DE602006019261D1 - Verfahren zur sequenzierung einer polynukleotidmatrize - Google Patents
Verfahren zur sequenzierung einer polynukleotidmatrizeInfo
- Publication number
- DE602006019261D1 DE602006019261D1 DE602006019261T DE602006019261T DE602006019261D1 DE 602006019261 D1 DE602006019261 D1 DE 602006019261D1 DE 602006019261 T DE602006019261 T DE 602006019261T DE 602006019261 T DE602006019261 T DE 602006019261T DE 602006019261 D1 DE602006019261 D1 DE 602006019261D1
- Authority
- DE
- Germany
- Prior art keywords
- sequencing
- matrize
- polynucleotide
- double
- stranded polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0514910.9A GB0514910D0 (en) | 2005-07-20 | 2005-07-20 | Method for sequencing a polynucleotide template |
| PCT/GB2006/002690 WO2007010252A1 (en) | 2005-07-20 | 2006-07-20 | Method for sequencing a polynucleotide template |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006019261D1 true DE602006019261D1 (de) | 2011-02-10 |
Family
ID=34897536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006019261T Active DE602006019261D1 (de) | 2005-07-20 | 2006-07-20 | Verfahren zur sequenzierung einer polynukleotidmatrize |
Country Status (6)
| Country | Link |
|---|---|
| US (8) | US8017335B2 (de) |
| EP (1) | EP1910560B1 (de) |
| AT (1) | ATE493513T1 (de) |
| DE (1) | DE602006019261D1 (de) |
| GB (1) | GB0514910D0 (de) |
| WO (1) | WO2007010252A1 (de) |
Families Citing this family (107)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0514935D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Methods for sequencing a polynucleotide template |
| GB0514910D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Method for sequencing a polynucleotide template |
| WO2007091077A1 (en) * | 2006-02-08 | 2007-08-16 | Solexa Limited | Method for sequencing a polynucleotide template |
| US8053191B2 (en) | 2006-08-31 | 2011-11-08 | Westend Asset Clearinghouse Company, Llc | Iterative nucleic acid assembly using activation of vector-encoded traits |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| US20090062132A1 (en) * | 2007-08-29 | 2009-03-05 | Borner Scott R | Alternative nucleic acid sequencing methods |
| US8263367B2 (en) | 2008-01-25 | 2012-09-11 | Agency For Science, Technology And Research | Nucleic acid interaction analysis |
| US8202691B2 (en) | 2008-01-25 | 2012-06-19 | Illumina, Inc. | Uniform fragmentation of DNA using binding proteins |
| US7767400B2 (en) * | 2008-02-03 | 2010-08-03 | Helicos Biosciences Corporation | Paired-end reads in sequencing by synthesis |
| WO2010003132A1 (en) | 2008-07-02 | 2010-01-07 | Illumina Cambridge Ltd. | Using populations of beads for the fabrication of arrays on surfaces |
| US20100184045A1 (en) * | 2008-09-23 | 2010-07-22 | Helicos Biosciences Corporation | Methods for sequencing degraded or modified nucleic acids |
| WO2010038042A1 (en) * | 2008-10-02 | 2010-04-08 | Illumina Cambridge Ltd. | Nucleic acid sample enrichment for sequencing applications |
| WO2010048337A2 (en) | 2008-10-22 | 2010-04-29 | Illumina, Inc. | Preservation of information related to genomic dna methylation |
| EP2379748A4 (de) | 2008-12-23 | 2012-08-29 | Illumina Inc | Multibase-freisetzung für lange auslesevorgänge bei squenzierungen mittels syntheseprotokollen |
| US9309557B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Nucleic acid amplification |
| US9309566B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Methods, compositions, systems, apparatuses and kits for nucleic acid amplification |
| US9334531B2 (en) | 2010-12-17 | 2016-05-10 | Life Technologies Corporation | Nucleic acid amplification |
