DE68900991D1 - Cyclosporin-zusammensetzungen. - Google Patents

Cyclosporin-zusammensetzungen.

Info

Publication number
DE68900991D1
DE68900991D1 DE8989300856T DE68900991T DE68900991D1 DE 68900991 D1 DE68900991 D1 DE 68900991D1 DE 8989300856 T DE8989300856 T DE 8989300856T DE 68900991 T DE68900991 T DE 68900991T DE 68900991 D1 DE68900991 D1 DE 68900991D1
Authority
DE
Germany
Prior art keywords
cyclosporin compositions
cyclosporin
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989300856T
Other languages
English (en)
Inventor
Kozo C O Sankyo Compa Kurihara
Masaru C O Sankyo Compa Murano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP63183127A external-priority patent/JP2632010B2/ja
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE68900991D1 publication Critical patent/DE68900991D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
DE8989300856T 1988-01-29 1989-01-27 Cyclosporin-zusammensetzungen. Expired - Lifetime DE68900991D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1912588 1988-01-29
JP11163988 1988-05-10
JP63183127A JP2632010B2 (ja) 1988-01-29 1988-07-22 シクロスポリン製剤

Publications (1)

Publication Number Publication Date
DE68900991D1 true DE68900991D1 (de) 1992-04-23

Family

ID=27282507

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989300856T Expired - Lifetime DE68900991D1 (de) 1988-01-29 1989-01-27 Cyclosporin-zusammensetzungen.

Country Status (8)

Country Link
US (1) US4990337A (de)
EP (1) EP0327280B1 (de)
AU (1) AU609242B2 (de)
CA (1) CA1326995C (de)
DE (1) DE68900991D1 (de)
ES (1) ES2033086T3 (de)
GR (1) GR3004611T3 (de)
HK (1) HK35697A (de)

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US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
DK0642332T3 (da) 1992-05-13 1997-06-16 Sandoz Ltd Ophthalmiske præparater indeholdende cyclosporin
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US20020099067A1 (en) * 1993-07-08 2002-07-25 Ulrich Posanski Pharmaceutical compositions for sparingly soluble therapeutic agents
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US5824638A (en) * 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
EP0760237A1 (de) * 1995-08-30 1997-03-05 Cipla Limited Öl-in-Wasser-Mikroemulsionen
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
CZ288631B6 (cs) * 1996-01-18 2001-08-15 Galena, A. S. Léčivé přípravky s obsahem cyklosporinu
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US5660858A (en) * 1996-04-03 1997-08-26 Research Triangle Pharmaceuticals Cyclosporin emulsions
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
JP2000516244A (ja) 1996-08-22 2000-12-05 リサーチ・トライアングル・ファーマシューティカルズ 水不溶性物質の微粒子を含む組成物およびその製造方法
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
CA2278675A1 (en) * 1997-01-30 1998-08-06 Novartis Ag Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil
DE19724605A1 (de) * 1997-06-11 1998-12-17 Sueddeutsche Kalkstickstoff Hydrophile, homogene Monogycerid-Formulierungen und Verfahren zu deren Herstellung
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
IN188719B (de) * 1997-09-08 2002-11-02 Panacea Biotec Ltd
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
CA2313024C (en) 1997-12-10 2008-06-03 Severson, Mary L. Pharmaceutical compositions containing an omega-3 fatty acid oil
DE19810655A1 (de) * 1998-03-12 1999-09-16 Univ Eberhard Karls Arzneimittel mit einem Gehalt an Ciclosporin
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
EP1079808B1 (de) 1998-05-29 2004-02-11 Skyepharma Canada Inc. Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
EP0976394A1 (de) * 1998-07-30 2000-02-02 Biosearch Italia S.p.A. Neue injizierbare Formulierungen
CZ20011739A3 (cs) 1998-11-20 2001-10-17 Rtp Pharma Inc. Dispergovatelné fosfolipidem stabilizované mikročástice
IL143580A0 (en) 1998-12-11 2002-04-21 Pharmasolutions Inc Pharmaceutical compositions containing lipophilic drugs and methods for the preparation thereof
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
US6057289A (en) * 1999-04-30 2000-05-02 Pharmasolutions, Inc. Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system
ES2241663T3 (es) * 1999-09-21 2005-11-01 Skyepharma Canada Inc. Composiciones particuladas modificadas superficialmente de substancias biologicamente activas.
US6720001B2 (en) 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
AU2127400A (en) * 1999-11-02 2001-05-14 Cipla Limited A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and process for preparation thereof
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
GB0008785D0 (en) * 2000-04-10 2000-05-31 Novartis Ag Organic compounds
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
CA2423336C (en) * 2000-09-20 2011-03-08 Rtp Pharma Inc. Stabilised fibrate microparticles
RU2317067C2 (ru) * 2001-10-19 2008-02-20 Изотехника Инк. Микроэмульсионный предконцентрат аналога циклоспорина
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US7151085B2 (en) 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
US8673351B2 (en) 2005-03-21 2014-03-18 Ivax Pharmaceuticals S.R.O. Crystallization inhibitor and its use in gelatin capsules
GB2451811A (en) 2007-08-09 2009-02-18 Ems Sa Delivery composition for solubilising water-insoluble pharmaceutical active ingredients
AU2012229236B2 (en) 2011-03-11 2017-05-18 Beth Israel Deaconess Medical Center, Inc. Anti-CD40 antibodies and uses thereof
EP3197865A1 (de) 2014-09-26 2017-08-02 The Chemours Company FC, LLC Sulfonierte fluorierte, nichtfluorierte oder teilweise fluorierte urethane
EP3906943A1 (de) 2015-09-04 2021-11-10 Primatope Therapeutics Inc. Humanisierte anti-cd40-antikörper und verwendungen dafür

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DE149197C (de) * 1902-10-24
US2865859A (en) * 1956-11-09 1958-12-23 Irwin I Lubowe Solubilizing of mineral, vegetable, animal oils for cosmetic, pharmaceutical and industrial purposes
US3678149A (en) * 1970-01-26 1972-07-18 Samuel J Prigal Method of enhancing the action of a medicament
SE445174B (sv) * 1978-03-07 1986-06-09 Sandoz Ag Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans
CH641356A5 (en) * 1979-02-27 1984-02-29 Sandoz Ag Pharmaceutical compositions containing cyclosporin
JPS5921613A (ja) * 1982-07-28 1984-02-03 Takeda Chem Ind Ltd 直腸投与製剤
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
EP0094157B1 (de) * 1982-04-30 1987-07-29 Takeda Chemical Industries, Ltd. Pharmazeutische Zusammensetzung und ihre Verwendung
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
BE897724A (fr) * 1983-09-09 1984-01-02 Mallien Denis Systeme de communication selective, bidirectionnelle, par radio, entre un poste de commande et plusieurs postes de travail
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
US4612193A (en) * 1983-12-23 1986-09-16 Del Laboratories, Inc. Sty ointment and method of using the same
US4722914A (en) * 1984-05-30 1988-02-02 Motorola Inc. Method of making a high density IC module assembly
DE3580717D1 (de) * 1984-08-02 1991-01-10 Sandoz Ag Pharmazeutische anwendung von (nva)2-cyclosporine.
US4649047A (en) * 1985-03-19 1987-03-10 University Of Georgia Research Foundation, Inc. Ophthalmic treatment by topical administration of cyclosporin
US4839342A (en) * 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin

Also Published As

Publication number Publication date
EP0327280A1 (de) 1989-08-09
EP0327280B1 (de) 1992-03-18
AU2885389A (en) 1989-08-03
US4990337A (en) 1991-02-05
GR3004611T3 (de) 1993-04-28
HK35697A (en) 1997-03-27
ES2033086T3 (es) 1993-03-01
AU609242B2 (en) 1991-04-26
CA1326995C (en) 1994-02-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH

8328 Change in the person/name/address of the agent

Free format text: STREHL, SCHUEBEL-HOPF & PARTNER, 80538 MUENCHEN