DE69110467D1 - Vorrichtung zur abgabe von medikamenten. - Google Patents

Vorrichtung zur abgabe von medikamenten.

Info

Publication number
DE69110467D1
DE69110467D1 DE69110467T DE69110467T DE69110467D1 DE 69110467 D1 DE69110467 D1 DE 69110467D1 DE 69110467 T DE69110467 T DE 69110467T DE 69110467 T DE69110467 T DE 69110467T DE 69110467 D1 DE69110467 D1 DE 69110467D1
Authority
DE
Germany
Prior art keywords
drug
tissue
body tissue
passageway
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69110467T
Other languages
English (en)
Other versions
DE69110467T2 (de
Inventor
James Shapland
Mark Knudson
Hin Shimada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CorTrak Medical Inc
Original Assignee
CorTrak Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CorTrak Medical Inc filed Critical CorTrak Medical Inc
Publication of DE69110467D1 publication Critical patent/DE69110467D1/de
Application granted granted Critical
Publication of DE69110467T2 publication Critical patent/DE69110467T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/104—Balloon catheters used for angioplasty
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0475—Tracheal tubes having openings in the tube
    • A61M16/0477—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids
    • A61M16/0481—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids through the cuff wall
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00—Dilators with or without means for introducing media, e.g. remedies
    • A61M29/02—Dilators made of swellable material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems
    • A61N2001/0585—Coronary sinus electrodes
DE69110467T 1990-06-15 1991-06-14 Vorrichtung zur abgabe von medikamenten. Expired - Fee Related DE69110467T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US53896190A 1990-06-15 1990-06-15
US63729991A 1991-01-03 1991-01-03
US70573191A 1991-05-24 1991-05-24
PCT/US1991/004288 WO1991019529A1 (en) 1990-06-15 1991-06-14 Drug delivery apparatus and method

Publications (2)

Publication Number Publication Date
DE69110467D1 true DE69110467D1 (de) 1995-07-20
DE69110467T2 DE69110467T2 (de) 1996-02-01

Family

ID=27415284

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69110467T Expired - Fee Related DE69110467T2 (de) 1990-06-15 1991-06-14 Vorrichtung zur abgabe von medikamenten.

Country Status (8)

Country Link
US (3) US5286254A (de)
EP (1) EP0533816B1 (de)
JP (1) JPH05507226A (de)
AT (1) ATE123658T1 (de)
AU (1) AU8074591A (de)
CA (1) CA2081896A1 (de)
DE (1) DE69110467T2 (de)
WO (1) WO1991019529A1 (de)

Families Citing this family (815)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3915636C1 (de) 1989-05-12 1990-04-26 Sass, Wolfgang, Dr.
US5236413B1 (en) * 1990-05-07 1996-06-18 Andrew J Feiring Method and apparatus for inducing the permeation of medication into internal tissue
EP0533816B1 (de) * 1990-06-15 1995-06-14 Cortrak Medical, Inc. Vorrichtung zur abgabe von medikamenten
US5499971A (en) * 1990-06-15 1996-03-19 Cortrak Medical, Inc. Method for iontophoretically delivering drug adjacent to a heart
US5498238A (en) * 1990-06-15 1996-03-12 Cortrak Medical, Inc. Simultaneous angioplasty and phoretic drug delivery
US6524274B1 (en) 1990-12-28 2003-02-25 Scimed Life Systems, Inc. Triggered release hydrogel drug delivery system
US5893840A (en) * 1991-01-04 1999-04-13 Medtronic, Inc. Releasable microcapsules on balloon catheters
IT1245528B (it) * 1991-05-06 1994-09-29 Mini Ricerca Scient Tecnolog Catetere per angioplastica e metodo per il suo ottenimento.
US5458568A (en) * 1991-05-24 1995-10-17 Cortrak Medical, Inc. Porous balloon for selective dilatation and drug delivery
CA2074304C (en) * 1991-08-02 1996-11-26 Cyril J. Schweich, Jr. Drug delivery catheter
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) * 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5306250A (en) * 1992-04-02 1994-04-26 Indiana University Foundation Method and apparatus for intravascular drug delivery
US6132419A (en) * 1992-05-22 2000-10-17 Genetronics, Inc. Electroporetic gene and drug therapy
US5501662A (en) * 1992-05-22 1996-03-26 Genetronics, Inc. Implantable electroporation method and apparatus for drug and gene delivery
US5507724A (en) * 1992-07-01 1996-04-16 Genetronics, Inc. Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells
AU3321793A (en) * 1992-08-28 1994-03-29 Cortrak Medical, Inc. Internal iontophoresis electrical circuit and waveforms
EP0611311A1 (de) * 1992-08-28 1994-08-24 Cortrak Medical, Inc. Wirkstoff-abgabeeinrichtung mit polymermatrix
JPH0670987A (ja) * 1992-08-28 1994-03-15 Katsuro Tachibana 薬物投与・体液採取ユニット及び装置
US5318014A (en) * 1992-09-14 1994-06-07 Coraje, Inc. Ultrasonic ablation/dissolution transducer
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5634899A (en) * 1993-08-20 1997-06-03 Cortrak Medical, Inc. Simultaneous cardiac pacing and local drug delivery method
US5634901A (en) * 1992-11-02 1997-06-03 Localmed, Inc. Method of using a catheter sleeve
US5336178A (en) * 1992-11-02 1994-08-09 Localmed, Inc. Intravascular catheter with infusion array
US5536250A (en) * 1994-04-01 1996-07-16 Localmed, Inc. Perfusion shunt device and method
US5807306A (en) * 1992-11-09 1998-09-15 Cortrak Medical, Inc. Polymer matrix drug delivery apparatus
US5468223A (en) * 1992-11-30 1995-11-21 C.N.R.S. Paris Electrochemotherapy
US5256141A (en) * 1992-12-22 1993-10-26 Nelson Gencheff Biological material deployment method and apparatus
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) * 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
WO1994021320A1 (en) * 1993-03-15 1994-09-29 Advanced Cardiovascular Systems, Inc. Fluid delivery catheter
US6197789B1 (en) 1995-06-07 2001-03-06 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
US5891459A (en) 1993-06-11 1999-04-06 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
US5861168A (en) * 1993-06-11 1999-01-19 The Board Of Trustees Of The Leland Stanford Junior University Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury
US5852058A (en) * 1993-06-11 1998-12-22 The Board Of Trustees Of The Leland Stanford Junior University Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury
US5994341A (en) * 1993-07-19 1999-11-30 Angiogenesis Technologies, Inc. Anti-angiogenic Compositions and methods for the treatment of arthritis
CN100998869A (zh) * 1993-07-19 2007-07-18 血管技术药物公司 抗血管生长组合物及使用方法
US6025044A (en) * 1993-08-18 2000-02-15 W. L. Gore & Associates, Inc. Thin-wall polytetrafluoroethylene tube
WO1995008289A2 (en) * 1993-09-16 1995-03-30 Scimed Life Systems, Inc. Percutaneous repair of cardiovascular anomalies and repair compositions
US5443495A (en) * 1993-09-17 1995-08-22 Scimed Lifesystems Inc. Polymerization angioplasty balloon implant device
US5421818A (en) * 1993-10-18 1995-06-06 Inner Ear Medical Delivery Systems, Inc. Multi-functional inner ear treatment and diagnostic system
US5792106A (en) * 1993-12-02 1998-08-11 Scimed Life Systems, Inc. In situ stent forming catheter
DE4401227C2 (de) * 1994-01-18 1999-03-18 Ernst Peter Prof Dr M Strecker In den Körper eines Patienten perkutan implantierbare Endoprothese
JP3403233B2 (ja) * 1994-01-20 2003-05-06 テルモ株式会社 バルーンカテーテル
US5647859A (en) * 1994-02-18 1997-07-15 Merit Medical Systems, Inc. Catheter apparatus with means for subcutaneous delivery of anesthetic agent or other fluid medicament
US5533986A (en) * 1994-02-18 1996-07-09 Merit Medical Systems, Inc. Catheter apparatus with means for subcutaneous delivery of anesthetic agent or other fluid medicament
US5772639A (en) * 1994-02-18 1998-06-30 Merit Medical Systems, Inc. Total alimentary nutrition catheter apparatus with means for subcutaneous delivery of anesthetic agent or other fluid medicament
US5797886A (en) * 1994-02-18 1998-08-25 Merit Medical Systems, Inc. Catheter apparatus with means for subcutaneous delivery of anesthetic agent or other fluid medicament
US5817072A (en) * 1994-02-18 1998-10-06 Merit Medical Systems, Inc. Central venous system catheter apparatus with means for subcutaneous delivery of anesthetic agent of other fluid medicament
US5405334A (en) * 1994-02-18 1995-04-11 Merit Medical Systems, Inc. Catheter apparatus with means for subcutaneous delivery of anesthetic agent or other fluid medicament
US5588962A (en) * 1994-03-29 1996-12-31 Boston Scientific Corporation Drug treatment of diseased sites deep within the body
US5562620A (en) * 1994-04-01 1996-10-08 Localmed, Inc. Perfusion shunt device having non-distensible pouch for receiving angioplasty balloon
US5599306A (en) * 1994-04-01 1997-02-04 Localmed, Inc. Method and apparatus for providing external perfusion lumens on balloon catheters
US5486160A (en) * 1994-05-04 1996-01-23 Physion S.R.L. Device and method for the combined electropharmacological treatment of the bladder and the prostatic urethra
US5728068A (en) * 1994-06-14 1998-03-17 Cordis Corporation Multi-purpose balloon catheter
US5505700A (en) * 1994-06-14 1996-04-09 Cordis Corporation Electro-osmotic infusion catheter
US5681278A (en) * 1994-06-23 1997-10-28 Cormedics Corp. Coronary vasculature treatment method
FR2722413B1 (fr) * 1994-07-13 1997-02-07 Marian Devonec Implant therapeutique destine au traitement cytoreducteur selectif de l'obstruction d'une lumiere ou voie naturelle d'un corps humain ou animal
US5817144A (en) * 1994-10-25 1998-10-06 Latis, Inc. Method for contemporaneous application OF laser energy and localized pharmacologic therapy
US5836940A (en) * 1994-10-25 1998-11-17 Latis, Inc. Photoacoustic drug delivery
JPH10510730A (ja) * 1994-12-14 1998-10-20 シメッド ライフ システムズ インコーポレイテッド 原位置ステント形成カテーテル
GB9426379D0 (en) 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
US5891084A (en) * 1994-12-27 1999-04-06 Lee; Vincent W. Multiple chamber catheter delivery system
US5569198A (en) * 1995-01-23 1996-10-29 Cortrak Medical Inc. Microporous catheter
US5749845A (en) * 1995-01-25 1998-05-12 Iotek, Inc. Delivering an agent to an organ
US20030083733A1 (en) * 1997-10-10 2003-05-01 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6176842B1 (en) * 1995-03-08 2001-01-23 Ekos Corporation Ultrasound assembly for use with light activated drugs
