DE68922844D1 - Agglutinationsverfahren zur Bestimmung von mehreren Liganden. - Google Patents
Agglutinationsverfahren zur Bestimmung von mehreren Liganden.Info
- Publication number
- DE68922844D1 DE68922844D1 DE68922844T DE68922844T DE68922844D1 DE 68922844 D1 DE68922844 D1 DE 68922844D1 DE 68922844 T DE68922844 T DE 68922844T DE 68922844 T DE68922844 T DE 68922844T DE 68922844 D1 DE68922844 D1 DE 68922844D1
- Authority
- DE
- Germany
- Prior art keywords
- specimen
- beads
- ligands
- determination
- bead
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8814420A FR2638848B1 (fr) | 1988-11-04 | 1988-11-04 | Procede de detection et/ou de dosage dans un milieu liquide ou semi-liquide d'au moins une substance organique, biologique ou medicamenteuse soluble, par une methode d'agglutination |
PCT/FR1989/000573 WO1990005307A1 (fr) | 1988-11-04 | 1989-11-03 | Methode d'agglutination pour l'analyse d'une substance |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68922844D1 true DE68922844D1 (de) | 1995-06-29 |
DE68922844T2 DE68922844T2 (de) | 1995-12-21 |
Family
ID=9371582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68922844T Expired - Fee Related DE68922844T2 (de) | 1988-11-04 | 1989-11-03 | Agglutinationsverfahren zur Bestimmung von mehreren Liganden. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5219763A (de) |
EP (1) | EP0397828B1 (de) |
JP (1) | JPH03502246A (de) |
AT (1) | ATE123150T1 (de) |
AU (1) | AU4518689A (de) |
DE (1) | DE68922844T2 (de) |
FR (1) | FR2638848B1 (de) |
WO (1) | WO1990005307A1 (de) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5547839A (en) * | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
JPH03225277A (ja) * | 1990-01-31 | 1991-10-04 | Fujirebio Inc | 多項目の免疫化学的測定法 |
DE69132843T2 (de) * | 1990-12-06 | 2002-09-12 | Affymetrix Inc N D Ges D Staat | Identifizierung von Nukleinsäuren in Proben |
WO1994007138A1 (en) | 1992-09-14 | 1994-03-31 | Fodstad Oystein | Detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations |
US5561045A (en) * | 1994-01-04 | 1996-10-01 | Intracel Corporation | Detection reagent, article, and immunoassay method |
NO180658C (no) | 1994-03-10 | 1997-05-21 | Oeystein Fodstad | Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner |
US6159748A (en) * | 1995-03-13 | 2000-12-12 | Affinitech, Ltd | Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry |
US5981180A (en) * | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
US5736330A (en) * | 1995-10-11 | 1998-04-07 | Luminex Corporation | Method and compositions for flow cytometric determination of DNA sequences |
AU7398996A (en) | 1995-10-11 | 1997-04-30 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
NO961031D0 (no) | 1996-03-13 | 1996-03-13 | Det Norske Radiumshospital Tum | Fremgangsmåte til å drepe uönskede målceller |
US5747349A (en) * | 1996-03-20 | 1998-05-05 | University Of Washington | Fluorescent reporter beads for fluid analysis |
US7041510B2 (en) | 1996-04-25 | 2006-05-09 | Bioarray Solutions Ltd. | System and method for programmable illumination pattern generation |
US6387707B1 (en) * | 1996-04-25 | 2002-05-14 | Bioarray Solutions | Array Cytometry |
US6958245B2 (en) | 1996-04-25 | 2005-10-25 | Bioarray Solutions Ltd. | Array cytometry |
US6251691B1 (en) * | 1996-04-25 | 2001-06-26 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
US7144119B2 (en) * | 1996-04-25 | 2006-12-05 | Bioarray Solutions Ltd. | System and method for programmable illumination pattern generation |
US6449562B1 (en) | 1996-10-10 | 2002-09-10 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
DK0849595T3 (da) * | 1996-12-18 | 2001-05-28 | Diagnostische Forsch Stiftung | Syntetiske partikler som agglutinationsreagenser |
NO308755B1 (no) * | 1996-12-20 | 2000-10-23 | Iystein Fodstad | FremgangsmÕte til karakterisering av unormale celler, anvendelse og sett for utførelse av fremgangsmÕten |
