DE69034267D1 - Nukleotidsequenzen des Genoms von Retroviren des Typs HIV-1, HIV-2 und SIV und deren Anwendungen, insbesondere zur Amplifikation von Genomen dieser Retroviren und für die In-Vitro-Diagnostik von durch diese Viren ausgelösten Infektionen - Google Patents

Nukleotidsequenzen des Genoms von Retroviren des Typs HIV-1, HIV-2 und SIV und deren Anwendungen, insbesondere zur Amplifikation von Genomen dieser Retroviren und für die In-Vitro-Diagnostik von durch diese Viren ausgelösten Infektionen

Info

Publication number: DE69034267D1
Authority: DE; Germany
Prior art keywords: hiv; gene; nucleic acid; siv; sequence
Prior art date: 1989-06-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69034267T

Other languages

English (en)

Inventor

Maurice Moncany

Luc Montagnier

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Institut Pasteur de Lille

Institut National de la Sante et de la Recherche Medicale INSERM

Original Assignee

Institut Pasteur de Lille

Institut National de la Sante et de la Recherche Medicale INSERM

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-02

Filing date

1990-06-05

Publication date

2010-06-10

1989-06-02 Priority claimed from FR8907354A external-priority patent/FR2647809B1/fr

1989-09-20 Priority claimed from FR8912371A external-priority patent/FR2652091B1/fr

1990-06-05 Application filed by Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut Pasteur de Lille

2010-06-06 Anticipated expiration legal-status Critical

2010-06-10 Application granted granted Critical

2010-06-10 Publication of DE69034267D1 publication Critical patent/DE69034267D1/de

Status Expired - Lifetime legal-status Critical Current

Links

241000713772 Human immunodeficiency virus 1 Species 0.000 title abstract 13
208000031886 HIV Infections Diseases 0.000 title abstract 7
241000713340 Human immunodeficiency virus 2 Species 0.000 title abstract 7
241000700605 Viruses Species 0.000 title abstract 6
230000003321 amplification Effects 0.000 title abstract 2
238000003199 nucleic acid amplification method Methods 0.000 title abstract 2
241001430294 unidentified retrovirus Species 0.000 title 2
108091028043 Nucleic acid sequence Proteins 0.000 title 1
238000003745 diagnosis Methods 0.000 title 1
238000000338 in vitro Methods 0.000 title 1
208000015181 infectious disease Diseases 0.000 title 1
108090000623 proteins and genes Proteins 0.000 abstract 10
108020004707 nucleic acids Proteins 0.000 abstract 8
150000007523 nucleic acids Chemical class 0.000 abstract 8
102000039446 nucleic acids Human genes 0.000 abstract 8
239000013615 primer Substances 0.000 abstract 7
239000012472 biological sample Substances 0.000 abstract 5
230000004544 DNA amplification Effects 0.000 abstract 3
230000015572 biosynthetic process Effects 0.000 abstract 3
238000004925 denaturation Methods 0.000 abstract 3
230000036425 denaturation Effects 0.000 abstract 3
108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 2
102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 2
230000000295 complement effect Effects 0.000 abstract 2
238000001514 detection method Methods 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
235000011178 triphosphate Nutrition 0.000 abstract 2
239000001226 triphosphate Substances 0.000 abstract 2
UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 abstract 2
108020004635 Complementary DNA Proteins 0.000 abstract 1
239000003155 DNA primer Substances 0.000 abstract 1
102100034343 Integrase Human genes 0.000 abstract 1
108091034117 Oligonucleotide Proteins 0.000 abstract 1
108010092799 RNA-directed DNA polymerase Proteins 0.000 abstract 1
238000010804 cDNA synthesis Methods 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000002299 complementary DNA Substances 0.000 abstract 1
238000000605 extraction Methods 0.000 abstract 1
238000009396 hybridization Methods 0.000 abstract 1
239000002777 nucleoside Substances 0.000 abstract 1
125000003835 nucleoside group Chemical group 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
239000000523 sample Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/974—Aids related test
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit

DE69034267T 1989-06-02 1990-06-05 Nukleotidsequenzen des Genoms von Retroviren des Typs HIV-1, HIV-2 und SIV und deren Anwendungen, insbesondere zur Amplifikation von Genomen dieser Retroviren und für die In-Vitro-Diagnostik von durch diese Viren ausgelösten Infektionen Expired - Lifetime DE69034267D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8907354A FR2647809B1 (fr)	1989-06-02	1989-06-02	Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
FR8912371A FR2652091B1 (fr)	1989-09-20	1989-09-20	Sequences nucleotidiques issues du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications notamment pour l'amplification des genomes de ces retrovirus et pour le diagnostic in-vitro des infections dues a ces virus.

Publications (1)

Publication Number	Publication Date
DE69034267D1 true DE69034267D1 (de)	2010-06-10

Family

ID=26227366

Family Applications (7)

Application Number	Title	Priority Date	Filing Date
DE05014676T Pending DE05014676T1 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen von HIV-1, HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von diesen Retroviren und zur In Vitro Diagnostik von diesen Viren verursachten Infektionen
DE69033311T Expired - Lifetime DE69033311T2 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen des Genoms von Retroviren vom Typ HIV-1, HIV-2 und SIV, ihre Verwendungen zur Amplifikation dieser Genome und in-vitro-Diagnose dieser viralen Infektionen
DE69034265T Expired - Lifetime DE69034265D1 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen von HIV-1, HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von pol-Sequenzen dieser Retroviren und zur In Vitro Diagnostik von diesen Viren verursachten Infektionen
DE69034260T Expired - Lifetime DE69034260D1 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen von HIV-1, HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von diesen Retroviren und zur In Vitro Diagnostik von diesen Viren verursachten Infektionen
DE69034220T Expired - Lifetime DE69034220T2 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen von HIV-1, HIV-2 and SIV Retrovirusgenommen, ihre Verwendung zur Amplifizierung von diesen Retrovieren und zur in vitro Diagnostik von diesen Viren verursachten Infektion
DE07025195T Pending DE07025195T1 (de)	1989-06-02	1990-06-05	Nukleotidsequenzen des Genoms von Retroviren des Typs HIV-1, HIV-2 und SIV und deren Anwendungen, insbesondere zur Amplifikation von Genomen dieser Retroviren und für die In-Vitro-Diagnostik von durch diese Viren ausgelösten Infektionen
DE69034267T Expired - Lifetime DE69034267D1 (de)	1989-06-02	1990-06-05	Nukleotidsequenzen des Genoms von Retroviren des Typs HIV-1, HIV-2 und SIV und deren Anwendungen, insbesondere zur Amplifikation von Genomen dieser Retroviren und für die In-Vitro-Diagnostik von durch diese Viren ausgelösten Infektionen

Family Applications Before (6)

Application Number	Title	Priority Date	Filing Date
DE05014676T Pending DE05014676T1 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen von HIV-1, HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von diesen Retroviren und zur In Vitro Diagnostik von diesen Viren verursachten Infektionen
DE69033311T Expired - Lifetime DE69033311T2 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen des Genoms von Retroviren vom Typ HIV-1, HIV-2 und SIV, ihre Verwendungen zur Amplifikation dieser Genome und in-vitro-Diagnose dieser viralen Infektionen
DE69034265T Expired - Lifetime DE69034265D1 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen von HIV-1, HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von pol-Sequenzen dieser Retroviren und zur In Vitro Diagnostik von diesen Viren verursachten Infektionen
DE69034260T Expired - Lifetime DE69034260D1 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen von HIV-1, HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von diesen Retroviren und zur In Vitro Diagnostik von diesen Viren verursachten Infektionen
DE69034220T Expired - Lifetime DE69034220T2 (de)	1989-06-02	1990-06-05	Nukleotid-Sequenzen von HIV-1, HIV-2 and SIV Retrovirusgenommen, ihre Verwendung zur Amplifizierung von diesen Retrovieren und zur in vitro Diagnostik von diesen Viren verursachten Infektion
DE07025195T Pending DE07025195T1 (de)	1989-06-02	1990-06-05	Nukleotidsequenzen des Genoms von Retroviren des Typs HIV-1, HIV-2 und SIV und deren Anwendungen, insbesondere zur Amplifikation von Genomen dieser Retroviren und für die In-Vitro-Diagnostik von durch diese Viren ausgelösten Infektionen

Country Status (12)

Country	Link
US (6)	US5688637A (de)
EP (5)	EP2011888B1 (de)
JP (2)	JP3428012B2 (de)
AT (5)	ATE323183T1 (de)
CA (3)	CA2685262A1 (de)
DE (7)	DE05014676T1 (de)
DK (5)	DK0806484T3 (de)
ES (5)	ES2275451T3 (de)
GR (1)	GR3032261T3 (de)
HK (3)	HK1097574A1 (de)
SG (1)	SG47868A1 (de)
WO (1)	WO1990015066A2 (de)

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1990
- 1990-06-05 DK DK97110543T patent/DK0806484T3/da active
- 1990-06-05 DE DE05014676T patent/DE05014676T1/de active Pending
- 1990-06-05 DE DE69033311T patent/DE69033311T2/de not_active Expired - Lifetime
- 1990-06-05 DE DE69034265T patent/DE69034265D1/de not_active Expired - Lifetime
- 1990-06-05 DE DE69034260T patent/DE69034260D1/de not_active Expired - Lifetime
- 1990-06-05 ES ES05014676T patent/ES2275451T3/es not_active Expired - Lifetime
- 1990-06-05 AT AT97110543T patent/ATE323183T1/de not_active IP Right Cessation
- 1990-06-05 DK DK90401520T patent/DK0403333T3/da active
- 1990-06-05 EP EP07025195A patent/EP2011888B1/de not_active Expired - Lifetime
- 1990-06-05 ES ES07025195T patent/ES2315215T1/es active Pending
- 1990-06-05 EP EP06013029A patent/EP1715064B1/de not_active Expired - Lifetime
- 1990-06-05 AT AT06013029T patent/ATE423856T1/de not_active IP Right Cessation
- 1990-06-05 AT AT90401520T patent/ATE185379T1/de not_active IP Right Cessation
- 1990-06-05 DE DE69034220T patent/DE69034220T2/de not_active Expired - Lifetime
- 1990-06-05 DK DK07025195.4T patent/DK2011888T3/da active
- 1990-06-05 AT AT07025195T patent/ATE466111T1/de not_active IP Right Cessation
- 1990-06-05 JP JP50891190A patent/JP3428012B2/ja not_active Expired - Lifetime
- 1990-06-05 EP EP97110543A patent/EP0806484B1/de not_active Expired - Lifetime
- 1990-06-05 EP EP05014676A patent/EP1642987B1/de not_active Expired - Lifetime
- 1990-06-05 DK DK06013029T patent/DK1715064T3/da active
- 1990-06-05 DE DE07025195T patent/DE07025195T1/de active Pending
- 1990-06-05 ES ES97110543T patent/ES2262166T3/es not_active Expired - Lifetime
- 1990-06-05 AT AT05014676T patent/ATE404699T1/de not_active IP Right Cessation
- 1990-06-05 DK DK05014676T patent/DK1642987T3/da active
- 1990-06-05 CA CA002685262A patent/CA2685262A1/fr not_active Expired - Lifetime
- 1990-06-05 WO PCT/FR1990/000393 patent/WO1990015066A2/fr active Application Filing
- 1990-06-05 EP EP90401520A patent/EP0403333B1/de not_active Expired - Lifetime
- 1990-06-05 ES ES06013029T patent/ES2321326T3/es not_active Expired - Lifetime
- 1990-06-05 CA CA002062829A patent/CA2062829C/fr not_active Expired - Lifetime
- 1990-06-05 ES ES90401520T patent/ES2139567T3/es not_active Expired - Lifetime
- 1990-06-05 CA CA002585164A patent/CA2585164C/fr not_active Expired - Lifetime
- 1990-06-05 DE DE69034267T patent/DE69034267D1/de not_active Expired - Lifetime
- 1990-06-05 SG SG1996004845A patent/SG47868A1/en unknown
1993
- 1993-12-02 US US08/160,465 patent/US5688637A/en not_active Expired - Fee Related
1995
- 1995-06-07 US US08/472,928 patent/US7078516B1/en not_active Expired - Lifetime
1997
- 1997-07-16 US US08/895,231 patent/US5786177A/en not_active Expired - Lifetime
1998
- 1998-06-05 US US09/092,077 patent/US6194142B1/en not_active Expired - Lifetime
1999
- 1999-09-24 JP JP11270165A patent/JP2000093187A/ja active Pending
- 1999-12-28 GR GR990403346T patent/GR3032261T3/el unknown
2004
- 2004-06-08 US US10/862,363 patent/US7759477B2/en not_active Expired - Lifetime
2005
- 2005-08-15 US US11/203,127 patent/US7777020B2/en not_active Expired - Lifetime
2006
- 2006-09-21 HK HK07103317.3A patent/HK1097574A1/xx not_active IP Right Cessation
- 2006-09-21 HK HK09100744.0A patent/HK1125136A1/xx unknown
- 2006-09-21 HK HK06110565.8A patent/HK1092839A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE323183T1 (de)	2006-04-15
DE69034265D1 (de)	2009-04-09
US7078516B1 (en)	2006-07-18
CA2685262A1 (fr)	1990-12-13
CA2062829C (fr)	2007-08-07
DE69034220D1 (de)	2006-05-24
CA2062829A1 (fr)	1990-12-03
US5688637A (en)	1997-11-18
DE69034260D1 (de)	2008-09-25
EP2011888B1 (de)	2010-04-28
EP1715064B1 (de)	2009-02-25
EP0806484B1 (de)	2006-04-12
DE69034220T2 (de)	2006-12-28
EP1642987A3 (de)	2006-08-23
JP3428012B2 (ja)	2003-07-22
DE69033311T2 (de)	2000-02-17
DK0403333T3 (da)	2000-03-20
DK1715064T3 (da)	2009-06-22
EP0403333A3 (de)	1991-11-21
EP0806484A2 (de)	1997-11-12
ES2275451T1 (es)	2007-06-16
HK1097574A1 (en)	2007-06-29
EP1642987B1 (de)	2008-08-13
DE05014676T1 (de)	2007-05-10
ES2315215T1 (es)	2009-04-01
ES2139567T3 (es)	2000-02-16
ES2275451T3 (es)	2009-02-16
US6194142B1 (en)	2001-02-27
CA2585164A1 (fr)	1990-12-13
DK0806484T3 (da)	2006-08-14
DE69033311D1 (de)	1999-11-11
EP1715064A8 (de)	2007-05-16
HK1125136A1 (en)	2009-07-31
EP0403333A2 (de)	1990-12-19
US20060035260A1 (en)	2006-02-16
SG47868A1 (en)	1998-04-17
EP1642987A2 (de)	2006-04-05
EP1715064A1 (de)	2006-10-25
US7777020B2 (en)	2010-08-17
ES2321326T3 (es)	2009-06-04
JPH04507043A (ja)	1992-12-10
WO1990015066A2 (fr)	1990-12-13
EP2011888A1 (de)	2009-01-07
DE07025195T1 (de)	2009-05-07
ATE423856T1 (de)	2009-03-15
ATE466111T1 (de)	2010-05-15
HK1092839A1 (en)	2007-02-16
GR3032261T3 (en)	2000-04-27
EP0806484A3 (de)	2000-09-13
EP0403333B1 (de)	1999-10-06
US20050037340A1 (en)	2005-02-17
WO1990015066A3 (fr)	1991-04-18
JP2000093187A (ja)	2000-04-04
DK1642987T3 (da)	2008-12-01
CA2585164C (fr)	2010-02-02
ATE404699T1 (de)	2008-08-15
US5786177A (en)	1998-07-28
US7759477B2 (en)	2010-07-20
ES2262166T3 (es)	2006-11-16
ATE185379T1 (de)	1999-10-15
DK2011888T3 (da)	2010-08-09

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