US6210356B1 (en) * 1998-08-05 2001-04-03 Ekos Corporation Ultrasound assembly for use with a catheter
US20020091433A1 (en) * 1995-04-19 2002-07-11 Ni Ding Drug release coated stent
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US5665077A (en) * 1995-04-24 1997-09-09 Nitrosci Pharmaceuticals Llc Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis
US7069634B1 (en) 1995-04-28 2006-07-04 Medtronic, Inc. Method for manufacturing a catheter
AU5545596A (en) * 1995-04-28 1996-11-18 Medtronic, Inc. Intraparenchymal infusion catheter system
IE960312A1 (en) 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
US20050131269A1 (en) * 1995-06-07 2005-06-16 Talmadge Karen D. System and method for delivering a therapeutic agent for bone disease
WO1996040171A1 (en) 1995-06-07 1996-12-19 Neuwirth Robert S Intrauterine chemical necrosing method and composition
US6187346B1 (en) 1995-06-07 2001-02-13 Ablation Products, Inc. Intrauterine chemical cauterizing method and composition
US5900433A (en) * 1995-06-23 1999-05-04 Cormedics Corp. Vascular treatment method and apparatus
US5725568A (en) * 1995-06-27 1998-03-10 Scimed Life Systems, Inc. Method and device for recanalizing and grafting arteries
US5713863A (en) * 1996-01-11 1998-02-03 Interventional Technologies Inc. Catheter with fluid medication injectors
US6102904A (en) * 1995-07-10 2000-08-15 Interventional Technologies, Inc. Device for injecting fluid into a wall of a blood vessel
US5746716A (en) * 1995-07-10 1998-05-05 Interventional Technologies Inc. Catheter for injecting fluid medication into an arterial wall
US5873852A (en) * 1995-07-10 1999-02-23 Interventional Technologies Device for injecting fluid into a wall of a blood vessel
US20060271091A1 (en) * 1995-09-18 2006-11-30 Campbell Carey V Balloon catheter device
US5868704A (en) * 1995-09-18 1999-02-09 W. L. Gore & Associates, Inc. Balloon catheter device
US5752934A (en) * 1995-09-18 1998-05-19 W. L. Gore & Associates, Inc. Balloon catheter device
US5735811A (en) * 1995-11-30 1998-04-07 Pharmasonics, Inc. Apparatus and methods for ultrasonically enhanced fluid delivery
US5728062A (en) * 1995-11-30 1998-03-17 Pharmasonics, Inc. Apparatus and methods for vibratory intraluminal therapy employing magnetostrictive transducers
US5725494A (en) * 1995-11-30 1998-03-10 Pharmasonics, Inc. Apparatus and methods for ultrasonically enhanced intraluminal therapy
IL125136A (en) * 1996-01-08 2003-07-31 Impulse Dynamics Nv Electrical cardiac muscle controller method and apparatus
IL125424A0 (en) 1998-07-20 1999-03-12 New Technologies Sa Ysy Ltd Pacing with hemodynamic enhancement
US9289618B1 (en) 1996-01-08 2016-03-22 Impulse Dynamics Nv Electrical muscle controller
US7167748B2 (en) * 1996-01-08 2007-01-23 Impulse Dynamics Nv Electrical muscle controller
US8321013B2 (en) 1996-01-08 2012-11-27 Impulse Dynamics, N.V. Electrical muscle controller and pacing with hemodynamic enhancement
US8825152B2 (en) * 1996-01-08 2014-09-02 Impulse Dynamics, N.V. Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
US9713723B2 (en) 1996-01-11 2017-07-25 Impulse Dynamics Nv Signal delivery through the right ventricular septum
DE19654895C2 (de) * 1996-02-07 2000-07-27 Sanol Arznei Schwarz Gmbh Detektionsverfahren
US6053900A (en) * 1996-02-16 2000-04-25 Brown; Joe E. Apparatus and method for delivering diagnostic and therapeutic agents intravascularly
US5823996A (en) * 1996-02-29 1998-10-20 Cordis Corporation Infusion balloon catheter
US5733269A (en) * 1996-03-15 1998-03-31 Fuisz Technologies Ltd. Method and kit for positioning transdermal delivery system
WO1997036630A1 (en) * 1996-03-29 1997-10-09 Iotek, Inc. Urinary catheter
US6110155A (en) * 1996-04-30 2000-08-29 Medtronic, Inc. Anti-inflammatory-agent-loaded catheter and method for preventing tissue fibrosis
US6171298B1 (en) 1996-05-03 2001-01-09 Situs Corporation Intravesical infuser
US6077257A (en) * 1996-05-06 2000-06-20 Vidacare, Inc. Ablation of rectal and other internal body structures
US5921954A (en) * 1996-07-10 1999-07-13 Mohr, Jr.; Lawrence G. Treating aneurysms by applying hardening/softening agents to hardenable/softenable substances
US7022105B1 (en) * 1996-05-06 2006-04-04 Novasys Medical Inc. Treatment of tissue in sphincters, sinuses and orifices
US5916194A (en) * 1996-05-24 1999-06-29 Sarcos, Inc. Catheter/guide wire steering apparatus and method
EP1616563A3 (de) 1996-05-24 2006-01-25 Angiotech Pharmaceuticals, Inc. Perivaskuläre Verabreichung anti-angiogener Faktoren zur Behandlung oder Prävention von Gefässerkrankungen
US5925519A (en) * 1996-06-03 1999-07-20 The Regents Of The University Of California Genetic alterations associated with prostate cancer
US20070161968A1 (en) * 1996-06-04 2007-07-12 Vance Products Inc., Dba Cood Urological Inc. Implantable medical device with pharmacologically active ingredient
US20060025726A1 (en) * 1996-06-04 2006-02-02 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with pharmacologically active layer
US20070161967A1 (en) * 1996-06-04 2007-07-12 Vance Products Inc., Dba Cook Urological Inc. Implantable medical device with pharmacologically active ingredient
ITFI960154A1 (it) * 1996-06-27 1997-12-29 Giglio Mauro Del Metodo e sistema per la terapia delle aritmie ipercinetiche atriali
CA2211249C (en) * 1996-07-24 2007-07-17 Cordis Corporation Balloon catheter and methods of use
US5709653A (en) * 1996-07-25 1998-01-20 Cordis Corporation Photodynamic therapy balloon catheter with microporous membrane
US5797868A (en) * 1996-07-25 1998-08-25 Cordis Corporation Photodynamic therapy balloon catheter
US5720775A (en) * 1996-07-31 1998-02-24 Cordis Corporation Percutaneous atrial line ablation catheter
US7908003B1 (en) 1996-08-19 2011-03-15 Mr3 Medical Llc System and method for treating ischemia by improving cardiac efficiency
US7840264B1 (en) 1996-08-19 2010-11-23 Mr3 Medical, Llc System and method for breaking reentry circuits by cooling cardiac tissue
US20030093143A1 (en) * 1999-03-01 2003-05-15 Yiju Zhao Medical device having surface depressions containing nitric oxide releasing compound
US6057367A (en) 1996-08-30 2000-05-02 Duke University Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
US6464660B2 (en) 1996-09-05 2002-10-15 Pharmasonics, Inc. Balloon catheters having ultrasonically driven interface surfaces and methods for their use
US5846218A (en) * 1996-09-05 1998-12-08 Pharmasonics, Inc. Balloon catheters having ultrasonically driven interface surfaces and methods for their use
US8353908B2 (en) 1996-09-20 2013-01-15 Novasys Medical, Inc. Treatment of tissue in sphincters, sinuses, and orifices
EP0835673A3 (de) 1996-10-10 1998-09-23 Schneider (Usa) Inc. Katheter für Gewebedilatation und Arzneimittelverabreichung
US5704908A (en) * 1996-10-10 1998-01-06 Genetronics, Inc. Electroporation and iontophoresis catheter with porous balloon
US6024717A (en) * 1996-10-24 2000-02-15 Vibrx, Inc. Apparatus and method for sonically enhanced drug delivery
US5904651A (en) * 1996-10-28 1999-05-18 Ep Technologies, Inc. Systems and methods for visualizing tissue during diagnostic or therapeutic procedures
US5845646A (en) * 1996-11-05 1998-12-08 Lemelson; Jerome System and method for treating select tissue in a living being
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
US6221038B1 (en) 1996-11-27 2001-04-24 Pharmasonics, Inc. Apparatus and methods for vibratory intraluminal therapy employing magnetostrictive transducers
US6293924B1 (en) * 1996-12-12 2001-09-25 Advanced Cardiovascular Systems, Inc. Balloon assembly with separately inflatable sections
US6018679A (en) * 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
US6338726B1 (en) 1997-02-06 2002-01-15 Vidacare, Inc. Treating urinary and other body strictures
ES2388248T3 (es) 1997-03-31 2012-10-11 Boston Scientific Scimed Limited Forma de dosificación que comprende taxol en forma cristalina
US6776792B1 (en) * 1997-04-24 2004-08-17 Advanced Cardiovascular Systems Inc. Coated endovascular stent
US6582392B1 (en) * 1998-05-01 2003-06-24 Ekos Corporation Ultrasound assembly for use with a catheter
US6676626B1 (en) * 1998-05-01 2004-01-13 Ekos Corporation Ultrasound assembly with increased efficacy
WO1998048711A1 (en) * 1997-05-01 1998-11-05 Ekos Corporation Ultrasound catheter
US6723063B1 (en) * 1998-06-29 2004-04-20 Ekos Corporation Sheath for use with an ultrasound element
US5976120A (en) * 1997-05-05 1999-11-02 Micro Therapeutics, Inc. Single segment microcatheter
US5891457A (en) * 1997-05-12 1999-04-06 Neuwirth; Robert S. Intrauterine chemical necrosing method, composition, and apparatus
US6272370B1 (en) 1998-08-07 2001-08-07 The Regents Of University Of Minnesota MR-visible medical device for neurological interventions using nonlinear magnetic stereotaxis and a method imaging
US7048716B1 (en) 1997-05-15 2006-05-23 Stanford University MR-compatible devices
US6228046B1 (en) 1997-06-02 2001-05-08 Pharmasonics, Inc. Catheters comprising a plurality of oscillators and methods for their use
US5931805A (en) * 1997-06-02 1999-08-03 Pharmasonics, Inc. Catheters comprising bending transducers and methods for their use
US6045528A (en) * 1997-06-13 2000-04-04 Intraear, Inc. Inner ear fluid transfer and diagnostic system
JP4441000B2 (ja) * 1997-06-23 2010-03-24 克郎 立花 生体組織処理装置
HUP0004589A3 (en) 1997-06-30 2003-08-28 Centre Nat Rech Scient Improved method for transferring nucleic acid into the striped muscle and combination therefor
CN1261808A (zh) 1997-06-30 2000-08-02 罗纳-布朗克罗莱尔股份有限公司 向多细胞真核生物的细胞中转移核酸的改进方法和用于实施该方法的组合
US6994851B1 (en) 1997-07-10 2006-02-07 Mannkind Corporation Method of inducing a CTL response
US6977074B2 (en) * 1997-07-10 2005-12-20 Mannkind Corporation Method of inducing a CTL response
US6123725A (en) * 1997-07-11 2000-09-26 A-Med Systems, Inc. Single port cardiac support apparatus
US7182727B2 (en) * 1997-07-11 2007-02-27 A—Med Systems Inc. Single port cardiac support apparatus
US6056721A (en) * 1997-08-08 2000-05-02 Sunscope International, Inc. Balloon catheter and method
US9023031B2 (en) * 1997-08-13 2015-05-05 Verathon Inc. Noninvasive devices, methods, and systems for modifying tissues
CA2301545A1 (en) 1997-08-22 1999-03-04 Vincent Decrescito An apparatus for preventing loss of a composition during a medical procedure
