DE60330322D1 - Arzneimittel-mikroteilchen - Google Patents
Arzneimittel-mikroteilchenInfo
- Publication number
- DE60330322D1 DE60330322D1 DE60330322T DE60330322T DE60330322D1 DE 60330322 D1 DE60330322 D1 DE 60330322D1 DE 60330322 T DE60330322 T DE 60330322T DE 60330322 T DE60330322 T DE 60330322T DE 60330322 D1 DE60330322 D1 DE 60330322D1
- Authority
- DE
- Germany
- Prior art keywords
- microparticles
- medicines
- making
- methods
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
- B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36795702P | 2002-03-26 | 2002-03-26 | |
PCT/US2003/009327 WO2003082247A2 (en) | 2002-03-26 | 2003-03-25 | Drug microparticles |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60330322D1 true DE60330322D1 (de) | 2010-01-14 |
Family
ID=28675427
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60330322T Expired - Lifetime DE60330322D1 (de) | 2002-03-26 | 2003-03-25 | Arzneimittel-mikroteilchen |
Country Status (17)
Country | Link |
---|---|
US (6) | US20030224059A1 (de) |
EP (5) | EP2087882A1 (de) |
JP (1) | JP2005531521A (de) |
KR (1) | KR20040098023A (de) |
AT (1) | ATE450252T1 (de) |
AU (2) | AU2003226021B2 (de) |
CA (1) | CA2480377A1 (de) |
DE (1) | DE60330322D1 (de) |
DK (1) | DK1487416T3 (de) |
EA (1) | EA200401252A1 (de) |
ES (1) | ES2334991T3 (de) |
HK (1) | HK1069126A1 (de) |
IL (1) | IL164152A0 (de) |
MX (1) | MXPA04009385A (de) |
NZ (1) | NZ535854A (de) |
PT (1) | PT1487416E (de) |
WO (1) | WO2003082247A2 (de) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2087882A1 (de) | 2002-03-26 | 2009-08-12 | Teva Pharmaceutical Industries Ltd. | Arzneimittelmikropartikel |
AU2003263480A1 (en) * | 2002-09-24 | 2004-04-19 | Ranbaxy Laboratories Limited | Oral pharmaceutical compositions of fenofibrate having high bioavailability |
WO2004073686A2 (en) * | 2003-02-20 | 2004-09-02 | Teva Pharmaceutical Industries Ltd. | Menthol solutions of drugs |
EP3087991A1 (de) | 2003-11-08 | 2016-11-02 | Prothera Biologics | Zusammensetzung von inter-alpha-hemmer-proteinen aus plasma zur therapeutische verwendung |
US20080249076A1 (en) * | 2003-12-03 | 2008-10-09 | Lifecycle Pharma A/S | Pharmaceutical Compositions Comprising Danazol |
US20050202079A1 (en) * | 2004-03-15 | 2005-09-15 | Mylan Pharmaceuticals Inc. | Novel orally administrable formulation of nitrofurantoin and a method for preparing said formulation |
US8216610B2 (en) * | 2004-05-28 | 2012-07-10 | Imaginot Pty Ltd. | Oral paracetamol formulations |
WO2006020984A2 (en) * | 2004-08-13 | 2006-02-23 | Teva Pharmaceutical Industries Ltd. | Cyclosporin formulations |
AU2005330266A1 (en) * | 2005-03-30 | 2006-10-12 | Teva Pharmaceutical Industries Ltd. | Improved formulations of fenofibrate containing menthol or PEG/poloxamer |
US20070148233A1 (en) * | 2005-12-28 | 2007-06-28 | Lerner E I | Pharmaceutical formulations of fenofibrate having improved bioavailability |
EP1707197A1 (de) | 2005-03-30 | 2006-10-04 | Teva Pharmaceutical Industries Ltd. | Zusammensetzungen, welche Fenofibrat und eine Tensidmischung beinhaltet |
CA2600407A1 (en) * | 2005-03-30 | 2006-10-12 | Teva Pharmaceutical Industries Ltd. | Fibrate compositions containing a surfactant mixture of peg-600 and poloxamer 407 |
US20070015833A1 (en) * | 2005-07-18 | 2007-01-18 | Moshe Flashner-Barak | Formulations of fenofibrate containing menthol |
US20070015834A1 (en) * | 2005-07-18 | 2007-01-18 | Moshe Flashner-Barak | Formulations of fenofibrate containing PEG/Poloxamer |