US20030027126A1 (en) | 1997-03-14 | 2003-02-06 | Walt David R. | Methods for detecting target analytes and enzymatic reactions |
US7622294B2 (en) * | 1997-03-14 | 2009-11-24 | Trustees Of Tufts College | Methods for detecting target analytes and enzymatic reactions |
AU756945B2 (en) | 1997-05-23 | 2003-01-30 | Bioarray Solutions Ltd | Color-encoding and in-situ interrogation of matrix-coupled chemical compounds |
US6908770B1 (en) | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
US7018846B1 (en) | 1998-08-10 | 2006-03-28 | Science & Technology Corporation @ Unm | Display of receptors and analysis of binding interactions and drug libraries |
US7189519B2 (en) * | 1998-08-10 | 2007-03-13 | Stc.Unm | Bead-based detection of ligand-GPCR-G protein complexes |
CA2254223A1 (en) * | 1998-11-16 | 2000-05-16 | Biophys, Inc. | Device and method for analyzing a biologic sample |
US7297554B2 (en) * | 1998-11-18 | 2007-11-20 | Microdiagnostics, Inc. | Immunoassay system |
US6815172B1 (en) | 1999-06-11 | 2004-11-09 | The United States Of America As Represented By The Department Of Health And Human Services | Methods and compositions for opsonophagocytic assays |
US6589779B1 (en) | 1999-07-16 | 2003-07-08 | Board Of Regents, The University Of Texas System | General signaling protocol for chemical receptors in immobilized matrices |
US7022517B1 (en) | 1999-07-16 | 2006-04-04 | Board Of Regents, The University Of Texas System | Method and apparatus for the delivery of samples to a chemical sensor array |
DE60135092D1 (de) | 2000-01-31 | 2008-09-11 | Univ Texas | Tragbare vorrichtung mit einer sensor-array-anordnung |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
EP1311839B1 (de) | 2000-06-21 | 2006-03-01 | Bioarray Solutions Ltd | Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays |
US7057704B2 (en) * | 2000-09-17 | 2006-06-06 | Bioarray Solutions Ltd. | System and method for programmable illumination pattern generation |
US20030045005A1 (en) * | 2000-10-17 | 2003-03-06 | Michael Seul | Light-controlled electrokinetic assembly of particles near surfaces |
US7691645B2 (en) * | 2001-01-09 | 2010-04-06 | Agilent Technologies, Inc. | Immunosubtraction method |
EP1373874A4 (de) * | 2001-01-31 | 2004-03-31 | Univ Texas | Verfahren und vorrichtung zum eingrenzen von materialien in einem mikrobearbeiteten chemischen sensorarray |
AU2002255515A1 (en) * | 2001-02-05 | 2002-08-19 | Board Of Regents, The University Of Texas System | The use of mesoscale self-assembly and recognition to effect delivery of sensing reagent for arrayed sensors |
US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
US20040002073A1 (en) | 2001-10-15 | 2004-01-01 | Li Alice Xiang | Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection |
US6838289B2 (en) * | 2001-11-14 | 2005-01-04 | Beckman Coulter, Inc. | Analyte detection system |
US7241629B2 (en) | 2001-12-20 | 2007-07-10 | Corning Incorporated | Detectable labels, methods of manufacture and use |
US20040171076A1 (en) * | 2001-12-20 | 2004-09-02 | Dejneka Matthew J. | Detectable micro to nano sized structures, methods of manufacture and use |
AU2003228711C1 (en) | 2002-04-26 | 2010-01-07 | Board Of Regents, The University Of Texas System | Method and system for the detection of cardiac risk factors |
DE60308259T2 (de) * | 2002-05-22 | 2007-04-05 | Sysmex Corp. | Immunologische Verfahren, Vorrichtungen und Reagenzien |
US7526114B2 (en) | 2002-11-15 | 2009-04-28 | Bioarray Solutions Ltd. | Analysis, secure access to, and transmission of array images |
US7232659B1 (en) | 2003-02-04 | 2007-06-19 | Stc.Unm | Multiplex analysis for high throughput discrimination of GPCR agonists and antagonists |
US20050064452A1 (en) * | 2003-04-25 | 2005-03-24 | Schmid Matthew J. | System and method for the detection of analytes |
US9317922B2 (en) | 2003-05-16 | 2016-04-19 | Board Of Regents The University Of Texas System | Image and part recognition technology |
US7651850B2 (en) * | 2003-05-16 | 2010-01-26 | Board Of Regents, The University Of Texas System | Image and part recognition technology |
CA2531105C (en) * | 2003-07-05 | 2015-03-17 | The Johns Hopkins University | Method and compositions for detection and enumeration of genetic variations |
US7927796B2 (en) | 2003-09-18 | 2011-04-19 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
WO2005031305A2 (en) | 2003-09-22 | 2005-04-07 | Bioarray Solutions, Ltd. | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules |
US20050079484A1 (en) * | 2003-10-10 | 2005-04-14 | Heineman William Richard | Method of detecting biological materials in liquid |
US7563569B2 (en) | 2003-10-28 | 2009-07-21 | Michael Seul | Optimization of gene expression analysis using immobilized capture probes |
JP2007509629A (ja) | 2003-10-29 | 2007-04-19 | バイオアレイ ソリューションズ リミテッド | 二本鎖dnaの切断による複合核酸分析 |
US7651868B2 (en) * | 2003-12-11 | 2010-01-26 | The Board Of Regents Of The University Of Texas System | Method and system for the analysis of saliva using a sensor array |
US8101431B2 (en) | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
US8105849B2 (en) | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
US8377398B2 (en) | 2005-05-31 | 2013-02-19 | The Board Of Regents Of The University Of Texas System | Methods and compositions related to determination and use of white blood cell counts |
US8486629B2 (en) | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
CA2613078A1 (en) * | 2005-06-24 | 2007-01-04 | Board Of Regents, The University Of Texas System | Systems and methods including self-contained cartridges with detection systems and fluid delivery systems |
US20070043510A1 (en) * | 2005-08-19 | 2007-02-22 | Beckman Coulter, Inc. | Assay system |
US7572990B2 (en) * | 2007-03-30 | 2009-08-11 | Intermec Ip Corp. | Keypad overlay membrane |
JP6277099B2 (ja) * | 2014-09-09 | 2018-02-07 | 富士フイルム株式会社 | 試薬キット、測定キット及び被検物質の測定方法。 |
WO2020249724A1 (en) | 2019-06-13 | 2020-12-17 | Fundació Hospital Universitari Vall D'hebron - Institut De Recerca | Synthrocyte: erythrocyte-mimicking reagent and fast methods for pathogen characterization and serology testing |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2123146B (en) * | 1982-06-28 | 1985-09-25 | Abbott Lab | Dual parameter flow immunoassays |
US4564598A (en) * | 1982-07-12 | 1986-01-14 | Syntex (U.S.A.) Inc. | Limited volume method for particle counting |
US4717655A (en) * | 1982-08-30 | 1988-01-05 | Becton, Dickinson And Company | Method and apparatus for distinguishing multiple subpopulations of cells |
US4499052A (en) * | 1982-08-30 | 1985-02-12 | Becton, Dickinson And Company | Apparatus for distinguishing multiple subpopulations of cells |
US4550017A (en) * | 1982-10-15 | 1985-10-29 | Syntex (U.S.A.) Inc. | Fluorescence screening for blood typing |
DE3322373C2 (de) * | 1983-05-19 | 1986-12-04 | Ioannis Dr. 3000 Hannover Tripatzis | Testmittel und Verfahren zum Nachweis von Antigenen und/oder Antikörpern |
US4745075A (en) * | 1984-09-06 | 1988-05-17 | Burroughs Wellcome Co. | Diagnostic test methods |
JPS61128169A (ja) * | 1984-11-27 | 1986-06-16 | Mitsubishi Chem Ind Ltd | 免疫分析法 |
US4918004A (en) * | 1984-12-24 | 1990-04-17 | Caribbean Microparticles Corporation | Method of calibrating a flow cytometer or fluorescence microscope for quantitating binding antibodies on a selected sample, and microbead calibration kit therefor |
CA1291031C (en) * | 1985-12-23 | 1991-10-22 | Nikolaas C.J. De Jaeger | Method for the detection of specific binding agents and their correspondingbindable substances |
JPH07104349B2 (ja) * | 1987-04-11 | 1995-11-13 | 株式会社日立製作所 | 細胞測定法 |
