DE69010001D1 - Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika. - Google Patents

Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.

Info

Publication number
DE69010001D1
DE69010001D1 DE69010001T DE69010001T DE69010001D1 DE 69010001 D1 DE69010001 D1 DE 69010001D1 DE 69010001 T DE69010001 T DE 69010001T DE 69010001 T DE69010001 T DE 69010001T DE 69010001 D1 DE69010001 D1 DE 69010001D1
Authority
DE
Germany
Prior art keywords
amino acid
aeruginosa
piline
diagnostics
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69010001T
Other languages
English (en)
Other versions
DE69010001T2 (de
Inventor
Robert Hodges
William Paranchych
Kok Lee
Sastry Parami
Randall Irvin
Peter Doig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Alberta
Original Assignee
University of Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Alberta filed Critical University of Alberta
Publication of DE69010001D1 publication Critical patent/DE69010001D1/de
Application granted granted Critical
Publication of DE69010001T2 publication Critical patent/DE69010001T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69010001T 1989-04-28 1990-04-26 Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika. Expired - Fee Related DE69010001T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34456589A 1989-04-28 1989-04-28
PCT/CA1990/000135 WO1990013563A1 (en) 1989-04-28 1990-04-26 Synthetic pseudomonas aeruginosa pilin peptide and related vaccines and diagnostics

Publications (2)

Publication Number Publication Date
DE69010001D1 true DE69010001D1 (de) 1994-07-21
DE69010001T2 DE69010001T2 (de) 1994-09-22

Family

ID=23351056

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69010001T Expired - Fee Related DE69010001T2 (de) 1989-04-28 1990-04-26 Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.

Country Status (9)

Country Link
US (2) US5445818A (de)
EP (1) EP0469045B1 (de)
JP (1) JP2963536B2 (de)
AT (1) ATE107313T1 (de)
AU (1) AU5533490A (de)
CA (3) CA1340530C (de)
DE (1) DE69010001T2 (de)
DK (1) DK0469045T3 (de)
WO (1) WO1990013563A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method
US5223604A (en) * 1991-06-25 1993-06-29 S.P.I. Synthetic Peptides Incorporated Pseudomonas exoenzyme s peptide composition and method
AU688953B2 (en) 1994-07-25 1998-03-19 Boehringer Mannheim Gmbh Determination of a specific immunoglobulin using multiple antigens
US6872398B2 (en) * 1995-12-22 2005-03-29 The United States Of America As Represented By The Secretary Of The Army Conjugate vaccine against gram-negative bacterial infections
US6270777B1 (en) * 1996-12-20 2001-08-07 University Technologies International Inc. Conserved metalloprotease epitopes
US7314632B1 (en) * 1997-07-11 2008-01-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pseudomonas exotoxin A-like chimeric immunogens
US20030054012A1 (en) * 2000-05-12 2003-03-20 Fitzgerald David J. Pseudomonas exotoxin a-like chimeric immunogens for eliciting a secretory iga-mediated immune response
ATE307208T1 (de) * 1997-07-11 2005-11-15 Us Gov Health & Human Serv Pseudomonas exotoxin-a-ähnliche chimerische immunogene
WO1999065511A2 (en) * 1998-06-12 1999-12-23 The Governors Of The University Of Alberta Composition and method for treatment of pseudomonas infection
US20030228324A1 (en) * 1999-05-06 2003-12-11 Malcolm Andrew J. Peptide compositions and methods of producing and using same
US6863896B1 (en) * 1999-10-26 2005-03-08 Chiron Corporation Plant lectins as mucosal adjuvants
WO2002060935A2 (en) * 2000-12-21 2002-08-08 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services A chimeric protein comprising non-toxic pseudomonas exotoxin a and type iv pilin sequences
US7132101B2 (en) * 2002-02-27 2006-11-07 Duquesne University Of The Holy Ghost Compositions and methods for eliciting an immune response to gram-negative bacterial infections
CA2583226A1 (en) 2004-10-04 2006-04-20 Trinity Biosystems, Inc. Methods and compositions for immunizing against pseudomonas infection
WO2007089272A2 (en) 2005-07-22 2007-08-09 The Regents Of The University Of Colorado, A Body Corporate Non-toxic biofilm inhibitor
WO2011094363A2 (en) 2010-01-26 2011-08-04 The Regents Of The University Of Colorado Influenza virus compositions and methods for universal vaccines
BR112016021383A2 (pt) 2014-03-24 2017-10-03 Genentech Inc Método para identificar um paciente com câncer que é susceptível ou menos susceptível a responder ao tratamento com um antagonista de cmet, método para identificar um paciente apresentando câncer previamente tratado, método para determinar a expressão do biomarcador hgf, antagonista anti-c-met e seu uso, kit de diagnóstico e seu método de preparo
CA3066026A1 (en) 2017-06-14 2018-12-20 Virometix Ag Cyclic peptides for protection against respiratory syncytial virus
WO2020127728A1 (en) 2018-12-20 2020-06-25 Virometix Ag Lipopeptide building blocks and synthetic virus-like particles
EP4216992A1 (de) 2020-09-28 2023-08-02 DBV Technologies Partikel mit einem rsv-f-protein zur verwendung bei der rsv-impfung

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048422A3 (de) * 1980-09-15 1983-08-24 Bactex Incorporated Haare von Pseudomonas-Aeruginosa und deren Verwendung als Impfstoffe gegen infektiöse P.Aeruginosa
US4443549A (en) * 1981-10-19 1984-04-17 Molecular Genetics, Inc. Production of monoclonal antibodies against bacterial adhesins
US4886663A (en) * 1983-01-03 1989-12-12 Scripps Clinic And Research Foundation Synthetic heat-stable enterotoxin polypeptide of Escherichia coli and multimers thereof
AU577045B2 (en) * 1983-07-23 1988-09-15 Zahnradfabrik Friedrichshafen Ag Pressure medium control device
DK219084D0 (da) * 1984-05-02 1984-05-02 Frederik Carl Peter Lindberg Antigen
CA1256370A (en) * 1984-02-24 1989-06-27 Yuzuru Homma Toxoids of elastase of pseudomonas aeruginosa origin
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
CA1319101C (en) * 1986-09-03 1993-06-15 Marta Iris Sabara Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules
JP2635742B2 (ja) * 1986-12-22 1997-07-30 トリオン、フォルスクニング‐オホ、ウトベクリングス、アクチェボラーグ 新規ポリペプチド及びその用途
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method

Also Published As

Publication number Publication date
US5445818A (en) 1995-08-29
EP0469045B1 (de) 1994-06-15
CA1340530C (en) 1999-05-04
ATE107313T1 (de) 1994-07-15
JPH04504719A (ja) 1992-08-20
CA2053924C (en) 2003-10-21
JP2963536B2 (ja) 1999-10-18
WO1990013563A1 (en) 1990-11-15
AU5533490A (en) 1990-11-29
DK0469045T3 (da) 1994-09-26
EP0469045A1 (de) 1992-02-05
US5612036A (en) 1997-03-18
CA2443232A1 (en) 1990-10-29
DE69010001T2 (de) 1994-09-22
CA2053924A1 (en) 1990-10-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee