DE602004030020D1 - Implantierbare oder einführbare medizinprodukte mit einem pfropf-copolymer zur kontrollierten abgabe von therapeutischen mitteln - Google Patents

Implantierbare oder einführbare medizinprodukte mit einem pfropf-copolymer zur kontrollierten abgabe von therapeutischen mitteln

Info

Publication number
DE602004030020D1
DE602004030020D1 DE602004030020T DE602004030020T DE602004030020D1 DE 602004030020 D1 DE602004030020 D1 DE 602004030020D1 DE 602004030020 T DE602004030020 T DE 602004030020T DE 602004030020 T DE602004030020 T DE 602004030020T DE 602004030020 D1 DE602004030020 D1 DE 602004030020D1
Authority
DE
Germany
Prior art keywords
introducable
peach
implantable
copolymer
therapeutic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004030020T
Other languages
English (en)
Inventor
Robert E Richard
Frederick H Strickler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Boston Scientific Ltd Barbados
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Ltd Barbados filed Critical Boston Scientific Ltd Barbados
Publication of DE602004030020D1 publication Critical patent/DE602004030020D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
DE602004030020T 2003-07-31 2004-07-29 Implantierbare oder einführbare medizinprodukte mit einem pfropf-copolymer zur kontrollierten abgabe von therapeutischen mitteln Active DE602004030020D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/632,413 US7357940B2 (en) 2003-07-31 2003-07-31 Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents
PCT/US2004/024530 WO2005011766A1 (en) 2003-07-31 2004-07-29 Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents

Publications (1)

Publication Number Publication Date
DE602004030020D1 true DE602004030020D1 (de) 2010-12-23

Family

ID=34104369

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004030020T Active DE602004030020D1 (de) 2003-07-31 2004-07-29 Implantierbare oder einführbare medizinprodukte mit einem pfropf-copolymer zur kontrollierten abgabe von therapeutischen mitteln

Country Status (7)

Country Link
US (1) US7357940B2 (de)
EP (1) EP1660144B1 (de)
JP (1) JP5001005B2 (de)
AU (1) AU2004261247A1 (de)
CA (1) CA2534078A1 (de)
DE (1) DE602004030020D1 (de)
WO (1) WO2005011766A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2289571B1 (de) 2003-03-28 2016-08-03 Innovational Holdings, LLC Implantierbare medizinische vorrichtung mit kontinuerlichem gradienten einer therapeutischen substanz
US7494665B1 (en) * 2004-07-30 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymers containing siloxane monomers
PT1781264E (pt) 2004-08-04 2013-10-16 Evonik Corp Métodos para o fabrico de dispositivis de administração e dispositivos para a mesma
US8075906B2 (en) * 2005-02-01 2011-12-13 Boston Scientific Scimed, Inc. Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species
US20060240059A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious eluting polymer blend and coating made from the same
US20060240060A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060240253A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Guidewire and tube with lubricious coating
US20060241000A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US8778375B2 (en) * 2005-04-29 2014-07-15 Advanced Cardiovascular Systems, Inc. Amorphous poly(D,L-lactide) coating
US8034874B2 (en) 2005-11-23 2011-10-11 Boston Scientific Scimed, Inc. Medical devices having polymeric regions that contain fluorocarbon-containing block copolymers
US8834912B2 (en) * 2005-12-30 2014-09-16 Boston Scientific Scimed, Inc. Medical devices having multiple charged layers
US7879086B2 (en) * 2006-04-20 2011-02-01 Boston Scientific Scimed, Inc. Medical device having a coating comprising an adhesion promoter
US7727541B2 (en) 2006-05-18 2010-06-01 Boston Scientific Scimed, Inc. Medical devices having polymeric regions based on vinyl ether block copolymers
US7914806B2 (en) * 2006-06-01 2011-03-29 Boston Scientific Scimed, Inc. Medical devices having improved performance
EP2386322B1 (de) * 2006-07-03 2017-12-27 Hemoteq AG Herstellung, Verfahren und Verwendung von wirkstofffreisetzenden Medizinprodukten zur permanenten Offenhaltung von Blutgefässen
US9474833B2 (en) * 2006-12-18 2016-10-25 Cook Medical Technologies Llc Stent graft with releasable therapeutic agent and soluble coating
DE112008000881A5 (de) 2007-01-21 2010-01-21 Hemoteq Ag Medizinprodukt zur Behandlung von Verschlüssen von Körperdurchgängen und zur Prävention drohender Wiederverschlüsse
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US20110129514A1 (en) * 2007-09-06 2011-06-02 Hossainy Syed F A Hygroscopic coating on a balloon device
US8124601B2 (en) * 2007-11-21 2012-02-28 Bristol-Myers Squibb Company Compounds for the treatment of Hepatitis C
JP5502751B2 (ja) 2007-12-20 2014-05-28 エボニック コーポレイション 低残留溶媒濃度を有する微粒子を調製するためのプロセス
DE102008006654A1 (de) * 2008-01-30 2009-08-06 Biotronik Vi Patent Ag Implantat mit einem Grundkörper aus einer biokorrodierbaren Legierung
WO2009102795A1 (en) * 2008-02-15 2009-08-20 University Of Southern Mississippi Monomers and polymers with covalently-attached active ingredients
US20090264478A1 (en) * 2008-04-18 2009-10-22 Warsaw Orthopedic, Inc. Sulfasalazine formulations in a biodegradable polymer carrier
WO2010033911A2 (en) * 2008-09-22 2010-03-25 Cardiac Pacemakers, Inc. Styrene-isobutylene copolymers and medical devices containing the same
WO2010033909A2 (en) 2008-09-22 2010-03-25 Boston Scientific Neuromodulation Corporation Implantable or insertable medical devices
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
US8500687B2 (en) 2008-09-25 2013-08-06 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
WO2010064222A2 (en) 2008-12-01 2010-06-10 University College Cork, National University Of Ireland, Cork Igf1 for myocardial repair
ES2550634T3 (es) 2009-07-10 2015-11-11 Boston Scientific Scimed, Inc. Uso de nanocristales para un balón de suministro de fármaco
US10080821B2 (en) 2009-07-17 2018-09-25 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
RU2545865C2 (ru) * 2009-09-22 2015-04-10 Евоник Корпорейшн Имплантируемые устройства с различными вариантами загрузки биологически активного компонента
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
EP2611476B1 (de) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Beschichtungsverfahren für wirkstofffreisetzungsballons mit wärmeinduziertem rewrap-gedächtnis
WO2013022458A1 (en) 2011-08-05 2013-02-14 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
US9056152B2 (en) 2011-08-25 2015-06-16 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
CN116407646A (zh) * 2021-12-30 2023-07-11 中南民族大学 一种双载体双药温度响应型给药系统的制备方法及其应用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196731A (en) 1978-03-17 1980-04-08 Baxter Travenol Laboratories, Inc. Silicone-containing thermoplastic polymers for medical uses
US4861830A (en) 1980-02-29 1989-08-29 Th. Goldschmidt Ag Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming
DE3245633A1 (de) 1982-12-09 1984-06-14 Serag-Wiessner Catgutfabriken GmbH, 8674 Naila Resorbierbares fasermaterial fuer die chirurgische wundversorgung, insbesondere fuer chirurgische naehzwecke
JPS59189153A (ja) * 1983-04-11 1984-10-26 Terumo Corp 樹脂組成物
US4584356A (en) * 1984-11-02 1986-04-22 General Electric Company Method for making silicone-organic block polymers
US4951656A (en) 1988-11-09 1990-08-28 Polysar Financial Services S.A. Orthopaedic structures from polymeric materials
US4946899A (en) 1988-12-16 1990-08-07 The University Of Akron Thermoplastic elastomers of isobutylene and process of preparation
US5304121A (en) 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5674192A (en) 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
US5258020A (en) 1990-09-14 1993-11-02 Michael Froix Method of using expandable polymeric stent with memory
DE4041525A1 (de) * 1990-12-22 1992-06-25 Roehm Gmbh Acrylat-methacrylat-pfropfpolymerisate
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
JPH05345016A (ja) * 1991-10-14 1993-12-27 Terumo Corp 血液適合性医療用材料
JPH05310868A (ja) * 1992-05-11 1993-11-22 Japan Synthetic Rubber Co Ltd 医療材用組成物
GB9222382D0 (en) * 1992-10-24 1992-12-09 Cranfield Inst Of Tech Polymeric biochemical compositions
US5716981A (en) 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
DE69434598T3 (de) 1993-07-29 2010-07-29 The United States Of America Represented By The Secretary, Department Of Health And Human Services Verwendung von Paclitaxel und seinen Derivaten zur Herstellung eines Medikaments für die Behandlung von Restenose
US5502092A (en) 1994-02-18 1996-03-26 Minnesota Mining And Manufacturing Company Biocompatible porous matrix of bioabsorbable material
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
AU732803B2 (en) * 1996-01-17 2001-05-03 National Starch And Chemical Investment Holding Corporation Adhesives resistant to skin-penetration enhancers
US5741331A (en) 1996-07-29 1998-04-21 Corvita Corporation Biostable elastomeric polymers having quaternary carbons
US5814329A (en) * 1996-11-12 1998-09-29 Polytherapeutics, Inc. Hydrophilic polystyrene graft copolymer vehicle for intravaginal administration of pharmacologically active agents
JP2001513124A (ja) 1997-02-21 2001-08-28 アドヒーシブズ リサーチ,インコーポレイテッド 感圧接着性薬剤透皮投与複合材とそれに使用する感圧接着性薬剤
US5879697A (en) 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
EP0893165A3 (de) * 1997-06-28 2000-09-20 Degussa-Hüls Aktiengesellschaft Bioaktive Beschichtung von Oberflächen unter Verwendung von Makroinitiatoren
US6280411B1 (en) 1998-05-18 2001-08-28 Scimed Life Systems, Inc. Localized delivery of drug agents
US6335029B1 (en) 1998-08-28 2002-01-01 Scimed Life Systems, Inc. Polymeric coatings for controlled delivery of active agents
US20020045706A1 (en) 1998-09-22 2002-04-18 Houston Michael R. Biomedical molding materials from semi-solid precursors
US6446671B2 (en) * 2000-08-04 2002-09-10 John G. Armenia Double wall safety hose
US6545097B2 (en) * 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
BR0209198A (pt) * 2001-04-26 2004-06-08 Control Delivery Sys Inc Métodos de sìntese de compostos contendo fenol
JP5073891B2 (ja) * 2001-07-16 2012-11-14 川澄化学工業株式会社 ステント及びステントグラフト
US8211455B2 (en) 2002-06-19 2012-07-03 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
US20030236513A1 (en) 2002-06-19 2003-12-25 Scimed Life Systems, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent

Also Published As

Publication number Publication date
CA2534078A1 (en) 2005-02-10
EP1660144A1 (de) 2006-05-31
US7357940B2 (en) 2008-04-15
JP2007513643A (ja) 2007-05-31
JP5001005B2 (ja) 2012-08-15
US20050025803A1 (en) 2005-02-03
WO2005011766A1 (en) 2005-02-10
EP1660144B1 (de) 2010-11-10
AU2004261247A1 (en) 2005-02-10

Similar Documents

Publication Publication Date Title
DE602004030020D1 (de) Implantierbare oder einführbare medizinprodukte mit einem pfropf-copolymer zur kontrollierten abgabe von therapeutischen mitteln
DE602004032040D1 (de) Implantierbare oder einführbare medizinprodukte mit einem silicon-copolymer zur kontrollierten abgabe von therapeutischen mitteln
ATE358505T1 (de) Beschichtete endovaskuläre vorrichtung
AU2003220317A8 (en) Methods and drug delivery systems for the treatment of orofacial diseases
AU2003287734A1 (en) Implantable device for delivering cardiac drug therapy
DE60202677D1 (de) Implantierbare medizinische vorrichtung mit kontrollierter freigabe von gasförmigen mitteln
ATE409064T1 (de) Selbstfixierende implantierbare gerüste zur verabreichung von biologischen oder pharmazeutischen substanzen
AU2003284018A1 (en) Medical device for neural stimulation and controlled drug delivery
ATE399553T1 (de) Pharmazeutische zusammensetzungen mit dextromethorphan und chinidin zur behandlung von neurologischen erkrankungen
ATE448812T1 (de) Beschichtung von stents mit verzögerter wirkstofffreisetzung
AU2003220312A1 (en) Patient controlled activation with implantable drug delivery devices
IL162719A0 (en) Drug delivery systems for the prevention and treatment of vascular diseases comprising rapamycin andderivatives thereof
AU2003295614A8 (en) Delivery of pharmaceutical agents via the human insulin receptor
AU2003243305A8 (en) Implantable medication delivery device
DE602004012816D1 (de) Selbstexpandierbarer Stent und Stenteinbringungssystem zur Behandlung von Gefässerkrankungen
DE59009462D1 (de) Implantierbare Vorrichtung zur dosierten Abgabe von Medikamenten in den menschlichen Körper.
HK1061534A1 (en) Implantable drug delivery pump
WO2004032881A3 (en) Implantation of encapsulated biological materials for treating diseases
ATE312636T1 (de) Infusion von flüssigkeiten in den menschlichen oder tierischen körper
HK1079993A1 (en) Drugs for treating vascular diseases
NO345140B1 (no) Anvendelse av humane IL-1beta bindende antistoffer og farmasøytiske sammensetninger inneholdende slike, for fremstilling av et medikament for behandling av juvenil reumatoid artritt
CY1119790T1 (el) Θεραπευτικο σχημα κλαδριβινης για την θεραπευτικη αντιμετωπιση της σκληρυνσης κατα πλακας
WO2003039539A3 (de) Verwendung von endothelin-rezeptor-antagonisten zur behandlung von tumorerkrankungen
AU2003271021A8 (en) Immunogen for preparation of therapeutic vaccines or drugs for treatment of hepatitis b and the producing method and use thereof
SG118275A1 (en) Polymers for the delivery of bioactive agents and methods of their preparation