DE602007011792D1 - Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen - Google Patents

Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen

Info

Publication number
DE602007011792D1
DE602007011792D1 DE602007011792T DE602007011792T DE602007011792D1 DE 602007011792 D1 DE602007011792 D1 DE 602007011792D1 DE 602007011792 T DE602007011792 T DE 602007011792T DE 602007011792 T DE602007011792 T DE 602007011792T DE 602007011792 D1 DE602007011792 D1 DE 602007011792D1
Authority
DE
Germany
Prior art keywords
sugar alcohol
microcrystalline cellulose
auxiliary
tablet formulations
commonly prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007011792T
Other languages
English (en)
Inventor
Jian-Xin Li
Brian Carlin
Thomas Ruszkay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FMC Corp
Original Assignee
FMC Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FMC Corp filed Critical FMC Corp
Publication of DE602007011792D1 publication Critical patent/DE602007011792D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602007011792T 2006-10-27 2007-10-26 Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen Active DE602007011792D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85506606P 2006-10-27 2006-10-27
US85510606P 2006-10-27 2006-10-27
US92816607P 2007-05-08 2007-05-08
PCT/US2007/022685 WO2008057267A2 (en) 2006-10-27 2007-10-26 Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations

Publications (1)

Publication Number Publication Date
DE602007011792D1 true DE602007011792D1 (de) 2011-02-17

Family

ID=39317157

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007011792T Active DE602007011792D1 (de) 2006-10-27 2007-10-26 Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen

Country Status (7)

Country Link
US (3) US8932629B2 (de)
EP (2) EP2076250B1 (de)
JP (2) JP2010507676A (de)
AT (1) ATE493972T1 (de)
DE (1) DE602007011792D1 (de)
TW (2) TW200826976A (de)
WO (2) WO2008057267A2 (de)

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WO2008057266A2 (en) 2008-05-15
JP5410290B2 (ja) 2014-02-05
US20080131505A1 (en) 2008-06-05
WO2008057266A3 (en) 2008-11-13
US20110294904A1 (en) 2011-12-01
ATE493972T1 (de) 2011-01-15
JP2010507677A (ja) 2010-03-11
EP2076250B1 (de) 2011-01-05
EP2076249A2 (de) 2009-07-08
TW200824721A (en) 2008-06-16
WO2008057267A2 (en) 2008-05-15
WO2008057267A3 (en) 2008-07-24
US8932629B2 (en) 2015-01-13
TW200826976A (en) 2008-07-01

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