DE69014125D1 - Künstliche bauchspeicheldrüsenperfundierungsvorrichtung. - Google Patents
Künstliche bauchspeicheldrüsenperfundierungsvorrichtung.Info
- Publication number
- DE69014125D1 DE69014125D1 DE69014125T DE69014125T DE69014125D1 DE 69014125 D1 DE69014125 D1 DE 69014125D1 DE 69014125 T DE69014125 T DE 69014125T DE 69014125 T DE69014125 T DE 69014125T DE 69014125 D1 DE69014125 D1 DE 69014125D1
- Authority
- DE
- Germany
- Prior art keywords
- islets
- hollow fiber
- suspended
- salivary gland
- perfusion device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3475—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate with filtrate treatment agent in the same enclosure as the membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1678—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/398,739 US5002661A (en) | 1989-08-25 | 1989-08-25 | Artificial pancreatic perfusion device |
PCT/US1990/000917 WO1991002498A1 (en) | 1989-08-25 | 1990-02-22 | Artificial pancreatic perfusion device |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69014125D1 true DE69014125D1 (de) | 1994-12-15 |
DE69014125T2 DE69014125T2 (de) | 1995-03-23 |
Family
ID=23576610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69014125T Expired - Fee Related DE69014125T2 (de) | 1989-08-25 | 1990-02-22 | Künstliche bauchspeicheldrüsenperfundierungsvorrichtung. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5002661A (de) |
EP (1) | EP0489014B1 (de) |
JP (1) | JPH04507051A (de) |
AT (1) | ATE113817T1 (de) |
AU (1) | AU641164B2 (de) |
CA (1) | CA2065390C (de) |
DE (1) | DE69014125T2 (de) |
DK (2) | DK0489014T3 (de) |
ES (1) | ES2063356T3 (de) |
WO (1) | WO1991002498A1 (de) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1231916B (it) * | 1989-05-29 | 1992-01-15 | Ampliscientifica S R L | Pancreas artificiale indossabile |
US5116493A (en) * | 1989-08-25 | 1992-05-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device with reseedable matrix |
US5116494A (en) * | 1989-08-25 | 1992-05-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device with temperature sensitive matrix |
US5744327A (en) * | 1990-02-20 | 1998-04-28 | Board Of Regents, The University Of Texas System | Methods for producing insulin in response to non-glucose secretagogues |
US5427940A (en) * | 1991-06-03 | 1995-06-27 | Board Of Regents, The University Of Texas System | Engineered cells producing insulin in response to glucose |
US5713888A (en) * | 1990-10-31 | 1998-02-03 | Baxter International, Inc. | Tissue implant systems |
US5344454A (en) * | 1991-07-24 | 1994-09-06 | Baxter International Inc. | Closed porous chambers for implanting tissue in a host |
BR9106205A (pt) * | 1990-10-31 | 1993-03-30 | Baxter Int | Dispositivo para implantacao em hospedeiro,processo de implantacao,dispositivo implantado,e recipiente de imunoisolamento |
US5314471A (en) * | 1991-07-24 | 1994-05-24 | Baxter International Inc. | Tissue inplant systems and methods for sustaining viable high cell densities within a host |
US5733336A (en) * | 1990-10-31 | 1998-03-31 | Baxter International, Inc. | Ported tissue implant systems and methods of using same |
DE4108772A1 (de) * | 1991-03-18 | 1992-09-24 | Inst Textil & Faserforschung | Implantierbares biohybrides organ |
US5800829A (en) * | 1991-04-25 | 1998-09-01 | Brown University Research Foundation | Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core |
DK0585368T3 (da) * | 1991-04-25 | 1998-03-16 | Univ Brown Res Found | Implanterbart biokompatibelt immunisolatorisk vehikel til afgivelse af udvalgte terapeutiske produkter |
US5792656A (en) * | 1991-06-03 | 1998-08-11 | Board Of Regents, The University Of Texas System | Methods of preparing genetically engineered cells that produce insulin in response to glucose |
US6773458B1 (en) | 1991-07-24 | 2004-08-10 | Baxter International Inc. | Angiogenic tissue implant systems and methods |
US5453278A (en) * | 1991-07-24 | 1995-09-26 | Baxter International Inc. | Laminated barriers for tissue implants |
EP1101457A3 (de) * | 1991-09-16 | 2001-11-07 | Atrium Medical Corporation | Implantierbare,eine kontrollierte Porosität aufweisende Vorrichtung mit einem Primärlumen |
US5370681A (en) * | 1991-09-16 | 1994-12-06 | Atrium Medical Corporation | Polyumenal implantable organ |
US5298206A (en) * | 1992-02-04 | 1994-03-29 | W. R. Grace & Co.-Conn. | Method and apparatus for casting hollow fiber membranes |
US5387237A (en) * | 1992-07-30 | 1995-02-07 | The University Of Toledo | Bioartificial pancreas |
US5425764A (en) * | 1992-07-30 | 1995-06-20 | The University Of Toledo | Bioartificial pancreas |
GB9311784D0 (en) * | 1993-06-08 | 1993-07-28 | Univ Alberta | Vascular bioartificial organ |
ES2138665T3 (es) | 1993-08-10 | 2000-01-16 | Gore & Ass | Dispositivo para encapsular celulas. |
EP1179350A3 (de) * | 1993-08-12 | 2003-01-02 | Cytotherapeutics, Inc. | Enkapsuliertes Zellsystem zur Implantation in dem menschlichen ZNC |
US5908623A (en) * | 1993-08-12 | 1999-06-01 | Cytotherapeutics, Inc. | Compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules |
JPH08503715A (ja) * | 1993-09-24 | 1996-04-23 | バクスター、インターナショナル、インコーポレイテッド | 埋め込み装置の血管化を促進するための方法 |
US5550050A (en) * | 1994-04-15 | 1996-08-27 | Cytotherapeutics, Inc. | Method for implanting encapsulated cells in a host |
US6156305A (en) * | 1994-07-08 | 2000-12-05 | Baxter International Inc. | Implanted tumor cells for the prevention and treatment of cancer |
US5935849A (en) * | 1994-07-20 | 1999-08-10 | Cytotherapeutics, Inc. | Methods and compositions of growth control for cells encapsulated within bioartificial organs |
US5858747A (en) * | 1994-07-20 | 1999-01-12 | Cytotherapeutics, Inc. | Control of cell growth in a bioartificial organ with extracellular matrix coated microcarriers |
US6495364B2 (en) * | 1995-05-23 | 2002-12-17 | Neurotech, S.A. | Mx-1 conditionally immortalized cells |
US5681740A (en) * | 1995-06-05 | 1997-10-28 | Cytotherapeutics, Inc. | Apparatus and method for storage and transporation of bioartificial organs |
US5741334A (en) * | 1995-06-07 | 1998-04-21 | Circe Biomedical, Inc. | Artificial pancreatic perfusion device |
WO1997010807A1 (en) * | 1995-09-22 | 1997-03-27 | Gore Hybrid Technologies, Inc. | Improved cell encapsulation device |
US5854067A (en) * | 1996-01-19 | 1998-12-29 | Board Of Regents, The University Of Texas System | Hexokinase inhibitors |
US6087129A (en) * | 1996-01-19 | 2000-07-11 | Betagene, Inc. | Recombinant expression of proteins from secretory cell lines |
WO1997030778A1 (en) * | 1996-02-23 | 1997-08-28 | Circle Biomedical, Inc. | Novel artificial pancreas |
US5976780A (en) * | 1996-07-16 | 1999-11-02 | Shah; Kumarpal A. | Encapsulated cell device |
ZA9710342B (en) * | 1996-11-25 | 1998-06-10 | Alza Corp | Directional drug delivery stent and method of use. |
US5985151A (en) * | 1997-12-19 | 1999-11-16 | Saman Ahmadi | Method and apparatus of membrane separation |
US6303355B1 (en) | 1999-03-22 | 2001-10-16 | Duke University | Method of culturing, cryopreserving and encapsulating pancreatic islet cells |
US6365385B1 (en) | 1999-03-22 | 2002-04-02 | Duke University | Methods of culturing and encapsulating pancreatic islet cells |
US8252044B1 (en) | 2000-11-17 | 2012-08-28 | Advanced Bio Prosthestic Surfaces, Ltd. | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
US9107605B2 (en) * | 2000-11-17 | 2015-08-18 | Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
US10398830B2 (en) * | 2000-11-17 | 2019-09-03 | Vactronix Scientific, Llc | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
CA2450650C (en) * | 2002-12-24 | 2007-08-28 | An-Go-Gen Inc. | Encapsulated cell therapy |
JP5247468B2 (ja) * | 2005-12-30 | 2013-07-24 | ニューロテック ユーエスエー, インコーポレイテッド | 生物活性分子の送達のための微粒子化デバイスおよびその使用方法 |
US9540630B2 (en) * | 2008-09-17 | 2017-01-10 | Beta O2 Technologies Ltd. | Optimization of alginate encapsulation of islets for transplantation |
US9446168B2 (en) | 2010-06-07 | 2016-09-20 | Beta-O2 Technologies Ltd. | Multiple-layer immune barrier for donor cells |
EP2356227B1 (de) | 2008-11-14 | 2018-03-28 | Viacyte, Inc. | Einkapselung von aus menschlichen pluripotenten stammzellen abgeleiteten pankreaszellen |
JP2012524544A (ja) * | 2009-04-23 | 2012-10-18 | ニューロテック ユーエスエー, インコーポレイテッド | プロスタグランジンF2アルファ(PGF2a)を産生する細胞系およびその使用 |
AU2011336592A1 (en) | 2010-12-02 | 2013-07-11 | Neurotech Usa, Inc. | Cell lines that secrete anti-angiogenic antibody-scaffolds and soluble receptors and uses thereof |
WO2014138691A1 (en) * | 2013-03-07 | 2014-09-12 | Viacyte, Inc. | 3-dimensional large capacity cell encapsulation device assembly |
USD720469S1 (en) | 2013-03-07 | 2014-12-30 | Viacyte, Inc. | Cell encapsulation device |
US10456356B2 (en) | 2015-05-27 | 2019-10-29 | Neurotech Usa, Inc. | Use of encapsulated cell therapy for treatment of ophthalmic disorders |
JP7088564B2 (ja) | 2016-11-10 | 2022-06-21 | ヴィアサイト,インコーポレイテッド | 細胞送達装置におけるpdx1膵臓内胚葉細胞及びその方法 |
EP3398558A1 (de) * | 2017-05-02 | 2018-11-07 | Carlo Andretta | Körperperfusionssystem |
DE102018006061A1 (de) | 2018-08-01 | 2020-02-06 | Universität Duisburg-Essen | Implantat |
WO2021061940A1 (en) | 2019-09-27 | 2021-04-01 | Isla Technologies, Inc. | Bioartificial pancreas |
US11305234B1 (en) | 2021-09-16 | 2022-04-19 | King Abdulaziz University | Supercoil filtration unit |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3734851A (en) * | 1969-12-29 | 1973-05-22 | K Matsumura | Method and device for purifying blood |
CA1027304A (en) * | 1973-06-06 | 1978-03-07 | Theodore E. Spielberg | Artificial gland structure |
CA1085104A (en) * | 1977-03-21 | 1980-09-09 | Anthony M. Sun | Artificial endocrine pancreas |
US4169477A (en) * | 1977-07-07 | 1979-10-02 | Carbomedics, Inc. | Anastomatic couplings |
US4242459A (en) * | 1978-11-02 | 1980-12-30 | Chick William L | Cell culture device |
US4242460A (en) * | 1978-12-26 | 1980-12-30 | Chick William L | Cell culture device |
US4378016A (en) * | 1981-07-15 | 1983-03-29 | Biotek, Inc. | Artificial endocrine gland containing hormone-producing cells |
FR2531333B1 (fr) * | 1982-08-09 | 1986-04-04 | Centre Nat Rech Scient | Pancreas bio-artificiel a ultrafiltration |
EP0127989A3 (de) * | 1983-06-01 | 1986-03-26 | Connaught Laboratories Limited | Mikroverkapselung von lebenden Gewebe und Zellen |
WO1985005630A1 (en) * | 1984-06-01 | 1985-12-19 | Karyon Technology, Incorporated | Tissue culture and production in permeable gels |
-
1989
- 1989-08-25 US US07/398,739 patent/US5002661A/en not_active Expired - Lifetime
-
1990
- 1990-02-22 DK DK90908389.1T patent/DK0489014T3/da active
- 1990-02-22 ES ES90908389T patent/ES2063356T3/es not_active Expired - Lifetime
- 1990-02-22 AT AT90908389T patent/ATE113817T1/de not_active IP Right Cessation
- 1990-02-22 DE DE69014125T patent/DE69014125T2/de not_active Expired - Fee Related
- 1990-02-22 WO PCT/US1990/000917 patent/WO1991002498A1/en active IP Right Grant
- 1990-02-22 AU AU57333/90A patent/AU641164B2/en not_active Ceased
- 1990-02-22 JP JP2508112A patent/JPH04507051A/ja active Pending
- 1990-02-22 CA CA002065390A patent/CA2065390C/en not_active Expired - Fee Related
- 1990-02-22 EP EP90908389A patent/EP0489014B1/de not_active Expired - Lifetime
-
1992
- 1992-02-24 DK DK92231A patent/DK23192D0/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK23192A (da) | 1992-02-24 |
US5002661A (en) | 1991-03-26 |
JPH04507051A (ja) | 1992-12-10 |
EP0489014B1 (de) | 1994-11-09 |
DK23192D0 (da) | 1992-02-24 |
AU5733390A (en) | 1991-04-03 |
CA2065390A1 (en) | 1991-02-26 |
DK0489014T3 (da) | 1995-05-01 |
ATE113817T1 (de) | 1994-11-15 |
CA2065390C (en) | 1996-09-24 |
ES2063356T3 (es) | 1995-01-01 |
WO1991002498A1 (en) | 1991-03-07 |
AU641164B2 (en) | 1993-09-16 |
EP0489014A1 (de) | 1992-06-10 |
DE69014125T2 (de) | 1995-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: CIRCE BIOMEDICAL, INC., LEXINGTON, MASS., US |
|
8339 | Ceased/non-payment of the annual fee |