DE68912882T2 - Wirkstoff-Harzkomplexe mit verzögerter Freigabe. - Google Patents

Wirkstoff-Harzkomplexe mit verzögerter Freigabe.

Info

Publication number
DE68912882T2
DE68912882T2 DE68912882T DE68912882T DE68912882T2 DE 68912882 T2 DE68912882 T2 DE 68912882T2 DE 68912882 T DE68912882 T DE 68912882T DE 68912882 T DE68912882 T DE 68912882T DE 68912882 T2 DE68912882 T2 DE 68912882T2
Authority
DE
Germany
Prior art keywords
drug
active ingredient
delayed release
resin complexes
ingredient resin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68912882T
Other languages
English (en)
Other versions
DE68912882D1 (de
Inventor
William Joseph Kelleher
Anthony Earl Carpanzano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Vicks Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Vicks Inc filed Critical Richardson Vicks Inc
Application granted granted Critical
Publication of DE68912882D1 publication Critical patent/DE68912882D1/de
Publication of DE68912882T2 publication Critical patent/DE68912882T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
DE68912882T 1988-11-02 1989-10-31 Wirkstoff-Harzkomplexe mit verzögerter Freigabe. Expired - Fee Related DE68912882T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/265,910 US4996047A (en) 1988-11-02 1988-11-02 Sustained release drug-resin complexes

Publications (2)

Publication Number Publication Date
DE68912882D1 DE68912882D1 (de) 1994-03-17
DE68912882T2 true DE68912882T2 (de) 1994-06-01

Family

ID=23012384

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68912882T Expired - Fee Related DE68912882T2 (de) 1988-11-02 1989-10-31 Wirkstoff-Harzkomplexe mit verzögerter Freigabe.

Country Status (11)

Country Link
US (1) US4996047A (de)
EP (1) EP0367746B1 (de)
JP (1) JP2941314B2 (de)
AT (1) ATE101033T1 (de)
AU (1) AU638420B2 (de)
CA (1) CA2001859C (de)
DE (1) DE68912882T2 (de)
DK (1) DK175659B1 (de)
IE (1) IE62765B1 (de)
NZ (1) NZ231229A (de)
PH (1) PH26699A (de)

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Also Published As

Publication number Publication date
EP0367746A2 (de) 1990-05-09
NZ231229A (en) 1992-03-26
DK546389A (da) 1990-05-03
DK546389D0 (da) 1989-11-02
DK175659B1 (da) 2005-01-10
CA2001859A1 (en) 1990-04-02
AU638420B2 (en) 1993-07-01
JP2941314B2 (ja) 1999-08-25
EP0367746A3 (de) 1991-01-23
IE62765B1 (en) 1995-02-22
US4996047A (en) 1991-02-26
DE68912882D1 (de) 1994-03-17
AU4430689A (en) 1990-05-10
ATE101033T1 (de) 1994-02-15
IE893537L (en) 1990-05-02
EP0367746B1 (de) 1994-02-02
CA2001859C (en) 1995-10-31
JPH02172912A (ja) 1990-07-04
PH26699A (en) 1992-09-14

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