DE60329618D1 - Ip3-protein-bindungstest - Google Patents
Ip3-protein-bindungstestInfo
- Publication number
- DE60329618D1 DE60329618D1 DE60329618T DE60329618T DE60329618D1 DE 60329618 D1 DE60329618 D1 DE 60329618D1 DE 60329618 T DE60329618 T DE 60329618T DE 60329618 T DE60329618 T DE 60329618T DE 60329618 D1 DE60329618 D1 DE 60329618D1
- Authority
- DE
- Germany
- Prior art keywords
- protein binding
- binding test
- conjugate
- reagents
- detectable label
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42046902P | 2002-10-21 | 2002-10-21 | |
| PCT/US2003/033262 WO2004038369A2 (en) | 2002-10-21 | 2003-10-20 | Ip3 protein binding assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60329618D1 true DE60329618D1 (de) | 2009-11-19 |
Family
ID=32176572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60329618T Expired - Fee Related DE60329618D1 (de) | 2002-10-21 | 2003-10-20 | Ip3-protein-bindungstest |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040106158A1 (de) |
| EP (1) | EP1556682B8 (de) |
| JP (1) | JP2006503582A (de) |
| AT (1) | ATE445165T1 (de) |
| AU (1) | AU2003301583A1 (de) |
| CA (1) | CA2503228A1 (de) |
| DE (1) | DE60329618D1 (de) |
| WO (1) | WO2004038369A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005029039A2 (en) * | 2003-09-19 | 2005-03-31 | Echelon Biosciences Incorporated | Non-radioactive inositol phosphate assay for phospholipase c-coupled drug target screening |
| FR2878850B1 (fr) | 2004-12-02 | 2008-10-31 | Cis Bio Internat Sa | Derives de l'inositol-1-phosphate |
| US7741506B2 (en) * | 2005-04-26 | 2010-06-22 | Berry & Associates, Inc. | Probe for measuring phytase activity |
| US20060241308A1 (en) * | 2005-04-26 | 2006-10-26 | Berry & Associates, Inc. | Probe for measuring phytase activity |
| GB0920985D0 (en) * | 2009-11-30 | 2010-01-13 | Queen Mary & Westfield College | Novel inositol phosphate derivatives |
| CN102410995B (zh) * | 2011-08-23 | 2013-07-31 | 四川汇宇制药有限公司 | 基于荧光偏振分析的ip3受体靶标药物的筛选方法 |
| CN102286094A (zh) * | 2011-08-23 | 2011-12-21 | 四川汇宇制药有限公司 | 截短的ip3受体v33k-nt及其应用 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3852157A (en) * | 1971-05-14 | 1974-12-03 | Syva Corp | Compounds for enzyme amplification assay |
| US4067774A (en) * | 1971-05-14 | 1978-01-10 | Syva Company | Compounds for enzyme amplification assay |
| US3905871A (en) * | 1971-05-14 | 1975-09-16 | Syva Co | Lactam conjugates to enzymes |
| US4191613A (en) * | 1971-05-14 | 1980-03-04 | Syva Company | Malate dehydrogenase conjugates for enzyme immunoassays |
| US4046636A (en) * | 1974-06-20 | 1977-09-06 | Syva Company | Diazepam enzyme conjugates |
| US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US4039385A (en) * | 1972-05-08 | 1977-08-02 | Syva Company | Cardiac glycoside enzyme conjugates |
| US3966556A (en) * | 1972-11-06 | 1976-06-29 | Syva Company | Compounds for enzyme amplification assay methadone analogs |
| US3875011A (en) * | 1972-11-06 | 1975-04-01 | Syva Co | Enzyme immunoassays with glucose-6-phosphate dehydrogenase |
| US4161515A (en) * | 1973-10-02 | 1979-07-17 | Syva Company | Double receptor fluorescent immunoassay |
| US3998943A (en) * | 1973-10-02 | 1976-12-21 | Syva Company | Double receptor fluorescent immunoassay |
| US3935074A (en) * | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US4040907A (en) * | 1974-06-20 | 1977-08-09 | Syva Company | Iodothyronine enzyme conjugates |
| US3996345A (en) * | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4065354A (en) * | 1974-10-10 | 1977-12-27 | Syva Company | Lysozyme conjugates for enzyme immunoassays |
| US4171244A (en) * | 1975-02-20 | 1979-10-16 | Syva Company | Enzyme-bound-polyidothyronine |
| US4043872A (en) * | 1975-02-20 | 1977-08-23 | Syva Company | Polyiodothyronine immunoassay |
| US4174384A (en) * | 1975-06-30 | 1979-11-13 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4134792A (en) * | 1976-12-06 | 1979-01-16 | Miles Laboratories, Inc. | Specific binding assay with an enzyme modulator as a labeling substance |
| US4130462A (en) * | 1976-12-16 | 1978-12-19 | Syva Company | Receptor steric hindrance immunoassay for receptor determination |
| IT1079045B (it) * | 1977-05-16 | 1985-05-08 | Syva Co | Analisi imuunologica fluorescente a doppio ricettore |
| US4160645A (en) * | 1977-07-14 | 1979-07-10 | Syva Company | Catalyst mediated competitive protein binding assay |
| US4208479A (en) * | 1977-07-14 | 1980-06-17 | Syva Company | Label modified immunoassays |
| US4318980A (en) * | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| US4193983A (en) * | 1978-05-16 | 1980-03-18 | Syva Company | Labeled liposome particle compositions and immunoassays therewith |
| US4213893A (en) * | 1978-10-12 | 1980-07-22 | Miles Laboratories, Inc. | Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays |
| US4318983A (en) * | 1979-06-04 | 1982-03-09 | Miles Laboratories, Inc. | Fad-labeled specific binding assay monitored with apoglutathione reductase or apolipoamide dehydrogenase |
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| US4378428A (en) * | 1981-03-30 | 1983-03-29 | Baker Instruments Corporation | Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays |
| US4708929A (en) * | 1984-10-29 | 1987-11-24 | Microgenics Corporation | Methods for protein binding enzyme complementation assays |
| US4956274A (en) * | 1987-04-06 | 1990-09-11 | Microgenics Corporation | Reagent stabilization in enzyme-donor and acceptor assay |
| SE8902241L (sv) * | 1989-06-21 | 1990-12-22 | Perstorp Ab | Saett att analytiskt separera inositolfosfater med en kvartaer amin |
| US5252707A (en) * | 1989-09-22 | 1993-10-12 | Mitsui Toatsu Chemicals Incorporated | Inositol derivative and method for preparing same |
| JP2778771B2 (ja) * | 1989-12-14 | 1998-07-23 | 協和醗酵工業株式会社 | 新規ポリペプチド |
| US5393912A (en) * | 1994-01-13 | 1995-02-28 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | D-myo-inositol 1,4,5-trisphosphate analogues |
| US5977311A (en) * | 1997-09-23 | 1999-11-02 | Curagen Corporation | 53BP2 complexes |
| US6465211B1 (en) * | 1998-08-27 | 2002-10-15 | Riken | Nucleic acids, vectors and transformed cells for making and using high affinity IP-3 binding polypeptides |
| AU5870800A (en) * | 1999-06-09 | 2000-12-28 | Ljl Biosystems, Inc. | Cell-signaling assays |
| DE60225271T2 (de) * | 2001-05-09 | 2009-03-05 | Discoverx, Inc., Fremont | Screening auf enzyminhibitoren |
| US20040137480A1 (en) * | 2001-08-30 | 2004-07-15 | Eglen Richard M. | Monitoring intracellular proteins |
| WO2003021265A1 (en) * | 2001-08-30 | 2003-03-13 | Discoverx, Inc. | Genetic construct intracellular monitoring system |
| US20060105377A1 (en) * | 2001-08-30 | 2006-05-18 | Eglen Richard M | Screening to optimize RNAi |
| AU2003231060A1 (en) * | 2002-05-02 | 2003-11-17 | Discoverx, Inc. | Short enzyme donor fragment |
| ATE455862T1 (de) * | 2002-05-29 | 2010-02-15 | Discoverx Corp | Verbesserter rezeptornachweis |
| WO2005047305A2 (en) * | 2003-11-06 | 2005-05-26 | Discoverx, Inc. | Cellular membrane protein assay |
| US7410755B2 (en) * | 2005-02-22 | 2008-08-12 | Discoverx | ADP detection using an enzyme-coupled reaction |
| WO2007002200A2 (en) * | 2005-06-21 | 2007-01-04 | Discoverx, Inc. | Mitotic index assay |
| US7537910B2 (en) * | 2005-06-23 | 2009-05-26 | Discoverx Corp. | Lactamase amplification substrate |
-
2003
- 2003-10-20 WO PCT/US2003/033262 patent/WO2004038369A2/en active Application Filing
- 2003-10-20 US US10/689,122 patent/US20040106158A1/en not_active Abandoned
- 2003-10-20 CA CA002503228A patent/CA2503228A1/en not_active Abandoned
- 2003-10-20 JP JP2004546937A patent/JP2006503582A/ja not_active Withdrawn
- 2003-10-20 DE DE60329618T patent/DE60329618D1/de not_active Expired - Fee Related
- 2003-10-20 AU AU2003301583A patent/AU2003301583A1/en not_active Abandoned
- 2003-10-20 EP EP03809590A patent/EP1556682B8/de not_active Expired - Lifetime
- 2003-10-20 AT AT03809590T patent/ATE445165T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003301583A1 (en) | 2004-05-13 |
| EP1556682B8 (de) | 2010-02-17 |
| ATE445165T1 (de) | 2009-10-15 |
| US20040106158A1 (en) | 2004-06-03 |
| AU2003301583A8 (en) | 2004-05-13 |
| WO2004038369A3 (en) | 2004-07-01 |
| WO2004038369A2 (en) | 2004-05-06 |
| CA2503228A1 (en) | 2004-05-06 |
| JP2006503582A (ja) | 2006-02-02 |
| EP1556682B1 (de) | 2009-10-07 |
| EP1556682A4 (de) | 2007-06-06 |
| EP1556682A2 (de) | 2005-07-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |