DE602004019530D1 - 2-pyridin alkyne derivaten und ihre verwendung für die schmerzbehandlung - Google Patents
2-pyridin alkyne derivaten und ihre verwendung für die schmerzbehandlungInfo
- Publication number
- DE602004019530D1 DE602004019530D1 DE602004019530T DE602004019530T DE602004019530D1 DE 602004019530 D1 DE602004019530 D1 DE 602004019530D1 DE 602004019530 T DE602004019530 T DE 602004019530T DE 602004019530 T DE602004019530 T DE 602004019530T DE 602004019530 D1 DE602004019530 D1 DE 602004019530D1
- Authority
- DE
- Germany
- Prior art keywords
- pyridine
- compound
- animal
- effective amount
- alkynyl compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48488103P | 2003-07-03 | 2003-07-03 | |
PCT/US2004/021246 WO2005007641A1 (en) | 2003-07-03 | 2004-07-01 | 2-pyridine alkyne derivatives useful for treating pain |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004019530D1 true DE602004019530D1 (de) | 2009-04-02 |
Family
ID=34079080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004019530T Active DE602004019530D1 (de) | 2003-07-03 | 2004-07-01 | 2-pyridin alkyne derivaten und ihre verwendung für die schmerzbehandlung |
Country Status (11)
Country | Link |
---|---|
US (2) | US7767699B2 (de) |
EP (1) | EP1641775B1 (de) |
AT (1) | ATE423111T1 (de) |
CY (1) | CY1109056T1 (de) |
DE (1) | DE602004019530D1 (de) |
DK (1) | DK1641775T3 (de) |
ES (1) | ES2322707T3 (de) |
PL (1) | PL1641775T3 (de) |
PT (1) | PT1641775E (de) |
SI (1) | SI1641775T1 (de) |
WO (1) | WO2005007641A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2322707T3 (es) | 2003-07-03 | 2009-06-25 | Euro-Celtique S.A. | Derivados de 2-piridina alquino utiles para tratar el dolor. |
US7713973B2 (en) | 2004-10-15 | 2010-05-11 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
GB0514017D0 (en) * | 2005-07-07 | 2005-08-17 | Ionix Pharmaceuticals Ltd | Chemical compounds |
US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
DE102005062985A1 (de) * | 2005-12-28 | 2007-07-05 | Grünenthal GmbH | Substituierte bis(hetero)aromatische N-Ethylpropiolamide und ihre Verwendung zur Herstellung von Arzneimitteln |
DE102005062991A1 (de) | 2005-12-28 | 2007-07-05 | Grünenthal GmbH | Substituierte Thiazole und ihre Verwendung zur Herstellung von Arzneimitteln |
DE102005062990A1 (de) * | 2005-12-28 | 2007-07-05 | Grünenthal GmbH | Substituierte Thiazole und ihre Verwendung zur Herstellung von Arzneimitteln |
JP2010505962A (ja) | 2006-10-09 | 2010-02-25 | 武田薬品工業株式会社 | キナーゼ阻害剤 |
GB201709459D0 (en) * | 2017-06-14 | 2017-07-26 | Intrabio Ltd | Treatment for migraine |
Family Cites Families (44)
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US598155A (en) * | 1898-02-01 | Machine for truing locomotive driving-wheels | ||
US3536809A (en) * | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
US3598123A (en) * | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4008719A (en) * | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
US5316759A (en) * | 1986-03-17 | 1994-05-31 | Robert J. Schaap | Agonist-antagonist combination to reduce the use of nicotine and other drugs |
DE3822792C2 (de) * | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
US5198459A (en) * | 1987-07-11 | 1993-03-30 | Sandoz Ltd. | Use of 5HT-3 antagonists in preventing or reducing dependency on dependency-inducing agents |
US5073543A (en) * | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
IT1229203B (it) * | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
CA2020437A1 (en) * | 1989-07-05 | 1991-01-06 | Yoshihide Fuse | Cinnamamide derivative |
US5120548A (en) * | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
US5075341A (en) * | 1989-12-01 | 1991-12-24 | The Mclean Hospital Corporation | Treatment for cocaine abuse |
US5733566A (en) * | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
MX9100513A (es) | 1990-08-06 | 1992-04-01 | Smith Kline French Lab | Compuestos |
US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
US6204284B1 (en) * | 1991-12-20 | 2001-03-20 | American Cyanamid Company | Use of 1-(substitutedphenyl)-3-azabicyclo[3.1.0]hexanes for the treatment of chemical dependencies |
US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
US5232934A (en) * | 1992-07-17 | 1993-08-03 | Warner-Lambert Co. | Method for the treatment of psychomotor stimulant addiction |
US5591767A (en) * | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
US5321012A (en) * | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
IT1270594B (it) * | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
US5556837A (en) * | 1994-08-01 | 1996-09-17 | Regeneron Pharmaceuticals Inc. | Methods for treating addictive disorders |
US5762925A (en) * | 1994-11-03 | 1998-06-09 | Sagen; Jacqueline | Preventing opiate tolerance by cellular implantation |
ATE301457T1 (de) * | 1995-06-12 | 2005-08-15 | Searle & Co | Mittel, enthaltend einen cyclooxygenase-2 inhibitor und einen 5-lipoxygenase inhibitor |
US5891889A (en) * | 1996-04-03 | 1999-04-06 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
AU5460598A (en) | 1996-11-15 | 1998-06-03 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Pharmaceutical compositions containing vanilloid agonists in combination with vanilloid antagonists |
TW544448B (en) * | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
ZA99607B (en) * | 1998-01-27 | 1999-07-27 | Rhone Poulenc Rorer Pharma | Substituted oxoazaheterocyclyl factor xa inhibitors. |
DE19822912A1 (de) * | 1998-05-22 | 1999-11-25 | Degussa | Verfahren zur Herstellung von 3-Amino-2-oxo-pyrrolidinen, neue Zwischenprodukte und deren Verwendung |
DE19841895A1 (de) * | 1998-09-11 | 2000-03-23 | Degussa | Neues Verfahren zur Herstellung von 3-Amino-2-oxo-pyrrolidinen, neue Zwischenprodukte und deren Verwendung |
EP1159264A2 (de) | 1999-02-11 | 2001-12-05 | Cor Therapeutics, Inc. | INHIBITOREN VON FAKTOR Xa |
US6109269A (en) * | 1999-04-30 | 2000-08-29 | Medtronic, Inc. | Method of treating addiction by brain infusion |
AU7354900A (en) | 1999-09-09 | 2001-04-10 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
US6544981B2 (en) | 2000-06-09 | 2003-04-08 | Bristol-Myers Squibb Company | Lactam inhibitors of factor Xa and method |
ES2345044T3 (es) * | 2002-02-01 | 2010-09-14 | Euro-Celtique S.A. | 2-piperazin-piridinas utiles para tratar el dolor. |
WO2003093236A1 (en) * | 2002-05-02 | 2003-11-13 | Euro-Celtique, S.A. | 1-(pyrid-2-yl)-piperazine compounds as metabotropic glutamate receptor inhibitor |
US6864261B2 (en) * | 2002-05-02 | 2005-03-08 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
CA2491079C (en) * | 2002-06-28 | 2011-10-04 | Donald J. Kyle | Therapeutic piperazine derivatives useful for treating pain |
US20040127501A1 (en) * | 2002-09-24 | 2004-07-01 | Zhengming Chen | Therapeutic agents useful for treating pain |
WO2004080411A2 (en) * | 2003-03-07 | 2004-09-23 | Neurocrine Biosciences, Inc. | Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto |
ES2322707T3 (es) | 2003-07-03 | 2009-06-25 | Euro-Celtique S.A. | Derivados de 2-piridina alquino utiles para tratar el dolor. |
-
2004
- 2004-07-01 ES ES04777409T patent/ES2322707T3/es active Active
- 2004-07-01 DK DK04777409T patent/DK1641775T3/da active
- 2004-07-01 PL PL04777409T patent/PL1641775T3/pl unknown
- 2004-07-01 DE DE602004019530T patent/DE602004019530D1/de active Active
- 2004-07-01 EP EP04777409A patent/EP1641775B1/de not_active Not-in-force
- 2004-07-01 SI SI200431105T patent/SI1641775T1/sl unknown
- 2004-07-01 PT PT04777409T patent/PT1641775E/pt unknown
- 2004-07-01 AT AT04777409T patent/ATE423111T1/de not_active IP Right Cessation
- 2004-07-01 WO PCT/US2004/021246 patent/WO2005007641A1/en active Application Filing
-
2005
- 2005-12-22 US US11/317,832 patent/US7767699B2/en active Active
-
2009
- 2009-04-29 CY CY20091100476T patent/CY1109056T1/el unknown
-
2010
- 2010-05-24 US US12/786,043 patent/US8058292B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP1641775B1 (de) | 2009-02-18 |
PT1641775E (pt) | 2009-04-23 |
SI1641775T1 (sl) | 2009-08-31 |
US7767699B2 (en) | 2010-08-03 |
US8058292B2 (en) | 2011-11-15 |
EP1641775A1 (de) | 2006-04-05 |
WO2005007641A1 (en) | 2005-01-27 |
DK1641775T3 (da) | 2009-04-20 |
US20100256111A1 (en) | 2010-10-07 |
PL1641775T3 (pl) | 2009-07-31 |
ES2322707T3 (es) | 2009-06-25 |
ATE423111T1 (de) | 2009-03-15 |
US20060235055A1 (en) | 2006-10-19 |
CY1109056T1 (el) | 2014-07-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |