DE69021309T2 - Magnetische Teilchen verwendender Immunotest. - Google Patents

Magnetische Teilchen verwendender Immunotest.

Info

Publication number
DE69021309T2
DE69021309T2 DE69021309T DE69021309T DE69021309T2 DE 69021309 T2 DE69021309 T2 DE 69021309T2 DE 69021309 T DE69021309 T DE 69021309T DE 69021309 T DE69021309 T DE 69021309T DE 69021309 T2 DE69021309 T2 DE 69021309T2
Authority
DE
Germany
Prior art keywords
immunotest
magnetic particles
particles
magnetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69021309T
Other languages
English (en)
Other versions
DE69021309D1 (de
Inventor
Masahisa Okada
Yoshihiro Ashihara
Akira Yano
Masao Oishi
Katsuaki Yoshioka
Toshiomi Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Nippon Paint Co Ltd
Original Assignee
Fujirebio Inc
Nippon Paint Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujirebio Inc, Nippon Paint Co Ltd filed Critical Fujirebio Inc
Publication of DE69021309D1 publication Critical patent/DE69021309D1/de
Application granted granted Critical
Publication of DE69021309T2 publication Critical patent/DE69021309T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/10—Magnetic particle immunoreagent carriers the magnetic material being used to coat a pre-existing polymer particle but not being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/86—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/90—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids characterised by small molecule linker used to couple immunoreagents to magnetic particles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
DE69021309T 1989-09-29 1990-09-26 Magnetische Teilchen verwendender Immunotest. Expired - Lifetime DE69021309T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1252051A JP2979414B2 (ja) 1989-09-29 1989-09-29 磁性粒子およびそれを用いた免疫測定法

Publications (2)

Publication Number Publication Date
DE69021309D1 DE69021309D1 (de) 1995-09-07
DE69021309T2 true DE69021309T2 (de) 1996-02-01

Family

ID=17231885

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69021309T Expired - Lifetime DE69021309T2 (de) 1989-09-29 1990-09-26 Magnetische Teilchen verwendender Immunotest.

Country Status (8)

Country Link
US (1) US5320944A (de)
EP (1) EP0420186B1 (de)
JP (1) JP2979414B2 (de)
KR (1) KR100206159B1 (de)
AU (1) AU641687B2 (de)
CA (1) CA2026515C (de)
DE (1) DE69021309T2 (de)
ES (1) ES2077618T3 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736349A (en) * 1989-09-29 1998-04-07 Nippon Paint Co., Ltd. Magnetic particle and immunoassay using the same
EP0585868B1 (de) * 1992-08-31 2000-03-01 Fujirebio Inc. Magnetisches Teilchen und seine Verwendung in einem Immunotest
CA2166705C (en) * 1993-07-08 2004-11-09 Mitsuo Isomura Magnetic particles with gelatin and immunoassay using the same
EP0769195B1 (de) * 1994-07-07 1999-01-20 Chiron Diagnostics Corporation Hochdispergierte magnetische metalloxidteilchen,produktionsverfahren und anwendung
JPH08136546A (ja) * 1994-11-15 1996-05-31 Bio Sensor Kenkyusho:Kk 物質分析法
US5858534A (en) * 1995-09-05 1999-01-12 Solid Phase Sciences Corp. Method of making and using derivatized paramagnetic polymer beads
US5779985A (en) * 1995-12-18 1998-07-14 Solid Phase Sciences Corporation Reaction plenum
JP3624543B2 (ja) * 1996-05-02 2005-03-02 東ソー株式会社 免疫反応試薬及びその製造方法
EP0991943A1 (de) * 1997-06-18 2000-04-12 Innova Gesellschaft Zur Entwicklung Und Vermarktung Innovativer Produkte MBH Magnetische partikel mit biologisch aktiven rezeptoren
US7454907B1 (en) 1998-11-20 2008-11-25 Hydro-Gear Limited Partnership Hydrostatic transmission
DE10042023C2 (de) * 2000-08-08 2003-04-10 Biognostic Ag Kapseln, die feste Teilchen signalerzeugender Substanzen einkapseln, und deren Verwendung bei Bioassays zum Nachweis von Zielmolekülen in einer Probe
US20020164659A1 (en) * 2000-11-30 2002-11-07 Rao Galla Chandra Analytical methods and compositions
US6919035B1 (en) * 2001-05-18 2005-07-19 Ensci Inc. Metal oxide coated polymer substrates
JP4072994B2 (ja) * 2001-10-11 2008-04-09 学校法人日本大学 磁性粒子
US8367013B2 (en) 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US7282540B2 (en) * 2002-03-25 2007-10-16 Jsr Corporation Process for producing particles for diagnostic reagent
US6797782B2 (en) * 2002-03-25 2004-09-28 Jsr Corporation Process for producing particles for diagnostic reagent
GB0215185D0 (en) 2002-07-01 2002-08-07 Genovision As Binding a target substance
US7314763B2 (en) 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
JP3783677B2 (ja) * 2002-10-29 2006-06-07 株式会社日立製作所 生体物質精製方法および生体物質精製用キットおよび生体物質分析システム
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US7851209B2 (en) * 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7632688B2 (en) 2003-04-16 2009-12-15 Sekisui Chemical Co., Ltd. Particle having magnetic material incorporated therein, process for producing the same, particle for immunoassay and method of immunoassay
US6986913B2 (en) * 2003-07-17 2006-01-17 Dynal Biotech Asa Process
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US20050112703A1 (en) * 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
DE10355409A1 (de) * 2003-11-25 2005-06-30 Magnamedics Gmbh Sphärische, magnetische Silicagel-Träger mit vergrößerter Oberfläche für die Aufreinigung von Nukleinsäuren
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
KR100580642B1 (ko) * 2004-01-12 2006-05-16 삼성전자주식회사 표면에 활성화된 카르복실기를 갖는 기판을 이용하여 생물분자를 고체 기판상에 고밀도로 고정화하는 방법 및 그에 의하여 제조되는 마이크로어레이
TWI277632B (en) * 2004-12-14 2007-04-01 Nat Univ Chung Cheng Magnetic polymer microbeads and a method for preparing the same
KR100702671B1 (ko) 2005-01-20 2007-04-03 한국과학기술원 스마트 자성 나노 스피어 제제 및 이의 제조방법
US20080124738A1 (en) * 2005-03-01 2008-05-29 Pritest, Inc Compositions and methods of testing for tuberculosis and mycobacterium infection
JP4655711B2 (ja) * 2005-03-22 2011-03-23 Ｊｓｒ株式会社 磁性体複合粒子の製造方法
CN1325518C (zh) * 2005-09-09 2007-07-11 李勇 人细胞膜抗原的保存方法及磁性粒子包被人细胞膜抗原
WO2007139243A1 (en) * 2006-05-30 2007-12-06 Ewha University-Industry Collaboration Foundation Methods and kits for in situ measurement of enzyme activity and amount using single measurement system
US8030376B2 (en) 2006-07-12 2011-10-04 Minusnine Technologies, Inc. Processes for dispersing substances and preparing composite materials
US20100018674A1 (en) * 2008-07-22 2010-01-28 Donald John Enzinna Reservoir with moveable partition for quick recovery
KR100988512B1 (ko) 2008-09-30 2010-10-20 한국과학기술연구원 코어-쉘 구조의 자성 복합 입자 및 그 제조 방법
WO2010149150A2 (de) 2009-06-22 2010-12-29 Deklatec Gmbh Farblose, magnetische polymerpartikel für den hochempfindlichen nachweis von biologischen substanzen und pathogenen im rahmen der bioanalytik und diagnostik
DE102009059112A1 (de) 2009-12-18 2011-06-22 Biotype Diagnostic GmbH, 01109 Eine Vorrichtung zur Bestimmung molekularer Wechselwirkungen, sowie eine Folie zur Herstellung einer solchen
US20170095579A1 (en) * 2011-01-31 2017-04-06 Korea University Research And Business Foundation Composition for target substance detection comprising magnetic nanoparticle having a curie temperature which is within biocompatible temperature range and system for target substance detection
KR101379971B1 (ko) * 2011-01-31 2014-04-10 고려대학교 산학협력단 생체 적합 온도 내에서 큐리 온도를 가지는 자성 나노입자 및 그 제조 방법
KR102007061B1 (ko) 2011-12-09 2019-08-02 앵스띠뛰 파스퇴르 다중 면역 스크리닝 분석
CN104080840B (zh) 2012-01-18 2016-08-31 芮宝生医股份有限公司 磁性微粒复合物的制作方法
CN105102979B (zh) 2013-01-29 2017-05-03 生物辐射海法有限公司 利用磁性纳米粒子的检测测定法
CA2923817C (en) * 2013-09-09 2021-12-28 Lab-On-A-Bead Ab Manufacture of magnetic particles
WO2015068715A1 (ja) 2013-11-06 2015-05-14 富士レビオ株式会社 抗ｈｔｌｖ抗体の免疫測定における非特異反応の低減方法
CZ305599B6 (cs) * 2014-08-01 2015-12-30 Univerzita Pardubice Způsob separace biopolymerních molekul a nosič pro využití při tomto způsobu
CA2984506A1 (en) 2015-05-01 2016-11-10 BioLegend, Inc. Stable nanomagnetic particle dispersions
EP4134427A1 (de) 2016-04-30 2023-02-15 Biolegend, Inc. Zusammensetzungen und verfahren zur durchführung von magnetisboyanttrennungen
CN107422129A (zh) * 2017-01-15 2017-12-01 北京科跃中楷生物技术有限公司 一种超敏的心肌肌钙蛋白i磁微球免疫比浊检测方法及检测试剂盒
CN211905389U (zh) 2017-02-21 2020-11-10 迈迪科泰斯芬兰公司 非侵入性脑损伤诊断装置
CN107402308A (zh) * 2017-06-21 2017-11-28 北京科跃中楷生物技术有限公司 Il‑6定量检测试剂盒及其制备方法
JPWO2021193763A1 (de) 2020-03-25 2021-09-30
CN113333024B (zh) * 2021-05-31 2022-03-25 云南大学 一种具有过氧化物酶催化活性的磁性纳米酶材料及其检测诺如病毒的试剂盒和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582956A (en) * 1976-07-30 1981-01-21 Ici Ltd Composite magnetic particles
US4335094A (en) * 1979-01-26 1982-06-15 Mosbach Klaus H Magnetic polymer particles
US4438239A (en) * 1981-03-30 1984-03-20 California Institute Of Technology Microsphere coated substrate containing reactive aldehyde groups
NO155316C (no) * 1982-04-23 1987-03-11 Sintef Fremgangsmaate for fremstilling av magnetiske polymerpartikler.
US4672040A (en) * 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
GB8401368D0 (en) * 1984-01-19 1984-02-22 Amersham Int Plc Assay method
JPS62197425A (ja) * 1986-02-25 1987-09-01 Toyo Soda Mfg Co Ltd 球状熱可塑性樹脂の製造方法
US4978614A (en) * 1988-10-26 1990-12-18 Tropix, Inc. Method of detecting a substance using enzymatically-induced decomposition of dioxetanes
BR8707399A (pt) * 1986-07-24 1988-09-13 Quest Systems Inc Metodo de detectar uma substancia usando decomposicao enzimaticamente induzida de dioxetanos
JPS6365085A (ja) * 1986-09-05 1988-03-23 Nippon Paint Co Ltd 粒子または繊維状物のフエライト被覆方法
EP0344270B1 (de) * 1987-10-26 1994-11-30 Baxter Diagnostics Inc. Verfahren zur herstellung magnetisch empfindlicher polymerteilchen und deren anwendung
AU620838B2 (en) * 1987-10-26 1992-02-27 Dade International Inc. Process for producing magnetically responsive polymer particles and application thereof