| US10036063B2 (en) | 2009-07-24 | 2018-07-31 | Illumina, Inc. | Method for sequencing a polynucleotide template |
| ES2595055T3 (es) | 2009-08-25 | 2016-12-27 | Illumina, Inc. | Métodos para seleccionar y amplificar polinucleótidos |
| WO2011053987A1 (en) * | 2009-11-02 | 2011-05-05 | Nugen Technologies, Inc. | Compositions and methods for targeted nucleic acid sequence selection and amplification |
| SG10201407883PA (en) | 2009-12-07 | 2015-01-29 | Illumina Inc | Multi-sample indexing for multiplex genotyping |
| US9029103B2 (en) | 2010-08-27 | 2015-05-12 | Illumina Cambridge Limited | Methods for sequencing polynucleotides |
| US8483969B2 (en) | 2010-09-17 | 2013-07-09 | Illuminia, Inc. | Variation analysis for multiple templates on a solid support |
| WO2012050920A1 (en) | 2010-09-29 | 2012-04-19 | Illumina, Inc. | Compositions and methods for sequencing nucleic acids |
| IL280133B2 (en) * | 2010-11-12 | 2023-04-01 | Gen9 Inc | Methods and devices for the synthesis of nucleic acids |
| US10457935B2 (en) | 2010-11-12 | 2019-10-29 | Gen9, Inc. | Protein arrays and methods of using and making the same |
| EP3564392B1 (de) | 2010-12-17 | 2021-11-24 | Life Technologies Corporation | Verfahren für nukleinsäureamplifikation |
| US8951781B2 (en) | 2011-01-10 | 2015-02-10 | Illumina, Inc. | Systems, methods, and apparatuses to image a sample for biological or chemical analysis |
| EP3246416A1 (de) | 2011-04-15 | 2017-11-22 | The Johns Hopkins University | Sicheres sortierungssystem |
| ES2737957T3 (es) | 2011-08-26 | 2020-01-17 | Gen9 Inc | Composiciones y métodos para el ensamblaje de alta fidelidad de ácidos nucleicos |
| GB2497838A (en) | 2011-10-19 | 2013-06-26 | Nugen Technologies Inc | Compositions and methods for directional nucleic acid amplification and sequencing |
| CN105861487B (zh) | 2012-01-26 | 2020-05-05 | 纽亘技术公司 | 用于靶向核酸序列富集和高效文库产生的组合物和方法 |
| US9150853B2 (en) | 2012-03-21 | 2015-10-06 | Gen9, Inc. | Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis |
| CN104603286B (zh) | 2012-04-24 | 2020-07-31 | Gen9股份有限公司 | 在体外克隆中分选核酸和多重制备物的方法 |
| CN104619894B (zh) | 2012-06-18 | 2017-06-06 | 纽亘技术公司 | 用于非期望核酸序列的阴性选择的组合物和方法 |
| LT2864531T (lt) | 2012-06-25 | 2019-03-12 | Gen9, Inc. | Nukleorūgšties konstravimo ir aukšto produktyvumo sekvenavimo būdai |
| US20150011396A1 (en) | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
| US9092401B2 (en) | 2012-10-31 | 2015-07-28 | Counsyl, Inc. | System and methods for detecting genetic variation |
| EP3243937A1 (de) | 2012-07-17 | 2017-11-15 | Counsyl, Inc. | System und verfahren zur erkennung von genetischen variationen |
| EP2888371B1 (de) * | 2012-08-24 | 2017-08-02 | Life Technologies Corporation | Verfahren, zusammensetzungen, systeme, vorrichtungen und kits für nukleinsäuresequenzierung mit gepaartem ende |
| US9181583B2 (en) | 2012-10-23 | 2015-11-10 | Illumina, Inc. | HLA typing using selective amplification and sequencing |
| EP2912468B1 (de) | 2012-10-29 | 2018-09-12 | The Johns Hopkins University | Papanicolaou-test für ovarial- und endometriumkarzinome |
| US9146248B2 (en) | 2013-03-14 | 2015-09-29 | Intelligent Bio-Systems, Inc. | Apparatus and methods for purging flow cells in nucleic acid sequencing instruments |
| EP2971130A4 (de) | 2013-03-15 | 2016-10-05 | Nugen Technologies Inc | Sequentielle sequenzierung |
| US9591268B2 (en) | 2013-03-15 | 2017-03-07 | Qiagen Waltham, Inc. | Flow cell alignment methods and systems |
| EP3597772A1 (de) | 2013-04-17 | 2020-01-22 | Agency For Science, Technology And Research | Verfahren zur erzeugung erweiterter sequenzauslesungen |
| EP3017063B1 (de) | 2013-07-03 | 2017-04-05 | Illumina, Inc. | Sequenzierung durch orthogonale synthese |
| WO2015073711A1 (en) | 2013-11-13 | 2015-05-21 | Nugen Technologies, Inc. | Compositions and methods for identification of a duplicate sequencing read |
| WO2015131107A1 (en) | 2014-02-28 | 2015-09-03 | Nugen Technologies, Inc. | Reduced representation bisulfite sequencing with diversity adaptors |
| US20160085910A1 (en) | 2014-09-18 | 2016-03-24 | Illumina, Inc. | Methods and systems for analyzing nucleic acid sequencing data |
| US10233490B2 (en) | 2014-11-21 | 2019-03-19 | Metabiotech Corporation | Methods for assembling and reading nucleic acid sequences from mixed populations |
| WO2016090266A1 (en) | 2014-12-05 | 2016-06-09 | Amyris, Inc. | High-throughput sequencing of polynucleotides |
| EP3303614B1 (de) | 2015-05-29 | 2020-03-11 | Illumina Cambridge Limited | Verbesserte verwendung von oberflächenprimern bei clustern |
| IL255445B (en) | 2015-07-30 | 2022-07-01 | Illumina Inc | Removal of orthogonal blocking of nucleotides |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| CN116240272A (zh) | 2015-11-19 | 2023-06-09 | 赛纳生物科技(北京)有限公司 | 一种用于获得多核苷酸的序列信息的试剂盒或系统 |
| BR112019009949A2 (pt) | 2016-11-16 | 2019-08-20 | Illumina Inc | método implantado por computador para validar chamadas de variante e sistema para validar chamadas de variante |
| US20210072255A1 (en) | 2016-12-16 | 2021-03-11 | The Brigham And Women's Hospital, Inc. | System and method for protein corona sensor array for early detection of diseases |
| WO2018197950A1 (en) | 2017-04-23 | 2018-11-01 | Illumina Cambridge Limited | Compositions and methods for improving sample identification in indexed nucleic acid libraries |
| DK3872187T3 (da) | 2017-04-23 | 2022-12-05 | Illumina Cambridge Ltd | Sammensætninger og fremgangsmåder til forbedring af prøveidentificering i indekserede nukleinsyrebiblioteker |
| ES2937929T3 (es) | 2017-04-23 | 2023-04-03 | Illumina Inc | Composiciones y métodos para mejorar la identificación de muestras en bibliotecas de ácido nucleico indexadas |
| CN113627458A (zh) | 2017-10-16 | 2021-11-09 | 因美纳有限公司 | 基于循环神经网络的变体致病性分类器 |
| BR112019027609A2 (pt) | 2017-10-16 | 2020-07-21 | Illumina, Inc. | método implementado em rede neural de treinamento de um detector de sítio de splice que identifica sítios de splice em sequências genômicas, previsor de sítio de splice treinado e sistema |
| US11099202B2 (en) | 2017-10-20 | 2021-08-24 | Tecan Genomics, Inc. | Reagent delivery system |
| US20190206510A1 (en) | 2017-11-30 | 2019-07-04 | Illumina, Inc. | Validation methods and systems for sequence variant calls |
| NZ759659A (en) | 2018-01-15 | 2022-07-01 | Illumina Inc | Deep learning-based variant classifier |
| WO2019200338A1 (en) | 2018-04-12 | 2019-10-17 | Illumina, Inc. | Variant classifier based on deep neural networks |
| US20200251183A1 (en) | 2018-07-11 | 2020-08-06 | Illumina, Inc. | Deep Learning-Based Framework for Identifying Sequence Patterns that Cause Sequence-Specific Errors (SSEs) |
| SG10202108013QA (en) | 2018-10-15 | 2021-09-29 | Illumina Inc | Deep learning-based techniques for pre-training deep convolutional neural networks |
| KR20230155589A (ko) | 2018-11-07 | 2023-11-10 | 시어 인코퍼레이티드 | 단백질 코로나 분석을 위한 조성물, 방법 및 시스템 및 그것들의 용도 |
| JP2022511207A (ja) | 2018-12-05 | 2022-01-31 | イルミナ ケンブリッジ リミテッド | ブリッジ増幅によるクラスタ生成のための方法および組成物 |
| AU2019411272A1 (en) | 2018-12-18 | 2021-01-07 | Illumina Cambridge Limited | Methods and compositions for paired end sequencing using a single surface primer |
