DE60230649D1 - Systeme, verfahren und geräte zur herstellung von tabletten - Google Patents

Systeme, verfahren und geräte zur herstellung von tabletten

Info

Publication number
DE60230649D1
DE60230649D1 DE60230649T DE60230649T DE60230649D1 DE 60230649 D1 DE60230649 D1 DE 60230649D1 DE 60230649 T DE60230649 T DE 60230649T DE 60230649 T DE60230649 T DE 60230649T DE 60230649 D1 DE60230649 D1 DE 60230649D1
Authority
DE
Germany
Prior art keywords
systems
methods
devices
dosage forms
producing tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230649T
Other languages
English (en)
Inventor
Harry S Sowden
Bernard F Plantz
Shun-Por Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Application granted granted Critical
Publication of DE60230649D1 publication Critical patent/DE60230649D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/368Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/02Apparatus specially adapted for manufacture or treatment of sweetmeats or confectionery; Accessories therefor
    • A23G3/04Sugar-cookers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005Coating of tablets or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B11/00Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/005Control arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B15/00Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/0005Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses
    • B30B15/0017Deairing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2853Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2873Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893Tablet coating processes
DE60230649T 2001-09-28 2002-09-26 Systeme, verfahren und geräte zur herstellung von tabletten Expired - Lifetime DE60230649D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/966,497 US7122143B2 (en) 2001-09-28 2001-09-28 Methods for manufacturing dosage forms
PCT/US2002/030650 WO2003028619A2 (en) 2001-09-28 2002-09-26 Systems, methods and apparatuses for manufacturing dosage forms

Publications (1)

Publication Number Publication Date
DE60230649D1 true DE60230649D1 (de) 2009-02-12

Family

ID=25511500

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230649T Expired - Lifetime DE60230649D1 (de) 2001-09-28 2002-09-26 Systeme, verfahren und geräte zur herstellung von tabletten

Country Status (10)

Country Link
US (3) US7122143B2 (de)
EP (1) EP1432378B1 (de)
JP (1) JP2005504589A (de)
KR (1) KR20040039459A (de)
CN (1) CN1635863A (de)
AT (1) ATE418953T1 (de)
CA (1) CA2461873C (de)
DE (1) DE60230649D1 (de)
MX (1) MXPA04002969A (de)
WO (1) WO2003028619A2 (de)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7217381B2 (en) * 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US20040146559A1 (en) * 2002-09-28 2004-07-29 Sowden Harry S. Dosage forms having an inner core and outer shell with different shapes
JP2005508325A (ja) 2001-09-28 2005-03-31 マクニール−ピーピーシー・インコーポレイテッド 内側コア及び外側シェルを有する投薬形態
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US20060210633A1 (en) * 2003-04-03 2006-09-21 Sun Pharmaceutical Industries Limited Programmed drug delivery system
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US20050074514A1 (en) * 2003-10-02 2005-04-07 Anderson Oliver B. Zero cycle molding systems, methods and apparatuses for manufacturing dosage forms
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US20050196447A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196448A1 (en) * 2004-03-05 2005-09-08 Hai Yong Huang Polymeric compositions and dosage forms comprising the same
US20050196446A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196442A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
FR2872718B1 (fr) * 2004-07-08 2006-10-20 Sidel Sa Sa Procede de traitement d'un recipient comportant des phases de pompage a vide et machine pour sa mise en oeuvre
US8383159B2 (en) * 2004-10-27 2013-02-26 Mcneil-Ppc, Inc. Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088586A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088593A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088587A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060087051A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070190133A1 (en) * 2004-10-27 2007-08-16 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070281022A1 (en) * 2004-10-27 2007-12-06 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060093560A1 (en) * 2004-10-29 2006-05-04 Jen-Chi Chen Immediate release film coating
US7404708B2 (en) * 2004-12-07 2008-07-29 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
US7530804B2 (en) * 2004-12-07 2009-05-12 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
US8211078B2 (en) 2005-02-17 2012-07-03 The Procter And Gamble Company Sanitary napkins capable of taking complex three-dimensional shape in use
US9579238B2 (en) 2005-02-17 2017-02-28 The Procter & Gamble Company Sanitary napkins capable of taking complex three-dimensional shape in use
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US20060233882A1 (en) * 2005-04-15 2006-10-19 Sowden Harry S Osmotic dosage form
WO2006116718A2 (en) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Pharma-informatics system
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
US20070048366A1 (en) * 2005-08-26 2007-03-01 Jen-Chi Chen Gelatin-based coatings having improved durability
US7485609B2 (en) * 2005-09-29 2009-02-03 Kimberly-Clark Worldwide, Inc. Encapsulated liquid cleanser
US20070224258A1 (en) * 2006-03-22 2007-09-27 Bunick Frank J Dosage forms having a randomized coating
US20070231389A1 (en) * 2006-03-28 2007-10-04 Bunick Frank J Non-homogenous dosage form coatings
US20080035667A1 (en) * 2006-06-07 2008-02-14 Osg Norwich Pharmaceuticals, Inc. Liquid delivery system
US20080075766A1 (en) * 2006-09-25 2008-03-27 Shun-Por Li Multi-core dosage form having transparent outer coating
JP5389656B2 (ja) 2006-10-20 2014-01-15 マクニール−ピーピーシー・インコーポレーテツド アセトアミノフェン/イブプロフェンの組み合わせおよびこれらの使用方法
MX2009004439A (es) * 2006-10-25 2009-05-11 Mcneil Ppc Inc Composicion de ibuprofeno.
BRPI0821735A2 (pt) * 2007-12-21 2015-06-16 Mcneil Ppc Inc Fabricação de tablete
WO2010051312A1 (en) * 2008-10-31 2010-05-06 Mcneil-Ppc, Inc. Osmotic tablet with a compressed outer coating
KR200453578Y1 (ko) * 2009-03-06 2011-05-17 박대호 시각장애인용 보도블럭
MX2011011506A (es) 2009-04-28 2012-05-08 Proteus Biomedical Inc Marcadores de eventos ingeribles altamente confiables y metodos para utilizar los mismos.
TWI471127B (zh) 2009-04-29 2015-02-01 Intervet Int Bv 供人類使用之口服崩解錠劑的製備方法、所製得之口服崩解錠劑、以及含有該口服崩解錠劑的包裝物
UA109424C2 (uk) * 2009-12-02 2015-08-25 Фармацевтичний продукт, фармацевтична таблетка з електронним маркером і спосіб виготовлення фармацевтичної таблетки
BR112012025650A2 (pt) 2010-04-07 2020-08-18 Proteus Digital Health, Inc. dispositivo ingerível miniatura
EP2409676A1 (de) * 2010-07-06 2012-01-25 Intervet International B.V. Verfahren zur Dosierung einer Flüssigformulierung mit einer medizinischen Substanz
EP2642983A4 (de) 2010-11-22 2014-03-12 Proteus Digital Health Inc Einnehmbare vorrichtung mit einem pharmazeutischen produkt
JP5673287B2 (ja) * 2011-03-29 2015-02-18 東洋製罐株式会社 圧縮成形システム
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9445971B2 (en) * 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
DE102012010263A1 (de) * 2012-05-25 2013-11-28 Bleistahl-Produktions Gmbh & Co Kg Rundtaktpressmaschine
EP3744509B1 (de) 2012-08-21 2022-03-23 Vertera Inc. Verfahren zur herstellung poröser artikel
WO2014074797A1 (en) * 2012-11-09 2014-05-15 Civitas Therapeutics, Inc. Ultra low density pulmonary powders
US11149123B2 (en) 2013-01-29 2021-10-19 Otsuka Pharmaceutical Co., Ltd. Highly-swellable polymeric films and compositions comprising the same
JP5941240B2 (ja) 2013-03-15 2016-06-29 プロテウス デジタル ヘルス, インコーポレイテッド 金属検出器装置、システム、および方法
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
WO2015095230A1 (en) * 2013-12-16 2015-06-25 Massachusetts Institute Of Technology Micromolded or 3-d printed pulsatile release vaccine formulations
US9085665B1 (en) 2014-12-31 2015-07-21 Vertera, Inc. Method for producing porous material
US9498922B2 (en) 2014-06-26 2016-11-22 Vertera, Inc. Apparatus and process for producing porous devices
US9517593B2 (en) 2014-06-26 2016-12-13 Vertera, Inc. Apparatus and process for producing porous devices
US9504550B2 (en) 2014-06-26 2016-11-29 Vertera, Inc. Porous devices and processes for producing same
US10328023B2 (en) 2015-04-07 2019-06-25 Church & Dwight Co., Inc. Multicomponent gummy compositions with hard core
USD815281S1 (en) 2015-06-23 2018-04-10 Vertera, Inc. Cervical interbody fusion device
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
USD809576S1 (en) * 2016-07-08 2018-02-06 Ackley Machine Corporation Carrier link for longitudinally compressed tablet
TWI728155B (zh) 2016-07-22 2021-05-21 日商大塚製藥股份有限公司 可攝食事件標示器之電磁感測及偵測
AU2017348094B2 (en) 2016-10-26 2022-10-13 Otsuka Pharmaceutical Co., Ltd. Methods for manufacturing capsules with ingestible event markers
DE102016123279B4 (de) * 2016-12-01 2019-02-21 Fette Compacting Gmbh Verfahren und System zum Zuführen eines Schmier- oder Trennmittels zu Presswerkzeugen einer Tablettenpresse
GR1009361B (el) 2017-05-11 2018-09-17 Κωνσταντινος Ηλια Θεοδοσοπουλος Συστημα παραγωγης μεσω τρισδιαστατης εκτυπωσης, δισκιων, κοκκιων και καψουλων
US11491540B2 (en) * 2017-08-21 2022-11-08 Sumitomo Electric Sintered Alloy, Ltd. Sizing apparatus
DE102017130885B4 (de) * 2017-12-21 2020-01-23 Fette Compacting Gmbh Verfahren zum Regeln der Rotordrehzahl eines Rotors einer Rundläufertablettenpresse sowie Rundläufertablettenpresse
CN112272557B (zh) * 2018-06-11 2023-11-03 康蒂纽斯制药公司 对药物片剂进行模制及包衣的系统
KR102155872B1 (ko) * 2020-05-08 2020-09-14 주식회사 동해종합기술공사 탄산화 깊이 측정장치
CN112336625B (zh) * 2020-10-05 2021-12-14 山东赫尔希胶囊有限公司 一种用于胶囊生产的外壳成型装置
CN117480047A (zh) * 2021-07-02 2024-01-30 工业制药资源公司 具有多排转塔的旋转式压片机

Family Cites Families (343)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US545832A (en) 1895-09-03 Machine for compressing and molding popcorn
US3371136A (en) 1968-02-27 United States Borax Chem Detergent tablet forming machine
US449983A (en) 1891-04-07 Nut-lock
US596768A (en) * 1898-01-04 Automatically-operated stringed musical instrument
US599865A (en) 1898-03-01 Emanuel l
US582438A (en) 1897-05-11 John scheidler
US1036647A (en) 1911-06-19 1912-08-27 St Louis Briquette Machine Company Briquet-machine.
US1437816A (en) 1922-07-26 1922-12-05 Howard S Paine Process for preparing fondant or chocolate soft cream centers
US1505827A (en) * 1923-04-25 1924-08-19 Villasenor Eduardo Tablet-making machine
US1900012A (en) 1925-09-04 1933-03-07 Western Cartridge Co Process of and apparatus for making wads
US2026940A (en) * 1934-12-13 1936-01-07 Harbison Walker Refractories Shaping refractory articles
US2361348A (en) * 1939-10-12 1944-10-24 Spalding A G & Bros Inc Process and apparatus for making balls
US2307371A (en) 1941-08-13 1943-01-05 Ray O Vac Co Molding process
US2415997A (en) 1946-01-12 1947-02-18 John W Eldred Article handling apparatus
US2823789A (en) 1952-05-06 1958-02-18 Gilman Engineering & Mfg Corp Parts feeder ribbon
US2849965A (en) 1954-04-15 1958-09-02 John Holroyd & Company Ltd Machines for use in the production of coated tablets and the like
GB759081A (en) 1954-04-15 1956-10-10 John Holroyd And Company Ltd Improvements relating to machines for the production of coated tablets and the like
US2966431A (en) 1956-03-24 1960-12-27 Basf Ag Separation of filter material from carbon black
US2946298A (en) 1957-11-13 1960-07-26 Arthur Colton Company Compression coating tablet press
US2931276A (en) 1958-02-10 1960-04-05 Jagenberg Werke Ag Methods of and means for producing, processing, and for treating articles
GB866681A (en) 1958-05-22 1961-04-26 May & Baker Ltd N-substituted piperidines
GB888038A (en) 1959-12-16 1962-01-24 William Warren Triggs C B E Medicinal tablet
GB936386A (en) 1959-01-16 1963-09-11 Wellcome Found Pellets for supplying biologically active substances to ruminants
US2963993A (en) 1959-01-20 1960-12-13 John Holroyd & Company Ltd Machines for making coated tablets by compression
US3096248A (en) 1959-04-06 1963-07-02 Rexall Drug & Chemical Company Method of making an encapsulated tablet
US3029752A (en) 1959-07-20 1962-04-17 Stokes F J Corp Tablet making machine
GB972128A (en) 1960-01-21 1964-10-07 Wellcome Found Pellets for supplying biologically active substances to ruminants and the manufacture of such pellets
GB990784A (en) 1960-05-23 1965-05-05 Dunlop Rubber Co Improvements in or relating to balls
GB994742A (en) 1960-09-09 1965-06-10 Wellcome Found Pharmaceutical tablets containing anthelmintics, and the manufacture thereof
US3108046A (en) 1960-11-25 1963-10-22 Smith Kline French Lab Method of preparing high dosage sustained release tablet and product of this method
NL272604A (de) 1960-12-28
US3430535A (en) 1961-08-25 1969-03-04 Independent Lock Co Key cutter
NL297357A (de) 1962-08-31
US3185626A (en) 1963-03-06 1965-05-25 Sterling Drug Inc Tablet coating method
US3300063A (en) 1965-01-25 1967-01-24 Mayer & Co Inc O Vacuum gripping apparatus
FR1603314A (en) 1965-02-23 1971-04-05 Pharmaceutical tablets - having a core and a matrix material
US3328840A (en) * 1965-04-23 1967-07-04 Pentronix Inc Powder compacting press
US3279360A (en) 1965-09-13 1966-10-18 Miehle Goss Dexter Inc Machine for printing on cylindrical articles
US3330400A (en) 1966-03-08 1967-07-11 Miehle Goss Dexter Inc Mechanism for transferring cylindrical articles
GB1212535A (en) 1966-10-12 1970-11-18 Shionogi & Co Method and apparatus for producing molded article
US3458968A (en) 1966-11-16 1969-08-05 Lester Gregory Jr Dispensing and feed mechanism
GB1144915A (en) 1966-11-24 1969-03-12 Armour Pharma Improvements in or relating to pastille formulations
US3656518A (en) 1967-03-27 1972-04-18 Perry Ind Inc Method and apparatus for measuring and dispensing predetermined equal amounts of powdered material
US3430532A (en) 1967-07-13 1969-03-04 Usm Corp Means for making pellets,particularly explosive pellets
US3518866A (en) 1967-12-12 1970-07-07 Bliss Co Feed or discharge mechanism for a forming press
US3563170A (en) 1968-04-16 1971-02-16 Reynolds Metals Co Machine for marking the exterior cylindrical surfaces of cans in a continous nonidexing manner
US3605479A (en) 1968-05-08 1971-09-20 Textron Inc Forming press
US3584114A (en) 1968-05-22 1971-06-08 Hoffmann La Roche Free-flowing powders
US3567043A (en) 1968-08-05 1971-03-02 Sun Chemical Corp Transfer assembly for use with container printing machines
US3627583A (en) 1969-04-29 1971-12-14 Sucrest Corp Direct compression vehicles
US3640654A (en) * 1970-06-25 1972-02-08 Wolverine Pentronix Die and punch assembly for compacting powder and method of assembly
US3832252A (en) 1970-09-29 1974-08-27 T Higuchi Method of making a drug-delivery device
CH569482A5 (de) 1970-12-23 1975-11-28 Boehringer Sohn Ingelheim
US3811552A (en) 1971-01-11 1974-05-21 Lilly Co Eli Capsule inspection apparatus and method
US3726622A (en) 1971-08-20 1973-04-10 Wolverine Pentronix Compacting apparatus
DE2157465C3 (de) 1971-11-19 1975-04-24 Werner & Pfleiderer, 7000 Stuttgart Füllvorrichtung für eine hydraulische Blockpresse
US3975888A (en) 1972-04-26 1976-08-24 R. A. Jones & Company, Inc. Method and apparatus for forming, filling and sealing packages
US3851751A (en) 1972-04-26 1974-12-03 Jones & Co Inc R A Method and apparatus for forming, filling and sealing packages
US3912441A (en) 1972-12-13 1975-10-14 Yasuo Shimada Compressing roll in rotary power compression molding machine
DE2309202A1 (de) 1973-02-21 1974-08-29 Schering Ag Arzneiformen mit mikroverkapseltem arzneimittelwirkstoff
US3884143A (en) 1973-09-04 1975-05-20 Hartnett Co R W Conveyor link for tablet printing apparatus
US3891375A (en) 1974-01-21 1975-06-24 Vector Corp Tablet press
GB1497044A (en) 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
US3988403A (en) 1974-07-09 1976-10-26 Union Carbide Corporation Process for producing molded structural foam article having a surface that reproducibly and faithfully replicates the surface of the mold
US4139589A (en) 1975-02-26 1979-02-13 Monique Beringer Process for the manufacture of a multi-zone tablet and tablet manufactured by this process
US3999922A (en) * 1975-04-16 1976-12-28 Yasuo Shimada Rotary tableting machine
US4230693A (en) 1975-04-21 1980-10-28 Armour-Dial, Inc. Antacid tablets and processes for their preparation
FR2312247A1 (fr) 1975-05-30 1976-12-24 Parcor Derives de la thieno-pyridine, leur procede de preparation et leurs applications
US4061452A (en) * 1975-10-06 1977-12-06 Wolverine Aluminum Corporation Apparatus for producing spherical articles
US4061453A (en) * 1975-10-06 1977-12-06 Wolverine Aluminum Corporation Tooling for a powder compacting press
US4097606A (en) 1975-10-08 1978-06-27 Bristol-Myers Company APAP Tablet containing an alkali metal carboxymethylated starch and processes for manufacturing same
SE414386B (sv) 1976-03-10 1980-07-28 Aco Laekemedel Ab Sett att framstella och samtidigt forpacka farmaceutiska dosenheter
JPS52119474A (en) * 1976-03-31 1977-10-06 Hata Iron Works Rotary powder compression molder
GB1548022A (en) 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
DE2752971C2 (de) * 1977-11-28 1982-08-19 Lev Nikolaevič Moskva Koškin Spritzgießmaschine zum Herstellen von Spritzgußteilen aus thermoplastischen Werkstoffen
GB2030042A (en) 1978-09-21 1980-04-02 Beecham Group Ltd Antacid fondant
US4173626A (en) 1978-12-11 1979-11-06 Merck & Co., Inc. Sustained release indomethacin
US4271142A (en) 1979-06-18 1981-06-02 Life Savers, Inc. Portable liquid antacids
JPS5827162B2 (ja) 1979-08-24 1983-06-08 株式会社ヤクルト本社 定速搬送機構
NL7906689A (nl) 1979-09-06 1981-03-10 Dawsonville Corp Nv Tatoueerinrichting.
US4273793A (en) 1979-10-26 1981-06-16 General Foods Corporation Apparatus and process for the preparation of gasified confectionaries by pressurized injection molding
US4271206A (en) 1979-10-26 1981-06-02 General Foods Corporation Gasified candy having a predetermined shape
US4543370A (en) 1979-11-29 1985-09-24 Colorcon, Inc. Dry edible film coating composition, method and coating form
US4473526A (en) 1980-01-23 1984-09-25 Eugen Buhler Method of manufacturing dry-pressed molded articles
US4292017A (en) 1980-07-09 1981-09-29 Doepel Wallace A Apparatus for compressing tablets
US4362757A (en) 1980-10-22 1982-12-07 Amstar Corporation Crystallized, readily water dispersible sugar product containing heat sensitive, acidic or high invert sugar substances
US4683256A (en) 1980-11-06 1987-07-28 Colorcon, Inc. Dry edible film coating composition, method and coating form
US4327076A (en) 1980-11-17 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US5002970A (en) 1981-07-31 1991-03-26 Eby Iii George A Flavor masked ionizable zinc compositions for oral absorption
US4372942A (en) 1981-08-13 1983-02-08 Beecham Inc. Candy base and liquid center hard candy made therefrom
DE3144678A1 (de) 1981-11-10 1983-05-19 Eugen Dipl.-Ing. 8871 Burtenbach Bühler Verfahren und einrichtung zur herstellung von formlingen aus einer rieselfaehigen masse
JPS58152813A (ja) 1982-03-08 1983-09-10 Sumitomo Chem Co Ltd 鮮明な刻印を有する錠剤およびその製法
US4449983A (en) 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4576604A (en) 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
US4882167A (en) 1983-05-31 1989-11-21 Jang Choong Gook Dry direct compression compositions for controlled release dosage forms
US4533345A (en) 1983-06-14 1985-08-06 Fertility & Genetics Associates Uterine catheter
US4749575A (en) 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
AU591171B2 (en) 1983-11-02 1989-11-30 Alza Corporation Dispenser for delivering thermo-responsive composition
NL194820C (nl) 1983-11-02 2003-04-03 Alza Corp Preparaat voor de afgifte van een op warmte reagerende samenstelling.
US4781714A (en) 1983-11-02 1988-11-01 Alza Corporation Dispenser for delivering thermo-responsive composition
DE3404108A1 (de) 1984-02-07 1985-08-14 Kilian & Co GmbH, 5000 Köln Tablettenpresse
US4518335A (en) 1984-03-14 1985-05-21 Allied Corporation Dilatant mold and dilatant molding apparatus
JPS60217106A (ja) 1984-04-12 1985-10-30 高橋 信之 無機粉末凍結成形法
US4661521A (en) 1984-04-30 1987-04-28 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
US4528335A (en) 1984-05-18 1985-07-09 Phillips Petroleum Company Polymer blends
US4643894A (en) 1984-07-24 1987-02-17 Colorcon, Inc. Maltodextrin coating
US4828841A (en) 1984-07-24 1989-05-09 Colorcon, Inc. Maltodextrin coating
US4894234A (en) 1984-10-05 1990-01-16 Sharma Shri C Novel drug delivery system for antiarrhythmics
US4684534A (en) 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
US4587330A (en) * 1985-02-22 1986-05-06 Atlantic Richfield Company Purification of polymer solutions
CA1234717A (en) 1985-06-28 1988-04-05 Leslie F. Knebl Moist chewing gum composition
GB8517073D0 (en) 1985-07-05 1985-08-14 Hepworth Iron Co Ltd Pipe pipe couplings &c
DK8603837A (de) 1985-08-13 1987-02-14
US4665116A (en) 1985-08-28 1987-05-12 Turtle Wax, Inc. Clear cleaner/polish composition
US5188840A (en) 1985-09-26 1993-02-23 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
US4898733A (en) 1985-11-04 1990-02-06 International Minerals & Chemical Corp. Layered, compression molded device for the sustained release of a beneficial agent
US4853249A (en) 1985-11-15 1989-08-01 Taisho Pharmaceutical Co., Ltd. Method of preparing sustained-release pharmaceutical/preparation
US5229164A (en) 1985-12-19 1993-07-20 Capsoid Pharma Gmbh Process for producing individually dosed administration forms
JPS62230600A (ja) 1986-03-31 1987-10-09 東洋ゴム工業株式会社 伸縮可能なフオ−クを備えたフオ−クリフト
DE3610878A1 (de) 1986-04-01 1987-10-08 Boehringer Ingelheim Kg Formlinge aus pellets
US4873231A (en) 1986-04-08 1989-10-10 Smith Walton J Decreasing the toxicity of an ibuprofen salt
US4857330A (en) 1986-04-17 1989-08-15 Alza Corporation Chlorpheniramine therapy
US4802924A (en) 1986-06-19 1989-02-07 Colorcon, Inc. Coatings based on polydextrose for aqueous film coating of pharmaceutical food and confectionary products
IE58401B1 (en) 1986-06-20 1993-09-08 Elan Corp Plc Controlled absorption pharmaceutical composition
US4757090A (en) 1986-07-14 1988-07-12 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
US4762719A (en) 1986-08-07 1988-08-09 Mark Forester Powder filled cough product
CA1290526C (en) 1986-11-07 1991-10-15 Marianne Wieser Mold and die operation
DE3640574A1 (de) 1986-11-27 1988-06-09 Katjes Fassin Gmbh & Co Kg Verfahren zur herstellung eines essbaren pralinenfoermigen produktes und vorrichtung fuer die durchfuehrung des verfahrens
US4828845A (en) 1986-12-16 1989-05-09 Warner-Lambert Company Xylitol coated comestible and method of preparation
IT1201136B (it) 1987-01-13 1989-01-27 Resa Farma Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive
US4801461A (en) 1987-01-28 1989-01-31 Alza Corporation Pseudoephedrine dosage form
US5234099A (en) 1987-02-20 1993-08-10 Mcneil-Ppc, Inc. Coated medicaments and apparatus and methods for making same
US4820524A (en) 1987-02-20 1989-04-11 Mcneilab, Inc. Gelatin coated caplets and process for making same
US4808413A (en) 1987-04-28 1989-02-28 E. R. Squibb & Sons, Inc. Pharmaceutical compositions in the form of beadlets and method
US5100275A (en) * 1987-05-20 1992-03-31 Schirrmacher Wendell E Quick locking fasteners
US4792448A (en) 1987-06-11 1988-12-20 Pfizer Inc. Generic zero order controlled drug delivery system
US4813818A (en) 1987-08-25 1989-03-21 Michael Sanzone Apparatus and method for feeding powdered materials
US4996061A (en) 1987-10-07 1991-02-26 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol-decongestant combination
US4851226A (en) 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
DE3739551A1 (de) 1987-11-21 1989-06-01 Focke & Co Vorrichtung zum transport von zigaretten-packungen im zusammenhang mit einer verpackungsmaschine
FR2623976B1 (fr) 1987-12-08 1994-02-25 So Ge Val Comprime pour animal domestique
IT1221567B (it) 1987-12-30 1990-07-12 Ima Spa Macchina comprimitrice per la realizzazione di compresse
US4894236A (en) 1988-01-12 1990-01-16 Choong-Gook Jang Direct compression tablet binders for acetaminophen
US5030447A (en) 1988-03-31 1991-07-09 E. R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability
US4929446A (en) 1988-04-19 1990-05-29 American Cyanamid Company Unit dosage form
US5088915A (en) 1988-06-08 1992-02-18 Korsch Ohg Maschinenfabrik Coated-core press
DE3822095A1 (de) 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab Neue arzneimittelformulierung sowie verfahren zu deren herstellung
DE3830353A1 (de) 1988-09-07 1990-03-15 Basf Ag Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
JPH0816051B2 (ja) 1988-12-07 1996-02-21 エスエス製薬株式会社 徐放性坐剤
US4906478A (en) 1988-12-12 1990-03-06 Valentine Enterprises, Inc. Simethicone/calcium silicate composition
US4984240A (en) 1988-12-22 1991-01-08 Codex Corporation Distributed switching architecture for communication module redundancy
US5006297A (en) 1989-02-22 1991-04-09 Acushnet Company Method of molding polyurethane covered golf balls
US4956182A (en) 1989-03-16 1990-09-11 Bristol-Myers Company Direct compression cholestyramine tablet and solvent-free coating therefor
NZ233403A (en) 1989-04-28 1992-09-25 Mcneil Ppc Inc Simulated capsule-like medicament
US4990535A (en) 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
US4992277A (en) 1989-08-25 1991-02-12 Schering Corporation Immediate release diltiazem formulation
EP0419410A3 (en) 1989-09-19 1991-08-14 Ciba-Geigy Ag Alkanophenones
US5362508A (en) 1989-09-20 1994-11-08 Nabisco, Inc. Process for preparing soft centers in food products
US5146730A (en) 1989-09-20 1992-09-15 Banner Gelatin Products Corp. Film-enrobed unitary-core medicament and the like
DK469989D0 (da) 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
US5223264A (en) 1989-10-02 1993-06-29 Cima Labs, Inc. Pediatric effervescent dosage form
US5178878A (en) 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
US5275822A (en) 1989-10-19 1994-01-04 Valentine Enterprises, Inc. Defoaming composition
JPH03139496A (ja) * 1989-10-25 1991-06-13 Sanshin Ind Co Ltd 船舶推進機
US5169645A (en) 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties
US5223266A (en) 1990-01-24 1993-06-29 Alza Corporation Long-term delivery device with early startup
DE4012114A1 (de) 1990-04-14 1991-10-17 Hauni Werke Koerber & Co Kg Vorrichtung zum ueberfuehren von stabfoermigen artikeln der tabakverarbeitenden industrie
US4983394A (en) 1990-05-03 1991-01-08 Warner-Lambert Company Flavor enhancing and medicinal taste masking agent
US4980169A (en) 1990-05-03 1990-12-25 Warner-Lambert Company Flavor enhancing and increasing efficacy of cough drops
US5213738A (en) 1990-05-15 1993-05-25 L. Perrigo Company Method for making a capsule-shaped tablet
US5089270A (en) 1990-05-15 1992-02-18 L. Perrigo Company Capsule-shaped tablet
US5075114A (en) 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
US5464631A (en) * 1990-06-27 1995-11-07 Warner-Lambert Company Encapsulated dosage forms
DE4025487A1 (de) 1990-08-08 1992-02-13 Korsch Maschfab Fuellgeraet fuer die matrizen einer tablettiermaschine
US5133892A (en) 1990-10-17 1992-07-28 Lever Brothers Company, Division Of Conopco, Inc. Machine dishwashing detergent tablets
US5538125A (en) 1990-11-05 1996-07-23 Mcneil-Ppc, Inc. Indexing and feeding systems for apparatus for gelatin coating tablets
US5436026A (en) 1990-11-05 1995-07-25 Mcneil-Ppc, Inc. Discharge and transfer system for apparatus for gelatin coating tablets
US5503673A (en) 1990-11-05 1996-04-02 Mcneil-Ppc, Inc Apparatus for dip coating product
US5228916A (en) 1990-11-05 1993-07-20 Mcneil-Ppc, Inc. Apparatus for creating a gelatin coating
US5177080A (en) 1990-12-14 1993-01-05 Bayer Aktiengesellschaft Substituted pyridyl-dihydroxy-heptenoic acid and its salts
US5098715A (en) 1990-12-20 1992-03-24 Burroughs Wellcome Co. Flavored film-coated tablet
US5782337A (en) 1991-01-15 1998-07-21 Raychem Corporation Conveyor belt system and heater utilizing said system
IT1245763B (it) 1991-02-11 1994-10-14 Gd Spa Dispositivo per il trasferimento di spezzoni di sigaretta da una macchina confezionatrice a doppio baco ad una macchina mettifiltro.
US5378475A (en) 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
NZ241613A (en) 1991-02-27 1993-06-25 Janssen Pharmaceutica Nv Highlighting intagliations in tablets
CA2061520C (en) 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
US5158728A (en) 1991-04-12 1992-10-27 Elizabeth-Hata International, Inc. Multi-layer medicinal tablet forming machine and method for using the same
US5286497A (en) 1991-05-20 1994-02-15 Carderm Capital L.P. Diltiazem formulation
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5190927A (en) 1991-07-09 1993-03-02 Merck & Co., Inc. High-glyceryl, low-acetyl gellan gum for non-brittle gels
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
US5326570A (en) 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
US5200191A (en) * 1991-09-11 1993-04-06 Banner Gelatin Products Corp. Softgel manufacturing process
DK171536B1 (da) 1991-12-06 1996-12-23 Rasmussen Kann Ind As Vindue med ramme af ekstruderede profilemner
US5200195A (en) 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
US5274162A (en) 1991-12-13 1993-12-28 Arnold Glazier Antineoplastic drugs with bipolar toxification/detoxification functionalities
GB2284760B (en) 1993-11-23 1998-06-24 Euro Celtique Sa A method of preparing pharmaceutical compositions by melt pelletisation
KR940703886A (ko) 1992-01-17 1994-12-12 토머스 디. 뵈닝 셀룰로오스 중합체 및 락토오스 기재 필름 코팅 조성물 및 필름 코팅(Film Coatings and Film Coating Compositions Based on Cellulosic Polymers and Lactose)
US5427614A (en) 1992-02-14 1995-06-27 Warner-Lambert Company Starch based formulations
US5421447A (en) 1992-04-07 1995-06-06 Omega Design Corp. High rate transfer wheel for orienting unscrambled containers
US5656296A (en) 1992-04-29 1997-08-12 Warner-Lambert Company Dual control sustained release drug delivery systems and methods for preparing same
EP0572731A1 (de) 1992-06-01 1993-12-08 The Procter & Gamble Company Kaubare Zusammensetzung enthaltend ein Dekongestirum
DE4218122C1 (de) 1992-06-02 1994-01-20 Fette Wilhelm Gmbh Verfahren zum Pressen von Zweischichttabletten in einer Doppelrundläuferpresse und Vorrichtung zur Durchführung des Verfahrens
WO1993024109A1 (en) 1992-06-04 1993-12-09 Smithkline Beecham Corporation Palatable pharmaceutical compositions
JPH0617096A (ja) 1992-07-01 1994-01-25 Asahi Glass Co Ltd 混合系溶剤組成物
US5317849A (en) 1992-08-07 1994-06-07 Sauter Manufacturing Corporation Encapsulation equipment and method
IT1255522B (it) 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
JPH07507564A (ja) 1992-09-30 1995-08-24 ファイザー・インク. コア及び厚さが一定でないコーティングを含有する物品
JP3380594B2 (ja) 1992-10-14 2003-02-24 エーザイ株式会社 薬液の送液ポンプとこれを用いる薬液の充填用送液装置
KR950703935A (ko) 1992-11-30 1995-11-17 밋첼 아이, 커시너 맛을 차단하는 약제학적 조성물
DE4243010C1 (de) 1992-12-19 1994-05-26 Kronseder Maschf Krones Packmaschine
TW272942B (de) 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd
US5391378A (en) * 1993-02-22 1995-02-21 Elizabeth-Hata International, Inc. Two-part medicinal tablet and method of manufacture
JP2524955B2 (ja) 1993-04-22 1996-08-14 トーワ株式会社 電子部品の樹脂封止成形方法及び装置
ES2149250T3 (es) 1993-04-23 2000-11-01 Novartis Ag Dispositivo para la administracion de medicamentos con liberacion controlada.
US5342626A (en) 1993-04-27 1994-08-30 Merck & Co., Inc. Composition and process for gelatin-free soft capsules
US5415868A (en) 1993-06-09 1995-05-16 L. Perrigo Company Caplets with gelatin cover and process for making same
IT1264855B1 (it) 1993-06-21 1996-10-17 Zambon Spa Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici
IT1264696B1 (it) 1993-07-09 1996-10-04 Applied Pharma Res Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata
ZA944949B (en) 1993-07-12 1995-04-05 Smithkline Beecham Corp Matrix-entrapped beadlet preparation
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5622719A (en) 1993-09-10 1997-04-22 Fuisz Technologies Ltd. Process and apparatus for making rapidly dissolving dosage units and product therefrom
US5648033A (en) 1993-09-10 1997-07-15 Fuisz Technologies Ltd. Method and apparatus for retaining a formed compression dosage unit within a die cavity
US5518551A (en) 1993-09-10 1996-05-21 Fuisz Technologies Ltd. Spheroidal crystal sugar and method of making
US5500227A (en) 1993-11-23 1996-03-19 Euro-Celtique, S.A. Immediate release tablet cores of insoluble drugs having sustained-release coating
DE4341442C2 (de) 1993-12-04 1998-11-05 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung
US5429226A (en) 1993-12-15 1995-07-04 Rexnord Corporation Conveyor chain for carrying objects
JPH07281423A (ja) 1994-04-07 1995-10-27 Konica Corp 印刷版の製版方法
JP3518556B2 (ja) 1994-05-11 2004-04-12 株式会社紀文食品 ゲル凝固食品
US5464633A (en) 1994-05-24 1995-11-07 Jagotec Ag Pharmaceutical tablets releasing the active substance after a definite period of time
US6020002A (en) 1994-06-14 2000-02-01 Fuisz Technologies Ltd. Delivery of controlled-release system(s)
US5672364A (en) 1994-07-07 1997-09-30 Sankyo Seisakusho Co. & Eisai Co., Ltd. Apparatus for manufacturing tablets
US5525179A (en) * 1994-07-18 1996-06-11 Empe-Werke Ernst Pelz Gmbh & Co. Kg Method of manufacturing a lining part
US5788979A (en) 1994-07-22 1998-08-04 Inflow Dynamics Inc. Biodegradable coating with inhibitory properties for application to biocompatible materials
IT1274034B (it) 1994-07-26 1997-07-14 Applied Pharma Res Composizioni farmaceutiche a base di gomma da masticare e procedimento per la loro preparazione
EP0773866B1 (de) * 1994-08-03 1998-04-08 Gunter Meinhardt Voss Verfahren zur herstellung von manteltabletten
DE9414065U1 (de) 1994-08-31 1994-11-03 Roehm Gmbh Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen
DE4431653C2 (de) 1994-09-06 2000-01-20 Lohmann Therapie Syst Lts Manteltablette zur kontrollierten Freisetzung von Wirkstoffen, ein Verfahren zu ihrer Herstellung und ihre Verwendung
US5614578A (en) * 1994-10-28 1997-03-25 Alza Corporation Injection-molded dosage form
US5756123A (en) 1994-12-01 1998-05-26 Japan Elanco Co., Ltd. Capsule shell
US5626896A (en) 1994-12-09 1997-05-06 A.E. Staley Manufacturing Co. Method for making liquid-centered jelly candies
DE4446468A1 (de) 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von umhüllten Tabletten
ES2124956T3 (es) 1995-02-07 1999-02-16 Hermann Kronseder Estrella de transporte para recipientes.
DE29502547U1 (de) * 1995-02-16 1995-03-30 Roehm Gmbh Thermoplastisches Überzugs- und Bindemittel für Arzneiformen
US5558879A (en) 1995-04-28 1996-09-24 Andrx Pharmaceuticals, Inc. Controlled release formulation for water soluble drugs in which a passageway is formed in situ
US5827874A (en) 1995-05-05 1998-10-27 Meyer; Hans Methods of treating pain and inflammation with proline
AU5655296A (en) 1995-05-09 1996-11-29 Colorcon Limited Electrostatic coating
DE59601245D1 (de) 1995-05-13 1999-03-18 Hermann Kronseder Transportstern für Gefässe
US5578336A (en) 1995-06-07 1996-11-26 Monte; Woodrow C. Confection carrier for vitamins, enzymes, phytochemicals and ailmentary vegetable compositions and method of making
US5614207A (en) 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge
GB9517031D0 (en) 1995-08-19 1995-10-25 Procter & Gamble Confection compositions
AUPN605795A0 (en) 1995-10-19 1995-11-09 F.H. Faulding & Co. Limited Analgesic pharmaceutical composition
DE19539361A1 (de) 1995-10-23 1997-04-24 Basf Ag Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung
IT1279673B1 (it) 1995-11-07 1997-12-16 Acma Spa Apparecchiatura e metodo per la formazione di gruppi ordinati di prodotti da alimentare a passo.
US5733578A (en) 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US5807579A (en) 1995-11-16 1998-09-15 F.H. Faulding & Co. Limited Pseudoephedrine combination pharmaceutical compositions
WO1997023765A1 (en) 1995-12-22 1997-07-03 A/S Brüel & Kjær A system and a method for measuring a continuous signal
US5813513A (en) 1995-12-26 1998-09-29 Redicon Corporation Conveyor apparatus
US5643984A (en) 1996-01-03 1997-07-01 Flint Ink Corporation New Wax composition for the printing ink industry and ink compositions and overprint varnishes containing same
US5879728A (en) 1996-01-29 1999-03-09 Warner-Lambert Company Chewable confectionary composition and method of preparing same
CN1137926A (zh) 1996-02-05 1996-12-18 杨满寿 带保护层的虫草及其制法
IT1282576B1 (it) 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
NL1003057C2 (nl) 1996-05-07 1997-11-10 Greefs Wagen Carrosserie Inrichting en werkwijze voor het aan-, afvoeren en overbrengen van voorwerpen, zoals vruchten.
US5711691A (en) * 1996-05-13 1998-01-27 Air Packaging Technologies, Inc. Self-closing and self-sealing valve device for use with inflatable structures
US5824338A (en) 1996-08-19 1998-10-20 L. Perrigo Company Caplet and gelatin covering therefor
US5916881A (en) 1996-10-07 1999-06-29 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo High trehalose content syrup
US6077539A (en) 1996-11-12 2000-06-20 Pozen, Inc. Treatment of migraine headache
GB9624110D0 (en) 1996-11-20 1997-01-08 Molins Plc Transferring rod like articles
FR2757173A1 (fr) 1996-12-17 1998-06-19 Warner Lambert Co Compositions polymeres d'origine non-animale pour la formation de films
US5827548A (en) 1997-01-14 1998-10-27 Lisco, Inc. Golf ball injection mold
US5996768A (en) 1997-01-22 1999-12-07 R. W. Hartnett Company Quick change drum
US5922352A (en) 1997-01-31 1999-07-13 Andrx Pharmaceuticals, Inc. Once daily calcium channel blocker tablet having a delayed release core
DE19710213A1 (de) 1997-03-12 1998-09-17 Basf Ag Verfahren zur Herstellung von festen Kombinationsarzneiformen
US5837301A (en) 1997-04-28 1998-11-17 Husky Injection Molding Systems Ltd. Injection molding machine having a high speed turret
US6210710B1 (en) 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
US6149939A (en) 1997-05-09 2000-11-21 Strumor; Mathew A. Healthful dissolvable oral tablets, and mini-bars
AU7755398A (en) 1997-06-25 1999-01-19 Ipr-Institute For Pharmaceutical Research Ag Method for reducing body weight
WO1999002136A1 (de) 1997-07-09 1999-01-21 Peter Greither Verfahren und vorrichtung zum herstellen einer mehrschichtigen, physiologisch verträglichen darreichungsform
US6103260A (en) 1997-07-17 2000-08-15 Mcneil-Ppc, Inc. Simethicone/anhydrous calcium phosphate compositions
US5942034A (en) 1997-07-24 1999-08-24 Bayer Corporation Apparatus for the gelatin coating of medicaments
US5840334A (en) 1997-08-20 1998-11-24 Fuisz Technologies Ltd. Self-binding shearform compositions
WO1999022769A1 (en) 1997-10-31 1999-05-14 Monsanto Company Gellan gum tablet coating
CN100379407C (zh) 1997-12-19 2008-04-09 史密丝克莱恩比彻姆公司 生产咀嚼分散片的方法
CA2303852C (en) 1997-12-26 2008-03-18 Warner-Lambert Company Fish gelatin compositions containing a hydrocolloid setting system
US5962053A (en) 1998-02-17 1999-10-05 Viskase Corporation Edible film and method
US6432442B1 (en) 1998-02-23 2002-08-13 Mcneil-Ppc, Inc. Chewable product
US6099859A (en) 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
US6365185B1 (en) 1998-03-26 2002-04-02 University Of Cincinnati Self-destructing, controlled release peroral drug delivery system
US6372254B1 (en) 1998-04-02 2002-04-16 Impax Pharmaceuticals Inc. Press coated, pulsatile drug delivery system suitable for oral administration
FR2778135B1 (fr) * 1998-04-30 2000-07-07 Plastic Omnium Cie Procede pour realiser une piece en matiere plastique partiellement revetue d'un film, notamment decoratif
US6394094B1 (en) 1998-05-01 2002-05-28 Enhance Pharmaceuticals, Inc. Method for injection molding manufacture of controlled release devices
US6365183B1 (en) 1998-05-07 2002-04-02 Alza Corporation Method of fabricating a banded prolonged release active agent dosage form
AU748359B2 (en) 1998-05-15 2002-06-06 Chugai Seiyaku Kabushiki Kaisha Controlled-release formulations
EP1449524A1 (de) 1998-06-03 2004-08-25 ALZA Corporation Methode und Vorrichtung zur Erreichung einer verlängerten Medikamententherapie
US6106267A (en) * 1998-06-05 2000-08-22 Aylward; John T. Apparatus for forming a compression-molded product
ES2157726B1 (es) 1998-06-12 2002-03-01 Bonals S A J Perfeccionamientos en las maquinas rotativas para la fabricacion de comprimidos.
US6103257A (en) 1998-07-17 2000-08-15 Num-Pop, Inc. System for delivering pharmaceuticals to the buccal mucosa
DE19834180A1 (de) 1998-07-29 2000-02-03 Benckiser Nv Zusammensetzung zur Verwendung in einer Geschirrspülmaschine
US6200590B1 (en) 1998-08-10 2001-03-13 Naphcare, Inc. Controlled, phased-release suppository and its method of production
US6270790B1 (en) 1998-08-18 2001-08-07 Mxneil-Ppc, Inc. Soft, convex shaped chewable tablets having reduced friability
DE19840256A1 (de) * 1998-09-03 2000-03-09 Basf Ag Verfahren zur Herstellung von beschichteten festen Dosierungsformen
US5997905A (en) 1998-09-04 1999-12-07 Mcneil-Ppc Preparation of pharmaceutically active particles
US6174547B1 (en) 1999-07-14 2001-01-16 Alza Corporation Dosage form comprising liquid formulation
US6602521B1 (en) 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
DE19847618A1 (de) * 1998-10-15 2000-04-20 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
US6322819B1 (en) 1998-10-21 2001-11-27 Shire Laboratories, Inc. Oral pulsed dose drug delivery system
US6485747B1 (en) 1998-10-30 2002-11-26 Monsanto Company Coated active tablet(s)
US6165512A (en) 1998-10-30 2000-12-26 Fuisz Technologies Ltd. Dosage forms containing taste masked active agents
US6482349B1 (en) * 1998-11-02 2002-11-19 Sumitomo Special Metals Co., Ltd. Powder pressing apparatus and powder pressing method
JP3193912B2 (ja) * 1998-11-02 2001-07-30 住友特殊金属株式会社 粉体プレス装置および粉体プレス方法
US6270805B1 (en) 1998-11-06 2001-08-07 Andrx Pharmaceuticals, Inc. Two pellet controlled release formulation for water soluble drugs which contains an alkaline metal stearate
DE19853985A1 (de) * 1998-11-23 2000-05-25 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
US6405853B1 (en) 1998-11-24 2002-06-18 Steven T. Cook Conveyor system for can end conversion systems
US6183681B1 (en) * 1998-12-07 2001-02-06 Centurion International, Inc. Multi-stage insert molding method
DE19901383A1 (de) * 1999-01-15 2000-07-20 Knoll Ag Verfahren zur Herstellung unterschiedlicher fester Dosierungsformen
US6276917B1 (en) 1999-01-28 2001-08-21 Botanicals International Powder processing apparatus
EP1029892B1 (de) 1999-02-10 2002-06-05 Dr. Suwelack Skin & Health Care AG Beta-1,3-Glucan aus Euglena enthaltendes gefriergetrocknetes Erzeugnis, seine Herstellung und Verwendung
US6274162B1 (en) 2000-01-14 2001-08-14 Bpsi Holdings, Inc. Elegant film coating system
US6248760B1 (en) 1999-04-14 2001-06-19 Paul C Wilhelmsen Tablet giving rapid release of nicotine for transmucosal administration
JP2001072579A (ja) 1999-06-29 2001-03-21 Taisho Pharmaceut Co Ltd 有核錠及びその製造方法並びに製造システム
WO2001000179A1 (fr) 1999-06-29 2001-01-04 Taisho Pharmaceutical Co., Ltd. Comprime enrobe a sec, et procede et systeme de production de celui-ci
DE19941997A1 (de) 1999-09-02 2001-03-08 Gunther Meinhardt Voss Verfahren und Vorrichtung zur Herstellung einer Tablette o. dgl.
GB9921933D0 (en) 1999-09-17 1999-11-17 Univ Gent Solid shaped articles comprising biologically active substances and a method for their production
AU1195001A (en) 1999-10-11 2001-04-23 Monsanto Company Tablets coated with locust bean gum, guar gum or carrageenan gum
DE19954420A1 (de) 1999-11-12 2001-05-31 Lohmann Therapie Syst Lts Zubereitung, bestehend aus einer film-, folien- oder oblatenförmigen Darreichungsform mit zweischichtigem Aufbau und integrierter Kennzeichnung
DE19960494A1 (de) 1999-12-15 2001-06-21 Knoll Ag Vorrichtung und Verfahren zum Herstellen von festen wirkstoffhaltigen Formen
DE19963569B4 (de) 1999-12-29 2006-11-16 Reckitt Benckiser N.V. Zusammensetzung zur Verwendung in einer Geschirrspülmaschine
WO2001056550A1 (en) 2000-02-01 2001-08-09 Monsanto Company Gellan gum dipped products
US20020028240A1 (en) 2000-04-17 2002-03-07 Toyohiro Sawada Timed-release compression-coated solid composition for oral administration
US6499984B1 (en) * 2000-05-22 2002-12-31 Warner-Lambert Company Continuous production of pharmaceutical granulation
WO2002019833A2 (en) 2000-09-07 2002-03-14 Akpharma Inc. Edible candy compositions and methods of using the same
WO2002058667A2 (en) * 2001-01-26 2002-08-01 Bausch & Lomb Incorporated Improved process for the production of sustained release drug delivery devices
US6558722B2 (en) 2001-07-18 2003-05-06 Wm. Wrigley Jr. Company Use of powdered gum in making a coating for a confection
GB0120835D0 (en) 2001-08-28 2001-10-17 Smithkline Beecham Plc Process
US6837696B2 (en) 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US6742646B2 (en) 2001-09-28 2004-06-01 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6767200B2 (en) 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7217381B2 (en) * 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7323192B2 (en) 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
WO2003063831A2 (en) 2002-02-01 2003-08-07 Pfizer Products Inc. Immediate release dosage forms containing solid drug dispersions

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CN1635863A (zh) 2005-07-06
US20120074614A1 (en) 2012-03-29
EP1432378B1 (de) 2008-12-31
US8673190B2 (en) 2014-03-18
US8114328B2 (en) 2012-02-14
EP1432378A1 (de) 2004-06-30
US20050008696A1 (en) 2005-01-13
JP2005504589A (ja) 2005-02-17
KR20040039459A (ko) 2004-05-10
WO2003028619A2 (en) 2003-04-10
CA2461873A1 (en) 2003-04-10
CA2461873C (en) 2012-10-30
MXPA04002969A (es) 2005-06-20
US7122143B2 (en) 2006-10-17
ATE418953T1 (de) 2009-01-15
US20030086973A1 (en) 2003-05-08

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