DE60216300D1 - Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption - Google Patents

Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption

Info

Publication number
DE60216300D1
DE60216300D1 DE60216300T DE60216300T DE60216300D1 DE 60216300 D1 DE60216300 D1 DE 60216300D1 DE 60216300 T DE60216300 T DE 60216300T DE 60216300 T DE60216300 T DE 60216300T DE 60216300 D1 DE60216300 D1 DE 60216300D1
Authority
DE
Germany
Prior art keywords
inhibitor
xanthom
treatment
sterol absorption
azetidinone derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60216300T
Other languages
English (en)
Other versions
DE60216300T2 (de
Inventor
R Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DE60216300D1 publication Critical patent/DE60216300D1/de
Application granted granted Critical
Publication of DE60216300T2 publication Critical patent/DE60216300T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE60216300T 2001-09-21 2002-09-19 Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption Expired - Lifetime DE60216300T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32394201P 2001-09-21 2001-09-21
US323942P 2001-09-21
PCT/US2002/029652 WO2003026643A2 (en) 2001-09-21 2002-09-19 Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors

Publications (2)

Publication Number Publication Date
DE60216300D1 true DE60216300D1 (de) 2007-01-04
DE60216300T2 DE60216300T2 (de) 2007-06-28

Family

ID=23261375

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60216300T Expired - Lifetime DE60216300T2 (de) 2001-09-21 2002-09-19 Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption

Country Status (13)

Country Link
US (2) US7132415B2 (de)
EP (1) EP1429756B1 (de)
JP (1) JP2005504091A (de)
AT (1) ATE345793T1 (de)
AU (1) AU2002336609B2 (de)
CA (1) CA2460340C (de)
CY (1) CY1105892T1 (de)
DE (1) DE60216300T2 (de)
DK (1) DK1429756T3 (de)
ES (1) ES2272776T3 (de)
MX (1) MXPA04002573A (de)
PT (1) PT1429756E (de)
WO (1) WO2003026643A2 (de)

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UY29607A1 (es) 2005-06-20 2007-01-31 Astrazeneca Ab Compuestos quimicos
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
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MX363161B (es) 2011-10-28 2019-03-13 Lumena Pharmaceuticals Inc Inhibidores de la recirculación de ácidos biliares para el tratamiento de hipercolemia y enfermedad hepática colestásica.
ES2633766T3 (es) 2011-10-28 2017-09-25 Lumena Pharmaceuticals Llc Inhibidores de reciclaje de ácido biliar para el tratamiento de enfermedades de hígado colestático pediátrico
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MX2015013196A (es) 2013-03-15 2016-04-15 Lumena Pharmaceuticals Inc Inhibidores de reciclaje de acidos biliares para el tratamiento de la enfermedad de reflujo gastroesofagico y esofago de barrett.
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CA2460340C (en) 2011-02-15
US7132415B2 (en) 2006-11-07
CA2460340A1 (en) 2003-04-03
ATE345793T1 (de) 2006-12-15
US20060217363A1 (en) 2006-09-28
WO2003026643A2 (en) 2003-04-03
EP1429756A2 (de) 2004-06-23
JP2005504091A (ja) 2005-02-10
WO2003026643A3 (en) 2003-07-03
PT1429756E (pt) 2007-01-31
EP1429756B1 (de) 2006-11-22
DE60216300T2 (de) 2007-06-28
ES2272776T3 (es) 2007-05-01
CY1105892T1 (el) 2011-02-02
AU2002336609B2 (en) 2006-08-24
DK1429756T3 (da) 2007-03-19

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