DE60203265D1 - Stents mit arzneimittelhaltigem amphiphilem polymerüberzug - Google Patents

Stents mit arzneimittelhaltigem amphiphilem polymerüberzug

Info

Publication number
DE60203265D1
DE60203265D1 DE60203265T DE60203265T DE60203265D1 DE 60203265 D1 DE60203265 D1 DE 60203265D1 DE 60203265 T DE60203265 T DE 60203265T DE 60203265 T DE60203265 T DE 60203265T DE 60203265 D1 DE60203265 D1 DE 60203265D1
Authority
DE
Germany
Prior art keywords
amphiphilem
stents
medication
polymer cover
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60203265T
Other languages
English (en)
Other versions
DE60203265T2 (de
Inventor
Lennard Lewis
William Leppard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE60203265D1 publication Critical patent/DE60203265D1/de
Publication of DE60203265T2 publication Critical patent/DE60203265T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43Hormones, e.g. dexamethasone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
DE60203265T 2001-01-11 2002-01-11 Stents mit arzneimittelhaltigem amphiphilem polymerüberzug Expired - Lifetime DE60203265T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0100760.8A GB0100760D0 (en) 2001-01-11 2001-01-11 Drug delivery from stents
GB0100760 2001-01-11
PCT/GB2002/000104 WO2002055122A1 (en) 2001-01-11 2002-01-11 Stens with drug-containing amphiphilic polymer coating

Publications (2)

Publication Number Publication Date
DE60203265D1 true DE60203265D1 (de) 2005-04-21
DE60203265T2 DE60203265T2 (de) 2006-03-30

Family

ID=9906673

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60203265T Expired - Lifetime DE60203265T2 (de) 2001-01-11 2002-01-11 Stents mit arzneimittelhaltigem amphiphilem polymerüberzug

Country Status (8)

Country Link
US (3) US7833544B2 (de)
EP (1) EP1357956B1 (de)
JP (1) JP5192116B2 (de)
AT (1) ATE290895T1 (de)
DE (1) DE60203265T2 (de)
ES (1) ES2239228T3 (de)
GB (1) GB0100760D0 (de)
WO (1) WO2002055122A1 (de)