EP1954298A4 (de) | 2005-11-28 | 2012-10-31 | Imaginot Pty Ltd | Abgabesystem für eine orale therapeutische verbindung |
ES2643140T3 (es) * | 2005-12-22 | 2017-11-21 | Oakwood Laboratories L.L.C. | Sistema de suministro de liberación lenta sublimable y procedimiento de realización del mismo |
DK1803441T3 (da) | 2005-12-28 | 2009-08-03 | Teva Pharma | Farmaceutiske fenofibrat-formuleringer, der har forbedret biotilgængelighed |
BRPI0520821A2 (pt) * | 2005-12-28 | 2009-06-30 | Teva Pharma | formulações farmacêuticas de fenofibrato com biodisponibilidade melhorada |
TW200817047A (en) * | 2006-04-03 | 2008-04-16 | Teva Pharma | Drug microparticles |
EP2134327A1 (de) * | 2007-03-13 | 2009-12-23 | Sandoz AG | Pharmazeutische zusammensetzungen schlecht löslicher arzneimittel |
KR100790954B1 (ko) * | 2007-09-13 | 2008-01-04 | 영남대학교 산학협력단 | 이트라코나졸 함유 젤라틴 초미세 미립구 |
CA2726281C (en) | 2008-05-28 | 2023-04-18 | Prothera Biologics, Llc | Preparation and composition of inter-alpha inhibitor proteins from blood |
MX2011006307A (es) * | 2008-12-15 | 2011-10-14 | Banner Pharmacaps Inc | Metodos para aumentar la liberacion y absorcion de agentes activos insolubles en agua. |
CA2750711C (en) * | 2009-01-26 | 2015-07-07 | Teva Pharmaceutical Industries Ltd. | Processes for coating a carrier with microparticles |
AU2010253578B2 (en) | 2009-05-27 | 2014-01-30 | Samyang Biopharmaceuticals Corporation | A poorly soluble drug containing microsphere with improved bioavailability and method of preparing the same |
CN103619886B (zh) | 2011-06-29 | 2016-09-14 | 柯惠Lp公司 | 氧化纤维素的溶解 |
HUE055562T2 (hu) | 2011-11-23 | 2021-11-29 | Therapeuticsmd Inc | Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
IN2014DN09416A (de) | 2012-04-25 | 2015-07-17 | Spi Pharma Inc | |
US9271937B2 (en) | 2012-05-31 | 2016-03-01 | Covidien Lp | Oxidized cellulose microspheres |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US9499636B2 (en) | 2012-06-28 | 2016-11-22 | Covidien Lp | Dissolution of oxidized cellulose and particle preparation by cross-linking with multivalent cations |
AU2013312215C1 (en) | 2012-09-09 | 2018-09-06 | Prothera Biologics, Inc. | Treatment of disease using inter-alpha inhibitor proteins |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10413566B2 (en) | 2013-03-15 | 2019-09-17 | Covidien Lp | Thixotropic oxidized cellulose solutions and medical applications thereof |
EP3145489A1 (de) | 2014-05-22 | 2017-03-29 | TherapeuticsMD, Inc. | Natürliche kombinierte hormonersatzformulierungen und therapien |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
FR3039990B1 (fr) | 2015-08-10 | 2018-07-06 | Rhodia Operations | Procede d'encapsulation |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
BR112018070199A2 (pt) | 2016-04-01 | 2019-01-29 | Therapeuticsmd Inc | composição farmacêutica de hormônio esteroide |
WO2017205835A1 (en) | 2016-05-26 | 2017-11-30 | Allergan, Inc. | Production of rounded salt particles |
CA3033546A1 (en) * | 2016-08-30 | 2018-03-08 | Allergan, Inc. | Method of manufacturing coated beads |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
CA3208345A1 (en) | 2021-01-15 | 2022-07-21 | Aquestive Therapeutics, Inc. | Prodrug compositions and methods of treatment |
WO2023015183A1 (en) * | 2021-08-02 | 2023-02-09 | Cornell University | Polymer nanoparticles via condensed droplet polymerization |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3089818A (en) | 1960-06-02 | 1963-05-14 | Baxter Laboratories Inc | Water dispersible antibiotics |
DE2246013A1 (de) * | 1972-09-20 | 1974-03-28 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von poroesen tabletten |
JPS5429566B2 (de) | 1974-09-13 | 1979-09-25 | ||
US4900775A (en) | 1988-02-29 | 1990-02-13 | Gaf Chemicals Corporation | Solubilization of complexes of water-insoluble organic compounds by aqueous solutions of polyvinylpyrrolidone |
US5342625A (en) * | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
GB8921710D0 (en) * | 1989-09-26 | 1989-11-08 | Mentholatum Co Ltd | Ibuprofen triturates and topical compositions containing same |
HUT75616A (en) * | 1992-03-17 | 1997-05-28 | Pfizer | Method for prooucing porous delivery devices |
KR100333115B1 (ko) * | 1992-11-17 | 2002-12-02 | 미츠비시 파마 코포레이션 | 항정신병약함유서방성마이크로스피어및이의제조방법 |
IT1264020B (it) * | 1993-01-28 | 1996-09-09 | Recordati Chem Pharm | Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi |
SI9300504A (en) * | 1993-09-28 | 1995-04-30 | Krka | Process for preparation solid dispersions and deposits of calcium antagonist dihidropyrimidine derivates and pharmaceutical compositions comprising the same |
US5430021A (en) * | 1994-03-18 | 1995-07-04 | Pharmavene, Inc. | Hydrophobic drug delivery systems |
IE75744B1 (en) * | 1995-04-03 | 1997-09-24 | Elan Corp Plc | Controlled release biodegradable micro- and nanospheres containing cyclosporin |
US5766629A (en) * | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
JP2000507544A (ja) * | 1996-03-25 | 2000-06-20 | イーライ・リリー・アンド・カンパニー | 痛みの治療方法 |
US6096339A (en) * | 1997-04-04 | 2000-08-01 | Alza Corporation | Dosage form, process of making and using same |
JP2001507702A (ja) * | 1996-12-31 | 2001-06-12 | インヘイル・セラピューティックス・システムズ・インコーポレテッド | 親水性賦形剤を有する疎水性薬剤の水性懸濁液を噴霧乾燥させる方法およびその方法によって作製された組成物 |
FR2758459B1 (fr) * | 1997-01-17 | 1999-05-07 | Pharma Pass | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
KR19990001564A (ko) | 1997-06-16 | 1999-01-15 | 유충식 | 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제 |
US6027747A (en) | 1997-11-11 | 2000-02-22 | Terracol; Didier | Process for the production of dry pharmaceutical forms and the thus obtained pharmaceutical compositions |
US20030059471A1 (en) * | 1997-12-15 | 2003-03-27 | Compton Bruce Jon | Oral delivery formulation |
US6337092B1 (en) * | 1998-03-30 | 2002-01-08 | Rtp Pharma Inc. | Composition and method of preparing microparticles of water-insoluble substances |
US20010038855A1 (en) * | 1998-06-05 | 2001-11-08 | Desjardin Michael A. | Dosage form for administering prescribed dose |
SE9803240D0 (sv) * | 1998-09-24 | 1998-09-24 | Diabact Ab | A pharmaceutical composition having a rapid action |
WO2001085344A1 (en) * | 2000-04-26 | 2001-11-15 | Elan Pharma International, Ltd. | Apparatus for sanitary wet milling |
US6264987B1 (en) * | 2000-05-19 | 2001-07-24 | Alkermes Controlled Therapeutics Inc. Ii | Method for preparing microparticles having a selected polymer molecular weight |
US20020001617A1 (en) * | 2000-05-26 | 2002-01-03 | Chang-Hyun Lee | Rapidly disintegrating tablet and process for the manufacture thereof |
US6531158B1 (en) * | 2000-08-09 | 2003-03-11 | Impax Laboratories, Inc. | Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
DE60131862D1 (de) | 2000-09-20 | 2008-01-24 | Nycomed Pharma As | Herstellung von vitaminemulsionen und konzentrate davon |
US7276249B2 (en) * | 2002-05-24 | 2007-10-02 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
