DE68928422D1 - Die Diagnose, die Bewertung und die Behandlung von einer Krankheit der Kranzarterie durch die Übungssimulierung unter Verwendung von einer geschlossenen Kreislauf Arzneimittellieferung eines übungssimulierenden Beta-Agonisten - Google Patents

Die Diagnose, die Bewertung und die Behandlung von einer Krankheit der Kranzarterie durch die Übungssimulierung unter Verwendung von einer geschlossenen Kreislauf Arzneimittellieferung eines übungssimulierenden Beta-Agonisten

Info

Publication number
DE68928422D1
DE68928422D1 DE68928422T DE68928422T DE68928422D1 DE 68928422 D1 DE68928422 D1 DE 68928422D1 DE 68928422 T DE68928422 T DE 68928422T DE 68928422 T DE68928422 T DE 68928422T DE 68928422 D1 DE68928422 D1 DE 68928422D1
Authority
DE
Germany
Prior art keywords
exercise
responses
drug delivery
coronary artery
artery disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68928422T
Other languages
English (en)
Other versions
DE68928422T2 (de
Inventor
Ronald Ralph Tuttle
Iii Clinton Eugene Brow Browne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sicor Inc
Original Assignee
Sicor Inc
Gensia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicor Inc, Gensia Inc filed Critical Sicor Inc
Application granted granted Critical
Publication of DE68928422D1 publication Critical patent/DE68928422D1/de
Publication of DE68928422T2 publication Critical patent/DE68928422T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
    • C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/13—Infusion monitoring
DE68928422T 1988-02-19 1989-02-17 Die Diagnose, die Bewertung und die Behandlung von einer Krankheit der Kranzarterie durch die Übungssimulierung unter Verwendung von einer geschlossenen Kreislauf Arzneimittellieferung eines übungssimulierenden Beta-Agonisten Expired - Fee Related DE68928422T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15787588A 1988-02-19 1988-02-19
US07/308,683 US5108363A (en) 1988-02-19 1989-02-09 Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist

Publications (2)

Publication Number Publication Date
DE68928422D1 true DE68928422D1 (de) 1997-12-04
DE68928422T2 DE68928422T2 (de) 1998-02-26

Family

ID=26854551

Family Applications (2)

Application Number Title Priority Date Filing Date
DE68928422T Expired - Fee Related DE68928422T2 (de) 1988-02-19 1989-02-17 Die Diagnose, die Bewertung und die Behandlung von einer Krankheit der Kranzarterie durch die Übungssimulierung unter Verwendung von einer geschlossenen Kreislauf Arzneimittellieferung eines übungssimulierenden Beta-Agonisten
DE68924661T Expired - Fee Related DE68924661T2 (de) 1988-02-19 1989-02-17 System zur Verabreichung von einem, eine Übung simulierenden Medikaments im geschlossenen Kreislauf.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE68924661T Expired - Fee Related DE68924661T2 (de) 1988-02-19 1989-02-17 System zur Verabreichung von einem, eine Übung simulierenden Medikaments im geschlossenen Kreislauf.

Country Status (13)

Country Link
US (4) US5108363A (de)
EP (2) EP0658538B1 (de)
JP (2) JP2806543B2 (de)
AT (2) ATE159710T1 (de)
AU (1) AU634152B2 (de)
DE (2) DE68928422T2 (de)
DK (1) DK73589A (de)
ES (2) ES2081299T3 (de)
FI (1) FI890776A (de)
GR (2) GR3018764T3 (de)
IE (2) IE80716B1 (de)
NO (1) NO890704L (de)
NZ (1) NZ239270A (de)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6144385A (ja) * 1984-08-07 1986-03-04 Tokyu Constr Co Ltd 構造物内の放射線吸収体の探査方法
IL82997A0 (en) * 1986-07-11 1987-12-20 Tanabe Seiyaku Co Method for epimerizing an optically active benzyl alcohol derivative
US5108363A (en) * 1988-02-19 1992-04-28 Gensia Pharmaceuticals, Inc. Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist
JPH03133946A (ja) * 1989-10-10 1991-06-07 Glaxo Group Ltd フェンエタノールアミン化合物
US5023085A (en) * 1989-11-29 1991-06-11 Pfizer Inc. Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals
US5254087A (en) * 1990-01-29 1993-10-19 Ivra Systems, Inc. Tourniquet apparatus for intravenous regional anesthesia
US5556415A (en) * 1990-01-29 1996-09-17 Mcewen; James A. Physiologic tourniquet for intravenous regional anesthesia
US5607447A (en) * 1993-09-28 1997-03-04 Mcewen; James A. Physiologic tourniquet
US5281623A (en) * 1990-08-27 1994-01-25 Eli Lilly And Company Method for treating inflammation
WO1993009779A1 (en) * 1991-11-13 1993-05-27 Gensia, Inc. Methods for increasing the sensitivity and decreasing the side effects of pharmacological stress testing for coronary artery disease
IL104365A0 (en) * 1992-01-31 1993-05-13 Gensia Pharma Method and apparatus for closed loop drug delivery
HUT64459A (en) * 1992-03-31 1994-01-28 Richter Gedeon Vegyeszet Process and apparatus for the diagnostics of cardiovascular
US5752521A (en) 1993-11-12 1998-05-19 Dardik; Irving I. Therapeutic exercise program
US6397098B1 (en) * 1994-09-21 2002-05-28 Medrad, Inc. Data communication and control for medical imaging systems
US5840026A (en) * 1994-09-21 1998-11-24 Medrad, Inc. Patient specific dosing contrast delivery systems and methods
US5551953A (en) * 1994-10-31 1996-09-03 Alza Corporation Electrotransport system with remote telemetry link
US7204848B1 (en) 1995-03-01 2007-04-17 Boston Scientific Scimed, Inc. Longitudinally flexible expandable stent
US5775329A (en) * 1995-06-07 1998-07-07 Gensia, Inc. Method and compounds for diagnosing coronary artery disease
US5855589A (en) * 1995-08-25 1999-01-05 Mcewen; James A. Physiologic tourniquet for intravenous regional anesthesia
US5931853A (en) * 1995-08-25 1999-08-03 Mcewen; James A. Physiologic tourniquet with safety circuit
US6430997B1 (en) 1995-11-06 2002-08-13 Trazer Technologies, Inc. System and method for tracking and assessing movement skills in multidimensional space
DE69614146T2 (de) * 1995-12-22 2002-04-11 Abbott Lab Verfahren zur herstellung von alkyl oder aryl aldehydzwischenprodukten
US5874601A (en) * 1996-03-14 1999-02-23 Abbott Laboratories Process of protecting a 1,2-aminoalcohol for reductive amination coupling
US5706822A (en) * 1996-03-29 1998-01-13 Kozz Incorporated Method and computer program for creating individualized exercise protocols
US5735814A (en) * 1996-04-30 1998-04-07 Medtronic, Inc. Techniques of treating neurodegenerative disorders by brain infusion
US5711316A (en) * 1996-04-30 1998-01-27 Medtronic, Inc. Method of treating movement disorders by brain infusion
US5713923A (en) * 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion
DE69730737D1 (de) * 1996-12-02 2004-10-21 Chisso Corp Optisch aktive nitroalkohol-derivate, optisch aktive aminoalkohol-derivate und verfahren zu ihrer herstellung
US6018679A (en) * 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
AU750050B2 (en) * 1998-06-03 2002-07-11 Scott Laboratories, Inc. Apparatus and method for providing a conscious patient relief from pain and anxiety associated with medical or surgical procedures
US6302874B1 (en) * 1998-07-13 2001-10-16 Genetronics, Inc. Method and apparatus for electrically assisted topical delivery of agents for cosmetic applications
US20030166550A1 (en) * 1999-08-27 2003-09-04 Chiron Corporation Angiogenically effective unit dose of FGF-2 and method of use
AU6411199A (en) * 1998-10-13 2000-05-01 Chiron Corporation Angiogenically effective unit dose of fgf and method of administering
US6440934B1 (en) 1998-10-13 2002-08-27 Chiron Corporation Angiogenically effective unit dose of FGF-2 and method of use
US20020072489A1 (en) * 1998-10-13 2002-06-13 Whitehouse Martha J. Angiogenically effective unit dose of FGF-2 and method of use
US6475514B1 (en) * 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
US6361522B1 (en) * 1999-10-21 2002-03-26 Cardiac Pacemakers, Inc. Drug delivery system for implantable cardiac device
US7860583B2 (en) 2004-08-25 2010-12-28 Carefusion 303, Inc. System and method for dynamically adjusting patient therapy
US11087873B2 (en) 2000-05-18 2021-08-10 Carefusion 303, Inc. Context-aware healthcare notification system
NZ522631A (en) 2000-05-18 2004-07-30 Alaris Medical Inc Distributed remote asset and medication management drug delivery system
US9069887B2 (en) * 2000-05-18 2015-06-30 Carefusion 303, Inc. Patient-specific medication management system
US10062457B2 (en) 2012-07-26 2018-08-28 Carefusion 303, Inc. Predictive notifications for adverse patient events
US9741001B2 (en) 2000-05-18 2017-08-22 Carefusion 303, Inc. Predictive medication safety
US10353856B2 (en) 2011-03-17 2019-07-16 Carefusion 303, Inc. Scalable communication system
US9427520B2 (en) 2005-02-11 2016-08-30 Carefusion 303, Inc. Management of pending medication orders
WO2002003076A2 (en) 2000-06-30 2002-01-10 Lifewaves International, Inc. Systems and methods for assessing and modifying an individual's physiological condition
US7369890B2 (en) 2000-11-02 2008-05-06 Cardiac Pacemakers, Inc. Technique for discriminating between coordinated and uncoordinated cardiac rhythms
US6689117B2 (en) 2000-12-18 2004-02-10 Cardiac Pacemakers, Inc. Drug delivery system for implantable medical device
US7209783B2 (en) * 2001-06-15 2007-04-24 Cardiac Pacemakers, Inc. Ablation stent for treating atrial fibrillation
US7493162B2 (en) * 2001-06-15 2009-02-17 Cardiac Pacemakers, Inc. Pulmonary vein stent for treating atrial fibrillation
US7340303B2 (en) 2001-09-25 2008-03-04 Cardiac Pacemakers, Inc. Evoked response sensing for ischemia detection
MXPA04004246A (es) * 2001-11-01 2004-09-10 Scott Lab Inc Interfaz de usuario para sistemas y metodos de suministro de sedacion y analgesia.
US8775196B2 (en) 2002-01-29 2014-07-08 Baxter International Inc. System and method for notification and escalation of medical data
US10173008B2 (en) 2002-01-29 2019-01-08 Baxter International Inc. System and method for communicating with a dialysis machine through a network
US20030140928A1 (en) * 2002-01-29 2003-07-31 Tuan Bui Medical treatment verification system and method
US7236821B2 (en) * 2002-02-19 2007-06-26 Cardiac Pacemakers, Inc. Chronically-implanted device for sensing and therapy
EP1494685B1 (de) * 2002-04-18 2008-12-31 Cv Therapeutics, Inc. Methode zur behandlung von herzrhythmusstörungen mit einem a1 adenosin agonist zusammen mit einem beta blocker
US20040172301A1 (en) * 2002-04-30 2004-09-02 Mihai Dan M. Remote multi-purpose user interface for a healthcare system
US20040172300A1 (en) * 2002-04-30 2004-09-02 Mihai Dan M. Method and system for integrating data flows
US20040167804A1 (en) * 2002-04-30 2004-08-26 Simpson Thomas L.C. Medical data communication notification and messaging system and method
US8234128B2 (en) 2002-04-30 2012-07-31 Baxter International, Inc. System and method for verifying medical device operational parameters
US20040176667A1 (en) * 2002-04-30 2004-09-09 Mihai Dan M. Method and system for medical device connectivity
US20050065817A1 (en) * 2002-04-30 2005-03-24 Mihai Dan M. Separation of validated information and functions in a healthcare system
ES2304521T3 (es) * 2002-06-20 2008-10-16 The Governors Of The University Of Alberta Dicloroacetato en combinacion con farmacos cardioprotectores o hemodinamicos.
US7089055B2 (en) * 2002-06-28 2006-08-08 Cardiac Pacemakers, Inc. Method and apparatus for delivering pre-shock defibrillation therapy
CN101828904A (zh) 2002-10-03 2010-09-15 斯科特实验室公司 用于提供传感器融合的系统和方法
AU2003275460A1 (en) * 2002-10-03 2004-04-23 Scott Laboratories, Inc. Systems and methods for providing trend analysis in a sedation and analgesia system
US7072711B2 (en) 2002-11-12 2006-07-04 Cardiac Pacemakers, Inc. Implantable device for delivering cardiac drug therapy
US7627373B2 (en) 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
US20050026884A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20090285900A1 (en) * 2003-07-31 2009-11-19 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20050113318A1 (en) * 2003-07-31 2005-05-26 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US7320675B2 (en) 2003-08-21 2008-01-22 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure
GB0403864D0 (en) * 2004-02-20 2004-03-24 Ucl Ventures Modulator
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7567841B2 (en) 2004-08-20 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for delivering combined electrical and drug therapies
WO2006055813A2 (en) 2004-11-16 2006-05-26 Medrad, Inc. Modeling of pharmaceutical propagation
EP2990073B1 (de) * 2004-11-24 2018-05-02 Bayer Healthcare LLC Vorrichtungen und systeme zur flüssigkeitsabgabe
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
US8182443B1 (en) * 2006-01-17 2012-05-22 Masimo Corporation Drug administration controller
WO2007087505A2 (en) * 2006-01-25 2007-08-02 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
WO2008085421A2 (en) 2006-12-29 2008-07-17 Medrad, Inc. Patient-based parameter generation systems for medical injection procedures
EP2117524B8 (de) * 2007-01-29 2019-09-25 National Research Council of Canada Verwendung von catecholaminen und entsprechenden verbindungen als mittel gegen angiogenese
CN103976736B (zh) 2007-07-17 2017-01-11 拜耳医药保健有限责任公司 确定心肺功能评估和输液过程的参数的设备和系统
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
US10089443B2 (en) 2012-05-15 2018-10-02 Baxter International Inc. Home medical device systems and methods for therapy prescription and tracking, servicing and inventory
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
EP2334234A4 (de) 2008-09-19 2013-03-20 Tandem Diabetes Care Inc Vorrichtung zur messung der konzentration eines gelösten stoffs und entsprechende verfahren
US8554579B2 (en) 2008-10-13 2013-10-08 Fht, Inc. Management, reporting and benchmarking of medication preparation
US9421330B2 (en) * 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
WO2011014704A2 (en) 2009-07-30 2011-02-03 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
US20110137297A1 (en) * 2009-09-17 2011-06-09 Kiani Massi Joe E Pharmacological management system
CA2803169C (en) 2010-06-24 2020-09-22 Medrad, Inc. Modeling of pharmaceutical propagation and parameter generation for injection protocols
HUE056182T2 (hu) 2012-05-14 2022-01-28 Bayer Healthcare Llc Összeállítások és eljárások gyógyászati fluidum befecskendezési protokollok röntgencsõ-feszültség alapján történõ meghatározására
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US8761717B1 (en) 2012-08-07 2014-06-24 Brian K. Buchheit Safety feature to disable an electronic device when a wireless implantable medical device (IMD) is proximate
US10552577B2 (en) 2012-08-31 2020-02-04 Baxter Corporation Englewood Medication requisition fulfillment system and method
SG11201503190RA (en) 2012-10-26 2015-05-28 Baxter Corp Englewood Improved image acquisition for medical dose preparation system
EP2911641B1 (de) 2012-10-26 2018-10-17 Baxter Corporation Englewood Verbesserte arbeitsstation für medizinische dosiszubereitung
US11182728B2 (en) 2013-01-30 2021-11-23 Carefusion 303, Inc. Medication workflow management
US10430554B2 (en) 2013-05-23 2019-10-01 Carefusion 303, Inc. Medication preparation queue
US9946844B2 (en) * 2013-02-22 2018-04-17 Cloud Dx, Inc. Systems and methods for monitoring patient medication adherence
WO2014164565A1 (en) 2013-03-13 2014-10-09 Carefusion 303, Inc. Predictive medication safety
US9555379B2 (en) 2013-03-13 2017-01-31 Bayer Healthcare Llc Fluid path set with turbulent mixing chamber, backflow compensator
WO2014159280A1 (en) 2013-03-13 2014-10-02 Carefusion 303, Inc. Patient-specific medication management system
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
EP3161778A4 (de) 2014-06-30 2018-03-14 Baxter Corporation Englewood Verwalteter austausch medizinischer informationen
US11575673B2 (en) 2014-09-30 2023-02-07 Baxter Corporation Englewood Central user management in a distributed healthcare information management system
US11107574B2 (en) 2014-09-30 2021-08-31 Baxter Corporation Englewood Management of medication preparation with formulary management
WO2016090091A1 (en) 2014-12-05 2016-06-09 Baxter Corporation Englewood Dose preparation data analytics
EP3265989A4 (de) 2015-03-03 2018-10-24 Baxter Corporation Englewood Pharmaziearbeitsflussverwaltung mit integrierten alarmen
CA2985719C (en) 2015-06-25 2024-03-26 Gambro Lundia Ab Medical device system and method having a distributed database
WO2017152036A1 (en) 2016-03-03 2017-09-08 Bayer Healthcare Llc System and method for improved fluid delivery in multi-fluid injector systems
WO2018114346A1 (en) 2016-12-21 2018-06-28 Gambro Lundia Ab Medical device system including information technology infrastructure having secure cluster domain supporting external domain
EP3675930B1 (de) 2017-08-31 2024-01-17 Bayer Healthcare LLC Verfahren zur mechanischen kalibrierung der antriebselementposition und eines fluidinjektorsystems
AU2018326485B2 (en) 2017-08-31 2024-01-04 Bayer Healthcare Llc Injector pressure calibration system and method
CN110809482B (zh) 2017-08-31 2023-03-07 拜耳医药保健有限公司 流体注入器系统体积补偿系统和方法
US11779702B2 (en) 2017-08-31 2023-10-10 Bayer Healthcare Llc Method for dynamic pressure control in a fluid injector system
US11141535B2 (en) 2017-08-31 2021-10-12 Bayer Healthcare Llc Fluid path impedance assessment for improving fluid delivery performance
US11654236B2 (en) 2019-11-22 2023-05-23 Tandem Diabetes Care, Inc. Systems and methods for automated insulin delivery for diabetes therapy
US11911595B2 (en) 2020-05-18 2024-02-27 Tandem Diabetes Care, Inc. Systems and methods for automated insulin delivery response to meal announcements

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA570892A (en) * 1959-02-17 D. Moed Hendrik Method of producing substituted aralkyl-, phenyl-, alkylamines
DE1144291B (de) * 1957-11-05 1963-02-28 Philips Nv Verfahren zur Herstellung einer optisch-aktiven broncholytisch wirksamen Verbindung
US3135797A (en) * 1958-04-15 1964-06-02 Colgate Palmolive Co Aromatic amino antispasmodic compounds
US3319623A (en) * 1964-07-13 1967-05-16 Seymour B London Blood pressure monitors
US3969410A (en) * 1972-01-12 1976-07-13 Boehringer Ingelheim Gmbh 1-(2'-Alkyl-3',4'-dihydroxy-phenyl)-2-(phenylalkyl-amino)-alkanols-(1) and salts thereof
US3803320A (en) * 1968-07-24 1974-04-09 Geigy Chem Corp Control of insects,acarinae and nematodes with basically substituted 1-cyano-o-carbamoyl-formoximes
US3803230A (en) * 1969-05-30 1974-04-09 Allen & Hanburys Ltd 5-(2-((1-methyl-3-phenylpropyl)amino)ethyl)salicylamide hydrochloride
US3651806A (en) * 1969-10-24 1972-03-28 Philip I Hirshberg Method and apparatus for administering digitalizing medications
GB1301134A (en) * 1970-07-18 1972-12-29 Pfizer Ltd SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
NL7112938A (de) * 1970-09-30 1972-04-05
US3987200A (en) * 1972-04-12 1976-10-19 Eli Lilly And Company Method for increasing cardiac contractility
JPS5310582B2 (de) * 1973-04-28 1978-04-14
FR2328456A1 (fr) * 1975-10-22 1977-05-20 Bruneau & Cie Lab Derives de phenylethanolamine, leur preparation et leur application en therapeutique
US4080966A (en) * 1976-08-12 1978-03-28 Trustees Of The University Of Pennsylvania Automated infusion apparatus for blood pressure control and method
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4078562A (en) * 1976-08-16 1978-03-14 Diana W. Friedman Infusion pump with feedback control
SE402569B (sv) * 1976-11-09 1978-07-10 Aga Ab Anordning vid en andningsapparat for dykare
FI791727A (fi) * 1978-06-05 1979-12-06 Ciba Geigy Ag Foerfarande foer framstaellning av n-alkylerade aminoalkoholer
EP0006735B1 (de) * 1978-06-28 1983-06-15 Beecham Group Plc Sekundäre Amine, ihre Herstellung, pharmazeutische Zusammensetzungen, die sie enthalten, und deren Verwendung
DK269079A (da) * 1978-07-03 1980-02-01 Lilly Co Eli Fremgangsmaade til fremstilling af phenethanolaminer
US4845127A (en) * 1978-07-03 1989-07-04 Eli Lilly And Company Phenethanolamines, compositions containing the same and method for effecting weight control
DE3061205D1 (en) * 1979-06-16 1983-01-05 Beecham Group Plc Secondary amines, their preparation and use in pharmaceutical compositions
US4280494A (en) * 1979-06-26 1981-07-28 Cosgrove Robert J Jun System for automatic feedback-controlled administration of drugs
US4392849A (en) * 1981-07-27 1983-07-12 The Cleveland Clinic Foundation Infusion pump controller
CA1247451A (en) * 1983-01-31 1988-12-28 David B. Anderson Phenethanolamines
US4837305A (en) * 1983-02-03 1989-06-06 The Regents Of The University Of California Derivatives of β-adrenergic antagonists
US5135479A (en) * 1983-08-18 1992-08-04 Drug Delivery Systems, Inc. Programmable control and mounting system for transdermal drug applicator
WO1986007269A1 (en) * 1985-06-10 1986-12-18 Drug Delivery Systems Inc. Programmable control and mounting system for transdermal drug applicator
EP0135905A3 (de) * 1983-09-29 1986-10-22 ASTA Pharma Aktiengesellschaft Neue 1-(Alkyl-hydroxy-phenyl)-1-hydroxy-2-(alkylamino)-propane
US4562206A (en) * 1983-12-23 1985-12-31 Key Pharmaceuticals, Inc. Orally effective inotropic compounds
US4865584A (en) * 1984-02-08 1989-09-12 Omni-Flow, Inc. Cassette for programable multiple input infusion system
CA1254091A (en) * 1984-09-28 1989-05-16 Vladimir Feingold Implantable medication infusion system
US5088981A (en) * 1985-01-18 1992-02-18 Howson David C Safety enhanced device and method for effecting application of a therapeutic agent
US4688577A (en) * 1986-02-10 1987-08-25 Bro William J Apparatus for and method of monitoring and controlling body-function parameters during intracranial observation
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4931046A (en) * 1987-05-15 1990-06-05 Newman Martin H Iontophoresis drug delivery system
EP0313638A4 (de) * 1987-05-15 1989-06-14 Martin H Newman Arzneimittelverabreichungssystem durch inophorese.
US5108363A (en) * 1988-02-19 1992-04-28 Gensia Pharmaceuticals, Inc. Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist
US4846792A (en) * 1988-03-08 1989-07-11 Baxter International Inc. Automatic infiltration detection system and method

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IE80716B1 (en) 1998-12-30
US5395970A (en) 1995-03-07
EP0658538B1 (de) 1997-10-29
JP2806543B2 (ja) 1998-09-30
ATE129644T1 (de) 1995-11-15
NZ239270A (en) 1993-10-26
DE68928422T2 (de) 1998-02-26
GR3018764T3 (en) 1996-04-30
DE68924661T2 (de) 1996-03-21
ES2111973T3 (es) 1998-03-16
GR3025892T3 (en) 1998-04-30
AU3008889A (en) 1989-08-24
ES2081299T3 (es) 1996-03-01
DK73589A (da) 1989-08-20
US5286252A (en) 1994-02-15
EP0329464A3 (de) 1991-07-17
NO890704D0 (no) 1989-02-20
JPH10276991A (ja) 1998-10-20
AU634152B2 (en) 1993-02-18
EP0329464B1 (de) 1995-11-02
NO890704L (no) 1989-08-21
IE71651B1 (en) 1997-02-26
ATE159710T1 (de) 1997-11-15
FI890776A (fi) 1989-08-20
EP0658538A1 (de) 1995-06-21
DE68924661D1 (de) 1995-12-07
EP0329464A2 (de) 1989-08-23
FI890776A0 (fi) 1989-02-17
US5460605A (en) 1995-10-24
JPH0217048A (ja) 1990-01-22
IE960742L (en) 1989-08-19
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DK73589D0 (da) 1989-02-17
US5108363A (en) 1992-04-28

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