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060198867A1 (en) * 1997-09-25 2006-09-07 Abbott Laboratories, Inc. Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy
US20030129215A1 (en) * 1998-09-24 2003-07-10 T-Ram, Inc. Medical devices containing rapamycin analogs
US6890546B2 (en) 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US7399480B2 (en) * 1997-09-26 2008-07-15 Abbott Laboratories Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices
US8257726B2 (en) 1997-09-26 2012-09-04 Abbott Laboratories Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices
US8257725B2 (en) 1997-09-26 2012-09-04 Abbott Laboratories Delivery of highly lipophilic agents via medical devices
US8394398B2 (en) 1997-09-26 2013-03-12 Abbott Laboratories Methods of administering rapamycin analogs with anti-inflammatories using medical devices
US8057816B2 (en) * 1997-09-26 2011-11-15 Abbott Laboratories Compositions and methods of administering paclitaxel with other drugs using medical devices
US7357942B2 (en) 1997-09-26 2008-04-15 Abbott Laboratories Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens
US7378105B2 (en) 1997-09-26 2008-05-27 Abbott Laboratories Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens
US8257724B2 (en) 1998-09-24 2012-09-04 Abbott Laboratories Delivery of highly lipophilic agents via medical devices
US20060240070A1 (en) * 1998-09-24 2006-10-26 Cromack Keith R Delivery of highly lipophilic agents via medical devices
US7455853B2 (en) * 1998-09-24 2008-11-25 Abbott Cardiovascular Systems Inc. Medical devices containing rapamycin analogs
US7960405B2 (en) 1998-09-24 2011-06-14 Abbott Laboratories Compounds and methods for treatment and prevention of diseases
DE10107795B4 (de) * 2001-02-13 2014-05-15 Berlex Ag Gefäßstütze mit einem Grundkörper, Verfahren zur Herstellung der Gefäßstütze, Vorrichtung zur Beschichtung der Gefäßstütze
US7727221B2 (en) 2001-06-27 2010-06-01 Cardiac Pacemakers Inc. Method and device for electrochemical formation of therapeutic species in vivo
CA2455766C (en) * 2001-07-31 2011-02-08 Tyco Healthcare Group Lp Bioabsorbable adhesive compounds and compositions
US20080145402A1 (en) * 2001-09-10 2008-06-19 Abbott Cardiovascular Systems Inc. Medical Devices Containing Rapamycin Analogs
US20030220297A1 (en) 2002-02-01 2003-11-27 Berstein David L. Phosphorus-containing compounds and uses thereof
AU2003239175A1 (en) 2002-04-24 2003-11-10 Poly-Med, Inc. Multifaceted endovascular stent coating for preventing restenosis
DE10228078B3 (de) * 2002-06-18 2004-02-26 Innovent E.V. Technologieentwicklung Mittel zur Beschichtung von Implantaten sowie Verfahren zur Beschichtung von Implantaten
WO2004022124A1 (en) * 2002-09-06 2004-03-18 Abbott Laboratories Medical device having hydration inhibitor
WO2004039857A1 (en) * 2002-10-28 2004-05-13 Tyco Healthcare Group Lp Bioabsorbable adhesive compounds
US7144419B2 (en) 2003-01-24 2006-12-05 Medtronic Vascular, Inc. Drug-polymer coated stent with blended phenoxy and styrenic block copolymers
AU2004226327A1 (en) 2003-03-28 2004-10-14 Innovational Holdings, Llc Implantable medical device with beneficial agent concentration gradient
JP4732346B2 (ja) * 2003-08-19 2011-07-27 バイエル・マテリアルサイエンス・アクチェンゲゼルシャフト 医療機器用の高分子薬剤溶出システム
US7488343B2 (en) * 2003-09-16 2009-02-10 Boston Scientific Scimed, Inc. Medical devices
US8309112B2 (en) 2003-12-24 2012-11-13 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same
US7846201B2 (en) * 2004-02-20 2010-12-07 The Children's Hospital Of Philadelphia Magnetically-driven biodegradable gene delivery nanoparticles formulated with surface-attached polycationic complex
US9028829B2 (en) * 2004-02-20 2015-05-12 The Children's Hospital Of Philadelphia Uniform field magnetization and targeting of therapeutic formulations
US8562505B2 (en) * 2004-02-20 2013-10-22 The Children's Hospital Of Philadelphia Uniform field magnetization and targeting of therapeutic formulations
