DE60322044D1 - Rekombinase-polymerase-amplifikation - Google Patents
Rekombinase-polymerase-amplifikationInfo
- Publication number
- DE60322044D1 DE60322044D1 DE60322044T DE60322044T DE60322044D1 DE 60322044 D1 DE60322044 D1 DE 60322044D1 DE 60322044 T DE60322044 T DE 60322044T DE 60322044 T DE60322044 T DE 60322044T DE 60322044 D1 DE60322044 D1 DE 60322044D1
- Authority
- DE
- Germany
- Prior art keywords
- dna
- amplification
- polymerase amplification
- recombinase polymerase
- recombinase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/90—Details of database functions independent of the retrieved data types
- G06F16/95—Retrieval from the web
- G06F16/951—Indexing; Web crawling techniques
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/90—Details of database functions independent of the retrieved data types
- G06F16/95—Retrieval from the web
- G06F16/957—Browsing optimisation, e.g. caching or content distillation
- G06F16/9574—Browsing optimisation, e.g. caching or content distillation of access to content, e.g. by caching
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35856302P | 2002-02-21 | 2002-02-21 | |
| PCT/US2003/005492 WO2003072805A2 (en) | 2002-02-21 | 2003-02-21 | Recombinase polymerase amplification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60322044D1 true DE60322044D1 (de) | 2008-08-21 |
Family
ID=27765964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60322044T Expired - Lifetime DE60322044D1 (de) | 2002-02-21 | 2003-02-21 | Rekombinase-polymerase-amplifikation |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US7270981B2 (de) |
| EP (4) | EP2290096B1 (de) |
| JP (4) | JP4340543B2 (de) |
| AT (1) | ATE400663T1 (de) |
| AU (1) | AU2003215391B2 (de) |
| CA (1) | CA2476481C (de) |
| DE (1) | DE60322044D1 (de) |
| DK (1) | DK1499738T3 (de) |
| ES (1) | ES2310237T3 (de) |
| PT (1) | PT1499738E (de) |
| WO (1) | WO2003072805A2 (de) |
Families Citing this family (150)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1386006B1 (de) * | 2001-04-20 | 2008-05-28 | The Penn State Research Foundation | Verfahren zur manipulation von nukleinsäuren |
| ATE400663T1 (de) * | 2002-02-21 | 2008-07-15 | Asm Scient Inc | Rekombinase-polymerase-amplifikation |
| US8030000B2 (en) | 2002-02-21 | 2011-10-04 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| US7282328B2 (en) * | 2002-09-20 | 2007-10-16 | New England Biolabs, Inc. | Helicase dependent amplification of nucleic acids |
| WO2004092330A2 (en) * | 2003-04-11 | 2004-10-28 | Applera Corporation | Method of generating long nucleic acid molecules of defined sequence |
| JP2005110621A (ja) * | 2003-10-10 | 2005-04-28 | Aisin Seiki Co Ltd | 核酸増幅方法及び核酸増幅用試薬キット |
| ES2718482T3 (es) * | 2004-06-01 | 2019-07-02 | Alere San Diego Inc | Kit para amplificación de recombinasa polimerasa |
| AU2011202896B2 (en) * | 2004-06-01 | 2012-12-06 | Abbott Diagnostics Scarborough, Inc. | Recombinase Polymerase Amplification |
| US7759061B2 (en) | 2004-06-02 | 2010-07-20 | Twistdx, Inc. | 2′-nitrobenzyl-modified ribonucleotides |
| JP4534138B2 (ja) * | 2004-12-21 | 2010-09-01 | アイシン精機株式会社 | 核酸増幅反応における高度好熱菌由来タンパク質の活性化方法およびその利用 |
| EP1841879A4 (de) * | 2005-01-25 | 2009-05-27 | Population Genetics Technologi | Isothermische dna-amplifikation |
| EP2385140B1 (de) | 2005-07-25 | 2014-07-16 | Alere San Diego, Inc. | Verfahren zur Multiplexierung einer Rekombinase-Polymerase-Verstärkung |
| WO2007087262A2 (en) * | 2006-01-23 | 2007-08-02 | Population Genetics Technologies Ltd. | Selective genome amplification |
| JP2009535053A (ja) | 2006-05-04 | 2009-10-01 | エーエスエム サイエンティフィック， インコーポレイテッド | レコンビナーゼポリメラーゼ増幅 |
| US9061901B2 (en) | 2006-07-19 | 2015-06-23 | Bionano Genomics, Inc. | Nanonozzle device arrays: their preparation and use for macromolecular analysis |
| CN103305402A (zh) | 2007-03-28 | 2013-09-18 | 博纳基因技术有限公司 | 使用纳米通道阵列的大分子分析方法 |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| US20090215050A1 (en) | 2008-02-22 | 2009-08-27 | Robert Delmar Jenison | Systems and methods for point-of-care amplification and detection of polynucleotides |
| AU2009267086B2 (en) * | 2008-06-30 | 2016-01-14 | Bionano Genomics, Inc. | Methods and devices for single-molecule whole genome analysis |
| WO2010003132A1 (en) | 2008-07-02 | 2010-01-07 | Illumina Cambridge Ltd. | Using populations of beads for the fabrication of arrays on surfaces |
| CN102292454B (zh) | 2008-11-18 | 2014-11-26 | 博纳基因技术有限公司 | 多核苷酸作图和测序 |
| EA020593B1 (ru) | 2009-01-13 | 2014-12-30 | Флуидигм Корпорейшн | Анализ нуклеиновых кислот, полученных из единичных клеток |
| WO2010091111A1 (en) | 2009-02-03 | 2010-08-12 | Biohelix Corporation | Endonuclease-enhanced helicase-dependent amplification |
| US9309557B2 (en) * | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Nucleic acid amplification |
| US9334531B2 (en) | 2010-12-17 | 2016-05-10 | Life Technologies Corporation | Nucleic acid amplification |
| US9309566B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Methods, compositions, systems, apparatuses and kits for nucleic acid amplification |
| US20100299773A1 (en) * | 2009-05-20 | 2010-11-25 | Monsanto Technology Llc | Methods and compositions for selecting an improved plant |
| WO2010135310A1 (en) | 2009-05-20 | 2010-11-25 | Biosite Incorporated | Dna glycosylase/lyase and ap endonuclease substrates |
| EP3360974A1 (de) | 2009-06-05 | 2018-08-15 | Alere San Diego, Inc. | Reagentien zur rekombinase polymerase amplifikation |
| EP2440659B1 (de) * | 2009-06-10 | 2016-11-16 | Wisconsin Alumni Research Foundation | Verfahren zur in-vitro-reparatur von dna-doppelstrang-brüchen und anwendung |
| NO329699B1 (no) * | 2009-06-16 | 2010-12-06 | Agr Cannseal As | Brønnverktøy og fremgangsmåte for in situ innføring av et behandlingsfluid i et ringrom i en brønn |
| US8951733B2 (en) | 2009-10-16 | 2015-02-10 | Monsanto Technology Llc | Methods of polynucleotide detection |
| GB0922097D0 (en) | 2009-12-17 | 2010-02-03 | Atlas Genetics Ltd | Microbial assay |
| US8759037B2 (en) | 2010-02-23 | 2014-06-24 | Illumina Cambridge Limited | Amplification methods to minimise sequence specific bias |
| US9399217B2 (en) | 2010-10-04 | 2016-07-26 | Genapsys, Inc. | Chamber free nanoreactor system |
| US9184099B2 (en) | 2010-10-04 | 2015-11-10 | The Board Of Trustees Of The Leland Stanford Junior University | Biosensor devices, systems and methods therefor |
| WO2012047889A2 (en) | 2010-10-04 | 2012-04-12 | Genapsys Inc. | Systems and methods for automated reusable parallel biological reactions |
| CN103270173B (zh) | 2010-10-12 | 2017-11-21 | 孟山都技术公司 | 对应于转基因事件mon87712的大豆植物和种子及其检测方法 |
| EP3564392B1 (de) | 2010-12-17 | 2021-11-24 | Life Technologies Corporation | Verfahren für nukleinsäureamplifikation |
| EP4059342A1 (de) | 2010-12-17 | 2022-09-21 | Monsanto Technology LLC | Verfahren zur verbesserung der kompetenz von pflanzenzellen |
| EP3978620A1 (de) | 2011-04-07 | 2022-04-06 | Abbott Diagnostics Scarborough, Inc. | Überwachung von rekombinase-polymerase-verstärkungsmischungen |
| US10172305B2 (en) | 2011-04-29 | 2019-01-08 | Monsanto Technology Llc | Diagnostic molecular markers for seed lot purity traits in soybeans |
| AU2012250879B2 (en) | 2011-05-02 | 2017-06-08 | Nutech Ventures | Plants with useful traits and related methods |
| US9926596B2 (en) | 2011-05-27 | 2018-03-27 | Genapsys, Inc. | Systems and methods for genetic and biological analysis |
| US8585973B2 (en) | 2011-05-27 | 2013-11-19 | The Board Of Trustees Of The Leland Stanford Junior University | Nano-sensor array |
| CA2837486C (en) | 2011-05-27 | 2020-10-27 | Genapsys, Inc. | Systems and methods for nucleic acid sequencing |
| JP6223332B2 (ja) | 2011-06-30 | 2017-11-01 | モンサント テクノロジー エルエルシー | 形質転換事象ｋｋ１７９−２に対応するアルファルファ植物および種子、ならびにその検出方法 |
| WO2013012440A2 (en) * | 2011-07-21 | 2013-01-24 | Cornell University | Methods and devices for dna sequencing and molecular diagnostics |
| WO2013033611A1 (en) | 2011-08-31 | 2013-03-07 | Monsanto Technology Llc | Methods and compositions for watermelon firmness |
