DE68903688T2 - Biosensoren. - Google Patents

Biosensoren.

Info

Publication number
DE68903688T2
DE68903688T2 DE8989305574T DE68903688T DE68903688T2 DE 68903688 T2 DE68903688 T2 DE 68903688T2 DE 8989305574 T DE8989305574 T DE 8989305574T DE 68903688 T DE68903688 T DE 68903688T DE 68903688 T2 DE68903688 T2 DE 68903688T2
Authority
DE
Germany
Prior art keywords
layer
refractive index
membrane
sample
strength
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989305574T
Other languages
English (en)
Other versions
DE68903688D1 (de
Inventor
Martin Francis Finlan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Amersham International PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham International PLC filed Critical Amersham International PLC
Application granted granted Critical
Publication of DE68903688D1 publication Critical patent/DE68903688D1/de
Publication of DE68903688T2 publication Critical patent/DE68903688T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/110833Utilizing a moving indicator strip or tape
DE8989305574T 1988-06-06 1989-06-02 Biosensoren. Expired - Fee Related DE68903688T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888813307A GB8813307D0 (en) 1988-06-06 1988-06-06 Biological sensors

Publications (2)

Publication Number Publication Date
DE68903688D1 DE68903688D1 (de) 1993-01-14
DE68903688T2 true DE68903688T2 (de) 1993-04-01

Family

ID=10638127

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989305574T Expired - Fee Related DE68903688T2 (de) 1988-06-06 1989-06-02 Biosensoren.

Country Status (6)

Country Link
US (1) US5055265A (de)
EP (1) EP0346016B1 (de)
JP (1) JPH0244230A (de)
AT (1) ATE83076T1 (de)
DE (1) DE68903688T2 (de)
GB (1) GB8813307D0 (de)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US5478755A (en) * 1988-07-25 1995-12-26 Ares Serono Research & Development Ltd. Long range surface plasma resonance immunoassay
GB8817710D0 (en) * 1988-07-25 1988-09-01 Ares Serono Res & Dev Ltd Method of assay
GB2247749A (en) * 1990-09-05 1992-03-11 Marconi Gec Ltd Sensor utilising surface plasmon resonance
GB9102646D0 (en) * 1991-02-07 1991-03-27 Fisons Plc Analytical device
DE69110032T2 (de) * 1991-06-08 1995-12-21 Hewlett Packard Gmbh Verfahren und Gerät zur Feststellung und/oder Konzentrationsbestimmung von Biomolekülen.
JP2721616B2 (ja) * 1992-05-26 1998-03-04 株式会社日立製作所 減衰全反射プリズムを用いた赤外スペクトル測定法
JPH05340865A (ja) * 1992-06-09 1993-12-24 Canon Inc 測定装置
CN1035789C (zh) * 1992-06-20 1997-09-03 中国科学院长春应用化学研究所 现场显微红外光谱电化学分析系统
US5395587A (en) * 1993-07-06 1995-03-07 Smithkline Beecham Corporation Surface plasmon resonance detector having collector for eluted ligate
WO1995006138A1 (en) * 1993-08-25 1995-03-02 The Regents Of The University Of California Microscopic method for detecting micromotions
GB9320305D0 (en) * 1993-10-01 1993-11-17 Kodak Ltd Production of carriers for surface plasmin resonance
GB9320310D0 (en) * 1993-10-01 1993-11-17 Kodak Ltd Production of carriers for surface plasmon resonance
US5955153A (en) * 1993-10-01 1999-09-21 Johnson & Johnson Clinical Diagnostics, Inc. Production of carriers for surface plasmon resonance
GB9414599D0 (en) * 1994-07-20 1994-09-07 Scient Generics Ltd Biosensor
US5606633A (en) * 1995-06-26 1997-02-25 American Research Corporation Of Virginia Chemical detector employing surface plasmon resonance excited using an optical waveguide configured as an asymmetric waveguide coupler
US5858799A (en) * 1995-10-25 1999-01-12 University Of Washington Surface plasmon resonance chemical electrode
US5815278A (en) * 1995-10-25 1998-09-29 University Of Washington Surface plasmon resonance light pipe sensing probe and related interface optics
US5917607A (en) * 1996-04-25 1999-06-29 Fuji Photo Film Co., Ltd. Surface plasmon sensor for multiple channel analysis
US5852229A (en) * 1996-05-29 1998-12-22 Kimberly-Clark Worldwide, Inc. Piezoelectric resonator chemical sensing device
US6020047A (en) * 1996-09-04 2000-02-01 Kimberly-Clark Worldwide, Inc. Polymer films having a printed self-assembling monolayer
US5846843A (en) * 1996-11-18 1998-12-08 The University Of Toledo Sensor using long range surface plasmon resonance with diffraction double-grating
US5922550A (en) * 1996-12-18 1999-07-13 Kimberly-Clark Worldwide, Inc. Biosensing devices which produce diffraction images
US6048623A (en) * 1996-12-18 2000-04-11 Kimberly-Clark Worldwide, Inc. Method of contact printing on gold coated films
US5776785A (en) * 1996-12-30 1998-07-07 Diagnostic Products Corporation Method and apparatus for immunoassay using fluorescent induced surface plasma emission
JP3399804B2 (ja) * 1997-02-26 2003-04-21 富士写真フイルム株式会社 表面プラズモンセンサー
US6180288B1 (en) 1997-03-21 2001-01-30 Kimberly-Clark Worldwide, Inc. Gel sensors and method of use thereof
EP0988517A4 (de) * 1997-06-10 2003-03-19 Calspan Corp Nachweis chemisch aktiver materialien mit hilfe eines saugfähigen polymers und eines fluoreszenznachweismittels
US6060256A (en) * 1997-12-16 2000-05-09 Kimberly-Clark Worldwide, Inc. Optical diffraction biosensor
US6368795B1 (en) 1998-02-02 2002-04-09 Signature Bioscience, Inc. Bio-assay device and test system for detecting molecular binding events
US6338968B1 (en) 1998-02-02 2002-01-15 Signature Bioscience, Inc. Method and apparatus for detecting molecular binding events
US6395480B1 (en) 1999-02-01 2002-05-28 Signature Bioscience, Inc. Computer program and database structure for detecting molecular binding events
US7640083B2 (en) 2002-11-22 2009-12-29 Monroe David A Record and playback system for aircraft
US6300638B1 (en) 1998-11-12 2001-10-09 Calspan Srl Corporation Modular probe for total internal reflection fluorescence spectroscopy
US6221579B1 (en) * 1998-12-11 2001-04-24 Kimberly-Clark Worldwide, Inc. Patterned binding of functionalized microspheres for optical diffraction-based biosensors
US6579673B2 (en) 1998-12-17 2003-06-17 Kimberly-Clark Worldwide, Inc. Patterned deposition of antibody binding protein for optical diffraction-based biosensors
US6480282B1 (en) 1999-05-06 2002-11-12 University Of Washington Capillary surface plasmon resonance sensors and multisensors
JP2003507723A (ja) * 1999-08-19 2003-02-25 ザ・リージェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア カンチレバーアレイブロックのパレットにより微小力を可視的に識別する装置及び方法
JP2001066248A (ja) * 1999-08-26 2001-03-16 Fuji Photo Film Co Ltd 表面プラズモンセンサー
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US6458326B1 (en) 1999-11-24 2002-10-01 Home Diagnostics, Inc. Protective test strip platform
US6399295B1 (en) 1999-12-17 2002-06-04 Kimberly-Clark Worldwide, Inc. Use of wicking agent to eliminate wash steps for optical diffraction-based biosensors
US6728429B1 (en) 2000-02-16 2004-04-27 Biotell, Inc. Optical detection
JP4368535B2 (ja) * 2000-05-11 2009-11-18 富士フイルム株式会社 測定チップ
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
US6885454B2 (en) * 2001-03-28 2005-04-26 Fuji Photo Film Co., Ltd. Measuring apparatus
DE10145719A1 (de) * 2001-09-17 2003-04-10 Inst Chemo Biosensorik Optischer Wasserstoff-Sensor und Verfahren zur Erfassung von Wasserstoff
GR1004178B (el) 2001-11-29 2003-03-05 "����������" Ολοκληρωμενος οπτοηλεκτρονικος βιοαισθητηρας πυριτιου για ανιχνευση βιομοριων επισημασμενων με χρωμοφορες ομαδες ή νανοσωματιδια
US7098041B2 (en) 2001-12-11 2006-08-29 Kimberly-Clark Worldwide, Inc. Methods to view and analyze the results from diffraction-based diagnostics
US7102752B2 (en) 2001-12-11 2006-09-05 Kimberly-Clark Worldwide, Inc. Systems to view and analyze the results from diffraction-based diagnostics
US8367013B2 (en) 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US20030154149A1 (en) * 2002-02-13 2003-08-14 Dilip Gajendragadkar System and method of creating and executing a restricted stock sale plan
US6791690B2 (en) * 2002-04-30 2004-09-14 Agilent Technologies, Inc. Reading dry chemical arrays
US7118855B2 (en) * 2002-05-03 2006-10-10 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7485453B2 (en) * 2002-05-03 2009-02-03 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7214530B2 (en) 2002-05-03 2007-05-08 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices
US7223534B2 (en) 2002-05-03 2007-05-29 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7223368B2 (en) 2002-05-03 2007-05-29 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7771922B2 (en) 2002-05-03 2010-08-10 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic device
US7091049B2 (en) 2002-06-26 2006-08-15 Kimberly-Clark Worldwide, Inc. Enhanced diffraction-based biosensor devices
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7314763B2 (en) 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7169550B2 (en) * 2002-09-26 2007-01-30 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7122384B2 (en) * 2002-11-06 2006-10-17 E. I. Du Pont De Nemours And Company Resonant light scattering microparticle methods
US7344678B2 (en) * 2002-11-15 2008-03-18 The Regents Of The University Of California Composite sensor membrane
WO2004046681A2 (en) * 2002-11-18 2004-06-03 Vir A/S Dispersion compensating biosensor
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
WO2005012886A1 (en) * 2003-03-27 2005-02-10 Corning Incorporated Label-free evanescent-field detection of biological and chemical agents
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US20050112587A1 (en) * 2003-11-25 2005-05-26 Sherrill James V. Analyzing biological probes
WO2005052557A1 (en) * 2003-11-28 2005-06-09 Lumiscence A/S An examination system for examination of a specimen; sub-units and units therefore, a sensor and a microscope
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7796266B2 (en) 2004-04-30 2010-09-14 Kimberly-Clark Worldwide, Inc. Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US7815854B2 (en) 2004-04-30 2010-10-19 Kimberly-Clark Worldwide, Inc. Electroluminescent illumination source for optical detection systems
WO2005120361A1 (ja) * 2004-06-10 2005-12-22 Matsushita Electric Industrial Co., Ltd. 生体情報測定装置、標準素子、及び生体情報測定装置の使用方法
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US7187446B2 (en) * 2004-07-26 2007-03-06 Fuji Photo Film Co., Ltd. Measuring apparatus
KR100723401B1 (ko) * 2005-01-29 2007-05-30 삼성전자주식회사 나노 크기의 다공성 재료를 이용한 표면 플라즈몬 공명소자 및 그 제조방법
US7818350B2 (en) 2005-02-28 2010-10-19 Yahoo! Inc. System and method for creating a collaborative playlist
US7611908B2 (en) 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
US7749445B2 (en) 2005-05-02 2010-07-06 Bioscale, Inc. Method and apparatus for analyzing bioprocess fluids
US7648844B2 (en) 2005-05-02 2010-01-19 Bioscale, Inc. Method and apparatus for detection of analyte using an acoustic device
US7300631B2 (en) 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
CN100401041C (zh) * 2005-06-09 2008-07-09 上海交通大学 光波导吸收式气体传感器及测量系统
JP4676402B2 (ja) * 2006-08-29 2011-04-27 シャープ株式会社 分子検出装置及び分子検出装置を用いた洗浄装置
US7949210B2 (en) * 2006-10-09 2011-05-24 Colorado School Of Mines Silicon-compatible surface plasmon optical elements
KR100860701B1 (ko) * 2007-03-14 2008-09-26 한양대학교 산학협력단 장거리 표면 플라즈몬 이중 금속 광도파로 센서
WO2009033056A1 (en) 2007-09-06 2009-03-12 Bioscale, Inc. Reusable detection surfaces and methods of using same
CN101246123B (zh) * 2008-01-04 2012-03-14 清华大学 一种长程表面等离子波折射率检测芯片
JP2012163497A (ja) * 2011-02-08 2012-08-30 Kobe Steel Ltd 表面プラズモン共鳴測定用チップ
CN102183507B (zh) * 2011-03-01 2012-11-21 吉林大学 一种长程表面等离子体激励表面增强拉曼散射的方法
US8953168B2 (en) * 2012-06-08 2015-02-10 City University Of Hong Kong Optical sensing devices and methods for detecting samples using the same
CN104697961A (zh) * 2014-12-15 2015-06-10 天津科技大学 长程表面等离子体共振传感器及制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526480A (en) * 1966-12-15 1970-09-01 Xerox Corp Automated chemical analyzer
GB1451449A (en) * 1972-10-09 1976-10-06 Bagshawe K D Chemical and biological analysis
FR2565350B1 (fr) * 1984-06-05 1986-10-10 Paris Nord Universite Moyens propres a permettre le support, le traitement, le stockage et l'analyse automatiques en continu d'echantillons biologiques
GB8509491D0 (en) * 1985-04-12 1985-05-15 Plessey Co Plc Optic waveguide biosensors
GB8509492D0 (en) * 1985-04-12 1985-05-15 Plessey Co Plc Optical assay
GB2197065A (en) * 1986-11-03 1988-05-11 Stc Plc Optical sensor device