| NL2023310B1 (en) | 2019-03-21 | 2020-09-28 | Illumina Inc | Training data generation for artificial intelligence-based sequencing |
| NL2023312B1 (en) | 2019-03-21 | 2020-09-28 | Illumina Inc | Artificial intelligence-based base calling |
| NL2023314B1 (en) | 2019-03-21 | 2020-09-28 | Illumina Inc | Artificial intelligence-based quality scoring |
| WO2020205296A1 (en) | 2019-03-21 | 2020-10-08 | Illumina, Inc. | Artificial intelligence-based generation of sequencing metadata |
| NL2023316B1 (en) | 2019-03-21 | 2020-09-28 | Illumina Inc | Artificial intelligence-based sequencing |
| NL2023311B9 (en) | 2019-03-21 | 2021-03-12 | Illumina Inc | Artificial intelligence-based generation of sequencing metadata |
| US11210554B2 (en) | 2019-03-21 | 2021-12-28 | Illumina, Inc. | Artificial intelligence-based generation of sequencing metadata |
| AU2020326698A1 (en) | 2019-08-05 | 2022-02-24 | Seer, Inc. | Systems and methods for sample preparation, data generation, and protein corona analysis |
| US20210265018A1 (en) | 2020-02-20 | 2021-08-26 | Illumina, Inc. | Knowledge Distillation and Gradient Pruning-Based Compression of Artificial Intelligence-Based Base Caller |
| CN115516104A (zh) | 2020-03-03 | 2022-12-23 | 加利福尼亚太平洋生物科学股份有限公司 | 用于对双链核酸进行测序的方法和组合物 |
| ES2965266T3 (es) | 2020-03-09 | 2024-04-11 | Illumina Inc | Métodos para la secuenciación de polinucleótidos |
| US11188778B1 (en) | 2020-05-05 | 2021-11-30 | Illumina, Inc. | Equalization-based image processing and spatial crosstalk attenuator |
| CA3190719A1 (en) | 2020-08-25 | 2022-03-03 | Daniel Hornburg | Compositions and methods for assaying proteins and nucleic acids |
| US11859241B2 (en) | 2021-06-17 | 2024-01-02 | Element Biosciences, Inc. | Compositions and methods for pairwise sequencing |
| US11535892B1 (en) | 2021-06-17 | 2022-12-27 | Element Biosciences, Inc. | Compositions and methods for pairwise sequencing |
| KR20240031968A (ko) | 2021-07-19 | 2024-03-08 | 일루미나, 인코포레이티드 | 염기 호출에 대한 보간 및 적응을 갖는 강도 추출 |
| US11455487B1 (en) | 2021-10-26 | 2022-09-27 | Illumina Software, Inc. | Intensity extraction and crosstalk attenuation using interpolation and adaptation for base calling |
| WO2023049215A1 (en) | 2021-09-22 | 2023-03-30 | Illumina, Inc. | Compressed state-based base calling |
| AU2022409487A1 (en) | 2021-12-16 | 2024-01-18 | Illumina, Inc. | Hybrid clustering |
| AU2022413263A1 (en) | 2021-12-17 | 2024-01-18 | Illumina, Inc. | Orthogonal hybridization |
| CN114457146A (zh) * | 2022-01-28 | 2022-05-10 | 赛纳生物科技(北京)有限公司 | 一种固相介质表面双端扩增测序的方法 |
| CA3223653A1 (en) | 2022-03-15 | 2023-09-21 | Aathavan KARUNAKARAN | Concurrent sequencing of forward and reverse complement strands on separate polynucleotides for methylation detection |
| WO2023175026A1 (en) | 2022-03-15 | 2023-09-21 | Illumina, Inc. | Methods of determining sequence information |
| US20230343414A1 (en) | 2022-03-25 | 2023-10-26 | Illumina, Inc. | Sequence-to-sequence base calling |
| AU2023246691A1 (en) * | 2022-03-30 | 2024-01-18 | Illumina, Inc. | Methods for chemical cleavage of surface-bound polynucleotides |
| WO2023240093A1 (en) | 2022-06-06 | 2023-12-14 | Element Biosciences, Inc. | Methods for assembling and reading nucleic acid sequences from mixed populations |
| US20230407386A1 (en) | 2022-06-09 | 2023-12-21 | Illumina, Inc. | Dependence of base calling on flow cell tilt |
| WO2024033174A1 (en) | 2022-08-12 | 2024-02-15 | Miltenyi Biotec B.V. & Co. KG | Barcoding of nucleic acids from single cells |
| WO2024057280A1 (en) | 2022-09-16 | 2024-03-21 | Illumina Cambridge Limited | Nanoparticle with polynucleotide binding site and method of making thereof |
