DE68900991D1 - Cyclosporin-zusammensetzungen. - Google Patents
Cyclosporin-zusammensetzungen.Info
- Publication number
- DE68900991D1 DE68900991D1 DE8989300856T DE68900991T DE68900991D1 DE 68900991 D1 DE68900991 D1 DE 68900991D1 DE 8989300856 T DE8989300856 T DE 8989300856T DE 68900991 T DE68900991 T DE 68900991T DE 68900991 D1 DE68900991 D1 DE 68900991D1
- Authority
- DE
- Germany
- Prior art keywords
- cyclosporin compositions
- cyclosporin
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1912588 | 1988-01-29 | ||
JP11163988 | 1988-05-10 | ||
JP63183127A JP2632010B2 (ja) | 1988-01-29 | 1988-07-22 | シクロスポリン製剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE68900991D1 true DE68900991D1 (de) | 1992-04-23 |
Family
ID=27282507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8989300856T Expired - Lifetime DE68900991D1 (de) | 1988-01-29 | 1989-01-27 | Cyclosporin-zusammensetzungen. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4990337A (de) |
EP (1) | EP0327280B1 (de) |
AU (1) | AU609242B2 (de) |
CA (1) | CA1326995C (de) |
DE (1) | DE68900991D1 (de) |
ES (1) | ES2033086T3 (de) |
GR (1) | GR3004611T3 (de) |
HK (1) | HK35697A (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
US6007840A (en) * | 1988-09-16 | 1999-12-28 | Novartis Ag | Pharmaceutical compositions comprising cyclosporins |
US5342625A (en) * | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
US7081445B2 (en) * | 1989-02-20 | 2006-07-25 | Novartis Ag | Cyclosporin galenic forms |
US5294604A (en) * | 1989-12-20 | 1994-03-15 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating ocular diseases by periocular administration of cyclosporine A or G |
DE69129918T2 (de) * | 1990-03-23 | 1999-02-04 | Yoshitomi Pharmaceutical | Ein in Wasser schwerlösliches Arzneimittel enthaltende pharmazeutische Zubereitung |
JPH06508029A (ja) * | 1991-05-17 | 1994-09-14 | カイロン コーポレイション | NF−↓kB転写活性化物質のインヒビター及びその使用 |
US6262022B1 (en) | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
EP0642332B1 (de) | 1992-05-13 | 1997-01-15 | Sandoz Ltd. | Opthalmische zusammensetzungen enthaltend ein cyclosporin |
EP1142568A1 (de) | 1992-09-25 | 2001-10-10 | Novartis AG | Pharmazeutische Zusammensetzungen mit Cyclosporine |
WO1994008538A1 (en) * | 1992-10-22 | 1994-04-28 | Aktsionernoe Obschestvo 'olvik' | Medicinal ocular membrane and method of producing the same |
CA2161143A1 (en) † | 1993-04-20 | 1994-10-27 | Monika Fleck | New pharmaceutical preparations comprising cyclosporin for oral administration |
US20020099067A1 (en) * | 1993-07-08 | 2002-07-25 | Ulrich Posanski | Pharmaceutical compositions for sparingly soluble therapeutic agents |
DE69426408T2 (de) * | 1993-09-28 | 2001-07-12 | Scherer Gmbh R P | Herstellung von Weichgelatinekapseln |
TW349870B (en) * | 1993-09-30 | 1999-01-11 | Janssen Pharmaceutica Nv | An antifungal pharmaceutical composition for oral administration and a process for the preparation thereof |
FR2711982B1 (fr) * | 1993-11-02 | 1996-01-19 | Saint Gobain Vitrage | Canal de transfert et de conditionnement de verre en fusion. |
US5952004A (en) * | 1994-03-18 | 1999-09-14 | Shire Laboratories Inc. | Emulsified drug delivery systems |
US5474979A (en) * | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
JP3833248B2 (ja) | 1994-11-03 | 2006-10-11 | ノバルティス・アクチエンゲゼルシャフト | 簡単な組成及び高い生物有効性を有する経口投与のためのシクロスポリンの新規処方物及びその製造法 |
US5824638A (en) * | 1995-05-22 | 1998-10-20 | Shire Laboratories, Inc. | Oral insulin delivery |
US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
US5766629A (en) * | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
EP0760237A1 (de) * | 1995-08-30 | 1997-03-05 | Cipla Limited | Öl-in-Wasser-Mikroemulsionen |
DE19544507B4 (de) | 1995-11-29 | 2007-11-15 | Novartis Ag | Cyclosporin enthaltende Präparate |
CZ288631B6 (cs) * | 1996-01-18 | 2001-08-15 | Galena, A. S. | Léčivé přípravky s obsahem cyklosporinu |
US5858401A (en) | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
US5660858A (en) * | 1996-04-03 | 1997-08-26 | Research Triangle Pharmaceuticals | Cyclosporin emulsions |
US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
PL192560B1 (pl) | 1996-08-22 | 2006-11-30 | Res Triangle Pharm Ltd | Sposób zmniejszania wielkości mikrocząstek i kompozycja zawierająca mikrocząstki |
US7255877B2 (en) * | 1996-08-22 | 2007-08-14 | Jagotec Ag | Fenofibrate microparticles |
SG115386A1 (en) | 1997-01-30 | 2005-10-28 | Novartis Ag | Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil |
DE19724605A1 (de) * | 1997-06-11 | 1998-12-17 | Sueddeutsche Kalkstickstoff | Hydrophile, homogene Monogycerid-Formulierungen und Verfahren zu deren Herstellung |
IN188719B (de) * | 1997-09-08 | 2002-11-02 | Panacea Biotec Ltd | |
US6187747B1 (en) | 1997-09-08 | 2001-02-13 | Panacea Biotech Limited | Pharmaceutical composition comprising cyclosporin |
US6008191A (en) * | 1997-09-08 | 1999-12-28 | Panacea Biotec Limited | Pharmaceutical compositions containing cyclosporin |
US6346511B1 (en) | 1997-09-08 | 2002-02-12 | Panacea Biotec Limited | Pharmaceutical composition comprising cyclosporin |
JP4761093B2 (ja) | 1997-12-10 | 2011-08-31 | シクロスポリン セラポイティクス リミテッド | オメガ−3脂肪酸油を含む医薬組成物 |
DE19810655A1 (de) * | 1998-03-12 | 1999-09-16 | Univ Eberhard Karls | Arzneimittel mit einem Gehalt an Ciclosporin |
US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
CA2333648C (en) | 1998-05-29 | 2008-10-21 | Rtp Pharma Inc. | Thermoprotected microparticle compositions and process for terminal steam sterilization thereof |
EP0976394A1 (de) * | 1998-07-30 | 2000-02-02 | Biosearch Italia S.p.A. | Neue injizierbare Formulierungen |
CN1287769C (zh) | 1998-11-20 | 2006-12-06 | 斯凯伊药品加拿大公司 | 可分散的磷脂稳定的微粒 |
IL143580A0 (en) | 1998-12-11 | 2002-04-21 | Pharmasolutions Inc | Pharmaceutical compositions containing lipophilic drugs and methods for the preparation thereof |
US6447806B1 (en) | 1999-02-25 | 2002-09-10 | Novartis Ag | Pharmaceutical compositions comprised of stabilized peptide particles |
US6057289A (en) * | 1999-04-30 | 2000-05-02 | Pharmasolutions, Inc. | Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system |
ATE296091T1 (de) * | 1999-09-21 | 2005-06-15 | Skyepharma Canada Inc | Oberflächenmodifizierte teilchenförmige zusammensetzungen biologisch aktiver stoffe |
US6720001B2 (en) | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
WO2001032143A1 (en) * | 1999-11-02 | 2001-05-10 | Cipla Ltd. | A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and a process for preparation thereof |
US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
GB0008785D0 (en) * | 2000-04-10 | 2000-05-31 | Novartis Ag | Organic compounds |
US20020058065A1 (en) * | 2000-09-20 | 2002-05-16 | Pol-Henri Guivarc'h | Insoluble drug particle compositions with improved fasted-fed effects |
US8586094B2 (en) * | 2000-09-20 | 2013-11-19 | Jagotec Ag | Coated tablets |
BR0213661A (pt) * | 2001-10-19 | 2004-10-26 | Isotechnika Inc | Pré-concentrado de microemulsão e método para seu preparo, formulação farmacêutica e método para seu preparo, método para produzir imuno, supressão, método para aumentar os efeitos imuno supressores de isatx247, uso de formulação farmacêutica |
US6979672B2 (en) | 2002-12-20 | 2005-12-27 | Polichem, S.A. | Cyclosporin-based pharmaceutical compositions |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
US7151085B2 (en) * | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
WO2006102157A1 (en) * | 2005-03-21 | 2006-09-28 | Ivax Pharmaceuticals S.R.O. | Crystallization inhibitor and its use in gelatin capsules |
GB2451811A (en) | 2007-08-09 | 2009-02-18 | Ems Sa | Delivery composition for solubilising water-insoluble pharmaceutical active ingredients |
PT2683406T (pt) | 2011-03-11 | 2019-07-08 | Beth Israel Deaconess Medical Ct Inc | Anticorpos anti-cd40 e utilização dos mesmos |
KR102479225B1 (ko) | 2014-09-26 | 2022-12-20 | 더 케무어스 컴퍼니 에프씨, 엘엘씨 | 설폰화 플루오르화, 비-플루오르화 또는 부분 플루오르화 우레탄 |
EP3307322B1 (de) | 2015-09-04 | 2021-02-17 | Primatope Therapeutics Inc. | Humanisierte anti-cd40-antikörper und verwendungen dafür |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE149197C (de) * | 1902-10-24 | |||
US2865859A (en) * | 1956-11-09 | 1958-12-23 | Irwin I Lubowe | Solubilizing of mineral, vegetable, animal oils for cosmetic, pharmaceutical and industrial purposes |
US3678149A (en) * | 1970-01-26 | 1972-07-18 | Samuel J Prigal | Method of enhancing the action of a medicament |
DE2907460A1 (de) * | 1978-03-07 | 1979-09-13 | Sandoz Ag | Neue resorbierbare galenische kompositionen |
CH641356A5 (en) * | 1979-02-27 | 1984-02-29 | Sandoz Ag | Pharmaceutical compositions containing cyclosporin |
JPS5921613A (ja) * | 1982-07-28 | 1984-02-03 | Takeda Chem Ind Ltd | 直腸投与製剤 |
EP0094157B1 (de) * | 1982-04-30 | 1987-07-29 | Takeda Chemical Industries, Ltd. | Pharmazeutische Zusammensetzung und ihre Verwendung |
US4659696A (en) * | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
US4474751A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Ophthalmic drug delivery system utilizing thermosetting gels |
BE897724A (fr) * | 1983-09-09 | 1984-01-02 | Mallien Denis | Systeme de communication selective, bidirectionnelle, par radio, entre un poste de commande et plusieurs postes de travail |
DE3339236A1 (de) * | 1983-10-28 | 1985-05-09 | Bayer Ag | Arzneimittelzubereitung |
US4612193A (en) * | 1983-12-23 | 1986-09-16 | Del Laboratories, Inc. | Sty ointment and method of using the same |
US4722914A (en) * | 1984-05-30 | 1988-02-02 | Motorola Inc. | Method of making a high density IC module assembly |
DE3580717D1 (de) * | 1984-08-02 | 1991-01-10 | Sandoz Ag | Pharmazeutische anwendung von (nva)2-cyclosporine. |
US4649047A (en) * | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
US4839342A (en) * | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
-
1989
- 1989-01-27 AU AU28853/89A patent/AU609242B2/en not_active Expired
- 1989-01-27 DE DE8989300856T patent/DE68900991D1/de not_active Expired - Lifetime
- 1989-01-27 ES ES198989300856T patent/ES2033086T3/es not_active Expired - Lifetime
- 1989-01-27 CA CA000589378A patent/CA1326995C/en not_active Expired - Lifetime
- 1989-01-27 EP EP89300856A patent/EP0327280B1/de not_active Expired
-
1990
- 1990-04-12 US US07/511,992 patent/US4990337A/en not_active Expired - Lifetime
-
1992
- 1992-05-18 GR GR920400935T patent/GR3004611T3/el unknown
-
1997
- 1997-03-20 HK HK35697A patent/HK35697A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4990337A (en) | 1991-02-05 |
ES2033086T3 (es) | 1993-03-01 |
CA1326995C (en) | 1994-02-15 |
AU2885389A (en) | 1989-08-03 |
GR3004611T3 (de) | 1993-04-28 |
EP0327280B1 (de) | 1992-03-18 |
AU609242B2 (en) | 1991-04-26 |
HK35697A (en) | 1997-03-27 |
EP0327280A1 (de) | 1989-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: NOVARTIS AG, BASEL, CH |
|
8328 | Change in the person/name/address of the agent |
Free format text: STREHL, SCHUEBEL-HOPF & PARTNER, 80538 MUENCHEN |