| US9352312B2 (en) | 2011-09-23 | 2016-05-31 | Alere Switzerland Gmbh | System and apparatus for reactions |
| EP2785868B1 (de) | 2011-12-01 | 2017-04-12 | Genapsys Inc. | Systeme und verfahren für hocheffiziente elektronische sequenzierung und nachweis |
| JP5958034B2 (ja) * | 2012-04-11 | 2016-07-27 | 富士レビオ株式会社 | 分子ビーコン型プローブを用いた標的核酸の検出方法 |
| CN116064734A (zh) | 2012-04-19 | 2023-05-05 | 生命技术公司 | 核酸扩增 |
| EP2839026B1 (de) | 2012-04-19 | 2016-08-10 | Life Technologies Corporation | Nukleinsäureamplifikation |
| EP2859111B1 (de) | 2012-06-08 | 2020-07-08 | Ionian Technologies, LLC | Nukleinsäureamplifizierungen |
| DE102012014981B3 (de) * | 2012-07-26 | 2013-07-18 | Sartorius Stedim Biotech Gmbh | Verfahren zur Differenzierung zwischen lebenden und toten Zellen |
| EP2888371B1 (de) | 2012-08-24 | 2017-08-02 | Life Technologies Corporation | Verfahren, zusammensetzungen, systeme, vorrichtungen und kits für nukleinsäuresequenzierung mit gepaartem ende |
| EP3257952B1 (de) | 2012-09-11 | 2020-02-12 | Life Technologies Corporation | Nukleinsäureamplifikation |
| WO2014043143A1 (en) | 2012-09-11 | 2014-03-20 | Life Technologies Corporation | Nucleic acid amplification |
| US10314253B2 (en) | 2012-12-04 | 2019-06-11 | Seminis Vegetable Seeds, Inc. | Methods and compositions for watermelon sex expression |
| SG11201507272RA (en) | 2013-03-15 | 2015-10-29 | Theranos Inc | Nuclei acid amplification |
| US9809852B2 (en) | 2013-03-15 | 2017-11-07 | Genapsys, Inc. | Systems and methods for biological analysis |
| US9290800B2 (en) | 2013-03-15 | 2016-03-22 | Pacific Biosciences Of California, Inc. | Targeted rolling circle amplification |
| US9416387B2 (en) | 2013-03-15 | 2016-08-16 | Theranos, Inc. | Nucleic acid amplification |
| US10294489B2 (en) | 2013-03-15 | 2019-05-21 | Board Of Trustees Of Southern Illinois University | Soybean resistant to cyst nematodes |
| US10450595B2 (en) | 2013-03-15 | 2019-10-22 | Theranos Ip Company, Llc | Nucleic acid amplification |
| SG11201507261WA (en) | 2013-03-15 | 2015-10-29 | Theranos Inc | Nucleic acid amplification |
| US10059999B2 (en) | 2013-06-10 | 2018-08-28 | Monsanto Technology Llc | Molecular markers associated with soybean tolerance to low iron growth conditions |
| US20150132743A1 (en) | 2013-09-04 | 2015-05-14 | Fluidigm Corporation | Proximity assays for detecting nucleic acids and proteins in a single cell |
| CN103421777B (zh) * | 2013-09-11 | 2015-05-13 | 北京市农林科学院林业果树研究所 | 无需pcr仪的侧翼核酸序列快速准确扩增方法及应用 |
| US10767188B2 (en) | 2013-09-25 | 2020-09-08 | Nutech Ventures | Methods and compositions for obtaining useful plant traits |
| EP3054764B1 (de) | 2013-10-09 | 2018-12-05 | Monsanto Technology LLC | Transgenes ereignis mon87403 in mais und nachweisverfahren dafür |
| MX367192B (es) | 2013-10-30 | 2019-08-08 | Green Life Biotech Llc | Sistemas de cuantificacion de patogenesis y metodos de tratamiento para el enverdecimiento de los citricos. |
| NZ728726A (en) | 2013-11-27 | 2018-09-28 | Seminis Vegetable Seeds Inc | Disease resistance loci in onion |
| US10125393B2 (en) | 2013-12-11 | 2018-11-13 | Genapsys, Inc. | Systems and methods for biological analysis and computation |
| US20170009288A1 (en) | 2014-02-03 | 2017-01-12 | Thermo Fisher Scientific Baltics Uab | Method for controlled dna fragmentation |
| CN106231893B (zh) | 2014-02-21 | 2019-10-18 | 先正达参股股份有限公司 | 与玉米增加的能育性相关的遗传基因座 |
| NZ630710A (en) | 2014-02-27 | 2016-03-31 | Seminis Vegetable Seeds Inc | Compositions and methods for peronospora resistance in spinach |
| US9822401B2 (en) | 2014-04-18 | 2017-11-21 | Genapsys, Inc. | Methods and systems for nucleic acid amplification |
| GB201410022D0 (en) * | 2014-06-05 | 2014-07-16 | Orion Diagnostica Oy | Method |
| CN106574305B (zh) | 2014-06-13 | 2021-03-02 | 生命技术公司 | 多重核酸扩增 |
| US10316369B2 (en) | 2014-06-27 | 2019-06-11 | Seminis Vegetable Seeds, Inc. | Methods and assays for male sterile watermelon |
| EP3169793B1 (de) | 2014-07-16 | 2022-07-06 | Tangen Biosciences Inc. | Isothermische verfahren zur amplifizierung von nukleinsäureproben |
| ES2729302T3 (es) | 2014-09-29 | 2019-10-31 | Illumina Cambridge Ltd | Mutantes de recombinasas |
| EP3005862A1 (de) | 2014-10-10 | 2016-04-13 | Seminis Vegetable Seeds, Inc. | Melonenpflanzen mit verbesserter krankheitstoleranz |
| US11559801B2 (en) | 2014-11-03 | 2023-01-24 | Tangen Biosciences, Inc. | Apparatus and method for cell, spore, or virus capture and disruption |
| BR112017023275B1 (pt) | 2015-04-28 | 2023-11-21 | Monsanto Technology Llc | Métodos para selecionar uma planta ou semente de milho braquítica |
| UA126326C2 (uk) | 2015-04-30 | 2022-09-21 | Монсанто Текнолоджі Елелсі | Спосіб відбору рослини каноли, стійкої до кили капустяних |
| EP3303611B1 (de) | 2015-05-29 | 2019-10-02 | Roche Diagnostics GmbH | Verfahren zur inaktivierung von mikroben durch citraconsäureanhydrid |
| EP3307908B1 (de) | 2015-06-09 | 2019-09-11 | Life Technologies Corporation | Verfahren zur molekularen markierung |
| WO2017031059A1 (en) | 2015-08-18 | 2017-02-23 | Monsanto Technology Llc | Methods for producing cotton plants with enhanced drought tolerance and compositions thereof |
| US10448595B2 (en) | 2015-09-03 | 2019-10-22 | Seminis Vegetable Seeds, Inc. | Downy mildew resistant lettuce plants |
| US10858709B2 (en) | 2015-09-10 | 2020-12-08 | Monsanto Technology Llc | Methods for producing corn plants with downy mildew resistance and compositions thereof |
| GB201519565D0 (en) | 2015-11-05 | 2015-12-23 | Alere San Diego Inc | Sample preparation device |
| US20180363037A1 (en) | 2015-12-09 | 2018-12-20 | Life Technologies Corporation | Detection and quantification of nucleic acid molecules associated with a surface |
| US10694693B2 (en) | 2015-12-18 | 2020-06-30 | Monsanto Technology Llc | Methods for producing corn plants with northern leaf blight resistance and compositions thereof |
| US10329601B2 (en) | 2015-12-28 | 2019-06-25 | Ionian Technologies, Inc. | Nicking and extension amplification reaction (NEAR) of Streptococcus species |
| US10626383B2 (en) | 2016-01-15 | 2020-04-21 | Thermo Fisher Scientific Baltics Uab | Thermophilic DNA polymerase mutants |
| WO2017147486A1 (en) | 2016-02-26 | 2017-08-31 | Alere San Diego Inc. | Redox labeled oligonucleotide probes and their use |
| EP3423599B1 (de) | 2016-03-04 | 2023-04-19 | Abbott Diagnostics Scarborough, Inc. | Geraet fuer automatisierte nested rekombinase-polymerase-amplifikation |
| JP6921829B2 (ja) | 2016-03-28 | 2021-08-18 | イラミーナ インコーポレーテッド | リコンビナーゼ変異体 |
| US11299777B2 (en) | 2016-04-04 | 2022-04-12 | Nat Diagnostics, Inc. | Isothermal amplification components and processes |
| US9617587B1 (en) | 2016-04-04 | 2017-04-11 | Nat Diagnostics, Inc. | Isothermal amplification components and processes |
| US11268117B2 (en) | 2016-06-10 | 2022-03-08 | Life Technologies Corporation | Methods and compositions for nucleic acid amplification |
| CN116397014A (zh) | 2016-07-20 | 2023-07-07 | 测序健康公司 | 用于核酸测序的系统和方法 |
| WO2018031874A1 (en) | 2016-08-11 | 2018-02-15 | Monsanto Technology Llc | Methods and compositions for producing corn plants with resistance to late wilt |
| CA3029274A1 (en) | 2016-09-15 | 2018-03-22 | Sophie Laurenson | Devices and methods for sample analysis |
| AU2017232187B2 (en) | 2016-09-30 | 2023-11-09 | Seminis Vegetable Seeds, Inc. | Xanthomonas resistant brassica oleracea plants |
| WO2018071522A1 (en) | 2016-10-11 | 2018-04-19 | Life Technologies Corporation | Rapid amplification of nucleic acids |
| CN106701738B (zh) * | 2016-11-10 | 2020-05-08 | 中国科学院成都生物研究所 | 一种等温解开双链dna及制备单链dna的方法 |
| BR112019017947A2 (pt) | 2017-02-28 | 2020-05-19 | Alere San Diego Inc | dispositivo microfluídico, leitor configurado para recebê-lo e método |
| US11542540B2 (en) | 2017-06-16 | 2023-01-03 | Life Technologies Corporation | Control nucleic acids, and compositions, kits, and uses thereof |
| EP3645710A1 (de) | 2017-06-26 | 2020-05-06 | Thermo Fisher Scientific Baltics Uab | Thermophile dna-polymerase-mutanten |
| BR112020004071A2 (pt) | 2017-08-31 | 2020-09-24 | Ionian Technologies, Inc. | reação de amplificação por nicking e extensão (near) de espécies do vírus sincicial respiratório |
| MX2020003113A (es) | 2017-09-21 | 2020-09-07 | Genapsys Inc | Sistemas y metodos para secuenciar acido nucleico. |
| CN111566223B (zh) | 2017-11-07 | 2024-04-12 | 生命技术公司 | 用于操纵核酸的方法和组合物 |
| CN108034763B (zh) * | 2017-12-21 | 2021-10-22 | 北京卓诚惠生生物科技股份有限公司 | 检测甲型肝炎和戊型肝炎病毒的引物、探针及试剂盒 |
| US10597714B2 (en) | 2017-12-29 | 2020-03-24 | Clear Labs, Inc. | Automated priming and library loading device |
| SG11201903333SA (en) | 2017-12-29 | 2019-08-27 | Clear Labs Inc | Automated priming and library loading services |
| US10246704B1 (en) | 2017-12-29 | 2019-04-02 | Clear Labs, Inc. | Detection of microorganisms in food samples and food processing facilities |
| US11268102B2 (en) | 2018-05-16 | 2022-03-08 | University Of Florida Research Foundation, Incorporated | Compositions and methods for identifying and selecting brachytic locus in solanaceae |
| WO2019238765A1 (en) | 2018-06-12 | 2019-12-19 | Keygene N.V. | Nucleic acid amplification method |
| CN108410954A (zh) * | 2018-07-10 | 2018-08-17 | 默禾医疗科技（上海）有限公司 | 一种室温扩增反应体系中反应缓冲液的制配方法 |
| KR20210103931A (ko) | 2018-12-14 | 2021-08-24 | 일루미나 케임브리지 리미티드 | 서열분석 동안 비표지된 뉴클레오타이드에 의한 페이싱 감소 |
| WO2020126593A1 (en) | 2018-12-17 | 2020-06-25 | Illumina Cambridge Limited | Compositions for use in polyunucleotide sequencing |
| SG11202012758WA (en) | 2018-12-17 | 2021-01-28 | Illumina Cambridge Ltd | Primer oligonucleotide for sequencing |
| CA3126761C (en) | 2019-01-15 | 2023-01-10 | Seminis Vegetable Seeds, Inc. | Green bean plants with improved disease resistance |
| EP3963103B1 (de) | 2019-05-03 | 2024-02-28 | Life Technologies Corporation | Verfahren und zusammensetzungen zur manipulation von nukleinsäuren |
| WO2021011850A2 (en) * | 2019-07-17 | 2021-01-21 | Chao Chien Chung | Amplification assay for the detection of anaplasma phagocytophilum |
| KR20220062302A (ko) | 2019-08-21 | 2022-05-16 | 라이프 테크놀로지스 코포레이션 | 시퀀싱을 위한 시스템 및 방법 |
| SG10202008262UA (en) | 2019-09-26 | 2021-04-29 | Seminis Vegetable Seeds Inc | Lettuce plants having resistance to nasonovia ribisnigri biotype nr:1 |
| GB201916379D0 (en) | 2019-11-11 | 2019-12-25 | Biocrucible Ltd | Biochemical reaction methods and reagents |
| WO2021226754A1 (zh) * | 2020-05-09 | 2021-11-18 | 杭州梓晶生物有限公司 | 一种病毒重组酶-聚合酶扩增检测方法 |
| WO2021228839A1 (en) | 2020-05-11 | 2021-11-18 | Deutsches Krebsforschungszentrum | Polynucleotide detection by cas nucleases |
| AU2021204717A1 (en) | 2020-07-15 | 2022-02-03 | Seminis Vegetable Seeds, Inc. | Green Bean Plants with Improved Disease Resistance |
| US20220170093A1 (en) | 2020-11-16 | 2022-06-02 | Life Technologies Corporation | System and method for sequencing |
| CA3211098A1 (en) | 2021-03-09 | 2022-09-15 | Chantal Fournier-Wirth | Detection of infectious agent based on recombinase polymerase amplification combined with a magnetic field-enhanced agglutination |
| AU2022264434A1 (en) | 2021-04-29 | 2023-11-02 | Abbott Laboratories | Systems and methods for pooling samples for high-throughput analysis |
| CN113891944A (zh) * | 2021-06-24 | 2022-01-04 | 黄婉秋 | 检测病原体rna、及动物或人类基因rna的试剂盒及其应用 |
| GB202110485D0 (en) | 2021-07-21 | 2021-09-01 | Dnae Diagnostics Ltd | Compositions, kits and methods for sequencing target polynucleotides |
| WO2023002203A1 (en) | 2021-07-21 | 2023-01-26 | Dnae Diagnostics Limited | Method and system comprising a cartridge for sequencing target polynucleotides |
| GB202110479D0 (en) | 2021-07-21 | 2021-09-01 | Dnae Diagnostics Ltd | Compositions, kits and methods for sequencing target polynucleotides |
| WO2023014222A1 (en) | 2021-08-03 | 2023-02-09 | Wageningen Universiteit | Argonaute-based nucleic acid detection system |
| US20230096386A1 (en) | 2021-09-30 | 2023-03-30 | Illumina Cambridge Limited | Polynucleotide sequencing |
| CN114237548B (zh) * | 2021-11-22 | 2023-07-18 | 南京大学 | 基于非易失性存储器阵列的复数点乘运算的方法及系统 |
| US20230193310A1 (en) | 2021-12-10 | 2023-06-22 | Seminis Vegetabe Seeds, Inc. | Lettuce plants having resistance to downy mildew |
| WO2023250288A2 (en) | 2022-06-21 | 2023-12-28 | Seminis Vegetable Seeds, Inc. | Novel qtls conferring resistance to cucumber mosaic virus |
| WO2024030985A1 (en) | 2022-08-04 | 2024-02-08 | Abbott Laboratories | Assays for detecting monkeypox virus |
| US20240109063A1 (en) | 2022-09-29 | 2024-04-04 | Illumina, Inc. | Dynamic optical system calibration |
Family Cites Families (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US603585A (en) | 1898-05-03 | cbowell | ||
| US5430136A (en) | 1984-10-16 | 1995-07-04 | Chiron Corporation | Oligonucleotides having selectably cleavable and/or abasic sites |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US5635347A (en) * | 1986-04-30 | 1997-06-03 | Igen, Inc. | Rapid assays for amplification products |
| US5858652A (en) * | 1988-08-30 | 1999-01-12 | Abbott Laboratories | Detection and amplification of target nucleic acid sequences |
| GB8903627D0 (en) | 1989-02-17 | 1989-04-05 | Unilever Plc | Assays |
| KR950013953B1 (ko) * | 1990-01-26 | 1995-11-18 | 애보트 래보라토리즈 | 리가제 연쇄 반응에 적용가능한 표적 핵산의 증폭 방법 |
| US5326692B1 (en) | 1992-05-13 | 1996-04-30 | Molecular Probes Inc | Fluorescent microparticles with controllable enhanced stokes shift |
| CA2116215C (en) * | 1990-05-07 | 1998-12-22 | Tapestry Pharmaceuticals, Inc. | Diagnostic applications of double d-loop formation |
| US5223414A (en) * | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
| US5273881A (en) * | 1990-05-07 | 1993-12-28 | Daikin Industries, Ltd. | Diagnostic applications of double D-loop formation |
| ATE176002T1 (de) | 1990-07-24 | 1999-02-15 | Hoffmann La Roche | Verringerung von nicht spezifischer amplifikation während einer (in vitro) nukleinsäure amplifikation unter verwendung von modifizierten nukleinsäure basen |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| US5556751A (en) | 1991-04-25 | 1996-09-17 | Amoco Corporation | Selective amplification system using Q-β replicase |
| EP0524349A1 (de) * | 1991-07-08 | 1993-01-27 | Opticon Sensors Europe B.V. | Abtaster mit zwei Brennweiten und die Verwendung eines solchen Abtasters als Lesestift für Kodierungen |
| CA2077135A1 (en) * | 1991-08-30 | 1993-03-01 | Joh-E Ikeda | A method of dna amplification |
| WO1994003624A1 (en) | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
| US5733733A (en) | 1992-08-04 | 1998-03-31 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
| US5614389A (en) | 1992-08-04 | 1997-03-25 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
| US5834202A (en) | 1992-08-04 | 1998-11-10 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
| CA2122203C (en) | 1993-05-11 | 2001-12-18 | Melinda S. Fraiser | Decontamination of nucleic acid amplification reactions |
| FR2708288B1 (fr) * | 1993-07-26 | 1995-09-01 | Bio Merieux | Procédé d'amplification d'acides nucléiques par transcription utilisant le déplacement, réactifs et nécessaire pour la mise en Óoeuvre de ce procédé. |
| US6165793A (en) | 1996-03-25 | 2000-12-26 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| US5942391A (en) | 1994-06-22 | 1999-08-24 | Mount Sinai School Of Medicine | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
| US5705366A (en) | 1994-09-15 | 1998-01-06 | Johnson & Johnson Clinical Diagnostics, Inc. | Coamplification of target nucleic acids using volume exclusion agent in reaction composition, test kit and test device useful therefor |
| US5656430A (en) | 1995-06-07 | 1997-08-12 | Trevigen, Inc. | Oscillating signal amplifier for nucleic acid detection |
| US5916779A (en) | 1995-09-21 | 1999-06-29 | Becton, Dickinson And Company | Strand displacement amplification of RNA targets |
| US5731150A (en) | 1995-11-01 | 1998-03-24 | Chiron Diagnostic Corporation | IS6110 based molecular detection of mycobacterium tuberculosis |
| CA2257197A1 (en) * | 1996-06-03 | 1997-12-11 | Jeffrey Edberg | Fc receptor polymorphism |
| US5853990A (en) * | 1996-07-26 | 1998-12-29 | Edward E. Winger | Real time homogeneous nucleotide assay |
| AU712873B2 (en) * | 1996-08-29 | 1999-11-18 | Tapestry Pharmaceuticals, Inc. | Methods for targeting, enriching, detecting and/or isolating target nucleic acidsequence using reca-like recombinase |
| CA2256563A1 (en) | 1997-04-04 | 1998-10-15 | Innogenetics N.V. | Isothermal polymerase chain reaction by cycling the concentration of divalent metal ions |
| US6245506B1 (en) | 1997-07-30 | 2001-06-12 | Bbi Bioseq, Inc. | Integrated sequencing device |
| DE69804143T2 (de) | 1998-04-22 | 2002-08-01 | Entpr Ie Trd As Bioresearch Ie | Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasst |
| WO1999060158A1 (fr) | 1998-05-19 | 1999-11-25 | Laboratory Of Molecular Biophotonics | Phase solide utilisee pour detecter de l'acide nucleique et procede de detection d'acide nucleique |
| US6140054A (en) * | 1998-09-30 | 2000-10-31 | University Of Utah Research Foundation | Multiplex genotyping using fluorescent hybridization probes |
| US6087112A (en) * | 1998-12-30 | 2000-07-11 | Oligos Etc. Inc. | Arrays with modified oligonucleotide and polynucleotide compositions |
| WO2000041524A2 (en) | 1999-01-11 | 2000-07-20 | President And Fellows Of Harvard College | Isothermal amplification of dna |
| WO2000046408A1 (en) | 1999-02-04 | 2000-08-10 | Sloan-Kettering Institute For Cancer Research | Process for dna replication |
| US6699693B1 (en) * | 1999-02-04 | 2004-03-02 | Sloan-Kettering Institute For Cancer Research | Process for DNA replication |
| US6387621B1 (en) | 1999-04-27 | 2002-05-14 | University Of Utah Research Foundation | Automated analysis of real-time nucleic acid amplification |
| US6509157B1 (en) * | 1999-11-05 | 2003-01-21 | Roche Molecular Systems, Inc | 3 blocked nucleic acid amplification primers |
| NO314091B1 (no) * | 2000-01-12 | 2003-01-27 | Biotec Pharmacon Asa | Varmelabil uracil-DNA-glykosylase, DNA-sekvens som koder for enzymet, mikroorganisme som inneholder DNA-sekvensen, samt anvendelse av enzymet |
| WO2001070947A2 (en) | 2000-03-20 | 2001-09-27 | Maxygen, Inc. | Method for generating recombinant dna molecules in complex mixtures |
| ATE334228T1 (de) | 2000-03-29 | 2006-08-15 | Lgc Ltd | Hybridisierungsprobe und methode zum schnellen nachweis und zur schnellen unterscheidung von sequenzen |
| US20020061530A1 (en) | 2000-07-31 | 2002-05-23 | Belotserkovskii Boris P. | Enhanced targeting of DNA sequences by recombinase protein and single-stranded homologous DNA probes using DNA analog activation |
| IE20000887A1 (en) | 2000-11-03 | 2002-12-11 | Univ College Cork Nat Univ Ie | Method for the amplification and optional characterisation of nucleic acids |
| US6379899B1 (en) * | 2001-03-13 | 2002-04-30 | Discoverx | Isothermal exponential RNA amplification in complex mixtures |
| EP1386006B1 (de) | 2001-04-20 | 2008-05-28 | The Penn State Research Foundation | Verfahren zur manipulation von nukleinsäuren |
| EP1275735A1 (de) | 2001-07-11 | 2003-01-15 | Roche Diagnostics GmbH | Zusammensetzung und Methode zur 'Hot start' Nukleinsäureamplifizierung |
| WO2003008622A2 (en) | 2001-07-15 | 2003-01-30 | Keck Graduate Institute | Exponential nucleic acid amplification using nicking endonucleases |
| WO2003008624A2 (en) | 2001-07-15 | 2003-01-30 | Keck Graduate Institute | Nucleic acid amplification using nicking agents |
| WO2003016569A1 (fr) | 2001-08-20 | 2003-02-27 | Takara Bio Inc. | Methodes d'amplification d'acide nucleique |
| EP1446502A4 (de) | 2001-09-28 | 2005-02-09 | Univ Delaware | Nachweis und trennung von polymorphismen |
| KR100445560B1 (ko) | 2001-10-31 | 2004-08-21 | (주)바이오넥스 | 핵산 또는 생물학적 물질을 분리하기 위한 키트의 제조방법과, 그 방법에 의해 제조된 키트와, 그 키트를사용하는 장치 |
| US7244562B2 (en) * | 2001-11-01 | 2007-07-17 | Gene Check, Inc. | RecA assisted detection of mutations, single nucleotide polymorphisms and specific sequences |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| ATE400663T1 (de) | 2002-02-21 | 2008-07-15 | Asm Scient Inc | Rekombinase-polymerase-amplifikation |
| US8030000B2 (en) | 2002-02-21 | 2011-10-04 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US20040137456A1 (en) * | 2002-04-04 | 2004-07-15 | Hiroki Yokota | Method for identifying and characterizing individual dna molecules |
| US20030228611A1 (en) | 2002-05-01 | 2003-12-11 | President And Fellows Of Harvard College | Nucleic acid memory device |
| US6713262B2 (en) | 2002-06-25 | 2004-03-30 | Agilent Technologies, Inc. | Methods and compositions for high throughput identification of protein/nucleic acid binding pairs |
| AU2003260679A1 (en) | 2002-07-12 | 2004-02-02 | British Biocell International Limited | Lateral flow assay device and method |
| US20040038213A1 (en) | 2002-08-06 | 2004-02-26 | Kwon Jai W. | Genotyping by in situ PCR amplification of a polynucleotide in a tissue biopsy |
| US7252940B2 (en) | 2002-08-21 | 2007-08-07 | Epoch Biosciences, Inc. | Abasic site endonuclease assay |
| US7662594B2 (en) | 2002-09-20 | 2010-02-16 | New England Biolabs, Inc. | Helicase-dependent amplification of RNA |
| US7282328B2 (en) * | 2002-09-20 | 2007-10-16 | New England Biolabs, Inc. | Helicase dependent amplification of nucleic acids |
| CA2518452A1 (en) * | 2003-03-11 | 2004-09-23 | Gene Check, Inc. | Reca-assisted allele specific oligonucleotide extension method for detecting mutations, snps and specific sequences |
| DE10315640A1 (de) | 2003-04-04 | 2004-10-14 | Ignatov, Konstantin | Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung |
| JP2005110621A (ja) * | 2003-10-10 | 2005-04-28 | Aisin Seiki Co Ltd | 核酸増幅方法及び核酸増幅用試薬キット |
| EP1564306B1 (de) | 2004-02-17 | 2013-08-07 | Affymetrix, Inc. | Verfahren zur Fragmentierung und Markierung von DNS |
| ES2718482T3 (es) * | 2004-06-01 | 2019-07-02 | Alere San Diego Inc | Kit para amplificación de recombinasa polimerasa |
| US7745125B2 (en) | 2004-06-28 | 2010-06-29 | Roche Molecular Systems, Inc. | 2′-terminator related pyrophosphorolysis activated polymerization |
| ATE396282T1 (de) | 2004-10-11 | 2008-06-15 | Epigenomics Ag | Verfahren zum kontaminationsschutz von dna- amplifikationsreaktionen zur methylierungsanalyse durch modifizierte vorbehandlung der nukleinsäuren |
| US20060110765A1 (en) | 2004-11-23 | 2006-05-25 | Wang Xiao B | Detection of nucleic acid variation by cleavage-amplification (CleavAmp) method |
| WO2006119280A2 (en) | 2005-05-03 | 2006-11-09 | Handylab, Inc. | Lyophilized pellets |
| US20070042427A1 (en) | 2005-05-03 | 2007-02-22 | Micronics, Inc. | Microfluidic laminar flow detection strip |
| AU2006251866B2 (en) | 2005-05-26 | 2007-11-29 | Human Genetic Signatures Pty Ltd | Isothermal strand displacement amplification using primers containing a non-regular base |
| WO2007008997A2 (en) | 2005-07-12 | 2007-01-18 | The Board Of Trustees Of The Leland Stanford Junior University | Template specific inhibition of pcr |
| EP2385140B1 (de) | 2005-07-25 | 2014-07-16 | Alere San Diego, Inc. | Verfahren zur Multiplexierung einer Rekombinase-Polymerase-Verstärkung |
| JP2009535053A (ja) * | 2006-05-04 | 2009-10-01 | エーエスエム サイエンティフィック， インコーポレイテッド | レコンビナーゼポリメラーゼ増幅 |
| EP2155912B1 (de) | 2007-05-18 | 2013-06-26 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services | Primer und sonden zur detektion von streptococcus pneumoniae |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| ES2320840B1 (es) | 2007-11-27 | 2010-07-01 | Nelson Alfonso Egued | Tubo humectador de doble camara. |
| JP2009139487A (ja) | 2007-12-04 | 2009-06-25 | Nippon Sheet Glass Co Ltd | 正立等倍レンズアレイプレート |
| WO2010135310A1 (en) | 2009-05-20 | 2010-11-25 | Biosite Incorporated | Dna glycosylase/lyase and ap endonuclease substrates |
| EP3360974A1 (de) | 2009-06-05 | 2018-08-15 | Alere San Diego, Inc. | Reagentien zur rekombinase polymerase amplifikation |
| EP2859111B1 (de) | 2012-06-08 | 2020-07-08 | Ionian Technologies, LLC | Nukleinsäureamplifizierungen |
-
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- 2003-02-21 AT AT03711216T patent/ATE400663T1/de active
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