US4829011A (en) * | 1987-08-27 | 1989-05-09 | Biotrack, Inc. | Agglutination assay |
FR2627286B1 (fr) * | 1988-02-15 | 1993-08-20 | Canon Kk | Procede et appareil pour l'examen d'un echantillon en immunologie |
US4934811A (en) * | 1988-04-01 | 1990-06-19 | Syntex (U.S.A.) Inc. | Apparatus and method for detection of fluorescence or light scatter |
US5047321A (en) * | 1988-06-15 | 1991-09-10 | Becton Dickinson & Co. | Method for analysis of cellular components of a fluid |
-
1988
- 1988-11-04 FR FR8814420A patent/FR2638848B1/fr not_active Expired - Fee Related
-
1989
- 1989-11-03 WO PCT/FR1989/000573 patent/WO1990005307A1/fr active IP Right Grant
- 1989-11-03 AU AU45186/89A patent/AU4518689A/en not_active Abandoned
- 1989-11-03 DE DE68922844T patent/DE68922844T2/de not_active Expired - Fee Related
- 1989-11-03 JP JP1511669A patent/JPH03502246A/ja active Pending
- 1989-11-03 EP EP89912640A patent/EP0397828B1/de not_active Expired - Lifetime
- 1989-11-03 US US07/499,509 patent/US5219763A/en not_active Expired - Fee Related
- 1989-11-03 AT AT89912640T patent/ATE123150T1/de not_active IP Right Cessation
-
1993
- 1993-02-25 US US08/022,321 patent/US5405784A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE68922844T2 (de) | 1995-12-21 |
EP0397828B1 (de) | 1995-05-24 |
WO1990005307A1 (fr) | 1990-05-17 |
FR2638848B1 (fr) | 1993-01-22 |
ATE123150T1 (de) | 1995-06-15 |
US5219763A (en) | 1993-06-15 |
JPH03502246A (ja) | 1991-05-23 |
AU4518689A (en) | 1990-05-28 |
EP0397828A1 (de) | 1990-11-22 |
US5405784A (en) | 1995-04-11 |
FR2638848A1 (fr) | 1990-05-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE68922844D1 (de) | Agglutinationsverfahren zur Bestimmung von mehreren Liganden. | |
DE68920176D1 (de) | Festphasenanalytische Vorrichtung und Verfahren zum Gebrauch derselben. | |
ATE452206T1 (de) | Verfahren für verbesserte lumineszenztests unter verwendung von mikropartikeln | |
ATE187820T1 (de) | Verfahren zur analyse partikelverstärkter agglutinationsreaktionen auf zentrifugalanalysatoren durch bestimmung der trübungsaufhellung | |
ATE87743T1 (de) | Verfahren zum nachweis von spezifischen bindemitteln und ihren korrespondierenden bindbaren stoffen. | |
NO900534L (no) | Bestemmelse av omgivelseskonsentrasjonen i flere analytter | |
ATE241139T1 (de) | Vorrichtung zur durchführung eines oder mehrerer kompetitiver immunoassays | |
ATE57577T1 (de) | Immunoassay-methoden unter anwendung von mustern fuer die auffindung von loeslichen antigenen und zelloberflaechenantigenen. | |
DE69227379D1 (de) | Verfahren und Reagenzien zur Bestimmung von Bakterien in der zerebrospinalen Flüssigkeit | |
DE69333289D1 (de) | Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien | |
ATE133257T1 (de) | Ermittlung und quantifizierung mehrerer analyten unter verwendung von markierungstechniken | |
ATE65092T1 (de) | Verstaerkung von hybridisierungssignalen durch verwendung von komplementarischen dns-straengen. | |
ATE12010T1 (de) | Verfahren zur bestimmung von antigen-antikoerper- reaktionen und reagens hierfuer. | |
ATE524737T1 (de) | Verfahren und vorrichtung zur bestimmung mehrerer analyten mit simultaner internen kontrolle in einer grafischen kombination | |
DE3650437D1 (de) | Verfahren zum Messen von Freiliganden in biologischen Flüssigkeiten. | |
CA2021658A1 (en) | Multiplex immunoassay system | |
MY106963A (en) | Agglutination assay. | |
ATE114050T1 (de) | Verfahren zur quantitativen und qualitativen bestimmung von antikörpern gegen bakterielle antigene mittels photometrischer messung der agglutination. | |
CA2051618A1 (en) | Immunoassay for pyridostigmine | |
DE69016265T2 (de) | Verfahren zur Bestimmung von Isoenzymen. | |
ATE119670T1 (de) | Nichtspezifische adsorptionsfreie methode zur bestimmung eines antikörpers und bestimmungsreagentien. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |