DE60213815D1 - Elektronische karte für die transdermale arzneimittelabgabe und analytenextraktion - Google Patents

Elektronische karte für die transdermale arzneimittelabgabe und analytenextraktion

Info

Publication number
DE60213815D1
DE60213815D1 DE60213815T DE60213815T DE60213815D1 DE 60213815 D1 DE60213815 D1 DE 60213815D1 DE 60213815 T DE60213815 T DE 60213815T DE 60213815 T DE60213815 T DE 60213815T DE 60213815 D1 DE60213815 D1 DE 60213815D1
Authority
DE
Germany
Prior art keywords
skin
substance
drug delivery
sites
electronic card
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60213815T
Other languages
English (en)
Inventor
Zohar Avrahami
Yossi Gross
Ze Ev Sohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TransPharma Ltd
Original Assignee
TransPharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TransPharma Ltd filed Critical TransPharma Ltd
Application granted granted Critical
Publication of DE60213815D1 publication Critical patent/DE60213815D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
DE60213815T 2001-05-17 2002-05-15 Elektronische karte für die transdermale arzneimittelabgabe und analytenextraktion Expired - Lifetime DE60213815D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/859,646 US6597946B2 (en) 1998-11-09 2001-05-17 Electronic card for transdermal drug delivery and analyte extraction
PCT/IL2002/000376 WO2002092163A2 (en) 2001-05-17 2002-05-15 Electronic card for transdermal drug delivery and analyte extraction

Publications (1)

Publication Number Publication Date
DE60213815D1 true DE60213815D1 (de) 2006-09-21

Family

ID=25331407

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60213815T Expired - Lifetime DE60213815D1 (de) 2001-05-17 2002-05-15 Elektronische karte für die transdermale arzneimittelabgabe und analytenextraktion

Country Status (5)

Country Link
US (2) US6597946B2 (de)
EP (1) EP1404406B1 (de)
AT (1) ATE335523T1 (de)
DE (1) DE60213815D1 (de)
WO (1) WO2002092163A2 (de)

Families Citing this family (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6024089A (en) 1997-03-14 2000-02-15 Nelcor Puritan Bennett Incorporated System and method for setting and displaying ventilator alarms
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
CA2478614C (en) * 2001-03-13 2013-01-15 University Of South Florida Electromanipulation device and method
US20030139731A1 (en) * 2002-01-23 2003-07-24 Kevin Marchitto Device for transcutaneous drug delivery and uses therefor
WO2003074102A2 (en) * 2002-03-04 2003-09-12 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
AU2003220143A1 (en) * 2002-03-11 2003-09-29 Altea Therapeutics Corporation Transdermal integrated actuator device, methods of making and using same
WO2003089043A2 (en) * 2002-04-19 2003-10-30 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US7569393B2 (en) 2002-06-28 2009-08-04 International Technidyne Corporation Analytical test cartridge; and, methods
US6794877B2 (en) * 2002-07-31 2004-09-21 International Technidyne Corporation Apparatus and method for analytical determinations
US7383084B2 (en) * 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
IL152574A (en) 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
US7662404B2 (en) * 2002-10-31 2010-02-16 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
US8133505B2 (en) * 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
JP2006504476A (ja) * 2002-11-05 2006-02-09 エム２・メディカル・アクティーゼルスカブ 使い捨て、着用式インシュリン投与装置、前記装置とプログラム制御装置の組合せ、及び前記装置の操作制御方法
TW200417929A (en) * 2002-12-10 2004-09-16 Nissha Printing Narrow frame type touch panel
US7031769B2 (en) * 2003-02-21 2006-04-18 Birch Point Medical, Inc. Dosage control electrode for iontophoresis device
JP5015594B2 (ja) * 2003-06-23 2012-08-29 トランスファーマ メディカル リミテッド 化粧剤用経皮送達システム
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US7882750B2 (en) * 2003-08-01 2011-02-08 Cidra Corporate Services, Inc. Method and apparatus for measuring parameters of a fluid flowing within a pipe using a configurable array of sensors
WO2005012843A2 (en) * 2003-08-01 2005-02-10 Cidra Corporation Method and apparatus for measuring parameters of a fluid flowing within a pipe using a configurable array of sensors
IL159273A0 (en) * 2003-12-09 2004-06-01 Transpharma Medical Ltd Transdermal delivery system for sustained release of polypeptides
IL160033A0 (en) * 2004-01-25 2004-06-20 Transpharma Medical Ltd Transdermal delivery system for polynucleotides
JP5065005B2 (ja) * 2004-04-01 2012-10-31 ザ ジェネラル ホスピタル コーポレイション 皮膚科治療及び組織再形成のための方法及び装置
US20050226921A1 (en) * 2004-04-13 2005-10-13 Kortzebom Robert N Non-invasive analysis and controlled dosage transdermal active patch
US7206630B1 (en) * 2004-06-29 2007-04-17 Cleveland Medical Devices, Inc Electrode patch and wireless physiological measurement system and method
US20070292445A1 (en) * 2004-07-06 2007-12-20 Transpharma Medical Ltd. Delivery system for transdermal immunization
US20060047281A1 (en) * 2004-09-01 2006-03-02 Syneron Medical Ltd. Method and system for invasive skin treatment
JP2008520331A (ja) * 2004-11-18 2008-06-19 トランスファーマ メディカル リミテッド 薬剤の経皮的送達のためのマイクロチャネル形成とイオントフォレーシスの組合せ
WO2006063063A2 (en) * 2004-12-09 2006-06-15 Flexible Medical Systems, Llc Apparatus and method for continuous real-time trace biomolecular sampling, analysis and delivery
US10130801B1 (en) * 2005-02-07 2018-11-20 Ipventure, Inc. Electronic transdermal chemical delivery
US20060264804A1 (en) * 2005-04-07 2006-11-23 Yoram Karmon Device and kit for delivery of encapsulated substances and methods of use thereof
WO2006111201A1 (en) 2005-04-18 2006-10-26 Pantec Biosolutions Ag Laser microporator
US7856263B2 (en) * 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
US20080274166A1 (en) * 2005-06-10 2008-11-06 Transpharma Medical Ltd. Patch for Transdermal Drug Delivery