US5999847A (en) * 1997-10-21 1999-12-07 Elstrom; John A. Apparatus and method for delivery of surgical and therapeutic agents
US20020055731A1 (en) * 1997-10-24 2002-05-09 Anthony Atala Methods for promoting cell transfection in vivo
US6485514B1 (en) 1997-12-12 2002-11-26 Supergen, Inc. Local delivery of therapeutic agents
US7066884B2 (en) * 1998-01-08 2006-06-27 Sontra Medical, Inc. System, method, and device for non-invasive body fluid sampling and analysis
US8287483B2 (en) * 1998-01-08 2012-10-16 Echo Therapeutics, Inc. Method and apparatus for enhancement of transdermal transport
US20060015058A1 (en) * 1998-01-08 2006-01-19 Kellogg Scott C Agents and methods for enhancement of transdermal transport
US9586023B2 (en) 1998-02-06 2017-03-07 Boston Scientific Limited Direct stream hydrodynamic catheter system
WO2009117663A2 (en) 2008-03-20 2009-09-24 Medrad, Inc. Direct stream hydrodynamic catheter system
US20100114087A1 (en) * 1998-02-19 2010-05-06 Edwards Stuart D Methods and devices for treating urinary incontinence
US6096726A (en) 1998-03-11 2000-08-01 Surface Solutions Laboratories Incorporated Multicomponent complex for use with substrate
US7208011B2 (en) * 2001-08-20 2007-04-24 Conor Medsystems, Inc. Implantable medical device with drug filled holes
US20040254635A1 (en) * 1998-03-30 2004-12-16 Shanley John F. Expandable medical device for delivery of beneficial agent
US6241762B1 (en) * 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6219577B1 (en) 1998-04-14 2001-04-17 Global Vascular Concepts, Inc. Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
US6419643B1 (en) 1998-04-21 2002-07-16 Alsius Corporation Central venous catheter with heat exchange properties
US6171296B1 (en) 1998-04-28 2001-01-09 Microtherapeutics, Inc. Flow directed catheter
US6267747B1 (en) 1998-05-11 2001-07-31 Cardeon Corporation Aortic catheter with porous aortic root balloon and methods for inducing cardioplegic arrest
US6463317B1 (en) 1998-05-19 2002-10-08 Regents Of The University Of Minnesota Device and method for the endovascular treatment of aneurysms
AU756562B2 (en) 1998-05-21 2003-01-16 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Method for pressure mediated selective delivery of therapeutic substances and cannula
AU4435399A (en) 1998-06-11 1999-12-30 Cerus Corporation Inhibiting proliferation of arterial smooth muscle cells
US6440102B1 (en) 1998-07-23 2002-08-27 Durect Corporation Fluid transfer and diagnostic system for treating the inner ear
AU5333599A (en) * 1998-08-06 2000-02-28 Cardeon Corporation Aortic catheter with porous aortic arch balloon and methods for selective aorticperfusion
WO2000010552A2 (en) * 1998-08-24 2000-03-02 Global Vascular Concepts, Inc. Use of anti-angiogenic agents for inhibiting vessel wall injury
AU5757299A (en) * 1998-09-21 2000-04-10 Elan Corporation, Plc Method and system for enhancing delivery of an agent
US6312402B1 (en) 1998-09-24 2001-11-06 Ekos Corporation Ultrasound catheter for improving blood flow to the heart
US6135976A (en) * 1998-09-25 2000-10-24 Ekos Corporation Method, device and kit for performing gene therapy
US6293967B1 (en) 1998-10-29 2001-09-25 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US20040171980A1 (en) 1998-12-18 2004-09-02 Sontra Medical, Inc. Method and apparatus for enhancement of transdermal transport
US6210392B1 (en) 1999-01-15 2001-04-03 Interventional Technologies, Inc. Method for treating a wall of a blood vessel
US6695830B2 (en) * 1999-01-15 2004-02-24 Scimed Life Systems, Inc. Method for delivering medication into an arterial wall for prevention of restenosis
US7572245B2 (en) * 2003-09-15 2009-08-11 Atrium Medical Corporation Application of a therapeutic substance to a tissue location using an expandable medical device
US7947015B2 (en) * 1999-01-25 2011-05-24 Atrium Medical Corporation Application of a therapeutic substance to a tissue location using an expandable medical device
US6395208B1 (en) 1999-01-25 2002-05-28 Atrium Medical Corporation Method of making an expandable fluoropolymer device
US6955661B1 (en) 1999-01-25 2005-10-18 Atrium Medical Corporation Expandable fluoropolymer device for delivery of therapeutic agents and method of making
US7637886B2 (en) * 1999-01-25 2009-12-29 Atrium Medical Corporation Expandable fluoropolymer device and method of making
EP2208782B1 (de) * 1999-02-04 2017-05-31 Pluristem Ltd. Verfahren und Vorrichtung zur Haltung und Expansion von hematopoietischen Stammzellen und/oder Vorläuferzellen
US8700161B2 (en) * 1999-03-05 2014-04-15 Metacure Limited Blood glucose level control
US20040249421A1 (en) * 2000-09-13 2004-12-09 Impulse Dynamics Nv Blood glucose level control
US8666495B2 (en) * 1999-03-05 2014-03-04 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US8346363B2 (en) * 1999-03-05 2013-01-01 Metacure Limited Blood glucose level control
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US8019421B2 (en) * 1999-03-05 2011-09-13 Metacure Limited Blood glucose level control
US6200257B1 (en) 1999-03-24 2001-03-13 Proxima Therapeutics, Inc. Catheter with permeable hydrogel membrane
US6290673B1 (en) 1999-05-20 2001-09-18 Conor Medsystems, Inc. Expandable medical device delivery system and method
US7190997B1 (en) 1999-06-04 2007-03-13 Impulse Dynamics Nv Drug delivery device
US7171263B2 (en) * 1999-06-04 2007-01-30 Impulse Dynamics Nv Drug delivery device
US7092753B2 (en) * 1999-06-04 2006-08-15 Impulse Dynamics Nv Drug delivery device
AU4947100A (en) 1999-06-04 2000-12-28 Impulse Dynamics N.V. Drug delivery device
CA2376375C (en) * 1999-06-05 2011-07-12 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for inhibiting cardiovascular cell proliferation
US6488658B1 (en) 1999-06-29 2002-12-03 Ethicon Endo-Surgery, Inc. Method of treating the inner lining of an organ using a bipolar electrosurgical instrument including a plurality of balloon electrodes
US6238392B1 (en) 1999-06-29 2001-05-29 Ethicon Endo-Surgery, Inc. Bipolar electrosurgical instrument including a plurality of balloon electrodes
US6494862B1 (en) * 1999-07-13 2002-12-17 Advanced Cardiovascular Systems, Inc. Substance delivery apparatus and a method of delivering a therapeutic substance to an anatomical passageway
US6283947B1 (en) 1999-07-13 2001-09-04 Advanced Cardiovascular Systems, Inc. Local drug delivery injection catheter
US7892201B1 (en) 1999-08-27 2011-02-22 Gore Enterprise Holdings, Inc. Balloon catheter and method of mounting same
US20040029952A1 (en) * 1999-09-03 2004-02-12 Yung-Ming Chen Ethylene vinyl alcohol composition and coating
US7682647B2 (en) * 1999-09-03 2010-03-23 Advanced Cardiovascular Systems, Inc. Thermal treatment of a drug eluting implantable medical device
US6759054B2 (en) 1999-09-03 2004-07-06 Advanced Cardiovascular Systems, Inc. Ethylene vinyl alcohol composition and coating
US6503954B1 (en) * 2000-03-31 2003-01-07 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing actinomycin D and a method of forming the same
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US7807211B2 (en) 1999-09-03 2010-10-05 Advanced Cardiovascular Systems, Inc. Thermal treatment of an implantable medical device
US6503556B2 (en) 2000-12-28 2003-01-07 Advanced Cardiovascular Systems, Inc. Methods of forming a coating for a prosthesis
US6749626B1 (en) 2000-03-31 2004-06-15 Advanced Cardiovascular Systems, Inc. Actinomycin D for the treatment of vascular disease
US20070032853A1 (en) * 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
US6713119B2 (en) 1999-09-03 2004-03-30 Advanced Cardiovascular Systems, Inc. Biocompatible coating for a prosthesis and a method of forming the same
US6682545B1 (en) 1999-10-06 2004-01-27 The Penn State Research Foundation System and device for preventing restenosis in body vessels
US6420378B1 (en) 1999-10-15 2002-07-16 Supergen, Inc. Inhibition of abnormal cell proliferation with camptothecin and combinations including the same
US6738661B1 (en) 1999-10-22 2004-05-18 Biosynergetics, Inc. Apparatus and methods for the controllable modification of compound concentration in a tube
AU1049901A (en) 1999-10-25 2001-05-08 Impulse Dynamics N.V. Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof
US6993385B1 (en) * 1999-10-25 2006-01-31 Impulse Dynamics N.V. Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof
CA2387127A1 (en) 1999-10-25 2001-05-17 Therus Corporation Use of focused ultrasound for vascular sealing
US7027863B1 (en) 1999-10-25 2006-04-11 Impulse Dynamics N.V. Device for cardiac therapy
US6626855B1 (en) * 1999-11-26 2003-09-30 Therus Corpoation Controlled high efficiency lesion formation using high intensity ultrasound
US6206852B1 (en) 1999-12-15 2001-03-27 Advanced Cardiovascular Systems, Inc. Balloon catheter having a small profile catheter
US6908624B2 (en) * 1999-12-23 2005-06-21 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
AU2599501A (en) * 1999-12-29 2001-07-09 Advanced Cardiovascular Systems Inc. Device and active component for inhibiting formation of thrombus-inflammatory cell matrix
US7166098B1 (en) * 1999-12-30 2007-01-23 Advanced Cardiovascular Systems, Inc. Medical assembly with transducer for local delivery of a therapeutic substance and method of using same
US6663622B1 (en) * 2000-02-11 2003-12-16 Iotek, Inc. Surgical devices and methods for use in tissue ablation procedures
US6641604B1 (en) 2000-02-11 2003-11-04 Iotek, Inc. Devices and method for manipulation of organ tissue
US6558314B1 (en) 2000-02-11 2003-05-06 Iotek, Inc. Devices and method for manipulation of organ tissue
US6613082B2 (en) 2000-03-13 2003-09-02 Jun Yang Stent having cover with drug delivery capability
US6379382B1 (en) 2000-03-13 2002-04-30 Jun Yang Stent having cover with drug delivery capability
US7201770B2 (en) * 2000-03-21 2007-04-10 Cordis Corporation Everting balloon stent delivery system having tapered leading edge
US6818247B1 (en) 2000-03-31 2004-11-16 Advanced Cardiovascular Systems, Inc. Ethylene vinyl alcohol-dimethyl acetamide composition and a method of coating a stent
AU2001241974A1 (en) * 2000-03-31 2001-10-15 Advanced Cardiovascular Systems Inc. Actinomycin d for the treatment of vascular disease
US7682648B1 (en) 2000-05-31 2010-03-23 Advanced Cardiovascular Systems, Inc. Methods for forming polymeric coatings on stents
CA2410632A1 (en) 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
US20040158317A1 (en) * 2000-07-18 2004-08-12 Pharmasonics, Inc. Coated stent with ultrasound therapy
US20050113798A1 (en) * 2000-07-21 2005-05-26 Slater Charles R. Methods and apparatus for treating the interior of a blood vessel
US20030120256A1 (en) * 2001-07-03 2003-06-26 Syntheon, Llc Methods and apparatus for sclerosing the wall of a varicose vein
US20050107738A1 (en) * 2000-07-21 2005-05-19 Slater Charles R. Occludable intravascular catheter for drug delivery and method of using the same
US6464662B1 (en) 2000-07-26 2002-10-15 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
US6451373B1 (en) * 2000-08-04 2002-09-17 Advanced Cardiovascular Systems, Inc. Method of forming a therapeutic coating onto a surface of an implantable prosthesis
AU2001288388A1 (en) * 2000-08-24 2002-03-04 Encapsulation Systems, Inc. Substance delivery system
US6544221B1 (en) * 2000-08-30 2003-04-08 Advanced Cardiovascular Systems, Inc. Balloon designs for drug delivery
US6716444B1 (en) 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
US6953560B1 (en) 2000-09-28 2005-10-11 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
US7306591B2 (en) 2000-10-02 2007-12-11 Novasys Medical, Inc. Apparatus and methods for treating female urinary incontinence
US6764507B2 (en) 2000-10-16 2004-07-20 Conor Medsystems, Inc. Expandable medical device with improved spatial distribution
AU9463401A (en) 2000-10-16 2002-04-29 Conor Medsystems Inc Expandable medical device for delivery of beneficial agent
US6783793B1 (en) * 2000-10-26 2004-08-31 Advanced Cardiovascular Systems, Inc. Selective coating of medical devices
US6833153B1 (en) 2000-10-31 2004-12-21 Advanced Cardiovascular Systems, Inc. Hemocompatible coatings on hydrophobic porous polymers
US7803149B2 (en) * 2002-07-12 2010-09-28 Cook Incorporated Coated medical device
US7807210B1 (en) 2000-10-31 2010-10-05 Advanced Cardiovascular Systems, Inc. Hemocompatible polymers on hydrophobic porous polymers
US6547767B1 (en) 2000-11-14 2003-04-15 Advanced Cardiovascular Systems, Inc. Syringe assembly for a catheter
US6591133B1 (en) 2000-11-27 2003-07-08 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
US7083642B2 (en) * 2000-12-22 2006-08-01 Avantec Vascular Corporation Delivery of therapeutic capable agents
US20030050692A1 (en) * 2000-12-22 2003-03-13 Avantec Vascular Corporation Delivery of therapeutic capable agents
US7077859B2 (en) 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
US20050203612A1 (en) * 2000-12-22 2005-09-15 Avantec Vascular Corporation Devices delivering therapeutic agents and methods regarding the same
US20050125054A1 (en) * 2000-12-22 2005-06-09 Avantec Vascular Corporation Devices delivering therapeutic agents and methods regarding the same
JP2004523275A (ja) * 2000-12-22 2004-08-05 アバンテク バスキュラー コーポレーション 治療能力のある薬剤の送達
US6939375B2 (en) 2000-12-22 2005-09-06 Avantac Vascular Corporation Apparatus and methods for controlled substance delivery from implanted prostheses
US7018405B2 (en) 2000-12-22 2006-03-28 Avantec Vascular Corporation Intravascular delivery of methylprednisolone
US6471980B2 (en) 2000-12-22 2002-10-29 Avantec Vascular Corporation Intravascular delivery of mycophenolic acid
US20020082679A1 (en) * 2000-12-22 2002-06-27 Avantec Vascular Corporation Delivery or therapeutic capable agents
US20020082678A1 (en) * 2000-12-22 2002-06-27 Motasim Sirhan Intravascular delivery of mizoribine
US20030033007A1 (en) * 2000-12-22 2003-02-13 Avantec Vascular Corporation Methods and devices for delivery of therapeutic capable agents with variable release profile
US6824559B2 (en) 2000-12-22 2004-11-30 Advanced Cardiovascular Systems, Inc. Ethylene-carboxyl copolymers as drug delivery matrices
US6663662B2 (en) 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
US6540776B2 (en) 2000-12-28 2003-04-01 Advanced Cardiovascular Systems, Inc. Sheath for a prosthesis and methods of forming the same
US7504125B1 (en) 2001-04-27 2009-03-17 Advanced Cardiovascular Systems, Inc. System and method for coating implantable devices
US8277868B2 (en) * 2001-01-05 2012-10-02 Abbott Cardiovascular Systems Inc. Balloon catheter for delivering therapeutic agents
US6544223B1 (en) * 2001-01-05 2003-04-08 Advanced Cardiovascular Systems, Inc. Balloon catheter for delivering therapeutic agents
US7179251B2 (en) * 2001-01-17 2007-02-20 Boston Scientific Scimed, Inc. Therapeutic delivery balloon
WO2002058606A1 (en) * 2001-01-24 2002-08-01 Alsius Corporation Central venous catheter with heat exchange properties
US6964680B2 (en) * 2001-02-05 2005-11-15 Conor Medsystems, Inc. Expandable medical device with tapered hinge
US20040073294A1 (en) 2002-09-20 2004-04-15 Conor Medsystems, Inc. Method and apparatus for loading a beneficial agent into an expandable medical device
DE10105592A1 (de) * 2001-02-06 2002-08-08 Achim Goepferich Platzhalter zur Arzneistofffreigabe in der Stirnhöhle
EP1258230A3 (de) * 2001-03-29 2003-12-10 CardioSafe Ltd Ballonkathetervorrichtung
US6645135B1 (en) * 2001-03-30 2003-11-11 Advanced Cardiovascular Systems, Inc. Intravascular catheter device and method for simultaneous local delivery of radiation and a therapeutic substance
US6780424B2 (en) 2001-03-30 2004-08-24 Charles David Claude Controlled morphologies in polymer drug for release of drugs from polymer films
US6764505B1 (en) 2001-04-12 2004-07-20 Advanced Cardiovascular Systems, Inc. Variable surface area stent
US6817986B2 (en) 2001-04-13 2004-11-16 Avant Medical Corp. Jet injector with data logging system for use in compliance and dose monitoring programs
US6712845B2 (en) * 2001-04-24 2004-03-30 Advanced Cardiovascular Systems, Inc. Coating for a stent and a method of forming the same
US6613083B2 (en) * 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US6537195B2 (en) 2001-05-07 2003-03-25 Xoft, Microtube, Inc. Combination x-ray radiation and drug delivery devices and methods for inhibiting hyperplasia
US7018371B2 (en) * 2001-05-07 2006-03-28 Xoft, Inc. Combination ionizing radiation and radiosensitizer delivery devices and methods for inhibiting hyperplasia
US6656506B1 (en) * 2001-05-09 2003-12-02 Advanced Cardiovascular Systems, Inc. Microparticle coated medical device
US7651695B2 (en) 2001-05-18 2010-01-26 Advanced Cardiovascular Systems, Inc. Medicated stents for the treatment of vascular disease
US6981964B2 (en) * 2001-05-22 2006-01-03 Boston Scientific Scimed, Inc. Draining bodily fluids with a stent
US6743462B1 (en) * 2001-05-31 2004-06-01 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating implantable devices
US7862495B2 (en) * 2001-05-31 2011-01-04 Advanced Cardiovascular Systems, Inc. Radiation or drug delivery source with activity gradient to minimize edge effects
US8741378B1 (en) 2001-06-27 2014-06-03 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device
US6695920B1 (en) 2001-06-27 2004-02-24 Advanced Cardiovascular Systems, Inc. Mandrel for supporting a stent and a method of using the mandrel to coat a stent
US6565659B1 (en) * 2001-06-28 2003-05-20 Advanced Cardiovascular Systems, Inc. Stent mounting assembly and a method of using the same to coat a stent
US6656216B1 (en) * 2001-06-29 2003-12-02 Advanced Cardiovascular Systems, Inc. Composite stent with regioselective material
WO2003009778A2 (en) * 2001-07-26 2003-02-06 Avantec Vascular Corporation Methods and devices for delivery of therapeutic capable agents with variable release profile
US7682669B1 (en) 2001-07-30 2010-03-23 Advanced Cardiovascular Systems, Inc. Methods for covalently immobilizing anti-thrombogenic material into a coating on a medical device
US7056338B2 (en) 2003-03-28 2006-06-06 Conor Medsystems, Inc. Therapeutic agent delivery device with controlled therapeutic agent release rates
US6908448B2 (en) * 2001-08-24 2005-06-21 Dermisonics, Inc. Substance delivery device
US20050075599A1 (en) * 2001-08-24 2005-04-07 Redding Bruce K. Ultrasonically enhanced saline treatment for burn damaged skin
US20040137066A1 (en) * 2001-11-26 2004-07-15 Swaminathan Jayaraman Rationally designed therapeutic intravascular implant coating
US6641611B2 (en) 2001-11-26 2003-11-04 Swaminathan Jayaraman Therapeutic coating for an intravascular implant
US8303651B1 (en) 2001-09-07 2012-11-06 Advanced Cardiovascular Systems, Inc. Polymeric coating for reducing the rate of release of a therapeutic substance from a stent
US7285304B1 (en) 2003-06-25 2007-10-23 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US7989018B2 (en) 2001-09-17 2011-08-02 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US6790223B2 (en) 2001-09-21 2004-09-14 Scimed Life Systems, Inc. Delivering a uretheral stent
US6753071B1 (en) 2001-09-27 2004-06-22 Advanced Cardiovascular Systems, Inc. Rate-reducing membrane for release of an agent
US7223282B1 (en) * 2001-09-27 2007-05-29 Advanced Cardiovascular Systems, Inc. Remote activation of an implantable device
US7349733B2 (en) * 2001-11-02 2008-03-25 Ceramatel, Inc. Iontophoretic drug delivery systems
US20040019318A1 (en) * 2001-11-07 2004-01-29 Wilson Richard R. Ultrasound assembly for use with a catheter
US6517889B1 (en) * 2001-11-26 2003-02-11 Swaminathan Jayaraman Process for coating a surface of a stent
US7488313B2 (en) * 2001-11-29 2009-02-10 Boston Scientific Scimed, Inc. Mechanical apparatus and method for dilating and delivering a therapeutic agent to a site of treatment
US7175874B1 (en) 2001-11-30 2007-02-13 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating implantable devices
US6663880B1 (en) 2001-11-30 2003-12-16 Advanced Cardiovascular Systems, Inc. Permeabilizing reagents to increase drug delivery and a method of local delivery
AU2002359576A1 (en) 2001-12-03 2003-06-17 Ekos Corporation Catheter with multiple ultrasound radiating members
DE60213457T2 (de) * 2001-12-03 2007-10-18 Ekos Corp., Bothell Ultraschallkatheter für kleine gefässe
US6709514B1 (en) * 2001-12-28 2004-03-23 Advanced Cardiovascular Systems, Inc. Rotary coating apparatus for coating implantable medical devices
EP1467658A1 (de) * 2002-01-23 2004-10-20 Iotek, Inc. Vorrichtungen zum halten eines körperorgans