| WO2024061799A1 (en) | 2022-09-19 | 2024-03-28 | Illumina, Inc. | Deformable polymers comprising immobilised primers |
| US20240102067A1 (en) | 2022-09-26 | 2024-03-28 | Illumina, Inc. | Resynthesis Kits and Methods |
| US20240110234A1 (en) | 2022-09-30 | 2024-04-04 | Illumina, Inc. | Amplification Compositions and Methods |
| US20240124929A1 (en) | 2022-09-30 | 2024-04-18 | Illumina, Inc. | Mesophilic compositions for nucleic acid amplification |
| US20240124914A1 (en) | 2022-09-30 | 2024-04-18 | Illumina, Inc. | Thermophilic compositions for nucleic acid amplification |
| US20240110221A1 (en) | 2022-09-30 | 2024-04-04 | Illumina, Inc. | Methods of modulating clustering kinetics |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB205153A (en) | 1922-07-04 | 1923-10-04 | Charles Ashton Henry Bullock | Improvements in type setting apparatus |
| GB522310A (en) | 1938-12-02 | 1940-06-14 | Corning Glass Works | Improvements in wall structures and in glass construction blocks therefor |
| US4292503A (en) | 1979-05-14 | 1981-09-29 | Emerson Electric Co. | Split-band electric heater |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| EP0224126A3 (de) | 1985-11-25 | 1989-02-01 | The University of Calgary | Kovalent gekoppelte komplementäre Oligodeoxynukleotide zur Verwendung als "Primer Linkers" bei Sequenzierung von Nukleinsäuren |
| CA1340843C (en) | 1987-07-31 | 1999-12-07 | J. Lawrence Burg | Selective amplification of target polynucleotide sequences |
| SE8801070D0 (sv) | 1988-03-23 | 1988-03-23 | Pharmacia Ab | Method for immobilizing a dna sequence on a solid support |
| US6107023A (en) * | 1988-06-17 | 2000-08-22 | Genelabs Technologies, Inc. | DNA amplification and subtraction techniques |
| GB8818020D0 (en) | 1988-07-28 | 1988-09-01 | Ici Plc | Method for amplification of nucleotide sequences |
| CA2004326A1 (en) | 1988-12-23 | 1990-06-23 | Nanibushan Dattagupta | Assay of sequences using amplified genes |
| US5629158A (en) * | 1989-03-22 | 1997-05-13 | Cemu Bitecknik Ab | Solid phase diagnosis of medical conditions |
| US5800992A (en) * | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5547839A (en) * | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| US5302509A (en) * | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
| JP3096722B2 (ja) | 1990-01-17 | 2000-10-10 | 日本ケミカルリサーチ株式会社 | ポリメラーゼ・チェーン・リアクション用プライマーの作製法およびそれを用いるｄｎａの増幅法 |
| US5118604A (en) * | 1990-06-15 | 1992-06-02 | Yale University | Restriction-fragment DNA probes and probe clusters |
| WO1993004199A2 (en) | 1991-08-20 | 1993-03-04 | Scientific Generics Limited | Methods of detecting or quantitating nucleic acids and of producing labelled immobilised nucleic acids |
| WO1993006239A1 (en) | 1991-09-24 | 1993-04-01 | Keygene N.V. | Selective restriction fragment amplification: a general method for dna fingerprinting |
| AU3728093A (en) * | 1992-02-19 | 1993-09-13 | Public Health Research Institute Of The City Of New York, Inc., The | Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids |
| US5849544A (en) | 1992-07-24 | 1998-12-15 | University Of Australia | Amplification and detection process |
| RU2048522C1 (ru) * | 1992-10-14 | 1995-11-20 | Институт белка РАН | Способ размножения нуклеиновых кислот, способ их экспрессии и среда для их осуществления |
| JPH07203998A (ja) | 1994-01-26 | 1995-08-08 | Hamamatsu Photonics Kk | 核酸塩基配列決定方法 |
| NZ287118A (en) | 1994-05-28 | 1999-01-28 | Tepnel Medical Ltd | Method of detecting and amplifying oligonucleotides |
| US6060288A (en) | 1994-08-03 | 2000-05-09 | Mosaic Technologies | Method for performing amplification of nucleic acid on supports |
| US5641658A (en) | 1994-08-03 | 1997-06-24 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid with two primers bound to a single solid support |
| US6090592A (en) * | 1994-08-03 | 2000-07-18 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid on supports |
| JPH11503611A (ja) | 1995-04-11 | 1999-03-30 | トラスティーズ・オブ・ボストン・ユニバーシティ | 生体高分子の固相配列決定法 |
| DE19515552A1 (de) * | 1995-04-27 | 1996-10-31 | Europ Lab Molekularbiolog | Simultane Sequenzierung von Nukleinsäuren |
| SE9504099D0 (sv) * | 1995-11-16 | 1995-11-16 | Pharmacia Biotech Ab | A method of sequencing |
| US5935788A (en) * | 1996-06-25 | 1999-08-10 | Lifespan Biosciences, Inc. | Subtractive hybridization techniques for identifying differentially expressed and commonly expressed nucleic acid |
| US5837466A (en) * | 1996-12-16 | 1998-11-17 | Vysis, Inc. | Devices and methods for detecting nucleic acid analytes in samples |
| US20020061532A1 (en) * | 1997-02-14 | 2002-05-23 | Mosaic Technologies, Inc. | Method and apparatus for performing amplification of nucleic acids on supports |
| ES2563643T3 (es) * | 1997-04-01 | 2016-03-15 | Illumina Cambridge Limited | Método de secuenciación de ácido nucleico |
| US20020055100A1 (en) * | 1997-04-01 | 2002-05-09 | Kawashima Eric H. | Method of nucleic acid sequencing |
| US6326489B1 (en) * | 1997-08-05 | 2001-12-04 | Howard Hughes Medical Institute | Surface-bound, bimolecular, double-stranded DNA arrays |
| US6087099A (en) * | 1997-09-08 | 2000-07-11 | Myriad Genetics, Inc. | Method for sequencing both strands of a double stranded DNA in a single sequencing reaction |
| US6511803B1 (en) * | 1997-10-10 | 2003-01-28 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US20030022207A1 (en) * | 1998-10-16 | 2003-01-30 | Solexa, Ltd. | Arrayed polynucleotides and their use in genome analysis |
| AR021833A1 (es) * | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| ATE316152T1 (de) * | 1998-10-27 | 2006-02-15 | Affymetrix Inc | Komplexitätsmanagement und analyse genomischer dna |
| US20030108867A1 (en) * | 1999-04-20 | 2003-06-12 | Chee Mark S | Nucleic acid sequencing using microsphere arrays |
| US6300070B1 (en) | 1999-06-04 | 2001-10-09 | Mosaic Technologies, Inc. | Solid phase methods for amplifying multiple nucleic acids |
| US6339147B1 (en) | 1999-07-29 | 2002-01-15 | Epoch Biosciences, Inc. | Attachment of oligonucleotides to solid supports through Schiff base type linkages for capture and detection of nucleic acids |
| DE10051564A1 (de) | 2000-10-18 | 2002-08-01 | Axaron Bioscience Ag | Neue Verfahren zur parallelen Sequenzierung eines Nukleinsäuregemisches an einer Oberfläche |
| ATE317024T1 (de) | 1999-12-29 | 2006-02-15 | Keygene Nv | Verfahren zur erzeugung von oligonukleotiden, im besonderen zur detektion amplifizierter restriktionsfragmente, die durch aflp erhalten wurden |
| AU2001251582A1 (en) | 2000-04-14 | 2001-10-30 | Lynx Therapeutics, Inc. | Method and compositions for ordering restriction fragments |
| AR031640A1 (es) | 2000-12-08 | 2003-09-24 | Applied Research Systems | Amplificacion isotermica de acidos nucleicos en un soporte solido |
| EP1256632A3 (de) | 2001-05-07 | 2004-01-02 | Smithkline Beecham Corporation | Hochdurchsatz-Screening von Polymorphismen |
| EP1472335A4 (de) | 2001-11-08 | 2005-12-28 | Univ Johns Hopkins | Verfahren und systeme zur nukleinsäuresequenzierung |
| GB0205153D0 (en) | 2002-03-05 | 2002-04-17 | Manteia S A | Methods for detecting genome-wide sequence variations associated with a phenotype |
| EP1483404A2 (de) | 2002-03-05 | 2004-12-08 | Solexa Ltd. | Methoden zur detektion genom-überspannender sequenzvariationen, welche mit einem phenotyp assoziiert sind |
| US20040002090A1 (en) * | 2002-03-05 | 2004-01-01 | Pascal Mayer | Methods for detecting genome-wide sequence variations associated with a phenotype |
| US20040126765A1 (en) * | 2002-12-27 | 2004-07-01 | Adams Craig W. | Method and compositions for sequencing nucleic acid molecules |
| ES2338654T5 (es) * | 2003-01-29 | 2017-12-11 | 454 Life Sciences Corporation | Amplificación de ácidos nucleicos en emulsión de perlas |
| EP1592810A2 (de) | 2003-02-12 | 2005-11-09 | Genizon Svenska AB | Verfahren und vorrichtungen zur nukleinsäuresequenzierung |
| GB0324456D0 (en) | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
| WO2005042781A2 (en) | 2003-10-31 | 2005-05-12 | Agencourt Personal Genomics Corporation | Methods for producing a paired tag from a nucleic acid sequence and methods of use thereof |
| GB0400584D0 (en) | 2004-01-12 | 2004-02-11 | Solexa Ltd | Nucleic acid chacterisation |
| GB2412170A (en) | 2004-03-16 | 2005-09-21 | Plant Bioscience Ltd | A method for enriching for target nucleic acids in a sample |
| GB2413796B (en) | 2004-03-25 | 2006-03-29 | Global Genomics Ab | Methods and means for nucleic acid sequencing |
| US20060078899A1 (en) | 2004-10-12 | 2006-04-13 | Scheffer Alicia F | Methods and compositions for reducing label variation in array-based comparative genome hybridization assays |
| DE102004061843A1 (de) | 2004-12-22 | 2006-07-20 | Car Trim Biermann, Marktfort und Dr. Rau GbR (vertretungsberechtigter Gesellschafter: Herr Dr. Friedrich Rau, 08261 Schöneck) | Verfahren und Einrichtung zum Einbringen von Nähten in Textilien, insbesondere in technische Textilien |
| CA2604095A1 (en) | 2005-04-12 | 2006-10-19 | 454 Life Sciences Corporation | Methods for determining sequence variants using ultra-deep sequencing |
| WO2007145612A1 (en) * | 2005-06-06 | 2007-12-21 | 454 Life Sciences Corporation | Paired end sequencing |
| US8428882B2 (en) | 2005-06-14 | 2013-04-23 | Agency For Science, Technology And Research | Method of processing and/or genome mapping of diTag sequences |
| GB0514935D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Methods for sequencing a polynucleotide template |
| GB0514910D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Method for sequencing a polynucleotide template |
| GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
| GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| ATE483804T1 (de) | 2006-01-04 | 2010-10-15 | Si Lok | Verfahren zur zuordnung von nukleinsäuren und zur identifikation fein strukturierter variationen in nukleinsäuren sowie hilfsmittel dafür |
| WO2007091077A1 (en) | 2006-02-08 | 2007-08-16 | Solexa Limited | Method for sequencing a polynucleotide template |
| EP2021503A1 (de) * | 2006-03-17 | 2009-02-11 | Solexa Ltd. | Isothermische methoden zur entstehung von arrays von einzelnen molekülen |
| US20070231823A1 (en) | 2006-03-23 | 2007-10-04 | Mckernan Kevin J | Directed enrichment of genomic DNA for high-throughput sequencing |
| US8921073B2 (en) | 2006-06-23 | 2014-12-30 | Illumina, Inc. | Devices and systems for creation of DNA cluster arrays |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| WO2009032167A1 (en) | 2007-08-29 | 2009-03-12 | Illumina Cambridge | Method for sequencing a polynucleotide template |
-
2005
- 2005-07-20 GB GBGB0514910.9A patent/GB0514910D0/en not_active Ceased
-
2006
- 2006-07-20 EP EP06755782A patent/EP1910560B1/de active Active