Also Published As

Publication number Publication date
DE69021309D1 (de) 1995-09-07
EP0420186B1 (de) 1995-08-02
AU6328690A (en) 1991-04-11
EP0420186A2 (de) 1991-04-03
CA2026515A1 (en) 1991-03-30
JP2979414B2 (ja) 1999-11-15
US5320944A (en) 1994-06-14
KR100206159B1 (ko) 1999-07-01
AU641687B2 (en) 1993-09-30
CA2026515C (en) 2001-12-25
KR910006725A (ko) 1991-04-29
JPH03115862A (ja) 1991-05-16
ES2077618T3 (es) 1995-12-01
EP0420186A3 (en) 1991-07-31

Similar Documents

Publication Publication Date Title
DE69021309T2 (de) Magnetische Teilchen verwendender Immunotest.
DE69102708D1 (de) Magnetische teilchen.
DE59003260D1 (de) Magnetsystem.
DE69013850T2 (de) Magnetrührer.
FI903108A0 (fi) Paramagnetiska foereningar.
FI892835A (fi) Elektromagnetisk broms foersedd med faestkaekar.
DE68912045T2 (de) Magnetische Einrichtung.
FI901652A0 (fi) Genomstroemningsmaetanordning foer flytande media enligt ultraljudgaongtidsprincipen.
FI913193A (fi) Magnetisk inspelnings- och aotergivningsanordning.
DE59000095D1 (de) Magnetanker.
DE69013227D1 (de) Magnetkern.
FI915769A0 (fi) Permanent taetning foer paofyllningsbehaollare.
FI904291A0 (fi) Disk med svaengbar frontskiva.
DE69020591T2 (de) Magnetplatteneinheit.
DE59007961D1 (de) Elektromagnetischer drehsteller.
DE3780036T2 (de) Magnetische traegerteilchen.
DE3784245T2 (de) Magnetische traegerteilchen.
DE69003947D1 (de) Magnetventil.
DE69016817D1 (de) Magnetische Eisenoxidteilchen.
DE69017343T2 (de) Magnetischer Toner.
DE59004952D1 (de) Elektromagnetischer drehsteller.
DE69015325D1 (de) Elektromagnetischer vibrator.
DE69131871T2 (de) Magnetische Teilchen
DE59001113D1 (de) Magnetventil.
DE69009912D1 (de) Magnetisches Aufzeichnungsmaterial.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MIRACA HOLDINGS INC., TOKIO/TOKYO, JP

Owner name: NIPPON PAINT CO., LTD., OSAKA, JP

8327 Change in the person/name/address of the patent owner

Owner name: FUJIREBIO INC., TOKIO/TOKYO, JP

Owner name: NIPPON PAINT CO., LTD., OSAKA, JP