DE69021263D1 - Fibronektinbindungsprotein und dessen Herstellung. - Google Patents

Fibronektinbindungsprotein und dessen Herstellung.

Info

Publication number
DE69021263D1
DE69021263D1 DE69021263T DE69021263T DE69021263D1 DE 69021263 D1 DE69021263 D1 DE 69021263D1 DE 69021263 T DE69021263 T DE 69021263T DE 69021263 T DE69021263 T DE 69021263T DE 69021263 D1 DE69021263 D1 DE 69021263D1
Authority
DE
Germany
Prior art keywords
fibronectin binding
production
binding protein
protein
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69021263T
Other languages
English (en)
Other versions
DE69021263T2 (de
Inventor
Magnus Hoeoek
Klas Joensson
Kjell Martin Lindberg
Lars Christer Signaes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Laval Agri International AB
Original Assignee
Alfa Laval Agri International AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Laval Agri International AB filed Critical Alfa Laval Agri International AB
Application granted granted Critical
Publication of DE69021263D1 publication Critical patent/DE69021263D1/de
Publication of DE69021263T2 publication Critical patent/DE69021263T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69021263T 1989-05-11 1990-05-04 Fibronektinbindungsprotein und dessen Herstellung. Expired - Lifetime DE69021263T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8901687A SE8901687D0 (sv) 1989-05-11 1989-05-11 Fibronectin binding protein as well as its preparation

Publications (2)

Publication Number Publication Date
DE69021263D1 true DE69021263D1 (de) 1995-09-07
DE69021263T2 DE69021263T2 (de) 1996-01-04

Family

ID=20375920

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69021263T Expired - Lifetime DE69021263T2 (de) 1989-05-11 1990-05-04 Fibronektinbindungsprotein und dessen Herstellung.

Country Status (15)

Country Link
US (3) US5175096A (de)
EP (1) EP0397633B1 (de)
JP (1) JP3077993B2 (de)
AT (1) ATE125867T1 (de)
AU (1) AU630950B2 (de)
CA (1) CA2016521C (de)
DE (1) DE69021263T2 (de)
DK (1) DK0397633T3 (de)
ES (1) ES2077666T3 (de)
FI (1) FI102768B1 (de)
GR (1) GR3017946T3 (de)
IE (1) IE72968B1 (de)
NO (1) NO300069B1 (de)
NZ (1) NZ233614A (de)
SE (1) SE8901687D0 (de)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801894D0 (sv) * 1988-05-20 1988-05-20 Alfa Laval Agri Int Fibronektinbindande protein
SE8901687D0 (sv) * 1989-05-11 1989-05-11 Alfa Laval Agri Int Fibronectin binding protein as well as its preparation
US5440014A (en) * 1990-08-10 1995-08-08 H+E,Uml/Oo/ K; Magnus Fibronectin binding peptide
US7279162B1 (en) 1990-10-22 2007-10-09 Henry M. Jackson Foundation For The Advancement Of Military Medicine Isolated broadly reactive opsonic immunoglobulin for treating a pathogenic coagulase-negative staphylococcus infection
US5851794A (en) * 1990-10-22 1998-12-22 Alfa Laval Ab Collagen binding protein as well as its preparation
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5980908A (en) * 1991-12-05 1999-11-09 Alfa Laval Ab Bacterial cell surface protein with fibronectin, fibrinogen, collagen and laminin binding ability, process for the manufacture of the protein and prophylactic treatment
NZ261149A (en) * 1993-02-05 1997-07-27 Smithkline Beecham Plc Staphylococcus aureus polypeptides and monoclonal antibodies therefrom, their production and use
US5492819A (en) * 1993-09-23 1996-02-20 Genencor International, Inc. Recovery of insoluble biosynthetic products
US7083979B1 (en) * 1994-03-25 2006-08-01 Indiana University Foundation Methods for enhanced retroviral-mediated gene transfer
US6033907A (en) * 1995-09-29 2000-03-07 Indiana University Foundation Enhanced virus-mediated DNA transfer
US6933366B2 (en) * 1996-12-27 2005-08-23 Tripep Ab Specificity exchangers that redirect antibodies to bacterial adhesion receptors
US6660842B1 (en) * 1994-04-28 2003-12-09 Tripep Ab Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen
US6040137A (en) * 1995-04-27 2000-03-21 Tripep Ab Antigen/antibody specification exchanger
US20040247611A1 (en) * 1994-05-23 2004-12-09 Montana State University Identification of pathogen-ligand interactions
GB9415902D0 (en) * 1994-08-05 1994-09-28 Smithkline Beecham Plc Method of treatment
KR100793625B1 (ko) * 1995-09-29 2008-01-11 인디아나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 바이러스-매개된 ｄｎａ 전달을 향상시키는 방법에 의해생산된 생존성 세포 집단 및 이를 포함하는 세포 조성물
US6013482A (en) * 1996-10-15 2000-01-11 Smithkline Beecham Plc Cell surface protein compounds
US5858709A (en) * 1996-10-15 1999-01-12 Smithkline Beecham P.L.C. Fibronectin binding protein B compounds
JPH11505130A (ja) * 1995-10-16 1999-05-18 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 新規な細胞表面タンパク質化合物
GB9521146D0 (en) * 1995-10-16 1995-12-20 Smithkline Beecham Plc Novel compounds
US6274376B1 (en) * 1996-02-20 2001-08-14 Smithkline Beecham Corporation ClpL
US6348584B1 (en) * 1996-10-17 2002-02-19 John Edward Hodgson Fibronectin binding protein compounds
EP0971740B1 (de) * 1997-01-21 2009-08-19 THE TEXAS A&M UNIVERSITY SYSTEM Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikörper dagegen und therapeutische anwendung
US6685943B1 (en) 1997-01-21 2004-02-03 The Texas A&M University System Fibronectin binding protein compositions and methods of use
US6610293B1 (en) * 1997-06-16 2003-08-26 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria
US6270992B1 (en) * 1997-07-29 2001-08-07 Smithkline Beecham Corporation Histidine kinase of Staphylococcus aureus
GB9720633D0 (en) * 1997-09-29 1997-11-26 Univ Bristol BHV-2 vector
US7250494B2 (en) * 1998-06-15 2007-07-31 Biosynexus Incorporated Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria
US6692739B1 (en) 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
US6703025B1 (en) 1998-08-31 2004-03-09 Inhibitex, Inc. Multicomponent vaccines
US20020092987A1 (en) * 1998-09-05 2002-07-18 Taehee Cho Photo detect device using quantum dots and materialization method thereof
SK782002A3 (en) 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
WO2002090502A2 (en) * 2001-05-08 2002-11-14 The Texas A & M University System Highly conserved proteins from gram-positive bacteria
US6835378B2 (en) 2001-05-11 2004-12-28 The Texas A&M University System University Method and compositions for inhibiting thrombin-induced coagulation
JP4424984B2 (ja) 2001-06-15 2010-03-03 インヒビテックス インコーポレーテッド コアグラーゼ陰性ブドウ球菌および黄色ブドウ球菌由来の表面蛋白質を認識する、交差反応性モノクローナルおよびポリクローナル抗体
US7115264B2 (en) * 2001-11-05 2006-10-03 Inhibitex Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections
US7335359B2 (en) 2003-02-06 2008-02-26 Tripep Ab Glycosylated specificity exchangers
AU2004209457A1 (en) * 2003-02-06 2004-08-19 Tripep Ab Antigen/antibody or ligand/receptor glycosylated specificity exchangers
US9296795B2 (en) * 2003-03-07 2016-03-29 Wyeth Holdings, Llc. Polysaccharide-staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections
US7348004B2 (en) * 2003-05-06 2008-03-25 Syntonix Pharmaceuticals, Inc. Immunoglobulin chimeric monomer-dimer hybrids
TWI353991B (en) * 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
WO2004100882A2 (en) * 2003-05-06 2004-11-25 Syntonix Pharmaceuticals, Inc. Inhibition of drug binding to serum albumin
WO2004101740A2 (en) 2003-05-06 2004-11-25 Syntonix Pharmaceuticals, Inc. Clotting factor-fc chimeric proteins to treat hemophilia
CN1953991A (zh) 2004-05-21 2007-04-25 惠氏公司 变异的金黄色葡萄球菌纤连蛋白结合蛋白
KR101508563B1 (ko) 2004-09-22 2015-04-07 글락소스미스클라인 바이오로지칼즈 에스.에이. 스태필로코쿠스에 대한 예방접종에 사용하기 위한 면역원성 조성물
US20100021503A1 (en) 2006-03-30 2010-01-28 Glaxosmithkline Biologicals S.A. Immunogenic composition
US20090092631A1 (en) * 2007-03-26 2009-04-09 Tripep Ab Glycosylated specificity exchangers that induce an antibody dependent cellular cytotoxicity (adcc) response
EP2185190B1 (de) * 2007-08-31 2015-06-24 University Of Chicago Verfahren und zusammensetzungen zur immunisierung gegen durch staphylokokken vermittelte lungenerkrankungen und -leiden
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
WO2010014304A1 (en) * 2008-07-29 2010-02-04 University Of Chicago Compositions and methods related to staphylococcal bacterium proteins
JP2012504660A (ja) 2008-10-06 2012-02-23 ユニバーシティ オブ シカゴ 細菌ｅａｐ、ｅｍｐおよび／またはａｄｓａタンパク質に関連する組成物および方法
SI3281947T1 (sl) 2009-04-03 2020-07-31 The University Of Chicago Sestave in metode v zvezi z variantami proteina A (SPA)
GB0913680D0 (en) 2009-08-05 2009-09-16 Glaxosmithkline Biolog Sa Immunogenic composition
EP2531208A4 (de) * 2010-02-03 2013-07-03 Univ Rochester Behandlung fibrosevermittelter leiden mithilfe fibronectinbindender proteine und polypeptide
EP2555794A4 (de) 2010-04-05 2014-01-15 Univ Chicago Zusammensetzungen und verfahren im zusammenhang mit protein-a-(spa)-antikörpern als immunreaktionsverstärker
CN103037885B (zh) 2010-07-02 2015-08-26 芝加哥大学 与蛋白A(SpA)变体相关的组合物和方法
JP5793194B2 (ja) 2010-09-09 2015-10-14 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ 感染防御ブドウ球菌抗原が関与する方法および組成物
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
CA2845259A1 (en) 2011-08-15 2013-02-21 The University Of Chicago Compositions and methods related to antibodies to staphylococcal protein a
EP2844275B1 (de) 2012-04-26 2020-05-13 University of Chicago Staphylokokken-coagulase-antigene und verfahren zu deren verwendung
JP6251730B2 (ja) 2012-04-26 2017-12-20 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ 黄色ブドウ球菌（ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）疾患の間にコアグラーゼ活性を中和する抗体に関連した組成物および方法
SG11201505926VA (en) 2013-03-15 2015-09-29 Biogen Ma Inc Factor ix polypeptide formulations
CN105384800B (zh) * 2015-12-07 2019-01-25 黑龙江八一农垦大学 金黄色葡萄球菌taf融合蛋白制备方法及其应用
EP3257862A1 (de) * 2016-06-16 2017-12-20 ETH Zürich Fibronectinbindende peptide zur verwendung bei der diagnose eines tumors oder von fibrose und therapie
EP4038091A1 (de) 2019-10-02 2022-08-10 Janssen Vaccines & Prevention B.V. Staphylococcus-peptide und verfahren zur verwendung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917818A (en) * 1970-01-14 1975-11-04 Agricura Labor Ltd Treatment of mastitis in cows, the product for this treatment and to the production of said product
DE2644622C3 (de) * 1976-10-02 1979-11-29 Behringwerke Ag, 3550 Marburg Extraktion von Mikroorganismen und diese enthaltende diagnostische Mittel
SE445013B (sv) * 1979-06-21 1986-05-26 Landstingens Inkopscentral Medel for att forebygga eller behandla infektioner hos menniskor och djur
US4425330A (en) * 1981-05-20 1984-01-10 Cornell Research Foundation, Inc. Bovine mastitis vaccine and method for detecting efficacy thereof
SE446688C (sv) * 1982-09-14 1989-08-01 Magnus Hoeoek Medel foer avlaegsnande av mikroorganismer fraan vaevnader, vilket bestaar av ett protein som kan bindas till mikroorganismerna
DK219084D0 (da) * 1984-05-02 1984-05-02 Frederik Carl Peter Lindberg Antigen
US5189015A (en) * 1984-05-30 1993-02-23 Alfa-Laval Agri International Ab Method for prophylactic treatment of the colonization of a Staphylococcus aureus bacterial strain by bacterial cell surface protein with fibronectin and fibrinogen binding ability
SE454403B (sv) * 1984-05-30 1988-05-02 Alfa Laval Agri Int Anvendning av ett cellyteprotein med fibronektin-, fibrinogen-, kollagen-, och/eller lamininbindande egenskaper vid framstellning av sarbehandlingsmedel
US5320951A (en) * 1987-06-01 1994-06-14 Hoeoek Magnus Fibronectin binding protein as well as its preparation
US5571514A (en) * 1987-06-01 1996-11-05 Alfa Laval Ab Fibronectin binding protein as well as its preparation
SE8702272L (sv) * 1987-06-01 1988-12-02 Alfa Laval Agri Int Fibronektinbindande protein samt dess framstaellning
SE8801723D0 (sv) * 1988-05-06 1988-05-06 Staffan Normark Fibronectin binding protein as well as its preparation
SE8801894D0 (sv) * 1988-05-20 1988-05-20 Alfa Laval Agri Int Fibronektinbindande protein
SE8901687D0 (sv) * 1989-05-11 1989-05-11 Alfa Laval Agri Int Fibronectin binding protein as well as its preparation
SE9002617D0 (sv) * 1990-08-10 1990-08-10 Alfa Laval Agri Int A fibronectin binding peptide

Also Published As

Publication number Publication date
AU630950B2 (en) 1992-11-12
NO902082L (no) 1990-11-12
EP0397633A3 (de) 1991-07-31
DE69021263T2 (de) 1996-01-04
US5840846A (en) 1998-11-24
DK0397633T3 (da) 1996-01-02
FI902350A0 (fi) 1990-05-10
CA2016521A1 (en) 1990-11-11
NO902082D0 (no) 1990-05-10
ATE125867T1 (de) 1995-08-15
CA2016521C (en) 2002-02-05
ES2077666T3 (es) 1995-12-01
NZ233614A (en) 1991-12-23
IE901696L (en) 1990-11-11
JPH03272687A (ja) 1991-12-04
AU5481890A (en) 1990-11-15
EP0397633A2 (de) 1990-11-14
FI102768B (fi) 1999-02-15
IE72968B1 (en) 1997-05-07
SE8901687D0 (sv) 1989-05-11
US5652217A (en) 1997-07-29
EP0397633B1 (de) 1995-08-02
US5175096A (en) 1992-12-29
FI102768B1 (fi) 1999-02-15
JP3077993B2 (ja) 2000-08-21
GR3017946T3 (en) 1996-02-29
NO300069B1 (no) 1997-04-01

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Legal Events

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