- 2006-07-20 US US11/989,172 patent/US8017335B2/en active Active
- 2006-07-20 AT AT06755782T patent/ATE493513T1/de not_active IP Right Cessation
- 2006-07-20 DE DE602006019261T patent/DE602006019261D1/de active Active
- 2006-07-20 WO PCT/GB2006/002690 patent/WO2007010252A1/en active Application Filing
-
2011
- 2011-08-04 US US13/198,527 patent/US8247177B2/en active Active
-
2012
- 2012-07-23 US US13/556,053 patent/US9017945B2/en active Active
-
2015
- 2015-03-31 US US14/674,392 patent/US9297043B2/en active Active
-
2016
- 2016-02-17 US US15/046,053 patent/US9637786B2/en active Active
-
2017
- 2017-05-01 US US15/583,105 patent/US10563256B2/en active Active
-
2019
- 2019-12-26 US US16/727,618 patent/US11781184B2/en active Active
-
2023
- 2023-02-23 US US18/113,216 patent/US20230193384A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US10563256B2 (en) | 2020-02-18 |
| US8247177B2 (en) | 2012-08-21 |
| US9297043B2 (en) | 2016-03-29 |
| US20090181370A1 (en) | 2009-07-16 |
| US8017335B2 (en) | 2011-09-13 |
| US20120053074A1 (en) | 2012-03-01 |
| EP1910560B1 (de) | 2010-12-29 |
| US20230193384A1 (en) | 2023-06-22 |
| US20150203911A1 (en) | 2015-07-23 |
| US9017945B2 (en) | 2015-04-28 |
| US9637786B2 (en) | 2017-05-02 |
| US20160160277A1 (en) | 2016-06-09 |
| WO2007010252A1 (en) | 2007-01-25 |
| US11781184B2 (en) | 2023-10-10 |
| US20170327885A1 (en) | 2017-11-16 |
| US20200216896A1 (en) | 2020-07-09 |
| EP1910560A1 (de) | 2008-04-16 |
| GB0514910D0 (en) | 2005-08-24 |
| US20130171648A1 (en) | 2013-07-04 |
| ATE493513T1 (de) | 2011-01-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602006019261D1 (de) | Verfahren zur sequenzierung einer polynukleotidmatrize | |
| ATE456676T1 (de) | Verfahren zur sequenzierung einer polynukleotidmatrize | |
| SG169356A1 (en) | Method for sequencing a polynucleotide template | |
| WO2008041002A3 (en) | Method for sequencing a polynucleotide template | |
| MX2010012849A (es) | Reactivo de lisis, enlace y/o lavado para aislar y/o purificar acidos nucleicos. | |
| ATE522627T1 (de) | Verfahren zur herstellung von nukleinsäuresonden | |
| DE602007007924D1 (de) | Verfahren zur erhöhung der genauigkeit einer nukleinsäuresequenzierung | |
| EP1845160A4 (de) | Nukleotidsequenz-amplifikationsverfahren | |
| ATE522488T1 (de) | Verfahren zur herstellung von 1,2-dichlorethan | |
| MY149161A (en) | Methods using pores | |
| WO2017201102A8 (en) | Method of improved sequencing by strand identification | |
| DE602005027700D1 (de) | Verfahren zur nukleinsäureimmobilisierung | |
| DE602006009973D1 (de) | Verfahren zur selektiven entfernung von safrol aus muskatöl | |
| ATE465277T1 (de) | Verfahren zur herstellung von leder | |
| ATE456666T1 (de) | Verfahren zur auswertung von ribonukleotidsequenzen | |
| DE602005015590D1 (de) | Verfahren zur durchführung von arbeiten auf einem teil | |
| DE502005003004D1 (de) | Verfahren zur herstellung von polycarbonat | |
| ATE524553T1 (de) | Zusammensetzungen und verfahren, die rna- interferenzen von cdpk-like zur kontrolle von nematoden verwenden | |
| ATE514666T1 (de) | Verfahren zur herstellung von ethen | |
| ATE394369T1 (de) | Verfahren zur aufreinigung von mesotrion | |
| MY184632A (en) | A method of identifying parentage in freshwater prawn macrobrachium rosenbergii | |
| DE502006002680D1 (de) | Verfahren zur herstellung von feinteiligem c.i. pigment red 254 | |
| ATE517863T1 (de) | Verfahren zur herstellung von harnstoff | |
| DE502005003098D1 (de) | Verfahren zur herstellung von polycarbonat | |
| DE502005002108D1 (de) | Verfahren zur funktionalisierung von biosensor-chips |