US8137397B2 (en) * 2004-02-26 2012-03-20 Boston Scientific Scimed, Inc. Medical devices
US20100030183A1 (en) * 2004-03-19 2010-02-04 Toner John L Method of treating vascular disease at a bifurcated vessel using a coated balloon
ATE534424T1 (de) * 2004-03-19 2011-12-15 Abbott Lab Mehrfache arzneiabgabe aus einem ballon und eine prothese
US20070027523A1 (en) * 2004-03-19 2007-02-01 Toner John L Method of treating vascular disease at a bifurcated vessel using coated balloon
US8431145B2 (en) 2004-03-19 2013-04-30 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis
US7758892B1 (en) * 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US8119153B2 (en) 2004-08-26 2012-02-21 Boston Scientific Scimed, Inc. Stents with drug eluting coatings
WO2006026725A2 (en) 2004-08-31 2006-03-09 C.R. Bard, Inc. Self-sealing ptfe graft with kink resistance
DE102004046244A1 (de) * 2004-09-22 2006-03-30 Orlowski, Michael, Dr. Beschichtetes Coronarstentsystem
US9011831B2 (en) 2004-09-30 2015-04-21 Advanced Cardiovascular Systems, Inc. Methacrylate copolymers for medical devices
US20060134168A1 (en) 2004-12-07 2006-06-22 Chappa Ralph A Coatings with crystallized active agent(s) and methods
AU2006213822B2 (en) 2005-02-09 2011-05-26 Covidien Lp Synthetic sealants
WO2007032777A2 (en) 2005-03-23 2007-03-22 Abbott Laboratories Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy
EP2327429B1 (de) * 2005-03-23 2014-09-17 Abbott Laboratories Verabreichung stark lipophiler wirkstoffe mittels medizinischer vorrichtungen
DE102005015128B4 (de) * 2005-03-31 2008-12-11 Bayer Schering Pharma Aktiengesellschaft Wafer enthaltend Steroidhormone
US20060240060A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060240253A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Guidewire and tube with lubricious coating
US20060241000A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060240059A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious eluting polymer blend and coating made from the same
US20100100124A1 (en) * 2005-05-05 2010-04-22 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US8044234B2 (en) * 2005-05-05 2011-10-25 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US20090177226A1 (en) * 2005-05-05 2009-07-09 Jon Reinprecht Bioabsorbable Surgical Compositions
US20100016888A1 (en) * 2005-05-05 2010-01-21 Allison Calabrese Surgical Gasket
CA2611119A1 (en) * 2005-06-08 2006-12-14 C.R. Bard Inc. Grafts and stents having inorganic bio-compatible calcium salt
CA2610896C (en) 2005-06-17 2014-07-08 C.R. Bard, Inc. Vascular graft with kink resistance after clamping
US20070009564A1 (en) * 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
KR101492545B1 (ko) 2005-07-15 2015-02-12 미셀 테크놀로지즈, 인코포레이티드 제어된 형태의 약물 분말을 함유하는 중합체 코팅
AU2011256902B2 (en) * 2005-07-15 2015-03-12 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
CA2615452C (en) * 2005-07-15 2015-03-31 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
US20090062909A1 (en) * 2005-07-15 2009-03-05 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
JP5118042B2 (ja) * 2005-09-06 2013-01-16 シー・アール・バード・インコーポレーテッド 薬物結晶を含有する移植用インプラント
DE102005051587A1 (de) * 2005-10-27 2007-05-03 Consortium für elektrochemische Industrie GmbH Zwitterionische Strukturelemente aufweisende Partikel
JP5280852B2 (ja) 2005-11-09 2013-09-04 シー・アール・バード・インコーポレーテッド 放射線不透過性マーカーを有する移植片及びステント植皮
US7715922B1 (en) 2005-11-16 2010-05-11 Pacesetter, Inc. Polyethylene oxide and polyisobutylene copolymers and their usage on medical devices
US7708774B1 (en) 2005-11-16 2010-05-04 Pacesetter, Inc. Polyethylene oxide and silicone copolymers and their usage on medical devices
US7553546B1 (en) 2005-11-16 2009-06-30 Pacesetter, Inc. Polyethylene oxide and silicone copolymers and their usage on medical devices
US20070116736A1 (en) * 2005-11-23 2007-05-24 Argentieri Dennis C Local vascular delivery of PI3 kinase inhibitors alone or in combination with sirolimus to prevent restinosis following vascular injury
AU2006321912B2 (en) * 2005-12-06 2012-07-12 Covidien Lp Carbodiimide crosslinking of functionalized polethylene glycols
EP1960469B1 (de) * 2005-12-06 2016-07-13 Covidien LP Biologisch absorbierbare verbindungen und diese enthaltende zusammensetzungen
AU2006321911B2 (en) * 2005-12-06 2012-05-17 Covidien Lp Biocompatible surgical compositions
JP2009518129A (ja) * 2005-12-06 2009-05-07 タイコ ヘルスケア グループ リミテッド パートナーシップ 生体吸収性外科用組成物
JP5088894B2 (ja) * 2005-12-06 2012-12-05 タイコ ヘルスケア グループ リミテッド パートナーシップ 生体適合性組織封止剤および接着剤
US7795326B2 (en) * 2005-12-07 2010-09-14 Rochal Industries, Llp Conformable bandage and coating material
JP2009518138A (ja) * 2005-12-08 2009-05-07 タイコ ヘルスケア グループ リミテッド パートナーシップ 生体適合性外科用組成物
US8449714B2 (en) * 2005-12-08 2013-05-28 Covidien Lp Biocompatible surgical compositions
CA2629932C (en) * 2005-12-08 2014-07-08 Tyco Healthcare Group Lp Viscosity-reduced sprayable compositions
US8840660B2 (en) * 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
CA2573472A1 (en) * 2006-01-23 2007-07-23 Tyco Healthcare Group Lp Biodegradable hemostatic compositions
US8089029B2 (en) * 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
AU2007221315B2 (en) 2006-02-22 2013-03-14 Covidien Lp Biodegradable phosphoester polyamines
US20070224244A1 (en) * 2006-03-22 2007-09-27 Jan Weber Corrosion resistant coatings for biodegradable metallic implants
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
CA2996768C (en) 2006-04-26 2020-12-08 Micell Technologies, Inc. Coatings containing multiple drugs
US20080004694A1 (en) * 2006-05-23 2008-01-03 Abbott Laboratories Compositions and methods for administering dexamethasone which promote human coronary artery endothelial cell migration
WO2007146680A1 (en) * 2006-06-06 2007-12-21 Florida State University Research Foundation , Inc. Stabilized silica colloid
JP2009545407A (ja) * 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド,インコーポレイテッド 三次元分解制御を備えたエンドプロテーゼ
US20080057104A1 (en) * 2006-09-01 2008-03-06 Joseph Walker Matrix metalloproteinase inhibitor delivering devices
WO2008034047A2 (en) * 2006-09-15 2008-03-20 Boston Scientific Limited Endoprosthesis with adjustable surface features
WO2008034013A2 (en) * 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
JP2010503489A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生体内分解性内部人工器官およびその製造方法
DE602007011114D1 (de) * 2006-09-15 2011-01-20 Boston Scient Scimed Inc Biologisch erodierbare endoprothese mit biostabilen anorganischen schichten
WO2008034066A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
WO2008036548A2 (en) 2006-09-18 2008-03-27 Boston Scientific Limited Endoprostheses
WO2008042909A2 (en) * 2006-10-02 2008-04-10 Micell Technologies Inc. Surgical sutures having increased strength
EP2079575B1 (de) 2006-10-12 2021-06-02 C.R. Bard, Inc. Herstellungsverfahren für gefässtransplantate mit mehreren kanälen
US20080097577A1 (en) * 2006-10-20 2008-04-24 Boston Scientific Scimed, Inc. Medical device hydrogen surface treatment by electrochemical reduction
CA2667228C (en) * 2006-10-23 2015-07-14 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
EP2092941A3 (de) * 2006-11-20 2009-11-18 Lutonix, Inc. Wirkstofffreisetzende Beschichtungen für medizinische Vorrichtungen
ES2506144T3 (es) * 2006-12-28 2014-10-13 Boston Scientific Limited Endoprótesis bioerosionables y procedimiento de fabricación de las mismas
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
CA2679712C (en) 2007-01-08 2016-11-15 Micell Technologies, Inc. Stents having biodegradable layers
CA2684482C (en) * 2007-04-17 2014-08-12 Micell Technologies, Inc. Stents having biodegradable layers
US7673379B1 (en) 2007-05-11 2010-03-09 Abbott Cardiovascular Systems Inc. Method of producing a stent-balloon assembly
US20110123476A1 (en) * 2007-05-24 2011-05-26 Mbiya Kapiamba Adhesive Formulations
AU2008256684B2 (en) 2007-05-25 2012-06-14 Micell Technologies, Inc. Polymer films for medical device coating
US7858835B2 (en) * 2007-06-27 2010-12-28 Tyco Healthcare Group Lp Foam control for synthetic adhesive/sealant
US8052745B2 (en) * 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
JP2011500916A (ja) * 2007-10-17 2011-01-06 エージェンシー フォー サイエンス, テクノロジー アンド リサーチ 親水性と疎水性のバランスがとれた水溶性蛍光物質
WO2009051780A1 (en) * 2007-10-19 2009-04-23 Micell Technologies, Inc. Drug coated stents
US8500947B2 (en) 2007-11-15 2013-08-06 Covidien Lp Speeding cure rate of bioadhesives
US9533006B2 (en) 2007-11-19 2017-01-03 University Of Washington Marine coatings
US20090143855A1 (en) * 2007-11-29 2009-06-04 Boston Scientific Scimed, Inc. Medical Device Including Drug-Loaded Fibers
WO2009079389A2 (en) * 2007-12-14 2009-06-25 Boston Scientific Limited Drug-eluting endoprosthesis
JP5601591B2 (ja) * 2008-04-09 2014-10-08 リューベン,アレクサンダー バルーンカテーテルのバルーン上の生体活性表面の製造方法及び前記方法で作られた生体活性表面を備えるバルーン
EP2271294B1 (de) * 2008-04-17 2018-03-28 Micell Technologies, Inc. Stents mit biologisch abbaubaren schichten
US7998192B2 (en) * 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8202529B2 (en) * 2008-05-30 2012-06-19 Abbott Cardiovascular Systems Inc. Implantable drug delivery devices having alternating hydrophilic and amphiphilic polymer layers
US8986728B2 (en) 2008-05-30 2015-03-24 Abbott Cardiovascular Systems Inc. Soluble implantable device comprising polyelectrolyte with hydrophobic counterions
US8236046B2 (en) * 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
JP2011528275A (ja) 2008-07-17 2011-11-17 ミセル テクノロジーズ,インク. 薬物送達医療デバイス
US7985252B2 (en) * 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8114429B2 (en) 2008-09-15 2012-02-14 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8257722B2 (en) 2008-09-15 2012-09-04 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8128951B2 (en) 2008-09-15 2012-03-06 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US9198968B2 (en) 2008-09-15 2015-12-01 The Spectranetics Corporation Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8382824B2 (en) * 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8834913B2 (en) * 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
EP2403546A2 (de) * 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Selbstpufferende medizinische implantate
US20100239635A1 (en) * 2009-03-23 2010-09-23 Micell Technologies, Inc. Drug delivery medical device
CA2756307C (en) * 2009-03-23 2017-08-08 Micell Technologies, Inc. Peripheral stents having layers and reinforcement fibers
CN102481195B (zh) 2009-04-01 2015-03-25 米歇尔技术公司 涂覆支架
CA2757455C (en) * 2009-04-03 2017-08-22 Ashland Licensing And Intellectual Property Llc Ultraviolet radiation curable pressure sensitive acrylic adhesive
WO2010121187A2 (en) 2009-04-17 2010-10-21 Micell Techologies, Inc. Stents having controlled elution
EP2453834A4 (de) 2009-07-16 2014-04-16 Micell Technologies Inc Medizinische wirkstofffreisetzungsvorrichtung
US20110022158A1 (en) * 2009-07-22 2011-01-27 Boston Scientific Scimed, Inc. Bioerodible Medical Implants
WO2011057224A2 (en) 2009-11-06 2011-05-12 University Of Washington Through Its Center For Commercialization Zwitterionic polymer bioconjugates and related methods
US20110144577A1 (en) * 2009-12-11 2011-06-16 John Stankus Hydrophilic coatings with tunable composition for drug coated balloon
US8480620B2 (en) * 2009-12-11 2013-07-09 Abbott Cardiovascular Systems Inc. Coatings with tunable solubility profile for drug-coated balloon
US8951595B2 (en) 2009-12-11 2015-02-10 Abbott Cardiovascular Systems Inc. Coatings with tunable molecular architecture for drug-coated balloon