CA2461349C (en) | 2001-09-26 | 2011-11-29 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
US6878693B2 (en) * | 2001-09-28 | 2005-04-12 | Solubest Ltd. | Hydrophilic complexes of lipophilic materials and an apparatus and method for their production |
US20030185882A1 (en) * | 2001-11-06 | 2003-10-02 | Vergez Juan A. | Pharmaceutical compositions containing oxybutynin |
EP2087882A1 (de) | 2002-03-26 | 2009-08-12 | Teva Pharmaceutical Industries Ltd. | Arzneimittelmikropartikel |
US20020193386A1 (en) * | 2002-03-28 | 2002-12-19 | Inigo Pfeiffer | Polymorphic form of 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-alpha]pyrimidin-4-one and formulations thereof |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
AU2003205499A1 (en) | 2003-02-28 | 2004-09-17 | Anbics Patents-Licences Ag | Method for treatment and prevention of acute and chronic pseudomonas aeruginosa airway infections with inhalable macrolides |
US20040185108A1 (en) * | 2003-03-18 | 2004-09-23 | Short Robert E. | Method of preparing gas-filled polymer matrix microparticles useful for delivering drug |
KR20060085682A (ko) | 2003-10-10 | 2006-07-27 | 라이프사이클 파마 에이/에스 | 피브레이트 및 스타틴을 함유하는 고형 제제 |
AU2004294728A1 (en) | 2003-11-21 | 2005-06-16 | Galderma Research & Development, S.N.C. | Sprayable composition for the administration of vitamin D derivatives |
-
2003
- 2003-03-25 EP EP09004704A patent/EP2087882A1/de not_active Withdrawn
- 2003-03-25 ES ES03745623T patent/ES2334991T3/es not_active Expired - Lifetime
- 2003-03-25 JP JP2003579785A patent/JP2005531521A/ja active Pending
- 2003-03-25 EP EP09004875A patent/EP2085074A1/de not_active Withdrawn
- 2003-03-25 PT PT03745623T patent/PT1487416E/pt unknown
- 2003-03-25 AT AT03745623T patent/ATE450252T1/de not_active IP Right Cessation
- 2003-03-25 IL IL16415203A patent/IL164152A0/xx unknown
- 2003-03-25 CA CA002480377A patent/CA2480377A1/en not_active Abandoned
- 2003-03-25 AU AU2003226021A patent/AU2003226021B2/en not_active Ceased
- 2003-03-25 EP EP09004873A patent/EP2085072A1/de not_active Withdrawn
- 2003-03-25 NZ NZ535854A patent/NZ535854A/en unknown
- 2003-03-25 KR KR10-2004-7015217A patent/KR20040098023A/ko not_active Application Discontinuation
- 2003-03-25 EA EA200401252A patent/EA200401252A1/ru unknown
- 2003-03-25 EP EP03745623A patent/EP1487416B1/de not_active Expired - Lifetime
- 2003-03-25 MX MXPA04009385A patent/MXPA04009385A/es unknown
- 2003-03-25 US US10/400,100 patent/US20030224059A1/en not_active Abandoned
- 2003-03-25 DE DE60330322T patent/DE60330322D1/de not_active Expired - Lifetime
- 2003-03-25 DK DK03745623.3T patent/DK1487416T3/da active
- 2003-03-25 EP EP09004874A patent/EP2085073A1/de not_active Withdrawn
- 2003-03-25 WO PCT/US2003/009327 patent/WO2003082247A2/en active Application Filing
-
2005
- 2005-03-31 HK HK05102709.3A patent/HK1069126A1/xx not_active IP Right Cessation
-
2006
- 2006-02-17 US US11/356,682 patent/US20060141050A1/en not_active Abandoned
- 2006-02-17 US US11/357,248 patent/US20060141051A1/en not_active Abandoned
- 2006-02-17 US US11/357,757 patent/US20060141052A1/en not_active Abandoned
-
2008
- 2008-10-17 AU AU2008230007A patent/AU2008230007A1/en not_active Abandoned
-
2009
- 2009-12-10 US US12/635,417 patent/US8663703B2/en not_active Expired - Lifetime
-
2014
- 2014-01-16 US US14/156,714 patent/US9107832B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IL164152A0 (en) | 2005-12-18 |
US9107832B2 (en) | 2015-08-18 |
WO2003082247A3 (en) | 2004-02-05 |
US20140134256A1 (en) | 2014-05-15 |
CA2480377A1 (en) | 2003-10-09 |
ES2334991T3 (es) | 2010-03-18 |
AU2008230007A1 (en) | 2008-11-13 |
JP2005531521A (ja) | 2005-10-20 |
EA200401252A1 (ru) | 2005-04-28 |
EP1487416B1 (de) | 2009-12-02 |
US20060141052A1 (en) | 2006-06-29 |
EP2085074A1 (de) | 2009-08-05 |
AU2003226021B2 (en) | 2008-07-17 |
US8663703B2 (en) | 2014-03-04 |
AU2003226021A1 (en) | 2003-10-13 |
US20030224059A1 (en) | 2003-12-04 |
PT1487416E (pt) | 2010-01-25 |
WO2003082247A2 (en) | 2003-10-09 |
EP2087882A1 (de) | 2009-08-12 |
US20060141050A1 (en) | 2006-06-29 |
EP1487416A2 (de) | 2004-12-22 |
NZ535854A (en) | 2006-08-31 |
KR20040098023A (ko) | 2004-11-18 |
DK1487416T3 (da) | 2010-03-29 |
MXPA04009385A (es) | 2005-01-25 |
EP2085073A1 (de) | 2009-08-05 |
HK1069126A1 (en) | 2005-05-13 |
US20060141051A1 (en) | 2006-06-29 |
EP2085072A1 (de) | 2009-08-05 |
ATE450252T1 (de) | 2009-12-15 |
US20100092568A1 (en) | 2010-04-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60330322D1 (de) | Arzneimittel-mikroteilchen | |
EA200501586A1 (ru) | Фармацевтические продукты | |
BRPI0415858A (pt) | compostos de medicamentos terapêuticos modificados por tocoferol | |
DE60042076D1 (de) | Dosierung und verpackung für die kontrolierte abgabe von medikamenten | |
EE05506B1 (et) | Ravimi manustamise vahend eriti progestiinide jastrogeenide manustamiseks | |
NO20053224D0 (no) | Patient controlled drug administration device. | |
EP1611880A3 (de) | Pharmazeutische Zusammensetzungen zur sicheren Verabreichung von bei der Behandlung von Drogenabhängigkeit verwendeten Arzneimitteln | |
WO2004054542A3 (en) | Oral drug delivery system comprising high viscosity liquid carrier materials | |
WO2006060547A3 (en) | Systems and methods for intra-oral drug delivery | |
CY1107675T1 (el) | Φαρμακευτικα αλατα τραμαδολης | |
MXPA05010565A (es) | Sistemas de suminsitro de farmacos que comprenden un ingrediente activo encapsulado. | |
NO20055173L (no) | Farmasoytisk kombinasjonsblanding omfattende modafinil og et annet legemiddel | |
ATE356612T1 (de) | Orale, pharmazeutische darreichungsformen von flüssigen medikamenten mitverbesserter bioverfügbarkeit | |
ATE292453T1 (de) | Antivirale arznei | |
AU2003293593A8 (en) | Pharmaceutical preparations, use of said preparations and method for increasing the bioavailability of medicaments for peroral administration | |
DE60102590T2 (de) | Darreichungsformen zur behandlung von oralen mykosen | |
EA200600603A1 (ru) | Оральная система доставки лекарственного препарата | |
WO2005044186A3 (en) | Inhalable pharmaceutical formulations employing desiccating agents and methods of administering the same | |
BR0306843A (pt) | Formulações sedativas de não-benzodiazepina | |
DK1273301T3 (da) | Farmaceutiske præparater baseret på aktive bestanddele der kan anvendes til ulovlig administration | |
DE602004017164D1 (de) | Albuminkonjugate, die eine Glucuron-Verknüpfung enthalten | |
EP1603595A4 (de) | Pharmazeutische zusammensetzung zur behandlung von drogenabhängigkeit | |
NO20075508L (no) | Stannsoporfinpreparater og administrering | |
IL169687A0 (en) | Methods for the drug prophylaxis of poisoning by cholinesterase inhibitors, and active ingredients and medicaments suitable therefore | |
WO2003082342A1 (fr) | Utilisation du gene k1aa0172 pour le traitement et le diagnostic de maladies et decouverte de medicaments |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |