DE602006006762D1 - Verbesserte ophthamologische bimatoprost-lösung - Google Patents

Verbesserte ophthamologische bimatoprost-lösung

Info

Publication number
DE602006006762D1
DE602006006762D1 DE602006006762T DE602006006762T DE602006006762D1 DE 602006006762 D1 DE602006006762 D1 DE 602006006762D1 DE 602006006762 T DE602006006762 T DE 602006006762T DE 602006006762 T DE602006006762 T DE 602006006762T DE 602006006762 D1 DE602006006762 D1 DE 602006006762D1
Authority
DE
Germany
Prior art keywords
ophthamological
improved
bimatoprost solution
bimatoprost
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006006762T
Other languages
English (en)
Inventor
Chin-Ming Chang
James N Chang
Rhett M Schiffman
R Scott Jordan
Joan-En Chang-Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36613401&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602006006762(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of DE602006006762D1 publication Critical patent/DE602006006762D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02Amines; Quaternary ammonium compounds
    • A01N33/12Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
DE602006006762T 2005-03-16 2006-03-14 Verbesserte ophthamologische bimatoprost-lösung Active DE602006006762D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/083,261 US7851504B2 (en) 2005-03-16 2005-03-16 Enhanced bimatoprost ophthalmic solution
PCT/US2006/009124 WO2006101839A2 (en) 2005-03-16 2006-03-14 Enhanced bimatoprost ophthalmic solution

Publications (1)

Publication Number Publication Date
DE602006006762D1 true DE602006006762D1 (de) 2009-06-25

Family

ID=36613401

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006006762T Active DE602006006762D1 (de) 2005-03-16 2006-03-14 Verbesserte ophthamologische bimatoprost-lösung

Country Status (23)

Country Link
US (10) US7851504B2 (de)
EP (1) EP1753434B2 (de)
JP (3) JP5367946B2 (de)
KR (2) KR101177598B1 (de)
CN (2) CN101137383B (de)
AR (1) AR055050A1 (de)
AT (1) ATE431152T1 (de)
AU (1) AU2006227757B2 (de)
BR (1) BRPI0607447B1 (de)
CA (1) CA2585691C (de)
DE (1) DE602006006762D1 (de)
DK (1) DK1753434T4 (de)
ES (1) ES2324058T5 (de)
HK (1) HK1104211A1 (de)
IL (1) IL185744A (de)
MX (1) MX2007011300A (de)
NO (1) NO337190B1 (de)
NZ (1) NZ560788A (de)
PL (1) PL1753434T5 (de)
RU (1) RU2363471C2 (de)
TW (1) TWI399207B (de)
WO (1) WO2006101839A2 (de)
ZA (1) ZA200707246B (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010102078A1 (en) 2009-03-04 2010-09-10 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
EP2389939A1 (de) * 2010-05-28 2011-11-30 Novagali Pharma S.A. Verwendung von Prostaglandinen F2alpha und Analoga zur Heilung von Horn- und Bindehautläsionen
PE20160904A1 (es) * 2009-12-22 2016-09-16 Allergan Inc Combinacion triple para reduccion de presion intraocular
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
EP2547323B1 (de) 2010-03-17 2016-01-27 Novaliq GmbH Pharmazeutische zusammensetzung zur behandlung erhöhten intraokulardrucks
EP2598117A2 (de) * 2010-07-29 2013-06-05 Allergan, Inc. Bimatoprostlösungen ohne konservierungsstoffe
US9061034B2 (en) * 2010-07-29 2015-06-23 Allergan, Inc. Preservative free bimatoprost and timolol solutions
SI2598118T1 (sl) 2010-07-29 2018-12-31 Allergan, Inc. Raztopine z bimatoprostom in timololom brez konzervansov
SG187770A1 (en) 2010-08-12 2013-03-28 Univ Nanyang Tech A liposomal formulation for ocular drug delivery
EP2462921A1 (de) 2010-11-11 2012-06-13 Novaliq GmbH Flüssige pharmazeutische Zusammensetzungen zur Behandlung einer Erkrankung der Hinterseite des Auges
WO2012163827A2 (en) * 2011-05-27 2012-12-06 Ratiopharm Gmbh Ophthalmic preparation comprising a pgf2alpha analogue
RU2474426C1 (ru) * 2011-12-26 2013-02-10 Учреждение Российской академии наук Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН Простамиды и их аналоги, обладающие нейрозащитным действием
EP4342537A2 (de) 2012-09-12 2024-03-27 Novaliq GmbH Semifluorierte alkanzusammensetzungen
PT2911623T (pt) 2012-10-26 2019-11-21 Forsight Vision5 Inc Sistema oftálmico para libertação prolongada de fármaco no olho
US9120738B2 (en) 2012-12-28 2015-09-01 Allergan, Inc. Crystalline forms of bimatoprost acid, methods for preparation, and methods for use thereof
US9308165B2 (en) * 2013-08-22 2016-04-12 Therapeutic Vision, Inc. Composition for treating ocular effects of diabetes
GR1008483B (el) 2013-12-23 2015-05-12 Rafarm Α.Ε.Β.Ε., Οφθαλμικη φαρμακευτικη συνθεση και μεθοδος για την παρασκευη αυτης
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
US9708079B2 (en) 2014-04-30 2017-07-18 The Boeing Company Mobile automated overhead assembly tool for aircraft structures
US10000298B2 (en) 2014-04-30 2018-06-19 The Boeing Company Metrology system for positioning assemblies
US10017277B2 (en) 2014-04-30 2018-07-10 The Boeing Company Apparatus, system, and method for supporting a wing assembly
US10118714B2 (en) 2014-04-30 2018-11-06 The Boeing Company System and method for positioning an automated assembly tool relative to a structure
US9776330B2 (en) 2014-04-30 2017-10-03 The Boeing Company Crawler robot and supporting platform
US9486917B2 (en) * 2014-04-30 2016-11-08 The Boeing Company Mobile automated assembly tool for aircraft structures
US10427254B2 (en) 2014-04-30 2019-10-01 The Boeing Company Flexible manufacturing for aircraft structures
EP3283004A4 (de) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Augeneinsatzzusammensetzung aus einem semikristallinen oder kristallinen pharmazeutischen wirkstoff
EP3103439B1 (de) 2015-06-09 2019-08-07 MEDproject Pharma-Entwicklungs- und Vertriebsgesellschaft mbH Tropfbares ophthalmisches bimatoprostgel
JP6602964B2 (ja) 2015-09-30 2019-11-06 ノバリック ゲーエムベーハー 半フッ素化化合物およびその組成物
EP4234523A1 (de) 2015-09-30 2023-08-30 Novaliq GmbH Semifluorierte verbindungen zur ophthalmologischen verabreichung
PL3442480T3 (pl) 2016-06-23 2020-04-30 Novaliq Gmbh Sposób podawania miejscowego
KR102275012B1 (ko) 2016-08-12 2021-07-07 실크 테크놀로지스 리미티드 염증 치료용 실크 유래 단백질
AU2017329772B2 (en) 2016-09-22 2023-02-02 Novaliq Gmbh Pharmaceutical compositions for use in the therapy of blepharitis
JP6869336B2 (ja) 2016-09-23 2021-05-12 ノバリック ゲーエムベーハー シクロスポリンを含む眼科用組成物
CA3063228C (en) 2017-05-11 2022-06-28 Nevakar Inc. Atropine pharmaceutical compositions
EP3621601A1 (de) 2017-05-12 2020-03-18 Novaliq GmbH Pharmazeutische zusammensetzungen mit semifluorierten alkanen zur behandlung von beschwerden im zusammenhang mit kontaktlinsen
USD841152S1 (en) 2017-06-27 2019-02-19 Monica S. Naylor Eye drop container
KR20200059272A (ko) 2017-09-27 2020-05-28 노바리크 게엠베하 안구 질환의 치료에서의 사용을 위한 라타노프로스트를 포함하는 안과적 조성물
WO2019068763A1 (en) 2017-10-04 2019-04-11 Novaliq Gmbh OPHTHALMIC COMPOSITIONS COMPRISING F6H8
WO2019166631A1 (en) 2018-03-02 2019-09-06 Novaliq Gmbh Pharmaceutical compositions comprising nebivolol
AU2019358249B2 (en) 2018-10-12 2024-02-22 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
US20220125801A1 (en) * 2019-03-06 2022-04-28 Mankind Pharma Ltd. Ophthalmic composition of bimatoprost
US20220175734A1 (en) * 2019-06-10 2022-06-09 Visus Therapeutics, Inc. Using parasympathomimetic drugs alone or, in combination with one or more alpha agonists in pseudophakic patients, to create multi-focality
CN114025768B (zh) 2019-06-28 2023-12-22 古鲁生物制药有限公司 促进毛发生长的药品
IT201900024961A1 (it) 2019-12-20 2021-06-20 Rafarm Uk Ltd Formulazioni di bimatoprost in soluzione allo 0,01% per il trattamento dell'ipertensione oculare
WO2021084522A1 (en) 2019-10-31 2021-05-06 Rafarm Uk Limited Bimatoprost 0.01% solution compositions for the treatment of ocular hypertension
US11400100B2 (en) 2019-12-11 2022-08-02 Somerset Therapeutics, Llc. Effective benzalkonium chloride-free bimatoprost ophthalmic compositions

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304907A (en) 1972-05-10 1981-12-08 The Upjohn Company Bicyclo lactone intermediates for prostaglandin analogs
JPS4969636A (de) 1972-11-07 1974-07-05
GB1402035A (en) 1972-12-07 1975-08-06 Ici Ltd Cyclopentane derivatives
FR2239458A1 (en) 1973-07-31 1975-02-28 Aries Robert Prostaglandin amides - with antilipolytic, gonadotrophic, luteolytic, hypotensive and other activities associated with prostaglandins
US4183870A (en) 1974-01-26 1980-01-15 May & Baker Limited Cyclopentane derivatives
NL7605381A (nl) 1975-05-26 1976-11-30 Schering Ag Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking.
US4073808A (en) 1975-12-29 1978-02-14 The Upjohn Company 2-Decarboxy-2-amino-methyl-PGA and 9-deoxy-9,10-didehydro-PGD analogs
US4128577A (en) 1975-12-29 1978-12-05 The Upjohn Company 15-Methyl- and 16-phenoxy-PGF2 α, amides
US4055602A (en) 1976-01-08 1977-10-25 The Upjohn Company 2-Decarboxy-2-hydroxy-methyl-5-oxa-17-phenyl-18,19,20-trinor-PGF-analogs
US4032576A (de) 1976-01-08 1977-06-28
IL51877A (en) 1976-06-01 1981-09-13 Carlo Erba Sa -nor-16-benzyl or phenoxy-13,14-dehydro-prostaglandins and process for their preparation
US4123441A (en) 1976-09-22 1978-10-31 The Upjohn Company Enlarged-hetero-ring prostacyclin analogs
DE2715838A1 (de) 1977-04-05 1978-10-19 Schering Ag Neue prostanderivate und verfahren zu ihrer herstellung
US4100192A (en) 1977-04-18 1978-07-11 The Upjohn Company Inter-phenylene-PG amides
US4163758A (en) 1977-09-09 1979-08-07 Sagami Chemical Research Center 2-Nitroethylcyclopentane compounds and process for preparing the same
US4171331A (en) 1978-06-05 1979-10-16 Miles Laboratories, Inc. 1 And 2-substituted analogues of certain prostaglandins
CA1141663A (en) 1979-09-06 1983-02-22 Yukihisa Ishii Ophthalmic solution for intraocular pressure adjustment
CH656877A5 (de) 1981-11-27 1986-07-31 Erba Farmitalia Optisch aktive oder racemische prostaglandinderivate.
US4599353A (en) 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
JPS591463A (ja) 1982-06-28 1984-01-06 Ono Pharmaceut Co Ltd 新規なプロスタグランジンd類似化合物
EP0102230B1 (de) 1982-08-24 1987-04-29 Teijin Limited 6-Nitroprostaglandinderivate, Verfahren zu ihrer Herstellung und ihre Anwendung
JPS61126069A (ja) 1984-11-21 1986-06-13 Res Dev Corp Of Japan プロスタグランジン誘導体
JPH0611715B2 (ja) 1986-03-17 1994-02-16 花王株式会社 経皮吸収促進剤およびこれを含有する外用剤
US4824857A (en) 1986-05-16 1989-04-25 Yasumasa Goh Use of prostaglandin D2 -active substances
ES2186670T3 (es) 1988-09-06 2003-05-16 Pharmacia Ab Derivados de prostaglandina para el tratamiento del glaucoma o la hipertension ocular.
US5281591A (en) 1989-05-22 1994-01-25 Allergan, Inc. Combinations of selective alpha-adrenergic agonists and antagonists useful in lowering intraocular pressure
US4994274A (en) 1989-07-27 1991-02-19 Allergan, Inc. Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using
US5034413A (en) 1989-07-27 1991-07-23 Allergan, Inc. Intraocular pressure reducing 9,11-diacyl prostaglandins
CA2039420C (en) 1990-04-04 1996-12-10 Ryuji Ueno Treatment of cataract with 15-keto-prostaglandin compounds
US5270049A (en) 1990-11-09 1993-12-14 Allergan, Inc. 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives
IT1256824B (it) * 1992-05-14 1995-12-21 Varian Spa Unita' rivelatrice di elio perfezionata.
US5352708A (en) 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5972991A (en) 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US5688819A (en) 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5510383A (en) 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US5545665A (en) 1993-12-28 1996-08-13 Allergan Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
US5474979A (en) 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
IT1313610B1 (it) 1999-08-09 2002-09-09 S I F I Societa Ind Farmaceuti Processo per la preparazione di formulazioni acquose per uso oftalmico
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020035148A1 (en) 2000-07-20 2002-03-21 Ryuji Ueno Treatment of ocular hypertension
US20020177625A1 (en) 2001-04-28 2002-11-28 The Regents Of The University Of California, A California Corporation Class of glaucoma drugs to enhance aqueous humor outflow and lower intra-ocular pressure
US6743439B1 (en) 2001-06-27 2004-06-01 Alcon, Inc. Ophthalmic compositions containing copolymers of sulfonated styrene and maleic anhydride
US6743493B2 (en) * 2001-09-11 2004-06-01 Ward-Kraft, Inc. Composite form with imprintable magnetic card
US20040029771A1 (en) 2002-02-28 2004-02-12 Icagen, Inc. Methods for treating diseases related to intraocular pressure
JP4836401B2 (ja) 2002-04-01 2011-12-14 ロート製薬株式会社 眼科用組成物
US6864282B2 (en) 2002-08-05 2005-03-08 Allergan, Inc. 9,11-cycloendoperoxide pro-drugs of prostaglandin analogues for treatment of ocular hypertension and glaucoma
US20040079671A1 (en) 2002-08-29 2004-04-29 Paramita Bandyopadhyay Medicinal product packaging
KR101182496B1 (ko) 2002-09-09 2012-09-12 산텐 세이야꾸 가부시키가이샤 라타노프로스트를 유효 성분으로 하는 투명한 점안액
US20040115234A1 (en) 2002-09-24 2004-06-17 Gewirtz Joan T. Cosmetic composition
US6933289B2 (en) 2003-07-01 2005-08-23 Allergan, Inc. Inhibition of irritating side effects associated with use of a topical ophthalmic medication
US20050049311A1 (en) 2003-09-03 2005-03-03 Pharmacia & Upjohn Company Medicinal products comprising prostaglandin compositions and methods of packaging such compositions
US20060141049A1 (en) 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20050276867A1 (en) 2004-06-09 2005-12-15 Allergan, Inc. Stabilized compositions comprising a therapeutically active agent and an oxidizing preservative
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
WO2010102078A1 (en) 2009-03-04 2010-09-10 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
SI2046382T1 (sl) 2006-07-10 2016-12-30 ESBATech an Alcon Biomedical Research Unit LLC Protitelesa scFv, ki prehajajo epitelijske in/ali endotelijske plasti

Also Published As

Publication number Publication date
IL185744A (en) 2015-09-24
AU2006227757B2 (en) 2011-07-14
US20160250225A1 (en) 2016-09-01
AU2006227757A1 (en) 2006-09-28
CA2585691C (en) 2009-05-19
TWI399207B (zh) 2013-06-21
US20120142782A1 (en) 2012-06-07
JP5899267B2 (ja) 2016-04-06
US20130102678A1 (en) 2013-04-25
US8299118B2 (en) 2012-10-30
CN101137383B (zh) 2011-06-15
JP5367946B2 (ja) 2013-12-11
US8338479B2 (en) 2012-12-25
US20090149546A1 (en) 2009-06-11
CN101137383A (zh) 2008-03-05
EP1753434B2 (de) 2017-12-27
US8586630B2 (en) 2013-11-19
ES2324058T3 (es) 2009-07-29
RU2363471C2 (ru) 2009-08-10
US20110124737A1 (en) 2011-05-26
KR20070113292A (ko) 2007-11-28
ZA200707246B (en) 2008-09-25
JP2008511539A (ja) 2008-04-17
US20150087713A1 (en) 2015-03-26
RU2007133919A (ru) 2009-04-27
US8772338B2 (en) 2014-07-08
JP5563515B2 (ja) 2014-07-30
JP2011148827A (ja) 2011-08-04
NZ560788A (en) 2010-12-24
DK1753434T3 (da) 2009-08-03
CA2585691A1 (en) 2006-09-28
PL1753434T3 (pl) 2009-09-30
TW200700070A (en) 2007-01-01
KR20120068051A (ko) 2012-06-26
EP1753434B1 (de) 2009-05-13
NO337190B1 (no) 2016-02-08
NO20074390L (no) 2007-10-15
MX2007011300A (es) 2007-10-05
PL1753434T5 (pl) 2018-05-30
US20140100287A1 (en) 2014-04-10
US8933120B2 (en) 2015-01-13
IL185744A0 (en) 2008-01-06
KR101177598B1 (ko) 2012-08-27
HK1104211A1 (en) 2008-01-11
US20130203854A1 (en) 2013-08-08
ES2324058T5 (es) 2018-05-22
US20120142783A1 (en) 2012-06-07
BRPI0607447B1 (pt) 2022-09-27
CN102240292A (zh) 2011-11-16
US7851504B2 (en) 2010-12-14
US20060211770A1 (en) 2006-09-21
CN102240292B (zh) 2018-08-07
US8309605B2 (en) 2012-11-13
BRPI0607447A2 (pt) 2009-09-01
JP2014144983A (ja) 2014-08-14
WO2006101839A2 (en) 2006-09-28
US8278353B2 (en) 2012-10-02
ATE431152T1 (de) 2009-05-15
EP1753434A2 (de) 2007-02-21
WO2006101839A3 (en) 2006-12-07
AR055050A1 (es) 2007-08-01
DK1753434T4 (en) 2018-03-05

Similar Documents

Publication Publication Date Title
ATE431152T1 (de) Verbesserte ophthamologische bimatoprost-lösung
NL300953I2 (nl) darvadstrocel
DE602006021176D1 (de) Endoskop
DE602006020876D1 (de) Endoskop
DK1898744T3 (da) Tandbørste
DE602005026825D1 (de) Endoskop
DK1968631T3 (da) Vaccine
ATE408603T1 (de) Pyrazolylcarboxanilide
CR9974A (es) Gavión
DE602006004919D1 (de) Endoskopsystem
DK1885966T3 (da) Forbedret hoved-t-forbindelse
DK1883469T3 (da) Katalysatorfremstilling
ATE549324T1 (de) Tetrahydrobenzoxazine
DE602005027499D1 (de) Endoskopsystem
DE602006006131D1 (de) Endoskop
DE602005026124D1 (de) Endoskop
DE112006002964A5 (de) Zweirichtungsreflektanzverteilungsmessgerät
DE112006001343A5 (de) Patientenauflage
DE602006007774D1 (de) Zahnreinigungsmittel
DE502005005839D1 (de) Feldgeerät
BRPI0620820A2 (pt) dentifrício
BRPI0620807A2 (pt) dentifrício
DE502006006589D1 (de) Teils
ATE485368T1 (de) Hiv - impfung
DE102005052834B8 (de) Punktschweißklebverbindung

Legal Events

Date Code Title Description
8363 Opposition against the patent