US11369498B2 (en) 2010-02-02 2022-06-28 MT Acquisition Holdings LLC Stent and stent delivery system with improved deliverability
US8668732B2 (en) * 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
WO2011133655A1 (en) 2010-04-22 2011-10-27 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
CA2805631C (en) 2010-07-16 2018-07-31 Micell Technologies, Inc. Drug delivery medical device
WO2012166819A1 (en) 2011-05-31 2012-12-06 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
CA2841360A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
WO2013156871A2 (en) 2012-04-17 2013-10-24 University College Dublin, National University Of Ireland, Dublin Thromboxane receptor antagonists
WO2013156861A2 (en) 2012-04-17 2013-10-24 University College Dublin, National University Of Ireland, Dublin Methods and compounds for treating proliferative disorders and viral infections
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
EP2737894A1 (de) 2012-12-03 2014-06-04 Debiotech S.A. Intelligente Beschichtung für implantierbare Vorrichtungen
US9808560B2 (en) 2013-03-01 2017-11-07 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable, non-thrombogenic elastomeric polyurethanes
KR20150143476A (ko) 2013-03-12 2015-12-23 미셀 테크놀로지즈, 인코포레이티드 생흡수성 생체의학적 임플란트
US9545301B2 (en) 2013-03-15 2017-01-17 Covidien Lp Coated medical devices and methods of making and using same
US9872940B2 (en) 2013-04-01 2018-01-23 Terumo Kabushiki Kaisha Drug coating layer
KR102079613B1 (ko) 2013-05-15 2020-02-20 미셀 테크놀로지즈, 인코포레이티드 생흡수성 생체의학적 임플란트
US10597540B2 (en) * 2013-05-27 2020-03-24 Jsr Corporation Surface treatment agent for surface configured from inorganic material, tool and device having modified surface, and method for manufacturing tool and device
US9668890B2 (en) 2013-11-22 2017-06-06 Covidien Lp Anti-thrombogenic medical devices and methods
US10525171B2 (en) 2014-01-24 2020-01-07 The Spectranetics Corporation Coatings for medical devices
JP6008213B2 (ja) * 2014-08-06 2016-10-19 リューベン,アレクサンダー 体内プロテーゼ上又はバルーンカテーテルのバルーン上の生体活性表面の製造方法
CA2989271C (en) 2015-06-16 2023-09-26 University College Dublin, National University Of Ireland, Dublin Thromboxane receptor antagonists
JP7158993B2 (ja) * 2018-10-15 2022-10-24 千秋 東 ホスホリルコリン基含有共重合体、および生体用医療基材
CN112933301B (zh) * 2019-11-26 2023-01-24 上海微创医疗器械(集团)有限公司 载药植入医疗器械及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU666485B2 (en) 1991-07-05 1996-02-15 Biocompatibles Uk Limited Polymeric surface coatings
GB9301701D0 (en) 1993-01-28 1993-03-17 Biocompatibles Ltd New zwitterionic materials
WO1994021308A1 (en) * 1993-03-18 1994-09-29 Cedars-Sinai Medical Center Drug incorporating and releasing polymeric coating for bioprosthesis
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
CN100998869A (zh) 1993-07-19 2007-07-18 血管技术药物公司 抗血管生长组合物及使用方法
GB9317178D0 (en) * 1993-08-18 1993-10-06 Biocompatibles Ltd Polymer surface coatings
US5380299A (en) * 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
AU5566698A (en) 1997-01-10 1998-08-03 Biocompatibles Limited Polymers
EP1019034A2 (de) 1997-07-01 2000-07-19 Atherogenics, Inc. Verbesserung antioxidativer therapie für hyperproliferative zustanden
AU8782098A (en) * 1997-08-13 1999-03-08 Boston Scientific Limited Loading and release of water-insoluble drugs
AU3759100A (en) 1999-03-24 2000-10-09 B.F. Goodrich Company, The Inhibition of matrix metalloproteinases with polymers and pharmaceutical applications thereof
US6872225B1 (en) * 1999-05-27 2005-03-29 Biocompatibles Uk Limited Local drug delivery

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US7833544B2 (en) 2010-11-16
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US20110034995A1 (en) 2011-02-10
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US20110034994A1 (en) 2011-02-10
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JP2004529674A (ja) 2004-09-30
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