TWI419717B (zh) * 2005-06-17 2013-12-21 Altea Therapeutics Corp 滲透傳送系統及其使用方法
US20070009542A1 (en) * 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US8295922B2 (en) * 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
RU2008114490A (ru) 2005-09-15 2009-10-20 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Устройство ионтофореза стержневого типа
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070066934A1 (en) * 2005-09-19 2007-03-22 Transport Pharmaceuticals, Inc. Electrokinetic delivery system and methods therefor
US20070260171A1 (en) * 2005-09-27 2007-11-08 Higuchi John W Intraocular iontophoretic device and associated methods
US8755880B2 (en) * 2005-10-24 2014-06-17 Aciont, Inc. Intraocular iontophoretic device and associated methods
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
WO2007038555A1 (en) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
US20070078502A1 (en) * 2005-10-05 2007-04-05 Thermage, Inc. Method and apparatus for estimating a local impedance factor
EP1945193A1 (de) * 2005-10-06 2008-07-23 Pantec Biosolutions AG Transdermales abgabesystem zur behandlung von unfruchtbarkeit
US7957815B2 (en) * 2005-10-11 2011-06-07 Thermage, Inc. Electrode assembly and handpiece with adjustable system impedance, and methods of operating an energy-based medical system to treat tissue
US8702691B2 (en) * 2005-10-19 2014-04-22 Thermage, Inc. Treatment apparatus and methods for delivering energy at multiple selectable depths in tissue
US8634907B2 (en) * 2005-10-24 2014-01-21 Aciont, Inc. Intraocular iontophoretic device and associated methods
US8333874B2 (en) * 2005-12-09 2012-12-18 Flexible Medical Systems, Llc Flexible apparatus and method for monitoring and delivery
WO2007079189A2 (en) * 2005-12-30 2007-07-12 Tti Ellebeau, Inc. System and method for remote based control of an iontophoresis device
ITMI20060306A1 (it) * 2006-02-20 2007-08-21 Bc System S R L Sistema e metodo per la somministrazione di una composizione cosmetica ad un soggetto
US8021310B2 (en) 2006-04-21 2011-09-20 Nellcor Puritan Bennett Llc Work of breathing display for a ventilation system
EP2010276B1 (de) * 2006-04-26 2014-01-22 Covidien LP Mehrfachmodus-mikroporationsvorrichtung
US8246611B2 (en) 2006-06-14 2012-08-21 Candela Corporation Treatment of skin by spatial modulation of thermal heating
US20080077076A1 (en) * 2006-08-29 2008-03-27 Transcutaneous Technologies Inc. Iontophoresis device and method for operation with a usb (universal serial bus) power source
US7784461B2 (en) 2006-09-26 2010-08-31 Nellcor Puritan Bennett Llc Three-dimensional waveform display for a breathing assistance system
KR100730582B1 (ko) * 2006-11-20 2007-06-20 아람휴비스(주) 이온토포레시스 장치
EP2061551A2 (de) * 2006-12-01 2009-05-27 TTI ellebeau, Inc. Systeme, vorrichtungen und verfahren zum antrieb oder zur steuerung von geräten, z. b. geräten zur transdermalen verabreichung
EP2674188B1 (de) * 2007-01-22 2017-03-01 Nitto Denko Corporation Transdermales System zur Abgabe von Permeanten
WO2008091983A2 (en) * 2007-01-25 2008-07-31 Thermage, Inc. Treatment apparatus and methods for inducing microburn patterns in tissue
EP1964512A3 (de) 2007-02-28 2008-10-29 Sysmex Corporation Verfahren zur Messung des Leitwerts der Haut, Verfahren zur Analyse der Komponentenkonzentration, Gerät zur Messung des Leitwerts der Haut und Vorrichtung zur Analyse der Komponentenkonzentration
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
WO2008114220A2 (en) * 2007-03-19 2008-09-25 Insuline Medical Ltd. Device for drug delivery and associated connections thereto
US9220837B2 (en) * 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
CN104069567A (zh) * 2007-03-19 2014-10-01 茵苏莱恩医药有限公司 药物输送设备
US20080269735A1 (en) * 2007-04-26 2008-10-30 Agustina Vila Echague Optical array for treating biological tissue
JP2010529897A (ja) * 2007-06-15 2010-09-02 ニトリツク・バイオ・セラピユーテイクス・インコーポレーテツド 動電学的薬剤配送の電流集中緩和方法とシステム
WO2008157485A1 (en) * 2007-06-15 2008-12-24 Transport Pharmaceuticals, Inc. Current concentration system and method for electrokinetic delivery of medicaments
US20080319371A1 (en) * 2007-06-19 2008-12-25 Transport Pharmaceuticals, Inc. Method and system for treating of onychomycosis with an applicator having a gel medicament layer
WO2009009661A1 (en) * 2007-07-10 2009-01-15 Thermage, Inc. Treatment apparatus and methods for delivering high frequency energy across large tissue areas
JP2010536434A (ja) * 2007-08-17 2010-12-02 イシス バイオポリマー エルエルシー イオン泳動薬物送達システム
WO2009047774A2 (en) * 2007-10-09 2009-04-16 Transpharma Ltd. Magnetic patch coupling
JP5612474B2 (ja) * 2007-10-17 2014-10-22 トランスファーマ メディカル リミテッド 溶出速度の検証
CA2704164A1 (en) * 2007-10-29 2009-05-07 Transpharma Medical Ltd. Vertical patch drying
CN101969873B (zh) 2007-12-05 2015-05-13 赛诺龙医疗公司 一次性电磁能施用器以及使用它的方法
CA2708497A1 (en) * 2007-12-10 2009-06-18 Isis Biopolymer Llc Iontophoretic drug delivery device and software application
EP2231229A1 (de) 2007-12-18 2010-09-29 Insuline Medical Ltd. Wirkstofffreisetzungsvorrichtung mit sensor für geschlossenen kreislauf
AU2009205297A1 (en) 2008-01-17 2009-07-23 Syneron Medical Ltd. A hair removal apparatus for personal use and the method of using same
US8862223B2 (en) * 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US20110160640A1 (en) * 2008-01-18 2011-06-30 Yanaki Jamal S Operation management of active transdermal medicament patch
EP2237732A4 (de) 2008-01-24 2011-06-01 Syneron Medical Ltd Vorrichtung, apparatur und verfahren zur fettgewebebehandlung
EP2082777A1 (de) * 2008-01-27 2009-07-29 Oncotherm Kft. Flexible, poröse, großflächige Elektrode zum Heizen
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
BRPI0913924B1 (pt) 2008-07-01 2020-02-04 Univ Leland Stanford Junior método para determinação da probabilidade de que um indivíduo do sexo feminino irá experimentar um evento de nascimento com vida
EP2153866A1 (de) * 2008-08-14 2010-02-17 Oncotherm Kft. Tragbare Funkfrequenz-Hyperthermie-Vorrichtung mit flexibler Behandlungselektrode für elektrisch kapazitiv gekoppelte Energieübertragung
WO2010029552A1 (en) * 2008-09-10 2010-03-18 Transpharma Medical Ltd. Transdermal delivery of oligosaccharides
ES2412783T3 (es) 2008-09-21 2013-07-12 Syneron Medical Ltd. Un método y aparato para el tratamiento personal de la piel
CA2733265A1 (en) * 2008-09-30 2010-04-08 Teikoku Pharma Usa, Inc. Transdermal extended-delivery donepezil compositions and methods for using the same
US9801575B2 (en) 2011-04-15 2017-10-31 Dexcom, Inc. Advanced analyte sensor calibration and error detection
EP2355758A2 (de) 2008-11-07 2011-08-17 Insuline Medical Ltd. Arzneimittelabgabevorrichtung und -verfahren
US8357150B2 (en) 2009-07-20 2013-01-22 Syneron Medical Ltd. Method and apparatus for fractional skin treatment
US8948838B2 (en) * 2009-01-27 2015-02-03 Scibase Ab Switch probe for multiple electrode measurement of impedance
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
CA2655017A1 (en) 2009-02-20 2010-08-20 Abdeltif Essalik Non-invasive biomedical detection and monitoring systems
EP2730313A1 (de) 2009-02-25 2014-05-14 Syneron Medical Ltd. Elektrische Hautverjüngung
US20110092881A1 (en) * 2009-05-08 2011-04-21 Isis Biopolymer Inc. Iontophoretic device with contact sensor
WO2010129928A1 (en) * 2009-05-08 2010-11-11 Isis Biopolymer Llc Iontophoretic device with improved counterelectrode
US8924878B2 (en) 2009-12-04 2014-12-30 Covidien Lp Display and access to settings on a ventilator graphical user interface
DE102009056746A1 (de) * 2009-12-04 2011-06-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung von Peptiden
DE102009056745A1 (de) 2009-12-04 2011-06-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung von Peptiden
US9119925B2 (en) 2009-12-04 2015-09-01 Covidien Lp Quick initiation of respiratory support via a ventilator user interface
US8335992B2 (en) 2009-12-04 2012-12-18 Nellcor Puritan Bennett Llc Visual indication of settings changes on a ventilator graphical user interface
US9262588B2 (en) 2009-12-18 2016-02-16 Covidien Lp Display of respiratory data graphs on a ventilator graphical user interface
US8499252B2 (en) 2009-12-18 2013-07-30 Covidien Lp Display of respiratory data graphs on a ventilator graphical user interface
US20100178307A1 (en) * 2010-01-13 2010-07-15 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
US11660392B2 (en) * 2010-02-05 2023-05-30 Deka Products Limited Partnership Devices, methods and systems for wireless control of medical devices
CN102947857A (zh) 2010-06-20 2013-02-27 尤尼维公司 决策支持系统（dss）和电子健康记录（ehr）
EP2593788A4 (de) 2010-07-13 2016-08-10 Univfy Inc Verfahren zur risikobewertung von mehrlingsgeburten bei der behandlung von unfruchtbarkeit
US9877673B2 (en) 2010-12-10 2018-01-30 Clinitech, Llc Transdermal sampling and analysis device
US9451913B2 (en) 2010-12-10 2016-09-27 Touchtek Labs, Llc Transdermal sampling and analysis device
ITTO20110794A1 (it) * 2011-09-06 2013-03-07 Tss Medical Lab S R L Dispositivo autonomo, portatile per terapia elettromagnetica del dolore
US9934361B2 (en) 2011-09-30 2018-04-03 Univfy Inc. Method for generating healthcare-related validated prediction models from multiple sources
EP2773415B1 (de) * 2011-11-01 2016-12-14 Lumenis Ltd. Vorrichtung für eine druckverstärkte fraktionierte behandlung und arzneimittelabgabe
US8702683B2 (en) * 2011-11-08 2014-04-22 Elwha Llc Systems and methods for dynamic drug therapy response to blood pressure incidents
US8753284B2 (en) 2011-11-08 2014-06-17 Elwha, Llc Blood pressure cuff
US9968284B2 (en) 2011-12-02 2018-05-15 Clinitech, Llc Anti-interferent barrier layers for non-invasive transdermal sampling and analysis device
US9433376B2 (en) 2012-03-16 2016-09-06 Dexcom, Inc. Systems and methods for processing analyte sensor data
SI2827710T1 (sl) 2012-03-19 2020-04-30 Cidara Therapeutics, Inc. Režimi odmerjanja za spojine razreda ehinokandin
EP2838460A1 (de) * 2012-04-16 2015-02-25 Koninklijke Philips N.V. Verfahren und system zur hautbehandlung
US10362967B2 (en) 2012-07-09 2019-07-30 Covidien Lp Systems and methods for missed breath detection and indication
KR101979746B1 (ko) 2012-09-13 2019-05-17 (주)아모레퍼시픽 전기 천공 장치
JP5580383B2 (ja) * 2012-10-05 2014-08-27 株式会社 資生堂 美容機器及び通電方法及び記録媒体
FR3016296B1 (fr) * 2014-01-14 2021-06-25 Feeligreen Dispositif pour l'electrostimulation et/ou l'iontophorese
FR3020958B1 (fr) * 2014-05-19 2016-06-24 Commissariat Energie Atomique Dispositif d'electrode cutanee et dispositif d'electrostimulation integrant ce dispositif d'electrode.
US9950129B2 (en) 2014-10-27 2018-04-24 Covidien Lp Ventilation triggering using change-point detection
CN105224774B (zh) * 2015-11-11 2018-01-30 广东电网有限责任公司电力调度控制中心 电力系统运行状态仿真方法及系统
IT201700014315A1 (it) * 2017-02-09 2018-08-09 Bruno Massimo Cetroni Dispositivo per il trasporto intracellulare in biorisonanza
US20190120785A1 (en) 2017-10-24 2019-04-25 Dexcom, Inc. Pre-connected analyte sensors
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
UA130806U (uk) * 2018-06-14 2018-12-26 Микола Григорович Ляпко Аплікатор для рефлексотерапії
US11633129B2 (en) 2019-04-05 2023-04-25 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating redox cofactors
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay
US11672934B2 (en) 2020-05-12 2023-06-13 Covidien Lp Remote ventilator adjustment

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4775361A (en) 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
US4943290A (en) 1987-06-23 1990-07-24 Concept Inc. Electrolyte purging electrode tip
ATE131081T1 (de) 1988-01-21 1995-12-15 Massachusetts Inst Technology Molekültransport durch gewebe mit der verwendung von elektroporation.
CA2071321C (en) 1989-05-10 2000-12-12 Dan Sibalis Multi-signal electrical transdermal drug applicator
US5135478A (en) 1989-05-10 1992-08-04 Drug Delivery Systems Inc. Multi-signal electrical transdermal drug applicator
CA2040707C (en) * 1990-04-27 2002-07-09 Kenji Mitsushima Cephalosporin acetylhydrolase gene and protein encoded by said gene
WO1992013265A1 (en) 1991-01-24 1992-08-06 The University Of Maryland Method and apparatus for multi-dimensional phase fluorescence lifetime imaging
US5196709A (en) 1991-05-03 1993-03-23 University Of Maryland Systems Fluorometry method and apparatus using a semiconductor laser diode as a light source
EP0694164A1 (de) 1991-05-03 1996-01-31 Joseph R. Lakowicz Verfahren zur optischen Messung von chemischen Analyten
US5648269A (en) 1991-05-03 1997-07-15 Joseph R. Lakowicz pH and pCO2 sensing by luminescent lifetimes and energy transfer
US5571149A (en) 1991-05-21 1996-11-05 E.P., Inc. Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system
US5421817A (en) 1991-05-21 1995-06-06 E.P., Inc. Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system
US5203328A (en) 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
US5281825A (en) 1991-09-05 1994-01-25 The University Of Maryland School Of Medicine Phase fluorometry using a modulated electroluminescent lamp as a light source
US5423803A (en) 1991-10-29 1995-06-13 Thermotrex Corporation Skin surface peeling process using laser
AU3235793A (en) 1991-12-03 1993-06-28 Alza Corporation Iontophoretic delivery device and power supply therefor
CA2084734C (en) 1991-12-17 1998-12-01 John L. Haynes Iontophoresis system having features for reducing skin irritation
US5902272A (en) 1992-01-07 1999-05-11 Arthrocare Corporation Planar ablation probe and method for electrosurgical cutting and ablation
US5697882A (en) 1992-01-07 1997-12-16 Arthrocare Corporation System and method for electrosurgical cutting and ablation
US6024733A (en) 1995-06-07 2000-02-15 Arthrocare Corporation System and method for epidermal tissue ablation
US6210402B1 (en) 1995-11-22 2001-04-03 Arthrocare Corporation Methods for electrosurgical dermatological treatment
US6142992A (en) 1993-05-10 2000-11-07 Arthrocare Corporation Power supply for limiting power in electrosurgery
US6159194A (en) 1992-01-07 2000-12-12 Arthrocare Corporation System and method for electrosurgical tissue contraction
EP0552108B1 (de) 1992-01-17 1999-11-10 Lakowicz, Joseph R. Phasenmodulationsenergieübertragungsfluoroimmunassay
US5246867A (en) 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
US5165418B1 (en) 1992-03-02 1999-12-14 Nikola I Tankovich Blood sampling device and method using a laser
US5232441A (en) 1992-05-18 1993-08-03 Physion S.R.L. Method of treating schistosomal infestations by iontophoresis
US5462520A (en) 1992-08-17 1995-10-31 Genetronics, Inc. Transsurface drug delivery by electrofusion of microbubbles to the tissue surface
US5688233A (en) 1992-08-17 1997-11-18 Genetronics, Inc. Electronincorporation enhanced transdermal delivery of molecules
US5464386A (en) 1992-08-17 1995-11-07 Genetronics, Inc. Transdermal drug delivery by electroincorporation of vesicles
US5720772A (en) 1992-10-20 1998-02-24 Esc Medical Systems Ltd. Method and apparatus for therapeutic electromagnetic treatment
US5409835A (en) 1992-12-30 1995-04-25 The University Of Maryland At Baltimore Long-wavelength fluorescent probe compounds for calcium ions and their use in ratiometrically measuring calcium ion concentrations
US5380272A (en) 1993-01-28 1995-01-10 Scientific Innovations Ltd. Transcutaneous drug delivery applicator
JP2916736B2 (ja) 1993-03-04 1999-07-05 宇部興産株式会社 種子消毒剤
FR2703253B1 (fr) 1993-03-30 1995-06-23 Centre Nat Rech Scient Applicateur d'impulsions electriques pour traitement de tissus biologiques.
US5439440A (en) 1993-04-01 1995-08-08 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US6117109A (en) 1995-11-22 2000-09-12 Arthrocare Corporation Systems and methods for electrosurgical incisions on external skin surfaces
US6235020B1 (en) 1993-05-10 2001-05-22 Arthrocare Corporation Power supply and methods for fluid delivery in electrosurgery
US5445609A (en) 1993-05-28 1995-08-29 Alza Corporation Electrotransport agent delivery device having a disposable component and a removable liner
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
IL108775A (en) 1994-02-25 2003-09-17 Univ Ramot Method for efficient incorporation of molecules into cells
US5660991A (en) 1994-10-28 1997-08-26 Lakowicz; Joseph R. Long lifetime anisotropy (polarization) probes for clinical chemistry, immunoassays, affinity assays and biomedical research
US5697896A (en) 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
US5628310A (en) 1995-05-19 1997-05-13 Joseph R. Lakowicz Method and apparatus to perform trans-cutaneous analyte monitoring
US6238391B1 (en) 1995-06-07 2001-05-29 Arthrocare Corporation Systems for tissue resection, ablation and aspiration
US5983130A (en) 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
US6041253A (en) 1995-12-18 2000-03-21 Massachusetts Institute Of Technology Effect of electric field and ultrasound for transdermal drug delivery
US5983131A (en) 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
ES2536459T3 (es) 1995-08-29 2015-05-25 Nitto Denko Corporation Microporación de piel humana para administración de fármacos y aplicaciones de supervisión
US5688232A (en) 1995-09-28 1997-11-18 Becton Dickinson And Company Iontophoretic drug delivery device having an improved controller
US6228078B1 (en) 1995-11-22 2001-05-08 Arthrocare Corporation Methods for electrosurgical dermatological treatment
US6090106A (en) 1996-01-09 2000-07-18 Gyrus Medical Limited Electrosurgical instrument
US6002482A (en) 1996-01-17 1999-12-14 Spectrx, Inc. Disposable calibration device
US5792049A (en) 1996-01-17 1998-08-11 Spectrx, Inc. Spectroscopic system with disposable calibration device
US6045502A (en) 1996-01-17 2000-04-04 Spectrx, Inc. Analyzing system with disposable calibration device
US5860421A (en) 1996-01-17 1999-01-19 Spectrx, Inc. Apparatus and method for calibrating measurement systems
US5924981A (en) 1996-01-17 1999-07-20 Spectrx, Inc. Disposable calibration target
US6183434B1 (en) 1996-07-03 2001-02-06 Spectrx, Inc. Multiple mechanical microporation of skin or mucosa
US5911223A (en) 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US5759767A (en) 1996-10-11 1998-06-02 Joseph R. Lakowicz Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids
US6076012A (en) 1996-12-19 2000-06-13 Ep Technologies, Inc. Structures for supporting porous electrode elements
US5938657A (en) 1997-02-05 1999-08-17 Sahar Technologies, Inc. Apparatus for delivering energy within continuous outline
US6030399A (en) 1997-06-04 2000-02-29 Spectrx, Inc. Fluid jet blood sampling device and methods
US6009344A (en) 1997-07-25 1999-12-28 Becton, Dickinson And Company Iontophoretic drug delivery system
WO1999029364A1 (en) 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
DK1037686T3 (da) 1997-12-11 2006-01-02 Alza Corp Apparat til forögelse af transdermal gennemströmning af midler
US6055451A (en) 1997-12-12 2000-04-25 Spectrx, Inc. Apparatus and method for determining tissue characteristics
US6104952A (en) 1998-01-07 2000-08-15 Tu; Lily Chen Devices for treating canker sores, tissues and methods thereof
US6022316A (en) 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
US6173202B1 (en) 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6088606A (en) 1999-03-22 2000-07-11 Spectrx, Inc. Method and apparatus for determining a duration of a medical condition
EP1180053A4 (de) 1999-05-17 2006-11-08 Kevin S Marchitto Auf abstand und lokal gesteuerte zufuhr pharmazeutischer substanzen mittels elektromagnetischer energie
AU780752B2 (en) 1999-06-08 2005-04-14 Nitto Denko Corporation Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery

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US20030208152A1 (en) 2003-11-06
WO2002092163A2 (en) 2002-11-21
ATE335523T1 (de) 2006-09-15
EP1404406B1 (de) 2006-08-09
WO2002092163A3 (en) 2003-02-27
EP1404406A2 (de) 2004-04-07
US20020038101A1 (en) 2002-03-28
US6597946B2 (en) 2003-07-22

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