoagulante |
IT1289613B1 (it) | 1997-02-07 | 1998-10-15 | Inalco Spa | Polisaccaridi batterici o-solfatati |
US20020062019A1 (en) | 2000-03-30 | 2002-05-23 | Pasqua Oreste | Glycosaminoglycans derived from K5 polysaccharide having high anticoagulant and antithrombotic activities and process for their preparation |
IT1318432B1 (it) | 2000-03-30 | 2003-08-25 | Inalco Spa | Glicosaminoglicani derivati dal polisaccaride k5 aventi elevataattivita' anticoagulante ed antitrombotica e processo per la loro |
ITMI20032498A1 (it) | 2003-12-17 | 2005-06-18 | Pasqua Anna Oreste | Polisaccaridi antitrombotici a basso peso molecolare e |
US20050027117A1 (en) | 2000-12-18 | 2005-02-03 | Pasqua Oreste | Anticoagulant and antithrombotic LMW-glycosaminoglycans derived from K5 polysaccharide and process for their preparation |
ITMI20010397A1 (it) | 2001-02-27 | 2002-08-27 | Giorgio Zoppetti | Derivati altamente n,o-solfatati del polisaccaride k5 e loro preparazione |
ITMI20011633A1 (it) | 2001-07-27 | 2003-01-27 | San Raffaele Centro Fond | Uso di polisaccaridi batterici supersolfatati inibitori dell'hiv |
ITMI20012200A1 (it) | 2001-10-22 | 2003-04-22 | Ibsa Inst Biochimique Sa | Processo per la preparazione di condroitin solfati dal polisaccaride k4 e prodotti ottenuti |
MXPA04012805A (es) | 2002-06-18 | 2005-08-19 | Glycores 2000 Srl | Polisacarido sulfatado en exceso de bajo peso molecular. |
ITMI20032614A1 (it) | 2003-12-30 | 2005-06-30 | Altergon Sa | Nuova composizione comprendente cs |
-
2003
- 2003-12-17 IT IT002498A patent/ITMI20032498A1/it unknown
-
2004
- 2004-12-15 AT AT04806349T patent/ATE388169T1/de active
- 2004-12-15 EP EP04806349A patent/EP1694714B8/de not_active Not-in-force
- 2004-12-15 PT PT04806349T patent/PT1694714E/pt unknown
- 2004-12-15 DE DE602004012314T patent/DE602004012314T2/de active Active
- 2004-12-15 ES ES04806349T patent/ES2302065T3/es active Active
- 2004-12-15 US US10/582,687 patent/US7812151B2/en not_active Expired - Fee Related
- 2004-12-15 WO PCT/IB2004/004128 patent/WO2005058976A2/en active IP Right Grant
- 2004-12-15 JP JP2006544586A patent/JP4975443B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20070155694A1 (en) | 2007-07-05 |
US7812151B2 (en) | 2010-10-12 |
JP4975443B2 (ja) | 2012-07-11 |
DE602004012314T2 (de) | 2009-03-19 |
JP2007514817A (ja) | 2007-06-07 |
ES2302065T3 (es) | 2008-07-01 |
ATE388169T1 (de) | 2008-03-15 |
EP1694714A2 (de) | 2006-08-30 |
ITMI20032498A1 (it) | 2005-06-18 |
EP1694714B1 (de) | 2008-03-05 |
EP1694714B8 (de) | 2009-04-01 |
WO2005058976A2 (en) | 2005-06-30 |
WO2005058976A3 (en) | 2005-08-04 |
PT1694714E (pt) | 2008-05-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |