DE60235646D1 - Reiterative oligonukleotidsynthese nutzende molekulare nachweissysteme - Google Patents
Reiterative oligonukleotidsynthese nutzende molekulare nachweissystemeInfo
- Publication number
- DE60235646D1 DE60235646D1 DE60235646T DE60235646T DE60235646D1 DE 60235646 D1 DE60235646 D1 DE 60235646D1 DE 60235646 T DE60235646 T DE 60235646T DE 60235646 T DE60235646 T DE 60235646T DE 60235646 D1 DE60235646 D1 DE 60235646D1
- Authority
- DE
- Germany
- Prior art keywords
- oligonucleotide
- detecting
- molecular
- oligonucleotide synthesis
- refrigeration systems
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/984,664 US7045319B2 (en) | 2001-10-30 | 2001-10-30 | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
PCT/US2002/034419 WO2003038042A2 (en) | 2001-10-30 | 2002-10-29 | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60235646D1 true DE60235646D1 (de) | 2010-04-22 |
Family
ID=25530752
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60235646T Expired - Lifetime DE60235646D1 (de) | 2001-10-30 | 2002-10-29 | Reiterative oligonukleotidsynthese nutzende molekulare nachweissysteme |
Country Status (8)
Country | Link |
---|---|
US (7) | US7045319B2 (de) |
EP (1) | EP1451366B1 (de) |
JP (1) | JP2006507792A (de) |
AT (1) | ATE460499T1 (de) |
AU (1) | AU2002360306A1 (de) |
CA (1) | CA2465158C (de) |
DE (1) | DE60235646D1 (de) |
WO (1) | WO2003038042A2 (de) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040054162A1 (en) * | 2001-10-30 | 2004-03-18 | Hanna Michelle M. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
US7045319B2 (en) * | 2001-10-30 | 2006-05-16 | Ribomed Biotechnologies, Inc. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
DK1342794T3 (da) * | 2002-03-05 | 2006-04-24 | Epigenomics Ag | Fremgangsmåde og anordning til at bestemme vævsspecificitet af fritflydende DNA i legemsvæsker |
AU2003903430A0 (en) * | 2003-07-04 | 2003-07-17 | Johnson & Johnson Research Pty Limited | Method for detection of alkylated cytosine in dna |
JP5590757B2 (ja) * | 2003-09-17 | 2014-09-17 | キヤノン株式会社 | 安定なハイブリッド体 |
US7964344B2 (en) | 2003-09-17 | 2011-06-21 | Canon Kabushiki Kaisha | Stable hybrid |
EP1692263A4 (de) * | 2003-10-29 | 2008-01-02 | Ribomed Biotechnologies Inc | Zusammensetzungen, verfahren und nachweistechnologien zur reiterativen oligonukleotidsynthese |
US8158347B2 (en) | 2004-09-27 | 2012-04-17 | The University Of North Carolina At Chapel Hill | Determination of molecular age by detection of INK4a/ARF expression |
US20070111216A1 (en) * | 2004-09-27 | 2007-05-17 | Epicentre Technologies | Methods for identifying polymerase inhibitors |
JP2006094807A (ja) * | 2004-09-30 | 2006-04-13 | Nissan Motor Co Ltd | 情報化核酸担持微粒子及びその製造方法 |
JP2006094814A (ja) * | 2004-09-30 | 2006-04-13 | Nissan Motor Co Ltd | 情報化核酸及びこれを用いた情報化核酸組成物 |
JP4674794B2 (ja) * | 2004-12-15 | 2011-04-20 | 日産自動車株式会社 | クリヤー塗料組成物及びクリヤー塗膜 |
JP2006169332A (ja) * | 2004-12-15 | 2006-06-29 | Nissan Motor Co Ltd | 着色上塗り塗料組成物及び着色上塗り塗膜 |
US9505846B2 (en) | 2005-01-28 | 2016-11-29 | Life Technologies Corporation | Multi-component inhibitors of nucleic acid polymerases |
WO2007102891A2 (en) * | 2005-11-08 | 2007-09-13 | Euclid Diagnostics Llc | Materials and methods for assaying for methylation of cpg islands associated with genes in the evaluation of cancer |
US7772390B1 (en) | 2006-07-18 | 2010-08-10 | The Regents Of The University Of California | Lipid mediated nucleic acid synthesis |
US7501254B2 (en) | 2006-07-20 | 2009-03-10 | Ghc Technologies, Inc. | Methods and compositions for amplification and capture of nucleic acid sequences |
US20080160638A1 (en) * | 2006-12-27 | 2008-07-03 | David Lederman | Functionalized Microcantilever Sensor and Associated Method For Detection of Targeted Analytes |
US8906354B2 (en) | 2007-02-28 | 2014-12-09 | Bruker Biospin Corporation | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes |
US8017104B2 (en) * | 2007-02-28 | 2011-09-13 | Carestream Health, Inc. | Large stoke shift dye used for optical imaging |
US7906316B2 (en) * | 2007-07-05 | 2011-03-15 | The Johns Hopkins University | Apparatus for detecting molecules |
US20090137024A1 (en) * | 2007-11-28 | 2009-05-28 | Canon U.S. Life Sciences, Inc. | Method of Separating Target DNA from Mixed DNA |
US20090162845A1 (en) | 2007-12-20 | 2009-06-25 | Elazar Rabbani | Affinity tag nucleic acid and protein compositions, and processes for using same |
US8242243B2 (en) * | 2008-05-15 | 2012-08-14 | Ribomed Biotechnologies, Inc. | Methods and reagents for detecting CpG methylation with a methyl CpG binding protein (MBP) |
EP2235177B1 (de) * | 2008-06-13 | 2012-07-18 | RiboxX GmbH | Verfahren zur enzymatischen synthese chemisch modifizierter rna |
WO2010009060A2 (en) * | 2008-07-13 | 2010-01-21 | Ribomed Biotechnologies, Inc. | Molecular beacon-based methods for detection of targets using abscription |
EP2380020A2 (de) | 2008-12-18 | 2011-10-26 | The Texas A&M University System | Ph-modulationsverfahren zum nachweis von liganden-rezeptor-bindung |
WO2010080617A2 (en) | 2008-12-19 | 2010-07-15 | The Board Of Trustees Of The University Of Illinois | Detecting and sorting methylated dna using a synthetic nanopore |
SG172345A1 (en) | 2008-12-22 | 2011-07-28 | Celula Inc | Methods and genotyping panels for detecting alleles, genomes, and transcriptomes |
JP2012520086A (ja) * | 2009-03-15 | 2012-09-06 | リボムド バイオテクノロジーズ インク | アブスクリプションに基づく分子検出 |
EP2280080A1 (de) * | 2009-07-31 | 2011-02-02 | Qiagen GmbH | Verfahren zur standardisierten Quantifizierung von Nukleinsäuren unter Verwendung von Anker-Oligonukleotiden und Adapter-Oligonukleotiden |
US9034658B2 (en) * | 2009-11-23 | 2015-05-19 | The General Hospital Corporation | Microfluidic devices for the capture of biological sample components |
US8748091B2 (en) * | 2009-12-18 | 2014-06-10 | The Board Of Trustees Of The University Of Illinois | Characterizing stretched polynucleotides in a synthetic nanopassage |
BR112012025165B1 (pt) * | 2010-04-02 | 2021-02-09 | Pharmacophotonics, Inc. | composição de um corante de rodamina ou um sal do mesmo |
CN103038361B (zh) | 2010-05-14 | 2017-02-08 | 西森斯公司 | 试剂盒和方法 |
WO2012075313A2 (en) | 2010-12-01 | 2012-06-07 | The Texas A&M University System | Ph modulation methods and systems for detecting binding events |
HUE049669T2 (hu) | 2011-02-11 | 2020-10-28 | Univ Pennsylvania | Hepatitis B vírus magfehérjéjét kódoló nukleinsav-molekula és azt tartalmazó oltóanyag |
GB201112622D0 (en) * | 2011-07-22 | 2011-09-07 | Ucl Business Plc | Pathogen screening |
US20150011396A1 (en) | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
US20140127698A1 (en) * | 2012-11-02 | 2014-05-08 | Life Technologies Corporation | Reiterative oligonucleotide synthesis |
US20160153973A1 (en) * | 2013-07-09 | 2016-06-02 | Lucas David Smith | Device and method of rapid linker mediated label-based immunoassays |
WO2019079579A1 (en) * | 2017-10-20 | 2019-04-25 | Nugen Technologies, Inc. | OLIGONUCLEOTIDES FOR SELECTIVE AMPLIFICATION OF NUCLEIC ACIDS |
AU2020407267A1 (en) * | 2019-12-18 | 2022-06-16 | F. Hoffmann-La Roche Ag | Methods of sequencing by synthesis using a consecutive labeling scheme |
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DE2345412C2 (de) * | 1973-09-08 | 1983-11-03 | Bomag-Menck GmbH, 5407 Boppard | Zweiachsige Straßenwalze |
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US4351760A (en) | 1979-09-07 | 1982-09-28 | Syva Company | Novel alkyl substituted fluorescent compounds and polyamino acid conjugates |
US4582788A (en) | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
US4786600A (en) | 1984-05-25 | 1988-11-22 | The Trustees Of Columbia University In The City Of New York | Autocatalytic replication of recombinant RNA |
US5503979A (en) * | 1984-05-25 | 1996-04-02 | The Trustees Of Columbia University In The City Of New York | Method of using replicatable hybridzable recombinant RNA probes |
US4683194A (en) | 1984-05-29 | 1987-07-28 | Cetus Corporation | Method for detection of polymorphic restriction sites and nucleic acid sequences |
US4739044A (en) | 1985-06-13 | 1988-04-19 | Amgen | Method for derivitization of polynucleotides |
US4757141A (en) | 1985-08-26 | 1988-07-12 | Applied Biosystems, Incorporated | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof |
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US7045319B2 (en) | 2001-10-30 | 2006-05-16 | Ribomed Biotechnologies, Inc. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
US20040054162A1 (en) | 2001-10-30 | 2004-03-18 | Hanna Michelle M. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
EP1692263A4 (de) | 2003-10-29 | 2008-01-02 | Ribomed Biotechnologies Inc | Zusammensetzungen, verfahren und nachweistechnologien zur reiterativen oligonukleotidsynthese |
-
2001
- 2001-10-30 US US09/984,664 patent/US7045319B2/en not_active Expired - Fee Related
-
2002
- 2002-10-29 AU AU2002360306A patent/AU2002360306A1/en not_active Abandoned
- 2002-10-29 EP EP02795555A patent/EP1451366B1/de not_active Expired - Lifetime
- 2002-10-29 US US10/488,971 patent/US7470511B2/en not_active Expired - Fee Related
- 2002-10-29 JP JP2003540307A patent/JP2006507792A/ja active Pending
- 2002-10-29 DE DE60235646T patent/DE60235646D1/de not_active Expired - Lifetime
- 2002-10-29 AT AT02795555T patent/ATE460499T1/de active
- 2002-10-29 CA CA2465158A patent/CA2465158C/en not_active Expired - Fee Related
- 2002-10-29 WO PCT/US2002/034419 patent/WO2003038042A2/en active Application Filing
-
2003
- 2003-06-23 US US10/600,581 patent/US7541165B2/en not_active Expired - Fee Related
- 2003-06-24 US US10/602,045 patent/US7468261B2/en not_active Expired - Fee Related
- 2003-06-27 US US10/607,136 patent/US7226738B2/en not_active Expired - Fee Related
- 2003-10-17 US US10/686,713 patent/US20040175724A1/en not_active Abandoned
-
2004
- 2004-03-03 US US10/790,766 patent/US7473775B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20050064414A1 (en) | 2005-03-24 |
US20030099950A1 (en) | 2003-05-29 |
EP1451366B1 (de) | 2010-03-10 |
US20040234996A1 (en) | 2004-11-25 |
US20040175724A1 (en) | 2004-09-09 |
WO2003038042A3 (en) | 2004-03-25 |
ATE460499T1 (de) | 2010-03-15 |
JP2006507792A (ja) | 2006-03-09 |
WO2003038042A2 (en) | 2003-05-08 |
US7468261B2 (en) | 2008-12-23 |
US7045319B2 (en) | 2006-05-16 |
AU2002360306A1 (en) | 2003-05-12 |
US7473775B2 (en) | 2009-01-06 |
US7541165B2 (en) | 2009-06-02 |
US20040157257A1 (en) | 2004-08-12 |
CA2465158C (en) | 2013-01-22 |
US7226738B2 (en) | 2007-06-05 |
US20040137461A1 (en) | 2004-07-15 |
EP1451366A2 (de) | 2004-09-01 |
US20050026150A1 (en) | 2005-02-03 |
CA2465158A1 (en) | 2003-05-08 |
EP1451366A4 (de) | 2006-09-13 |
US7470511B2 (en) | 2008-12-30 |
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Legal Events
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8364 | No opposition during term of opposition |