Also Published As

Publication number Publication date
JPH0244230A (ja) 1990-02-14
EP0346016A2 (de) 1989-12-13
US5055265A (en) 1991-10-08
ATE83076T1 (de) 1992-12-15
EP0346016B1 (de) 1992-12-02
EP0346016A3 (en) 1990-09-19
GB8813307D0 (en) 1988-07-13
DE68903688D1 (de) 1993-01-14

Similar Documents

Publication Publication Date Title
ATE83076T1 (de) Biosensoren.
US5415842A (en) Surface plasmon resonance analytical device
USRE37473E1 (en) Diffraction anomaly sensor having grating coated with protective dielectric layer
Gupta et al. Fiber optic sensors based on plasmonics
EP0205236B1 (de) Messfühler für biologische Moleküle mit Verwendung optischer Wellenleiter
US5622868A (en) Analytical apparatus utilizing a colorimetric or other optically detectable effect
US4844613A (en) Optical surface plasmon sensor device
FI85768B (fi) Foerfarande foer utfoerning av ytplasmonresonansmaetning samt i foerfarandet anvaendbar givare.
Niggemann et al. Remote sensing of tetrachloroethene with a micro-fibre optical gas sensor based on surface plasmon resonance spectroscopy
DE68903785D1 (de) Biosensoren.
FI883868A0 (fi) Anturi biologista, biokemiallista ja kemiallista koestusta varten
GB2173895A (en) Optical assay
Goddard et al. Real-time biomolecular interaction analysis using the resonant mirror sensor
Sloper et al. A planar indium phosphate monomode waveguide evanescent field immunosensor
WO1988007202A1 (en) Improved assay technique and apparatus therefor
ES2087183T3 (es) Sistema de analisis y procedimiento para la determinacion de un analito en una muestra fluida.
GB2197068A (en) Optical sensor device
Akimoto et al. A surface plasmon resonance probe with a novel integrated reference sensor surface
CN101294900A (zh) 高精细度腔表面等离子体共振传感装置
JPH09257699A (ja) 表面プラズモン共鳴センサ装置
JPH01263537A (ja) ファイバー状センサおよびその評価装置
CN1987425A (zh) 表面电浆共振感测系统及方法
Narayanaswamy et al. Surface plasmon resonance biosensors for food safety
Dougherty A compact optoelectronic instrument with a disposable sensor based on surface plasmon resonance
WO1990008952A1 (en) Sensor

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee