DE68915132T2 - Verfahren zur Behandlung von Periodontitis durch protrahierte Wirkstoffabgabe von Arzneimitteln in der Zahnhöhle, Zusammensetzung davon und Vorrichtung zur Verabreichung. - Google Patents

Verfahren zur Behandlung von Periodontitis durch protrahierte Wirkstoffabgabe von Arzneimitteln in der Zahnhöhle, Zusammensetzung davon und Vorrichtung zur Verabreichung.

Info

Publication number
DE68915132T2
DE68915132T2 DE68915132T DE68915132T DE68915132T2 DE 68915132 T2 DE68915132 T2 DE 68915132T2 DE 68915132 T DE68915132 T DE 68915132T DE 68915132 T DE68915132 T DE 68915132T DE 68915132 T2 DE68915132 T2 DE 68915132T2
Authority
DE
Germany
Prior art keywords
administration
periodontitis
treatment
composition
drug delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68915132T
Other languages
English (en)
Other versions
DE68915132D1 (de
Inventor
Nancy Susan Brizzolara
Michael Gerard Lanzilotti
James Ronald Lawter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DE68915132D1 publication Critical patent/DE68915132D1/de
Application granted granted Critical
Publication of DE68915132T2 publication Critical patent/DE68915132T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
DE68915132T 1988-12-22 1989-11-27 Verfahren zur Behandlung von Periodontitis durch protrahierte Wirkstoffabgabe von Arzneimitteln in der Zahnhöhle, Zusammensetzung davon und Vorrichtung zur Verabreichung. Expired - Lifetime DE68915132T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28907688A 1988-12-22 1988-12-22

Publications (2)

Publication Number Publication Date
DE68915132D1 DE68915132D1 (de) 1994-06-09
DE68915132T2 true DE68915132T2 (de) 1994-12-08

Family

ID=23109956

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68915132T Expired - Lifetime DE68915132T2 (de) 1988-12-22 1989-11-27 Verfahren zur Behandlung von Periodontitis durch protrahierte Wirkstoffabgabe von Arzneimitteln in der Zahnhöhle, Zusammensetzung davon und Vorrichtung zur Verabreichung.

Country Status (16)

Country Link
US (1) US5366733A (de)
EP (1) EP0374531B1 (de)
JP (1) JP2901674B2 (de)
KR (2) KR0138651B1 (de)
AT (1) ATE105177T1 (de)
AU (1) AU635912B2 (de)
CA (1) CA2006105C (de)
DE (1) DE68915132T2 (de)
DK (1) DK174915B1 (de)
ES (1) ES2051968T3 (de)
IE (1) IE63952B1 (de)
IL (1) IL92700A (de)
NO (1) NO178605C (de)
NZ (1) NZ231791A (de)
PT (1) PT92614B (de)
ZA (1) ZA899857B (de)

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* Cited by examiner, † Cited by third party
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DE10018221A1 (de) * 2000-04-12 2001-11-22 Fitzner Lothar Verwendung von Wachstumshormonen zur therapeutischen Behandlung von Zähnen, Zahnfleisch oder Kieferknochen

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US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
US6153210A (en) * 1997-08-14 2000-11-28 Periodontix, Inc. Use of locally delivered metal ions for treatment of periodontal disease
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
WO1999066797A1 (en) 1998-06-22 1999-12-29 Worden Charles E Enriched platelet wound healant
US20050037086A1 (en) * 1999-11-19 2005-02-17 Zycos Inc., A Delaware Corporation Continuous-flow method for preparing microparticles
US20040142475A1 (en) * 2000-06-02 2004-07-22 Barman Shikha P. Delivery systems for bioactive agents
JP2002128697A (ja) * 2000-10-20 2002-05-09 Nonomura Tomosuke 口腔治療予防剤
US6576226B1 (en) * 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline
US20040029842A1 (en) * 2001-12-18 2004-02-12 Gardner Wallace J. Triglyceride lowering, common cold and pneumonia prevention composition comprising tetracycline, and methods of treating or preventing diseases using same
US6682348B2 (en) 2002-03-29 2004-01-27 Orapharma, Inc. Dispensing apparatus and cartridge
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
ATE510605T1 (de) 2003-03-14 2011-06-15 Univ Columbia Systeme und verfahren für auf blut basierende therapien mit einer membranlosen mikrofluid- austauschvorrichtung
US20060076295A1 (en) 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
US20040185009A1 (en) * 2003-03-19 2004-09-23 Dexcel Pharma Technologies Ltd. Composition and device for treating periodontal diseases
US7309232B2 (en) * 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
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MX2008014732A (es) 2006-05-22 2009-04-07 Univ Columbia Sistemas y metodos de intercambio sin membrana microfluidica usando filtracion de corrientes de salida de fluidos de extraccion.
US20090081135A1 (en) * 2007-09-24 2009-03-26 Glen Jeffrey D Iodine-based oral antibacterial treatment methodology
US7976489B2 (en) 2007-12-04 2011-07-12 Orapharma, Inc. Device for delivering medicinal implants
US7976490B2 (en) * 2007-12-04 2011-07-12 Orapharma, Inc. Medicinal implant cartridge
US7976491B2 (en) * 2007-12-04 2011-07-12 Orapharma, Inc. Actuators for device for delivering medicinal implants
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US8048021B2 (en) * 2008-12-02 2011-11-01 Orapharma, Inc. Medicinal implant device and cartridge
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US8865198B2 (en) 2010-10-25 2014-10-21 Dexcel Pharma Technologies Ltd. Method for treating a periodontal disease
US20130005593A1 (en) * 2011-03-09 2013-01-03 Teles Flavia R F RNA-Oligonucleotide Quantification Technique for the Enumeration of Uncultivated Bacterial Species
US9402701B2 (en) 2013-10-22 2016-08-02 Profounda, Inc Positionable delivery device and method
US11147747B2 (en) * 2018-04-05 2021-10-19 Terrell F. Pannkuk Composition and method for endodontic debridement
US11571367B2 (en) * 2018-04-05 2023-02-07 Terrell F. Pannkuk Composition and method for endodontic debridement

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Publication number Priority date Publication date Assignee Title
DE10018221A1 (de) * 2000-04-12 2001-11-22 Fitzner Lothar Verwendung von Wachstumshormonen zur therapeutischen Behandlung von Zähnen, Zahnfleisch oder Kieferknochen

Also Published As

Publication number Publication date
US5366733A (en) 1994-11-22
EP0374531B1 (de) 1994-05-04
AU635912B2 (en) 1993-04-08
DK655889A (da) 1990-06-23
IE63952B1 (en) 1995-06-28
IL92700A (en) 1994-05-30
NO895167D0 (no) 1989-12-21
DE68915132D1 (de) 1994-06-09
IE894145L (en) 1990-06-22
KR900009061A (ko) 1990-07-02
NO178605C (no) 1996-05-02
PT92614B (pt) 1995-09-12
DK655889D0 (da) 1989-12-21
EP0374531A3 (de) 1991-07-31
ZA899857B (en) 1990-10-31
EP0374531A2 (de) 1990-06-27
NO178605B (no) 1996-01-22
DK174915B1 (da) 2004-02-23
CA2006105A1 (en) 1990-06-22
ATE105177T1 (de) 1994-05-15
NO895167L (no) 1990-06-25
PT92614A (pt) 1990-06-29
IL92700A0 (en) 1990-09-17
KR0143912B1 (ko) 1998-07-15
KR0138651B1 (ko) 1998-05-15
NZ231791A (en) 1992-05-26
JPH02184620A (ja) 1990-07-19
KR900009045A (ko) 1990-07-02
JP2901674B2 (ja) 1999-06-07
CA2006105C (en) 2000-03-14
AU4707789A (en) 1990-06-28
ES2051968T3 (es) 1994-07-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: WYETH HOLDINGS CORP., MADISON, N.J., US