DE60227691D1 - Sprühtrocknungsverfahren - Google Patents
SprühtrocknungsverfahrenInfo
- Publication number
- DE60227691D1 DE60227691D1 DE60227691T DE60227691T DE60227691D1 DE 60227691 D1 DE60227691 D1 DE 60227691D1 DE 60227691 T DE60227691 T DE 60227691T DE 60227691 T DE60227691 T DE 60227691T DE 60227691 D1 DE60227691 D1 DE 60227691D1
- Authority
- DE
- Germany
- Prior art keywords
- liquid
- spray drying
- disperse
- supply
- drying process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/16—Evaporating by spraying
- B01D1/18—Evaporating by spraying to obtain dry solids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/16—Evaporating by spraying
- B01D1/20—Sprayers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33653801P | 2001-11-01 | 2001-11-01 | |
PCT/US2002/034909 WO2003037303A1 (en) | 2001-11-01 | 2002-10-31 | Spray drying methods and compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60227691D1 true DE60227691D1 (de) | 2008-08-28 |
Family
ID=23316549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60227691T Expired - Lifetime DE60227691D1 (de) | 2001-11-01 | 2002-10-31 | Sprühtrocknungsverfahren |
Country Status (10)
Country | Link |
---|---|
US (2) | US8524279B2 (de) |
EP (2) | EP1446104B2 (de) |
JP (1) | JP4837892B2 (de) |
KR (1) | KR100951750B1 (de) |
AT (1) | ATE401058T1 (de) |
AU (2) | AU2002342241B2 (de) |
CA (1) | CA2464656C (de) |
DE (1) | DE60227691D1 (de) |
TW (1) | TW200300696A (de) |
WO (1) | WO2003037303A1 (de) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
US20030203036A1 (en) | 2000-03-17 | 2003-10-30 | Gordon Marc S. | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients |
US7575761B2 (en) | 2000-06-30 | 2009-08-18 | Novartis Pharma Ag | Spray drying process control of drying kinetics |
WO2002009669A2 (en) * | 2000-08-01 | 2002-02-07 | Inhale Therapeutic Systems, Inc. | Apparatus and process to produce particles having a narrow size distribution and particles made thereby |
GB0027357D0 (en) | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
AU2002342241B2 (en) | 2001-11-01 | 2007-07-19 | Novartis Ag | Spray drying methods and compositions thereof |
GB0216562D0 (en) | 2002-04-25 | 2002-08-28 | Bradford Particle Design Ltd | Particulate materials |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
DE10234165B4 (de) * | 2002-07-26 | 2008-01-03 | Advanced Micro Devices, Inc., Sunnyvale | Verfahren zum Füllen eines Grabens, der in einem Substrat gebildet ist, mit einem isolierenden Material |
MXPA05007154A (es) * | 2002-12-30 | 2005-09-21 | Nektar Therapeutics | Atomizador prepeliculizacion. |
KR100453273B1 (ko) * | 2003-09-04 | 2004-10-15 | 주식회사 펩트론 | 초음파 이중공급노즐을 이용한 서방성 미립구의 제조 방법 |
GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
GB0415044D0 (en) * | 2004-07-05 | 2004-08-04 | Unilever Plc | Granule and process for its manufacture |
JP4739340B2 (ja) * | 2005-07-22 | 2011-08-03 | 田辺三菱製薬株式会社 | 口腔内速崩壊性錠 |
DE102006053375A1 (de) * | 2006-11-10 | 2008-05-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Mischung von Pulvern |
PL220269B1 (pl) * | 2008-04-21 | 2015-09-30 | Przedsiębiorstwo Produkcji Farmaceutycznej Hasco Lek Spółka Akcyjna | Kompozytowy nośnik leków proszkowych, sposób wytwarzania nośnika leków oraz urządzenie do wytwarzania cząstek nośnika kompozytowego |
CA2732585A1 (en) * | 2008-07-30 | 2010-02-04 | Stc.Unm | Formulations containing large-size carrier particles for dry powder inhalation aerosols |
PT3130396T (pt) * | 2009-03-27 | 2021-05-12 | Bend Res Inc | Processo de secagem por pulverização |
RU2533974C2 (ru) * | 2009-05-20 | 2014-11-27 | Басф Се | Способ получения сыпучего порошка, содержащего одно или несколько производных глицин-n,n-диуксусной кислоты, и применение сыпучего порошка для получения прессованных агломератов |
GB0909136D0 (en) | 2009-05-28 | 2009-07-01 | Profibrix Bv | Dry powder composition |
WO2010136588A2 (en) * | 2009-05-28 | 2010-12-02 | Profibrix B.V. | Dry powder fibrin sealant |
KR20120116421A (ko) * | 2009-11-25 | 2012-10-22 | 주식회사 메디진바이오 | 성장 호르몬을 포함하는 흡입형 분말 제제의 nmda 수용체 기능저하-관련 질환을 예방 또는 치료하기 위한 용도 |
NZ600812A (en) | 2010-01-08 | 2014-08-29 | Profibrix Bv | Dry powder fibrin sealant |
CA2797681C (en) * | 2010-04-27 | 2018-12-18 | University Of Maine System Board Of Trustees | Method for drying cellulose nanofibrils |
PT2611530T (pt) | 2010-09-03 | 2019-05-09 | Bend Res Inc | Aparelho de secagem por pulverização e métodos de utilização do mesmo |
US9084976B2 (en) | 2010-09-03 | 2015-07-21 | Bend Research, Inc. | Spray-drying apparatus and methods of using the same |
WO2012040502A1 (en) | 2010-09-24 | 2012-03-29 | Bend Research, Inc. | High-temperature spray drying process and apparatus |
MX350838B (es) | 2011-02-11 | 2017-09-18 | Grain Proc Corporation * | Composicion de sal. |
US9572774B2 (en) | 2011-05-19 | 2017-02-21 | Savara Inc. | Dry powder vancomycin compositions and associated methods |
CA2981038C (en) * | 2011-05-19 | 2018-09-25 | Savara Inc. | Dry powder vancomycin compositions and associated methods |
RU2013155713A (ru) | 2011-07-06 | 2015-08-20 | Профибрикс Бв | Составы для лечения ран |
JP5943820B2 (ja) * | 2012-11-30 | 2016-07-05 | 三菱重工業株式会社 | 脱水濾液の噴霧乾燥装置及び排ガス処理システム |
KR102074543B1 (ko) * | 2013-03-14 | 2020-02-06 | 노파르티스 아게 | 분무-블렌딩을 통한 분무-건조 제제의 탈무정형화 |
IN2013CH04500A (de) | 2013-10-04 | 2015-04-10 | Kennametal India Ltd | |
EP2999933B1 (de) * | 2014-01-27 | 2020-05-27 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Natural Resources Canada | Verfahren zum trocknen und pulverisieren funktioneller lebensmittel, nutrazeutika und natürlicher gesundheitsinhaltsstoffe |
PT107567B (pt) * | 2014-03-31 | 2019-02-13 | Hovione Farm S A | Secador por atomização com atomizador múltiplo, método para o aumento de escala de pós para inalação secos por dispositivo de atomização múltiplo e uso de vários atomizadores num secador por atomização |
US10252270B2 (en) * | 2014-09-08 | 2019-04-09 | Arizona Board Of Regents On Behalf Of Arizona State University | Nozzle apparatus and methods for use thereof |
US9561184B2 (en) | 2014-09-19 | 2017-02-07 | Velico Medical, Inc. | Methods and systems for multi-stage drying of plasma |
US10806770B2 (en) | 2014-10-31 | 2020-10-20 | Monash University | Powder formulation |
US11364203B2 (en) | 2014-10-31 | 2022-06-21 | Bend Reserch, Inc. | Process for forming active domains dispersed in a matrix |
RU2731212C2 (ru) | 2015-09-09 | 2020-08-31 | Новартис Аг | Направленная доставка высушенных распылением композиций в легкие |
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AR106558A1 (es) * | 2015-11-03 | 2018-01-24 | Spraying Systems Co | Aparato y método de secado por pulverización |
US20170135969A1 (en) | 2015-11-12 | 2017-05-18 | Jds Therapeutics, Llc | Topical arginine-silicate-inositol for wound healing |
MX2019002468A (es) | 2016-09-01 | 2019-09-18 | Jds Therapeutics Llc | Composiciones de biotinato de magnesio y metodos de uso. |
CA3064530A1 (en) | 2017-06-12 | 2018-12-20 | Novartis Ag | Amorphous nanostructured pharmaceutical materials |
US10933343B2 (en) * | 2017-10-27 | 2021-03-02 | Spraying Systems Co. | Spray dryer system and method |
US20210069106A1 (en) | 2018-01-26 | 2021-03-11 | Novartis Ag | High dose delivery of inhaled therapeutics |
WO2020092431A1 (en) | 2018-11-02 | 2020-05-07 | Nutrition 21, Llc | Compositions containing inositol-stabilized arginine silicate complexes and inositol for improving cognitive function in video gamers |
RU2702095C1 (ru) * | 2018-12-25 | 2019-10-04 | Акционерное общество "Радиевый институт имени В.Г. Хлопина" | Способ получения монофазных солей актинидов и устройство для их получения |
US20220118471A1 (en) * | 2018-12-28 | 2022-04-21 | Spray Nozzle Engineering Pty. Ltd. | Spray nozzle |
KR20220019027A (ko) | 2019-06-10 | 2022-02-15 | 레스피라 테라퓨틱스 인크. | 담체-기반 제제 및 관련 방법 |
KR102183845B1 (ko) * | 2019-11-22 | 2020-11-30 | 주식회사 지씨에스 | 폴리-l-락틱산 필러와 히알루론산 필러 결합체를 함유하는 서방성 주사제제 및 그 제조방법 |
GB2613672A (en) * | 2019-12-16 | 2023-06-14 | Nutrition 21 Llc | Methods of production of aginine-silicate complexes |
CN112704890B (zh) * | 2020-11-05 | 2023-02-28 | 中国恩菲工程技术有限公司 | 液体进料装置和液体进料控制方法 |
EP4039348B1 (de) * | 2021-02-03 | 2023-06-07 | Vysoká skola chemicko-technologická v Praze | Vorrichtung zur kontinuierlichen sprühtrocknung mit variabler eintrittszusammensetzung, verfahren zur kontinuierlichen herstellung von mehrkomponentenpulvern durch sprühtrocknung und deren verwendung |
CN114181815B (zh) * | 2021-12-06 | 2023-10-20 | 清华大学 | 一种大流量环境空气生物气溶胶采样装置和方法 |
US11841189B1 (en) | 2022-09-15 | 2023-12-12 | Velico Medical, Inc. | Disposable for a spray drying system |
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-
2002
- 2002-10-31 AU AU2002342241A patent/AU2002342241B2/en not_active Ceased
- 2002-10-31 KR KR1020047006672A patent/KR100951750B1/ko not_active IP Right Cessation
- 2002-10-31 DE DE60227691T patent/DE60227691D1/de not_active Expired - Lifetime
- 2002-10-31 CA CA2464656A patent/CA2464656C/en not_active Expired - Fee Related
- 2002-10-31 US US10/284,960 patent/US8524279B2/en active Active
- 2002-10-31 WO PCT/US2002/034909 patent/WO2003037303A1/en active IP Right Grant
- 2002-10-31 EP EP02776395A patent/EP1446104B2/de not_active Expired - Lifetime
- 2002-10-31 JP JP2003539647A patent/JP4837892B2/ja not_active Expired - Lifetime
- 2002-10-31 EP EP08160325A patent/EP1992335A1/de not_active Ceased
- 2002-10-31 AT AT02776395T patent/ATE401058T1/de not_active IP Right Cessation
- 2002-10-31 TW TW091132307A patent/TW200300696A/zh unknown
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2009
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Also Published As
Publication number | Publication date |
---|---|
US8936813B2 (en) | 2015-01-20 |
CA2464656A1 (en) | 2003-05-08 |
WO2003037303A1 (en) | 2003-05-08 |
EP1992335A1 (de) | 2008-11-19 |
TW200300696A (en) | 2003-06-16 |
JP2005511555A (ja) | 2005-04-28 |
AU2009202578B2 (en) | 2012-02-09 |
AU2002342241B2 (en) | 2007-07-19 |
EP1446104A1 (de) | 2004-08-18 |
KR100951750B1 (ko) | 2010-04-09 |
ATE401058T1 (de) | 2008-08-15 |
US20030124193A1 (en) | 2003-07-03 |
EP1446104B1 (de) | 2008-07-16 |
KR20050042052A (ko) | 2005-05-04 |
AU2009202578A1 (en) | 2009-07-16 |
JP4837892B2 (ja) | 2011-12-14 |
EP1446104B2 (de) | 2011-08-03 |
AU2009202578B8 (en) | 2012-04-05 |
CA2464656C (en) | 2013-07-16 |
US20120038073A1 (en) | 2012-02-16 |
US8524279B2 (en) | 2013-09-03 |
AU2009202578A8 (en) | 2012-04-05 |
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