DE69107622T2 - Verfahren zur herstellung von (4r-cis)-1,1-dimethylethyl-6-cyanmethyl-2,2-dimethyl-1,3-dioxan-4-acetat. - Google Patents

Verfahren zur herstellung von (4r-cis)-1,1-dimethylethyl-6-cyanmethyl-2,2-dimethyl-1,3-dioxan-4-acetat.

Info

Publication number: DE69107622T2
Authority: DE; Germany
Prior art keywords: dimethylethyl; dioxane; cis; dimethyl; acetate
Prior art date: 1990-10-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69107622T

Other languages

English (en)

Other versions

DE69107622D1 (de

Inventor

Alan Millar

Donald BUTLER

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Warner Lambert Co LLC

Original Assignee

Warner Lambert Co LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-17

Filing date

1991-09-11

Publication date

1995-07-06

1991-09-11 Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC

1995-03-30 Publication of DE69107622D1 publication Critical patent/DE69107622D1/de

1995-07-06 Application granted granted Critical

1995-07-06 Publication of DE69107622T2 publication Critical patent/DE69107622T2/de

2011-09-12 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

DE69107622T 1990-10-17 1991-09-11 Verfahren zur herstellung von (4r-cis)-1,1-dimethylethyl-6-cyanmethyl-2,2-dimethyl-1,3-dioxan-4-acetat. Expired - Fee Related DE69107622T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/599,521 US5103024A (en)	1990-10-17	1990-10-17	Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
PCT/US1991/006697 WO1992006968A1 (en)	1990-10-17	1991-09-11	Process for the synthesis of (4r-cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Publications (2)

Publication Number	Publication Date
DE69107622D1 DE69107622D1 (de)	1995-03-30
DE69107622T2 true DE69107622T2 (de)	1995-07-06

Family

ID=24399962

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69107622T Expired - Fee Related DE69107622T2 (de)	1990-10-17	1991-09-11	Verfahren zur herstellung von (4r-cis)-1,1-dimethylethyl-6-cyanmethyl-2,2-dimethyl-1,3-dioxan-4-acetat.

Country Status (20)

Country	Link
US (1)	US5103024A (de)
EP (1)	EP0553213B1 (de)
JP (1)	JP3105923B2 (de)
KR (1)	KR0166385B1 (de)
AT (1)	ATE118772T1 (de)
AU (1)	AU646311B2 (de)
CA (1)	CA2092997C (de)
CZ (5)	CZ124797A3 (de)
DE (1)	DE69107622T2 (de)
DK (1)	DK0553213T3 (de)
ES (1)	ES2070519T3 (de)
FI (1)	FI108539B (de)
HK (1)	HK1005026A1 (de)
HU (2)	HU213731B (de)
IE (1)	IE62940B1 (de)
NO (1)	NO301588B1 (de)
PT (1)	PT99244B (de)
RU (1)	RU2067580C1 (de)
SK (5)	SK280939B6 (de)
WO (1)	WO1992006968A1 (de)

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HRP960312B1 (en)	1995-07-17	2001-10-31	Warner Lambert Co	NOVEL PROCESS FOR THE PRODUCTION OF AMORPHOUS /R-(R, R)/-2-(4-FLUOROPHENYL)-"beta", "delta"-DIHYDROXY-5-PHENYL-4-/(PHENYLAMINO)CARBONYL/-1H-PYRROLE -1-HEPTANOIC ACID CALCIUM SALT (2 : 1)
US6087511A (en) *	1996-07-16	2000-07-11	Warner-Lambert Company	Process for the production of amorphous [R-(R,R)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl )-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid) calcium salt (2:1)
CA2329893A1 (en) *	1998-04-30	1999-11-11	Kaneka Corporation	Process for producing 6-cyanomethyl-1,3-dioxane-4-acetic acid derivatives
HU227840B1 (en) *	1999-05-06	2012-05-02	Egis Gyogyszergyar Nyilvanosan M Kod Ruszvunytarsasag	Intermediates of atorvastatin synthesis and process for producing them
IN191236B (de)	1999-05-25	2003-10-11	Ranbaxy Lab Ltd
US20040063969A1 (en) *	1999-10-18	2004-04-01	Egis Gyogyszergyar Rt.	Process for the preparation of amorphous atorvastatin calcium
IL149088A0 (en) *	1999-12-17	2002-11-10	Warner Lambert Res & Dev Ie	A process for producing crystalline atorvastatin calcium
ATE309985T1 (de)	1999-12-17	2005-12-15	Pfizer Science & Tech Ltd	Herstellungsverfahren auf industrieller basis von atorvastatin trihydrat hemi-kalziumsalz in kristalliner form
US7300775B2 (en)	1999-12-29	2007-11-27	Verenium Corporation	Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US7521216B2 (en)	1999-12-29	2009-04-21	Verenium Corporation	Nitrilases and methods for making and using them
US20040014195A1 (en) *	1999-12-29	2004-01-22	Diversa Corporation	Nitrilases, nucleic acids encoding them and methods for making and using them
US7608445B1 (en)	1999-12-29	2009-10-27	Verenium Corporation	Nitrilases, nucleic acids encoding them and methods for making and using them
JP3844112B2 (ja)	2000-08-23	2006-11-08	高砂香料工業株式会社	３，５，６−トリヒドロキシヘキサン酸アンモニウム塩誘導体、及びその製造方法
US6476235B2 (en) *	2001-01-09	2002-11-05	Warner-Lambert Company	Process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide
EP1734034A3 (de)	2001-01-09	2007-01-03	Warner-Lambert Company LLC	Carbonsäuresalze von beta-Alaninestern oder -Amiden
WO2002057229A1 (en) *	2001-01-19	2002-07-25	Biocon India Limited	FORM V CRYSTALLINE [R-(R,R)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1- HEPTANOIC ACID HEMI CALCIUM SALT. (ATORVASTATIN)
SI20814A (sl)	2001-01-23	2002-08-31	LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d.	Priprava amorfnega atorvastatina
SI20848A (sl)	2001-03-14	2002-10-31	Lek, Tovarna Farmacevtskih In Kemijskih Izdelkov, D.D.	Farmacevtska formulacija, ki vsebuje atorvastatin kalcij
AP1571A (en) *	2001-06-29	2006-02-10	Warner Lambert Co	Crystalline forms of 'R-(R* ,R*)!-2-(4- fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-'phenylamino)carbonyl!-1H-pyrrole-1-heptanoic acid calcium salt (2:1) (atorvastatin)
GB0116212D0 (en) *	2001-07-03	2001-08-29	Avecia Ltd	Process
PL368647A1 (en)	2001-07-30	2005-04-04	Dr.Reddy's Laboratories Ltd.	Crystalline forms vi and vii of atorvastatin calcium
PE20030324A1 (es) *	2001-07-31	2003-04-03	Warner Lambert Co	Composiciones farmaceuticas de amlodipina y atorvastatina
WO2003018547A2 (en) *	2001-08-31	2003-03-06	Morepen Laboratories Ltd.	An improved process for the preparation of amorphous atorvastatin calcium salt (2:1)
HU227124B1 (en) *	2001-09-14	2010-07-28	Egis Gyogyszergyar Nyilvanosan	Polymorphs of 1-pyrrole derivative, intermediate for the preparation of atorvastatin
UA77990C2 (en) *	2001-12-12	2007-02-15		Crystalline calcium salt of (2:1) [r-(r,r)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrroleheptanic acid
CZ296967B6 (cs) *	2002-02-01	2006-08-16	Zentiva, A.S.	Zpusob výroby amorfní formy hemivápenaté soli (3R,5R) 7-[3-fenyl-4-fenylkarbamoyl-2-(4-fluorfenyl)-5-isopropylpyrrol-1-yl]-3,5-dihydroxyheptanové kyseliny (atorvastatinu)
DE10212492B4 (de) *	2002-03-21	2012-02-02	Daimler Ag	Kolbenpumpe
WO2003106415A2 (en)	2002-06-13	2003-12-24	Diversa Corporation	Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid
JP2005539018A (ja) *	2002-08-06	2005-12-22	ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー	５−（４−フルオロフェニル）−１−［２−（（２ｒ，４ｒ）−４−ヒドロキシ−６−オキソ−テトラヒドロ−ピラン−２−イル）エチル］−２−イソプロピル−４−フェニル−１ｈ−ピロール−３−カルボン酸フェニルアミドの製造方法
JP2006503024A (ja) *	2002-09-03	2006-01-26	モレペン、ラボラトリーズ、リミテッド	Ｖｉ型アトルバスタチンカルシウムまたはその水和物
KR100529703B1 (ko) *	2002-09-23	2005-11-17	임광민	키랄 중간체의 제조방법 및 그를 이용한 아토바스타틴의제조방법
HRP20020885B1 (en) *	2002-11-11	2007-05-31	GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o.	SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
EP1615883A1 (de) *	2003-04-14	2006-01-18	Warner-Lambert Company	Verfahren zur herstellung von 5-(4-fluorophenyl)-1-[2-((2r,4r)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1h-pyrrol-3-carbonsäurephenylamid
US20050182125A1 (en) *	2003-05-16	2005-08-18	Ambit Biosciences Corporation	Pyrrole compounds and uses thereof
US20040248972A1 (en) *	2003-05-16	2004-12-09	Ambit Biosciences Corporation	Compounds and uses thereof
WO2004103959A2 (en) *	2003-05-16	2004-12-02	Ambit Biosciences Corporation	Heterocyclic compounds and uses thereof
US7790197B2 (en) *	2003-06-09	2010-09-07	Warner-Lambert Company Llc	Pharmaceutical compositions of atorvastatin
US20040253305A1 (en) *	2003-06-12	2004-12-16	Luner Paul E.	Pharmaceutical compositions of atorvastatin
US20050271717A1 (en) *	2003-06-12	2005-12-08	Alfred Berchielli	Pharmaceutical compositions of atorvastatin
US7655692B2 (en) *	2003-06-12	2010-02-02	Pfizer Inc.	Process for forming amorphous atorvastatin
AU2004261468B2 (en) *	2003-07-25	2011-04-14	Redx Pharma Plc	Process and intermediate compounds useful in the preparation of statins, particularly atorvastatin
WO2005026116A1 (en) *	2003-09-17	2005-03-24	Warner-Lambert Company Llc	Crystalline forms of `r-(r,r)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-`(phenylamino)carbonyl!-1h-pyrrole-1-heptanoic acid
CA2456430A1 (en) *	2004-01-28	2005-07-28	Brantford Chemicals Inc.	Improved process for the preparation of amorphous atorvastatin calcium
US7994343B2 (en)	2004-03-17	2011-08-09	Ranbaxy Laboratories Limited	Process for the production of atorvastatin calcium in amorphous form
CA2562844A1 (en) *	2004-04-16	2005-10-27	Pfizer Products Inc.	Process for forming amorphous atorvastatin calcium
WO2005105738A2 (en)	2004-05-05	2005-11-10	Pfizer Products Inc.	Salt forms of atorvastatin
US8044086B2 (en) *	2004-07-16	2011-10-25	Lek Pharmaceuticals D.D.	Oxidative degradation products of atorvastatin calcium
CA2701710C (en)	2004-07-20	2013-08-27	Warner-Lambert Company Llc	Novel forms of [r-(r,r)]-2-(4-fluorophenyl)-.beta.,.delta.-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid calcium salt (2:1)
JP2008510798A (ja) *	2004-08-27	2008-04-10	バイオコン・リミテッド	非晶質アトルバスタチンカルシウムのための方法
EP1807055A1 (de)	2004-10-28	2007-07-18	Warner-Lambert Company LLC	Verfahren zur herstellung von amorphem atorvastatin
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CA2589537A1 (en) *	2004-12-02	2006-06-08	Stephen Craig Dyar	Pharmaceutical compositions of amorphous atorvastatin and process for preparing same
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WO2007029217A1 (en) *	2005-09-09	2007-03-15	Pfizer Science And Technology Ireland Limited	Preparation of an atorvastatin intermediate
US20090216029A1 (en) *	2005-09-16	2009-08-27	Yatendra Kumar	Process for the production of atorvastatin calcium in amorphous form
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EP1810667A1 (de)	2006-01-20	2007-07-25	KRKA, tovarna zdravil, d.d., Novo mesto	Pharmazeutische Zusammensetzung enthaltend amorphes Atorvastatin
WO2008053312A2 (en) *	2006-11-02	2008-05-08	Cadila Pharmaceuticals Limited	Process for preparing amorphous atorvastatin hemi calcium salt and its intermediate
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EP2075246A1 (de)	2007-12-27	2009-07-01	M. J. Institute of Research	Verfahren zur Herstellung einer amorphen Form von Atorvastatin-Hemicalcium-Salz
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Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4647576A (en) *	1984-09-24	1987-03-03	Warner-Lambert Company	Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4681893A (en) *	1986-05-30	1987-07-21	Warner-Lambert Company	Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
US5003080A (en) *	1988-02-22	1991-03-26	Warner-Lambert Company	Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
US5093363A (en) *	1989-08-22	1992-03-03	Shionogi & Co., Ltd.	2,4,6-substituted phenol derivatives
DE3929913A1 (de) *	1989-09-08	1991-04-04	Hoechst Ag	4-hydroxytetrahydropyran-2-one sowie die entsprechenden dihydroxycarbonsaeurederivate, salze und ester, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate sowie vorprodukte

1990
- 1990-10-17 US US07/599,521 patent/US5103024A/en not_active Expired - Lifetime
1991
- 1991-09-11 WO PCT/US1991/006697 patent/WO1992006968A1/en active IP Right Grant
- 1991-09-11 SK SK502-98A patent/SK280939B6/sk not_active IP Right Cessation
- 1991-09-11 DE DE69107622T patent/DE69107622T2/de not_active Expired - Fee Related
- 1991-09-11 AU AU88480/91A patent/AU646311B2/en not_active Ceased
- 1991-09-11 SK SK505-98A patent/SK280942B6/sk not_active IP Right Cessation
- 1991-09-11 ES ES91919118T patent/ES2070519T3/es not_active Expired - Lifetime
- 1991-09-11 SK SK503-98A patent/SK280940B6/sk not_active IP Right Cessation
- 1991-09-11 CZ CZ971247A patent/CZ124797A3/cs not_active IP Right Cessation
- 1991-09-11 CZ CZ952094A patent/CZ209495A3/cs not_active IP Right Cessation
- 1991-09-11 SK SK339-93A patent/SK280938B6/sk not_active IP Right Cessation
- 1991-09-11 JP JP03517546A patent/JP3105923B2/ja not_active Expired - Fee Related
- 1991-09-11 CZ CZ971246A patent/CZ124697A3/cs not_active IP Right Cessation
- 1991-09-11 HU HU9301122A patent/HU213731B/hu not_active IP Right Cessation
- 1991-09-11 HU HU9701183A patent/HU219237B/hu not_active IP Right Cessation
- 1991-09-11 EP EP91919118A patent/EP0553213B1/de not_active Expired - Lifetime
- 1991-09-11 DK DK91919118.9T patent/DK0553213T3/da active
- 1991-09-11 CA CA002092997A patent/CA2092997C/en not_active Expired - Fee Related
- 1991-09-11 AT AT91919118T patent/ATE118772T1/de not_active IP Right Cessation
- 1991-09-11 SK SK504-98A patent/SK280941B6/sk not_active IP Right Cessation
- 1991-09-11 CZ CZ971245A patent/CZ282992B6/cs not_active IP Right Cessation
- 1991-09-11 RU RU9193032617A patent/RU2067580C1/ru not_active IP Right Cessation
- 1991-09-11 CZ CZ93614A patent/CZ282922B6/cs not_active IP Right Cessation
- 1991-10-16 PT PT99244A patent/PT99244B/pt not_active IP Right Cessation
1993
- 1993-03-30 IE IE362991A patent/IE62940B1/en not_active IP Right Cessation
- 1993-04-14 FI FI931680A patent/FI108539B/fi active
- 1993-04-16 NO NO931421A patent/NO301588B1/no not_active IP Right Cessation
- 1993-04-16 KR KR1019930701130A patent/KR0166385B1/ko not_active IP Right Cessation
1998
- 1998-05-14 HK HK98104173A patent/HK1005026A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT99244A (pt)	1992-09-30
ATE118772T1 (de)	1995-03-15
AU646311B2 (en)	1994-02-17
PT99244B (pt)	1999-04-30
IE62940B1 (en)	1995-03-08
KR0166385B1 (en)	1999-01-15
CZ282994B6 (cs)	1997-12-17
CZ283003B6 (cs)	1997-12-17
CA2092997A1 (en)	1992-04-18
HK1005026A1 (en)	1998-12-18
SK33993A3 (en)	1993-10-06
HU213731B (en)	1997-09-29
JP3105923B2 (ja)	2000-11-06
WO1992006968A1 (en)	1992-04-30
RU2067580C1 (ru)	1996-10-10
CZ209495A3 (en)	1997-12-17
JPH06502162A (ja)	1994-03-10
SK280938B6 (sk)	2000-09-12
HUT64049A (en)	1993-11-29
FI931680A (fi)	1993-04-14
NO301588B1 (no)	1997-11-17
CZ282993B6 (cs)	1997-12-17
AU8848091A (en)	1992-05-20
SK280941B6 (sk)	2000-09-12
FI108539B (fi)	2002-02-15
HU9701183D0 (en)	1997-09-29
ES2070519T3 (es)	1995-06-01
NO931421D0 (no)	1993-04-16
HU9301122D0 (en)	1993-08-30
FI931680A0 (fi)	1993-04-14
CA2092997C (en)	2002-05-14
CZ124597A3 (en)	1997-12-17
EP0553213B1 (de)	1995-02-22
HU219237B (en)	2001-03-28
IE913629A1 (en)	1992-04-22
CZ124697A3 (en)	1997-12-17
SK280940B6 (sk)	2000-09-12
CZ61493A3 (en)	1994-02-16
DE69107622D1 (de)	1995-03-30
DK0553213T3 (da)	1995-07-17
SK280942B6 (sk)	2000-09-12
KR930702328A (ko)	1993-09-08
NO931421L (no)	1993-06-16
CZ282992B6 (cs)	1997-12-17
CZ124797A3 (en)	1997-12-17
CZ282922B6 (cs)	1997-11-12
EP0553213A1 (de)	1993-08-04
US5103024A (en)	1992-04-07
SK280939B6 (sk)	2000-09-12

Legal Events

Date	Code	Title	Description
1996-03-28	8364	No opposition during term of opposition
2010-07-22	8339	Ceased/non-payment of the annual fee

Publication	Publication Date	Title
DE69107622D1 (de)	1995-03-30	Verfahren zur herstellung von (4r-cis)-1,1-dimethylethyl-6-cyanmethyl-2,2-dimethyl-1,3-dioxan-4-acetat.
ATA242687A (de)	1996-01-15	Verfahren zur herstellung eines antioxidationsmittels, insbesondere zur verwendung als arzneimittel
DE69201959D1 (de)	1995-05-18	Verfahren zur Herstellung von 6,12-Dihydro-6-hydroxy-cannabidiol und dessen Anwendung zur Herstellung von trans-delta-9-Tetrahydrocannabinol.
ATE137493T1 (de)	1996-05-15	Verfahren zur herstellung von zwischenprodukten zur verwendung in der herstellung von alkoxyiminoacetamide
ATE190050T1 (de)	2000-03-15	Verfahren zur herstellung von 2-acetyl-1-pyrrolin in verkapselter form, zwischenprodukte und endprodukt
AT375378B (de)	1984-07-25	Verfahren zur herstellung von 4'-deoxydaunorubicin
ATE117994T1 (de)	1995-02-15	Verfahren zur herstellung von 2-chlor-5- chlormethylpyridin.
DE69415345T2 (de)	1999-05-12	Verfahren zur herstellung von bisnoraldehyden aus bisnoralkohol
DE69014480T2 (de)	1995-04-20	Verfahren zur Herstellung von antikonvulsanten cyclischen Aminosäureverbindungen.
ATE208770T1 (de)	2001-11-15	Verfahren zur herstullung natürlicher 1,3 diol derivate und korrespondierende natürliche 1,3 dioxan derivate
ATA240890A (de)	1996-03-15	Verfahren zur herstellung eines zwischenproduktes von diltiazem
DE69010256T2 (de)	1995-02-23	Verfahren zur Herstellung von L-Ornithin durch Fermentation.
ATE100148T1 (de)	1994-01-15	Verfahren zur herstellung von hochgradig ungesaettigten fettsaeuren.
DE69003957T2 (de)	1994-02-10	Verfahren zur Herstellung von gereinigten, fetten Alkyldiethanolamiden, die daraus hergestellten Produkte und ihre Verwendung.
DE3582345D1 (de)	1991-05-08	Verfahren zur herstellung eines optisch aktiven lactons und neue zwischenprodukte in diesem verfahren.
ATE207139T1 (de)	2001-11-15	Verfahren zur herstellung von butantetracarbonsäure
ATE138903T1 (de)	1996-06-15	Verfahren zur herstellung von substituierten vinylbenzolen
ATE159016T1 (de)	1997-10-15	Verfahren zur herstellung von 5-amino-2,2-dialkyl-1,3-dioxan
DE58906460D1 (de)	1994-01-27	Verfahren zur herstellung von fettalkoholderivaten.
DE3870829D1 (de)	1992-06-11	Enantioselektives verfahren zur herstellung von trans- oder cis-hemicaronaldehyd-derivaten und erhaltene zwischenprodukte.
ATE134993T1 (de)	1996-03-15	Verfahren zur herstellung von cyclopropannitrilderivaten
ATA293888A (de)	1989-12-15	Verfahren zur herstellung eines randflansches sowie nach diesem verfahren hergestellter randflansch
ATE130839T1 (de)	1995-12-15	Verfahren zur herstellung von carboxylierten 2- allylphenolen.
DE3865600D1 (de)	1991-11-21	Enantioselektives verfahren zur herstellung von trans- oder cis-hemicaronaldehyd-derivaten und erhaltende zwischenprodukte.
DE3669158D1 (de)	1990-04-05	Verfahren zur herstellung eines aldehydlaktons.