US20050267407A1 (en) * 2002-02-01 2005-12-01 Vascular Designs, Inc. Multi-function catheter and use thereof
US20030220297A1 (en) 2002-02-01 2003-11-27 Berstein David L. Phosphorus-containing compounds and uses thereof
US8062251B2 (en) * 2002-02-01 2011-11-22 Vascular Designs, Inc. Multi-function catheter and use thereof
CA2476263C (en) * 2002-02-01 2012-08-21 Robert J. Goldman Multi-function catheter and use thereof
US6775570B2 (en) 2002-02-04 2004-08-10 Ceramatec, Inc. Iontophoretic treatment device
US7047069B2 (en) 2002-02-04 2006-05-16 Ceramatec, Inc. Iontophoretic fluid delivery device
JP3993773B2 (ja) * 2002-02-20 2007-10-17 株式会社日立製作所 ストレージサブシステム、記憶制御装置及びデータコピー方法
WO2003072165A2 (en) * 2002-02-28 2003-09-04 Ekos Corporation Ultrasound assembly for use with a catheter
KR20040093058A (ko) * 2002-02-28 2004-11-04 노파르티스 아게 Ｎ-(5-(4-(4-메틸-피페라지노-메틸)-벤조일아미도-2-메틸페닐)-4-(3-피리딜)-2-피리미딘-아민 코팅된 스텐트
DE20203840U1 (de) * 2002-03-09 2002-11-14 Brodersen Jens Sklerosierungskatheter zur Verödung von Krampfadern im Beinbereich
ATE386568T1 (de) 2002-03-09 2008-03-15 Jens P Brodersen Sklerosierungskatheter zur sklerosierung von blutgefässen insbesondere venen
US7919075B1 (en) 2002-03-20 2011-04-05 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices
US8226629B1 (en) 2002-04-01 2012-07-24 Ekos Corporation Ultrasonic catheter power control
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US6978174B2 (en) * 2002-04-08 2005-12-20 Ardian, Inc. Methods and devices for renal nerve blocking
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US7162303B2 (en) * 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US8145317B2 (en) * 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US7620451B2 (en) 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US8131371B2 (en) * 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US20110207758A1 (en) * 2003-04-08 2011-08-25 Medtronic Vascular, Inc. Methods for Therapeutic Renal Denervation
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US8150520B2 (en) * 2002-04-08 2012-04-03 Ardian, Inc. Methods for catheter-based renal denervation
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US7853333B2 (en) * 2002-04-08 2010-12-14 Ardian, Inc. Methods and apparatus for multi-vessel renal neuromodulation
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20030208166A1 (en) * 2002-05-06 2003-11-06 Schwartz Anthony H. Implantable device with free-flowing exit and uses thereof
US7070798B1 (en) 2002-06-21 2006-07-04 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine
US7056523B1 (en) 2002-06-21 2006-06-06 Advanced Cardiovascular Systems, Inc. Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine
US7033602B1 (en) 2002-06-21 2006-04-25 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of coating implantable medical devices
US7011842B1 (en) 2002-06-21 2006-03-14 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of making the same
US8506617B1 (en) 2002-06-21 2013-08-13 Advanced Cardiovascular Systems, Inc. Micronized peptide coated stent
US7217426B1 (en) 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
US7794743B2 (en) 2002-06-21 2010-09-14 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of making the same
US6994867B1 (en) 2002-06-21 2006-02-07 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing L-arginine
US20040082859A1 (en) 2002-07-01 2004-04-29 Alan Schaer Method and apparatus employing ultrasound energy to treat body sphincters
US20040034336A1 (en) * 2002-08-08 2004-02-19 Neal Scott Charged liposomes/micelles with encapsulted medical compounds
US7732535B2 (en) * 2002-09-05 2010-06-08 Advanced Cardiovascular Systems, Inc. Coating for controlled release of drugs from implantable medical devices
US20040054104A1 (en) * 2002-09-05 2004-03-18 Pacetti Stephen D. Coatings for drug delivery devices comprising modified poly(ethylene-co-vinyl alcohol)
EP2668933A1 (de) * 2002-09-20 2013-12-04 Innovational Holdings, LLC Expandierbare medizinische Vorrichtung mit Öffnungen zur Freisetzung mehrerer Wirkstoffe
US20040127976A1 (en) * 2002-09-20 2004-07-01 Conor Medsystems, Inc. Method and apparatus for loading a beneficial agent into an expandable medical device
JP2006500996A (ja) * 2002-09-26 2006-01-12 エンドバスキュラー デバイセス インコーポレイテッド 溶出性生体適合性移植可能医療器具を介してマイトマイシンを送達するための装置および方法
US7008411B1 (en) * 2002-09-30 2006-03-07 Advanced Cardiovascular Systems, Inc. Method and apparatus for treating vulnerable plaque
US20060265043A1 (en) * 2002-09-30 2006-11-23 Evgenia Mandrusov Method and apparatus for treating vulnerable plaque
US8317816B2 (en) 2002-09-30 2012-11-27 Acclarent, Inc. Balloon catheters and methods for treating paranasal sinuses
US7326238B1 (en) 2002-09-30 2008-02-05 Abbott Cardiovascular Systems Inc. Method and apparatus for treating vulnerable plaque
US7087263B2 (en) * 2002-10-09 2006-08-08 Advanced Cardiovascular Systems, Inc. Rare limiting barriers for implantable medical devices
US6921371B2 (en) * 2002-10-14 2005-07-26 Ekos Corporation Ultrasound radiating members for catheter
US6733536B1 (en) * 2002-10-22 2004-05-11 Scimed Life Systems Male urethral stent device
US7048714B2 (en) 2002-10-30 2006-05-23 Biorest Ltd. Drug eluting medical device with an expandable portion for drug release
US7169178B1 (en) 2002-11-12 2007-01-30 Advanced Cardiovascular Systems, Inc. Stent with drug coating
US7022372B1 (en) 2002-11-12 2006-04-04 Advanced Cardiovascular Systems, Inc. Compositions for coating implantable medical devices
US6896965B1 (en) 2002-11-12 2005-05-24 Advanced Cardiovascular Systems, Inc. Rate limiting barriers for implantable devices
US6982004B1 (en) * 2002-11-26 2006-01-03 Advanced Cardiovascular Systems, Inc. Electrostatic loading of drugs on implantable medical devices
US7776926B1 (en) 2002-12-11 2010-08-17 Advanced Cardiovascular Systems, Inc. Biocompatible coating for implantable medical devices
US7758880B2 (en) * 2002-12-11 2010-07-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications
US7074276B1 (en) 2002-12-12 2006-07-11 Advanced Cardiovascular Systems, Inc. Clamp mandrel fixture and a method of using the same to minimize coating defects
US7758881B2 (en) 2004-06-30 2010-07-20 Advanced Cardiovascular Systems, Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US7094256B1 (en) 2002-12-16 2006-08-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical device containing polycationic peptides
US20060002968A1 (en) * 2004-06-30 2006-01-05 Gordon Stewart Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders
US8435550B2 (en) 2002-12-16 2013-05-07 Abbot Cardiovascular Systems Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
AU2003300202A1 (en) * 2003-01-02 2004-07-29 Novoste Corporation Drug delivery balloon catheter
WO2004060448A2 (en) * 2003-01-03 2004-07-22 Ekos Corporation Ultrasonic catheter with axial energy field
WO2004070396A2 (en) 2003-02-10 2004-08-19 N-Trig Ltd. Touch detection for a digitizer
US7563483B2 (en) * 2003-02-26 2009-07-21 Advanced Cardiovascular Systems Inc. Methods for fabricating a coating for implantable medical devices
US7063884B2 (en) 2003-02-26 2006-06-20 Advanced Cardiovascular Systems, Inc. Stent coating
US6926919B1 (en) * 2003-02-26 2005-08-09 Advanced Cardiovascular Systems, Inc. Method for fabricating a coating for a medical device
US11439815B2 (en) 2003-03-10 2022-09-13 Impulse Dynamics Nv Protein activity modification
US7840262B2 (en) * 2003-03-10 2010-11-23 Impulse Dynamics Nv Apparatus and method for delivering electrical signals to modify gene expression in cardiac tissue
US7018398B2 (en) * 2003-03-18 2006-03-28 Elmedical Ltd. System and method for treating urinary tract disorders
AU2004226327A1 (en) * 2003-03-28 2004-10-14 Innovational Holdings, Llc Implantable medical device with beneficial agent concentration gradient
US7566318B2 (en) * 2003-04-11 2009-07-28 Cardiac Pacemakers, Inc. Ultrasonic subcutaneous dissection tool incorporating fluid delivery
US7529592B2 (en) * 2003-04-11 2009-05-05 Cardiac Pacemakers, Inc. Subcutaneous electrode and lead with temporary pharmacological agents
US20040204735A1 (en) * 2003-04-11 2004-10-14 Shiroff Jason Alan Subcutaneous dissection tool incorporating pharmacological agent delivery
US7702399B2 (en) * 2003-04-11 2010-04-20 Cardiac Pacemakers, Inc. Subcutaneous electrode and lead with phoresis based pharmacological agent delivery
EP1619995A2 (de) * 2003-04-22 2006-02-01 Ekos Corporation Ultraschallverstärkter zentralvenöser katheter
US7517342B2 (en) * 2003-04-29 2009-04-14 Boston Scientific Scimed, Inc. Polymer coated device for electrically medicated drug delivery
US7279174B2 (en) 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
US7651529B2 (en) * 2003-05-09 2010-01-26 Boston Scientific Scimed, Inc. Stricture retractor
US20040226556A1 (en) * 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US7201745B2 (en) * 2003-05-13 2007-04-10 Boston Scientific Scimed, Inc. Anti-infective central venous catheter with diffusion barrier layer
US7323209B1 (en) * 2003-05-15 2008-01-29 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating stents
US7862575B2 (en) * 2003-05-21 2011-01-04 Yale University Vascular ablation apparatus and method
US20040236410A1 (en) * 2003-05-22 2004-11-25 Atrium Medical Corp. Polymeric body formation
US20040236278A1 (en) * 2003-05-22 2004-11-25 Atrium Medical Corp. Therapeutic agent delivery
AU2004251673B2 (en) 2003-06-04 2010-01-28 Synecor Llc Intravascular electrophysiological system and methods
US7082336B2 (en) * 2003-06-04 2006-07-25 Synecor, Llc Implantable intravascular device for defibrillation and/or pacing
US7617007B2 (en) * 2003-06-04 2009-11-10 Synecor Llc Method and apparatus for retaining medical implants within body vessels
US8239045B2 (en) * 2003-06-04 2012-08-07 Synecor Llc Device and method for retaining a medical device within a vessel
US7169179B2 (en) * 2003-06-05 2007-01-30 Conor Medsystems, Inc. Drug delivery device and method for bi-directional drug delivery
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US8792985B2 (en) * 2003-07-21 2014-07-29 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US20050021127A1 (en) * 2003-07-21 2005-01-27 Kawula Paul John Porous glass fused onto stent for drug retention
US7056591B1 (en) 2003-07-30 2006-06-06 Advanced Cardiovascular Systems, Inc. Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same
US7645474B1 (en) 2003-07-31 2010-01-12 Advanced Cardiovascular Systems, Inc. Method and system of purifying polymers for use with implantable medical devices
US7785512B1 (en) 2003-07-31 2010-08-31 Advanced Cardiovascular Systems, Inc. Method and system of controlled temperature mixing and molding of polymers with active agents for implantable medical devices
US7431959B1 (en) * 2003-07-31 2008-10-07 Advanced Cardiovascular Systems Inc. Method and system for irradiation of a drug eluting implantable medical device
US8740844B2 (en) * 2003-08-20 2014-06-03 Boston Scientific Scimed, Inc. Medical device with drug delivery member
AU2004285412A1 (en) 2003-09-12 2005-05-12 Minnow Medical, Llc Selectable eccentric remodeling and/or ablation of atherosclerotic material
US7438714B2 (en) * 2003-09-12 2008-10-21 Boston Scientific Scimed, Inc. Vacuum-based catheter stabilizer
US20050059963A1 (en) * 2003-09-12 2005-03-17 Scimed Life Systems, Inc. Systems and method for creating transmural lesions
US8021331B2 (en) * 2003-09-15 2011-09-20 Atrium Medical Corporation Method of coating a folded medical device
US20050113687A1 (en) * 2003-09-15 2005-05-26 Atrium Medical Corporation Application of a therapeutic substance to a tissue location using a porous medical device
US7785653B2 (en) * 2003-09-22 2010-08-31 Innovational Holdings Llc Method and apparatus for loading a beneficial agent into an expandable medical device
US7441513B1 (en) 2003-09-26 2008-10-28 Advanced Cardiovascular Systems, Inc. Plasma-generated coating apparatus for medical devices and a method of coating deposition
US7198675B2 (en) * 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
US7318932B2 (en) * 2003-09-30 2008-01-15 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same
US7704544B2 (en) * 2003-10-07 2010-04-27 Advanced Cardiovascular Systems, Inc. System and method for coating a tubular implantable medical device
EP1525898A1 (de) * 2003-10-23 2005-04-27 Acrostak Corp. Verfahren und Anordnung für einen Applikationskatheter
US20050137520A1 (en) * 2003-10-29 2005-06-23 Rule Peter R. Catheter with ultrasound-controllable porous membrane
US7329413B1 (en) * 2003-11-06 2008-02-12 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
US7524275B2 (en) * 2003-11-14 2009-04-28 Cytyc Corporation Drug eluting brachytherapy methods and apparatus
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
US8192752B2 (en) 2003-11-21 2012-06-05 Advanced Cardiovascular Systems, Inc. Coatings for implantable devices including biologically erodable polyesters and methods for fabricating the same
US7560492B1 (en) * 2003-11-25 2009-07-14 Advanced Cardiovascular Systems, Inc. Polysulfone block copolymers as drug-eluting coating material
US7807722B2 (en) * 2003-11-26 2010-10-05 Advanced Cardiovascular Systems, Inc. Biobeneficial coating compositions and methods of making and using thereof
US7747335B2 (en) * 2003-12-12 2010-06-29 Synecor Llc Implantable medical device having pre-implant exoskeleton
US7220816B2 (en) 2003-12-16 2007-05-22 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same
US7435788B2 (en) 2003-12-19 2008-10-14 Advanced Cardiovascular Systems, Inc. Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
US20060058708A1 (en) * 2003-12-24 2006-03-16 Gill Heart Method and apparatus for ultrasonically increasing the transportation of therapeutic substances through tissue
US8309112B2 (en) * 2003-12-24 2012-11-13 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same
US20050209578A1 (en) * 2004-01-29 2005-09-22 Christian Evans Edward A Ultrasonic catheter with segmented fluid delivery
US7201737B2 (en) * 2004-01-29 2007-04-10 Ekos Corporation Treatment of vascular occlusions using elevated temperatures
JP2007526316A (ja) * 2004-03-01 2007-09-13 ルーメン セラピューティックス リミテッド ライアビリティ カンパニー 疾患を処置するための組成物および方法
US8352031B2 (en) * 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
US11779768B2 (en) 2004-03-10 2023-10-10 Impulse Dynamics Nv Protein activity modification
US7775087B2 (en) * 2004-03-16 2010-08-17 Northwestern University Microchannel forming method and nanotipped dispensing device having a microchannel
US8685431B2 (en) 2004-03-16 2014-04-01 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on copolymers having ester bonds and methods for fabricating the same
US8551512B2 (en) 2004-03-22 2013-10-08 Advanced Cardiovascular Systems, Inc. Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
US20050208093A1 (en) * 2004-03-22 2005-09-22 Thierry Glauser Phosphoryl choline coating compositions
CN104292321A (zh) 2004-03-29 2015-01-21 株式会社嘉尔药物 新的半乳凝素9 突变体蛋白质及其用途
US8778014B1 (en) 2004-03-31 2014-07-15 Advanced Cardiovascular Systems, Inc. Coatings for preventing balloon damage to polymer coated stents
US8146400B2 (en) 2004-04-21 2012-04-03 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9089258B2 (en) * 2004-04-21 2015-07-28 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9554691B2 (en) * 2004-04-21 2017-01-31 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US20070208252A1 (en) 2004-04-21 2007-09-06 Acclarent, Inc. Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses
US10188413B1 (en) 2004-04-21 2019-01-29 Acclarent, Inc. Deflectable guide catheters and related methods
US7462175B2 (en) 2004-04-21 2008-12-09 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US7559925B2 (en) * 2006-09-15 2009-07-14 Acclarent Inc. Methods and devices for facilitating visualization in a surgical environment
US20110004057A1 (en) * 2004-04-21 2011-01-06 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US20070167682A1 (en) 2004-04-21 2007-07-19 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8702626B1 (en) 2004-04-21 2014-04-22 Acclarent, Inc. Guidewires for performing image guided procedures
US7410480B2 (en) 2004-04-21 2008-08-12 Acclarent, Inc. Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
US7419497B2 (en) 2004-04-21 2008-09-02 Acclarent, Inc. Methods for treating ethmoid disease
US8894614B2 (en) 2004-04-21 2014-11-25 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US7803150B2 (en) 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8932276B1 (en) 2004-04-21 2015-01-13 Acclarent, Inc. Shapeable guide catheters and related methods
US20060004323A1 (en) 2004-04-21 2006-01-05 Exploramed Nc1, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US8764729B2 (en) * 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
US7361168B2 (en) * 2004-04-21 2008-04-22 Acclarent, Inc. Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders
US9399121B2 (en) 2004-04-21 2016-07-26 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US20190314620A1 (en) 2004-04-21 2019-10-17 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US8747389B2 (en) 2004-04-21 2014-06-10 Acclarent, Inc. Systems for treating disorders of the ear, nose and throat
US8864787B2 (en) 2004-04-21 2014-10-21 Acclarent, Inc. Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
US20060063973A1 (en) 2004-04-21 2006-03-23 Acclarent, Inc. Methods and apparatus for treating disorders of the ear, nose and throat
US9101384B2 (en) * 2004-04-21 2015-08-11 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat
US9351750B2 (en) 2004-04-21 2016-05-31 Acclarent, Inc. Devices and methods for treating maxillary sinus disease
US20050288481A1 (en) * 2004-04-30 2005-12-29 Desnoyer Jessica R Design of poly(ester amides) for the control of agent-release from polymeric compositions
US8293890B2 (en) 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
US7820732B2 (en) * 2004-04-30 2010-10-26 Advanced Cardiovascular Systems, Inc. Methods for modulating thermal and mechanical properties of coatings on implantable devices
US20050265960A1 (en) * 2004-05-26 2005-12-01 Pacetti Stephen D Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same
US8377484B1 (en) 2004-05-06 2013-02-19 Maria V. Tsiper Tumor encapsulation for prevention and treatment of metastatic cancer disease
US9561309B2 (en) 2004-05-27 2017-02-07 Advanced Cardiovascular Systems, Inc. Antifouling heparin coatings
US7563780B1 (en) 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
US20050287184A1 (en) 2004-06-29 2005-12-29 Hossainy Syed F A Drug-delivery stent formulations for restenosis and vulnerable plaque
US8357391B2 (en) 2004-07-30 2013-01-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable devices comprising poly (hydroxy-alkanoates) and diacid linkages
US7494665B1 (en) 2004-07-30 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymers containing siloxane monomers
US7311980B1 (en) 2004-08-02 2007-12-25 Advanced Cardiovascular Systems, Inc. Polyactive/polylactic acid coatings for an implantable device
AU2012201954B2 (en) * 2004-08-04 2013-01-24 Acclarent, Inc. Implantable devices and methods for delivering drugs and other substances to treat sinusitis and other disorders
AU2005277797A1 (en) * 2004-08-19 2006-03-02 Vein Rx, Inc. An occludable intravascular catheter for drug delivery and method of using the same
US20080275393A1 (en) * 2004-08-24 2008-11-06 Bonnette Michael J Isolation thrombectomy catheter system
US9283099B2 (en) * 2004-08-25 2016-03-15 Advanced Cardiovascular Systems, Inc. Stent-catheter assembly with a releasable connection for stent retention
US7648727B2 (en) * 2004-08-26 2010-01-19 Advanced Cardiovascular Systems, Inc. Methods for manufacturing a coated stent-balloon assembly
US7244443B2 (en) 2004-08-31 2007-07-17 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrophilic monomers
US7742795B2 (en) 2005-03-28 2010-06-22 Minnow Medical, Inc. Tuned RF energy for selective treatment of atheroma and other target tissues and/or structures
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US9277955B2 (en) 2010-04-09 2016-03-08 Vessix Vascular, Inc. Power generating and control apparatus for the treatment of tissue
US7063720B2 (en) * 2004-09-14 2006-06-20 The Wallace Enterprises, Inc. Covered stent with controlled therapeutic agent diffusion
US8110211B2 (en) 2004-09-22 2012-02-07 Advanced Cardiovascular Systems, Inc. Medicated coatings for implantable medical devices including polyacrylates
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US8962023B2 (en) 2004-09-28 2015-02-24 Atrium Medical Corporation UV cured gel and method of making
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US7166680B2 (en) 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
US20060079841A1 (en) * 2004-10-07 2006-04-13 University Technologies International Inc. Rapid insufflation drug compartment
US8603634B2 (en) 2004-10-27 2013-12-10 Abbott Cardiovascular Systems Inc. End-capped poly(ester amide) copolymers
US20060094945A1 (en) * 2004-10-28 2006-05-04 Sontra Medical Corporation System and method for analyte sampling and analysis
US7390497B2 (en) 2004-10-29 2008-06-24 Advanced Cardiovascular Systems, Inc. Poly(ester amide) filler blends for modulation of coating properties
US7481835B1 (en) 2004-10-29 2009-01-27 Advanced Cardiovascular Systems, Inc. Encapsulated covered stent
US7937143B2 (en) 2004-11-02 2011-05-03 Ardian, Inc. Methods and apparatus for inducing controlled renal neuromodulation
US20070083239A1 (en) * 2005-09-23 2007-04-12 Denise Demarais Methods and apparatus for inducing, monitoring and controlling renal neuromodulation
US7214759B2 (en) * 2004-11-24 2007-05-08 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
US7588642B1 (en) 2004-11-29 2009-09-15 Advanced Cardiovascular Systems, Inc. Abluminal stent coating apparatus and method using a brush assembly
US8609123B2 (en) 2004-11-29 2013-12-17 Advanced Cardiovascular Systems, Inc. Derivatized poly(ester amide) as a biobeneficial coating
US7892592B1 (en) 2004-11-30 2011-02-22 Advanced Cardiovascular Systems, Inc. Coating abluminal surfaces of stents and other implantable medical devices
US8262605B2 (en) 2004-12-09 2012-09-11 Ams Research Corporation Needleless delivery systems
EP1827571B1 (de) * 2004-12-09 2016-09-07 Impulse Dynamics NV Proteinaktivitätsmodifizierung
US7604818B2 (en) 2004-12-22 2009-10-20 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrocarbon monomers
KR20060072734A (ko) * 2004-12-23 2006-06-28 두산인프라코어 주식회사 건설중장비의 압축공기 공급장치
US7419504B2 (en) * 2004-12-27 2008-09-02 Advanced Cardiovascular Systems, Inc. Poly(ester amide) block copolymers
CA2592922A1 (en) * 2004-12-29 2006-07-06 Mannkind Corporation Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
US8007775B2 (en) 2004-12-30 2011-08-30 Advanced Cardiovascular Systems, Inc. Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
US8287583B2 (en) * 2005-01-10 2012-10-16 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
US20070150051A1 (en) * 2005-01-10 2007-06-28 Duke Fiduciary, Llc Vascular implants and methods of fabricating the same
US7202325B2 (en) * 2005-01-14 2007-04-10 Advanced Cardiovascular Systems, Inc. Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles
US7850645B2 (en) * 2005-02-11 2010-12-14 Boston Scientific Scimed, Inc. Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
US9821158B2 (en) 2005-02-17 2017-11-21 Metacure Limited Non-immediate effects of therapy
WO2006097934A2 (en) * 2005-03-18 2006-09-21 Metacure Limited Pancreas lead
US20060216431A1 (en) * 2005-03-28 2006-09-28 Kerrigan Cameron K Electrostatic abluminal coating of a stent crimped on a balloon catheter
US7795467B1 (en) 2005-04-26 2010-09-14 Advanced Cardiovascular Systems, Inc. Bioabsorbable, biobeneficial polyurethanes for use in medical devices
US8778375B2 (en) * 2005-04-29 2014-07-15 Advanced Cardiovascular Systems, Inc. Amorphous poly(D,L-lactide) coating
EP1898991B1 (de) * 2005-05-04 2016-06-29 Impulse Dynamics NV Proteinaktivitätsmodifizierung
US7637941B1 (en) 2005-05-11 2009-12-29 Advanced Cardiovascular Systems, Inc. Endothelial cell binding coatings for rapid encapsulation of bioerodable stents
US8460357B2 (en) * 2005-05-31 2013-06-11 J.W. Medical Systems Ltd. In situ stent formation
WO2006133193A1 (en) * 2005-06-07 2006-12-14 American Medical Systems Research Corporation Injection guidance system and method
US7938851B2 (en) * 2005-06-08 2011-05-10 Xtent, Inc. Devices and methods for operating and controlling interventional apparatus
US8157851B2 (en) * 2005-06-08 2012-04-17 Xtent, Inc. Apparatus and methods for deployment of multiple custom-length prostheses
US8951225B2 (en) 2005-06-10 2015-02-10 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US7823533B2 (en) 2005-06-30 2010-11-02 Advanced Cardiovascular Systems, Inc. Stent fixture and method for reducing coating defects
US8021676B2 (en) 2005-07-08 2011-09-20 Advanced Cardiovascular Systems, Inc. Functionalized chemically inert polymers for coatings
EP1901796B1 (de) * 2005-07-08 2020-11-11 C. R. Bard, Inc. Vorrichtung zur Verabreichung einer implantierbaren medizinischen Einrichtung
US20070025869A1 (en) * 2005-07-15 2007-02-01 Gordon John H Fluid Delivery Device
US7655243B2 (en) 2005-07-22 2010-02-02 The Foundry, Llc Methods and systems for toxin delivery to the nasal cavity
US10052465B2 (en) 2005-07-22 2018-08-21 The Foundry, Llc Methods and systems for toxin delivery to the nasal cavity
JP5826450B2 (ja) * 2005-07-22 2015-12-02 ザ ファウンドリー， エルエルシー 治療薬の送達のためのシステムおよび方法
US7785647B2 (en) 2005-07-25 2010-08-31 Advanced Cardiovascular Systems, Inc. Methods of providing antioxidants to a drug containing product
US7735449B1 (en) 2005-07-28 2010-06-15 Advanced Cardiovascular Systems, Inc. Stent fixture having rounded support structures and method for use thereof
US8114113B2 (en) 2005-09-23 2012-02-14 Acclarent, Inc. Multi-conduit balloon catheter
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US20070233185A1 (en) 2005-10-20 2007-10-04 Thomas Anderson Systems and methods for sealing a vascular opening
US8162878B2 (en) 2005-12-05 2012-04-24 Medrad, Inc. Exhaust-pressure-operated balloon catheter system
US7432069B2 (en) * 2005-12-05 2008-10-07 Sontra Medical Corporation Biocompatible chemically crosslinked hydrogels for glucose sensing
US8197441B2 (en) * 2005-12-06 2012-06-12 Abbott Cardiovascular Systems Inc. Catheter mounted automatic vessel occlusion and fluid dispersion devices
US7591841B2 (en) 2005-12-16 2009-09-22 Advanced Cardiovascular Systems, Inc. Implantable devices for accelerated healing
US7976891B1 (en) 2005-12-16 2011-07-12 Advanced Cardiovascular Systems, Inc. Abluminal stent coating apparatus and method of using focused acoustic energy
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
US7638156B1 (en) 2005-12-19 2009-12-29 Advanced Cardiovascular Systems, Inc. Apparatus and method for selectively coating a medical article
US20070148251A1 (en) * 2005-12-22 2007-06-28 Hossainy Syed F A Nanoparticle releasing medical devices
US20080243068A1 (en) * 2005-12-29 2008-10-02 Kamal Ramzipoor Methods and apparatus for treatment of venous insufficiency
US20070179518A1 (en) * 2006-02-02 2007-08-02 Becker Bruce B Balloon Catheters and Methods for Treating Paranasal Sinuses
US20070196428A1 (en) 2006-02-17 2007-08-23 Thierry Glauser Nitric oxide generating medical devices
US7601383B2 (en) 2006-02-28 2009-10-13 Advanced Cardiovascular Systems, Inc. Coating construct containing poly (vinyl alcohol)
US7713637B2 (en) 2006-03-03 2010-05-11 Advanced Cardiovascular Systems, Inc. Coating containing PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid polymer
US8888684B2 (en) * 2006-03-27 2014-11-18 Boston Scientific Scimed, Inc. Medical devices with local drug delivery capabilities
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US7985441B1 (en) 2006-05-04 2011-07-26 Yiwen Tang Purification of polymers for coating applications
US8003156B2 (en) 2006-05-04 2011-08-23 Advanced Cardiovascular Systems, Inc. Rotatable support elements for stents
US8304012B2 (en) 2006-05-04 2012-11-06 Advanced Cardiovascular Systems, Inc. Method for drying a stent
US8190389B2 (en) 2006-05-17 2012-05-29 Acclarent, Inc. Adapter for attaching electromagnetic image guidance components to a medical device
US7775178B2 (en) 2006-05-26 2010-08-17 Advanced Cardiovascular Systems, Inc. Stent coating apparatus and method
US9561351B2 (en) 2006-05-31 2017-02-07 Advanced Cardiovascular Systems, Inc. Drug delivery spiral coil construct
US8568764B2 (en) * 2006-05-31 2013-10-29 Advanced Cardiovascular Systems, Inc. Methods of forming coating layers for medical devices utilizing flash vaporization
US8703167B2 (en) 2006-06-05 2014-04-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
US8778376B2 (en) 2006-06-09 2014-07-15 Advanced Cardiovascular Systems, Inc. Copolymer comprising elastin pentapeptide block and hydrophilic block, and medical device and method of treating
US8114150B2 (en) 2006-06-14 2012-02-14 Advanced Cardiovascular Systems, Inc. RGD peptide attached to bioabsorbable stents
US8603530B2 (en) 2006-06-14 2013-12-10 Abbott Cardiovascular Systems Inc. Nanoshell therapy
US8048448B2 (en) * 2006-06-15 2011-11-01 Abbott Cardiovascular Systems Inc. Nanoshells for drug delivery
US8017237B2 (en) 2006-06-23 2011-09-13 Abbott Cardiovascular Systems, Inc. Nanoshells on polymers
KR20090045916A (ko) * 2006-07-03 2009-05-08 헤모텍 아게 혈관의 영구 개방을 위한 활성 물질 방출용 의약 제품, 그의 제조 방법 및 용도
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
US8685430B1 (en) 2006-07-14 2014-04-01 Abbott Cardiovascular Systems Inc. Tailored aliphatic polyesters for stent coatings
US20080097300A1 (en) * 2006-08-07 2008-04-24 Sherif Eskaros Catheter balloon with multiple micropleats
US20080097374A1 (en) * 2006-08-07 2008-04-24 Korleski Joseph E Inflatable shaped balloons
US8460240B2 (en) * 2006-08-07 2013-06-11 W. L. Gore & Associates, Inc. Inflatable toroidal-shaped balloons
US7785290B2 (en) * 2006-08-07 2010-08-31 Gore Enterprise Holdings, Inc. Non-shortening high angle wrapped balloons
US9180279B2 (en) 2006-08-07 2015-11-10 W. L. Gore & Associates, Inc. Inflatable imbibed polymer devices
US20080140173A1 (en) * 2006-08-07 2008-06-12 Sherif Eskaros Non-shortening wrapped balloon
US20080125711A1 (en) 2006-08-07 2008-05-29 Alpini Alfred A Catheter balloons with integrated non-distensible seals
US8703169B1 (en) 2006-08-15 2014-04-22 Abbott Cardiovascular Systems Inc. Implantable device having a coating comprising carrageenan and a biostable polymer
WO2008027416A2 (en) * 2006-08-29 2008-03-06 Tissue Genesis Catheter for cell delivery
US8260411B1 (en) 2006-09-06 2012-09-04 Twin Star Medical, Inc. Conductive injection and aspiration device and method
PL2061385T3 (pl) * 2006-09-13 2015-06-30 Vascular Insights Llc Urządzenie do zabiegów naczyniowych
US9820688B2 (en) 2006-09-15 2017-11-21 Acclarent, Inc. Sinus illumination lightwire device
US7780730B2 (en) 2006-09-25 2010-08-24 Iyad Saidi Nasal implant introduced through a non-surgical injection technique
CA2666661C (en) * 2006-10-18 2015-01-20 Minnow Medical, Inc. Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
EP2455034B1 (de) 2006-10-18 2017-07-19 Vessix Vascular, Inc. System zur Herbeiführung gewünschter Temperatureffekte auf Körpergewebe
JP5479901B2 (ja) 2006-10-18 2014-04-23 べシックス・バスキュラー・インコーポレイテッド 身体組織に対する所望の温度作用の誘発
US8192363B2 (en) * 2006-10-27 2012-06-05 Ekos Corporation Catheter with multiple ultrasound radiating members
US20100286791A1 (en) * 2006-11-21 2010-11-11 Goldsmith David S Integrated system for the ballistic and nonballistic infixion and retrieval of implants
ITMI20062333A1 (it) * 2006-12-05 2008-06-06 Mario Salerno Dispositivo per assistere il trattamento scloresante delle vene varicose
US20080140002A1 (en) * 2006-12-06 2008-06-12 Kamal Ramzipoor System for delivery of biologically active substances with actuating three dimensional surface
US8597673B2 (en) 2006-12-13 2013-12-03 Advanced Cardiovascular Systems, Inc. Coating of fast absorption or dissolution
US20080147186A1 (en) * 2006-12-14 2008-06-19 Joshi Ashok V Electrochemical Implant For Delivering Beneficial Agents
US8439687B1 (en) 2006-12-29 2013-05-14 Acclarent, Inc. Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices
US10182833B2 (en) 2007-01-08 2019-01-22 Ekos Corporation Power parameters for ultrasonic catheter
US7765015B2 (en) * 2007-01-12 2010-07-27 Cardiac Pacemakers, Inc. Lead with inflatable fixation mechanism
RU2447901C2 (ru) * 2007-01-21 2012-04-20 Хемотек Аг Медицинский продукт для лечения обтураций просветов организма и для предупреждения угрожающих повторных обтураций
US20080177219A1 (en) * 2007-01-23 2008-07-24 Joshi Ashok V Method for Iontophoretic Fluid Delivery
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
JP2010517703A (ja) * 2007-02-09 2010-05-27 タヘリ ラドュカ エルエルシー 血管移植片およびそれを加工する方法
US7938286B2 (en) * 2007-02-13 2011-05-10 Gateway Plastics, Inc. Container system
US20080200873A1 (en) * 2007-02-16 2008-08-21 Alejandro Espinosa Methods and Apparatus for Infusing the Interior of a Blood Vessel
US8812071B2 (en) * 2007-03-07 2014-08-19 Echo Therapeutics, Inc. Transdermal analyte monitoring systems and methods for analyte detection
AU2008224435B2 (en) * 2007-03-15 2014-01-09 Ortho-Space Ltd. Prosthetic devices and methods for using same
US8496653B2 (en) * 2007-04-23 2013-07-30 Boston Scientific Scimed, Inc. Thrombus removal
US20080269665A1 (en) * 2007-04-24 2008-10-30 Johan Petersen Chemotherapy delivery device
US8386027B2 (en) 2007-04-27 2013-02-26 Echo Therapeutics, Inc. Skin permeation device for analyte sensing or transdermal drug delivery
US8118757B2 (en) 2007-04-30 2012-02-21 Acclarent, Inc. Methods and devices for ostium measurement
US8485199B2 (en) 2007-05-08 2013-07-16 Acclarent, Inc. Methods and devices for protecting nasal turbinate during surgery
US8147769B1 (en) 2007-05-16 2012-04-03 Abbott Cardiovascular Systems Inc. Stent and delivery system with reduced chemical degradation
US9056155B1 (en) 2007-05-29 2015-06-16 Abbott Cardiovascular Systems Inc. Coatings having an elastic primer layer
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US9044568B2 (en) 2007-06-22 2015-06-02 Ekos Corporation Method and apparatus for treatment of intracranial hemorrhages
US8048441B2 (en) 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
US8109904B1 (en) 2007-06-25 2012-02-07 Abbott Cardiovascular Systems Inc. Drug delivery medical devices
US9192697B2 (en) * 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US20090018446A1 (en) * 2007-07-10 2009-01-15 Insightec, Ltd. Transrectal ultrasound ablation probe
US20090030409A1 (en) * 2007-07-27 2009-01-29 Eric Goldfarb Methods and devices for facilitating visualization in a surgical environment
WO2009079415A1 (en) * 2007-12-14 2009-06-25 Ekos Corporation Ultrasound pulse shaping
WO2009079539A1 (en) * 2007-12-17 2009-06-25 Medrad, Inc. Rheolytic thrombectomy catheter with self-inflation distal balloon
US8211489B2 (en) * 2007-12-19 2012-07-03 Abbott Cardiovascular Systems, Inc. Methods for applying an application material to an implantable device
US20090187254A1 (en) * 2007-12-19 2009-07-23 Boston Scientific Scimed, Inc. Urological medical devices for release of urologically beneficial agents
US8361538B2 (en) 2007-12-19 2013-01-29 Abbott Laboratories Methods for applying an application material to an implantable device
US10206821B2 (en) 2007-12-20 2019-02-19 Acclarent, Inc. Eustachian tube dilation balloon with ventilation path
US8439878B2 (en) * 2007-12-26 2013-05-14 Medrad, Inc. Rheolytic thrombectomy catheter with self-inflating proximal balloon with drug infusion capabilities
US20090170933A1 (en) * 2007-12-26 2009-07-02 Cook Incorporated Method for removing a medical device from a spasmodic constriction in a bodily passageway
US20110106120A1 (en) * 2008-01-18 2011-05-05 Med Institute, Inc. Intravascular device attachment system having tubular expandable body
US8162880B2 (en) * 2008-01-18 2012-04-24 Swaminathan Jayaraman Delivery of therapeutic and marking substance through intra lumen expansion of a delivery device
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
US8157747B2 (en) * 2008-02-15 2012-04-17 Lary Research & Development, Llc Single-use indicator for a surgical instrument and a surgical instrument incorporating same
AU2009219365A1 (en) * 2008-02-25 2009-09-03 Liquidia Technologies, Inc. Delivery apparatus and associated method
US8182432B2 (en) 2008-03-10 2012-05-22 Acclarent, Inc. Corewire design and construction for medical devices
WO2009135125A2 (en) * 2008-05-01 2009-11-05 Bayer Schering Pharma Ag Catheter balloon drug adherence techniques and methods
EP2529686B1 (de) 2008-05-09 2015-10-14 Holaira, Inc. System zur Behandlung eines Bronchialbaumes
US7873404B1 (en) 2008-05-29 2011-01-18 Seth Caplan Method for performing angioplasty and angiography with a single catheter
EP2664350B1 (de) 2008-07-30 2019-08-28 Acclarent, Inc. Vorrichtungen zur Ortung von Nasennebenhöhlen
WO2010033629A1 (en) 2008-09-18 2010-03-25 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
JP5622729B2 (ja) * 2008-09-22 2014-11-12 べシックス・バスキュラー・インコーポレイテッド 身体組織に対して温度効果を誘発するシステム
EP2350664B1 (de) 2008-10-21 2021-05-19 ImmunoGenesis, Inc. Behandlung von krebs anhand vom hypoxie-aktivierten promedikament th-302 in kombinatin mit docetaxel oder pemetrexed
US20100125238A1 (en) * 2008-11-14 2010-05-20 Therawire, Inc. Iontophoretic Therapeutic Agent Delivery System
CN102271603A (zh) 2008-11-17 2011-12-07 明诺医学股份有限公司 得知或未得知组织形态的选择性能量积累
WO2010059586A1 (en) 2008-11-19 2010-05-27 Entrigue Surgical, Inc. Apparatus and methods for correcting nasal valve collapse
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
WO2010080886A1 (en) * 2009-01-09 2010-07-15 Recor Medical, Inc. Methods and apparatus for treatment of mitral valve in insufficiency
US9440024B2 (en) * 2009-01-27 2016-09-13 Becton, Dickinson And Company Infusion set with anesthetic compound
US20110306878A1 (en) 2009-02-26 2011-12-15 Liquidia Technologies, Inc. Interventional drug delivery system and associated methods
US20100241155A1 (en) 2009-03-20 2010-09-23 Acclarent, Inc. Guide system with suction
US8435290B2 (en) * 2009-03-31 2013-05-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US7978742B1 (en) 2010-03-24 2011-07-12 Corning Incorporated Methods for operating diode lasers
WO2010124098A2 (en) * 2009-04-24 2010-10-28 Boston Scientific Scimed, Inc. Use of drug polymorphs to achieve controlled drug delivery from a coated medical device
US8551096B2 (en) 2009-05-13 2013-10-08 Boston Scientific Scimed, Inc. Directional delivery of energy and bioactives
US8591494B2 (en) * 2009-06-10 2013-11-26 Boston Scientific Scimed, Inc. Electrochemical therapeutic agent delivery device
EP3064230B1 (de) 2009-07-10 2019-04-10 Boston Scientific Scimed, Inc. Verwendung von nanokristallen für einen wirkstofffreisetzungsballon
EP2453938B1 (de) 2009-07-17 2015-08-19 Boston Scientific Scimed, Inc. Nukleierung von wirkstofffreisetzungsballons für verbesserte kristallgrösse und -dichte
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
US9649153B2 (en) 2009-10-27 2017-05-16 Holaira, Inc. Delivery devices with coolable energy emitting assemblies
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
CA2780608C (en) 2009-11-11 2019-02-26 Innovative Pulmonary Solutions, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US20110160740A1 (en) * 2009-12-28 2011-06-30 Acclarent, Inc. Tissue Removal in The Paranasal Sinus and Nasal Cavity
US9492687B2 (en) 2009-12-31 2016-11-15 ZetrOZ Systems, LLC Low-profile ultrasound transducer
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
US8685433B2 (en) 2010-03-31 2014-04-01 Abbott Cardiovascular Systems Inc. Absorbable coating for implantable device
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
WO2012009707A2 (en) 2010-07-16 2012-01-19 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
WO2012017438A1 (en) 2010-08-04 2012-02-09 Ortho-Space Ltd. Shoulder implant
EP2611476B1 (de) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Beschichtungsverfahren für wirkstofffreisetzungsballons mit wärmeinduziertem rewrap-gedächtnis
US9155492B2 (en) 2010-09-24 2015-10-13 Acclarent, Inc. Sinus illumination lightwire device
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
EP3449856B1 (de) 2010-10-25 2023-06-28 Medtronic Ardian Luxembourg S.à.r.l. Vorrichtung zur beurteilung und feedback einer neuromodulationsbehandlung
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9585667B2 (en) 2010-11-15 2017-03-07 Vascular Insights Llc Sclerotherapy catheter with lumen having wire rotated by motor and simultaneous withdrawal from vein
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
JP6016805B2 (ja) 2010-12-22 2016-10-26 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 泌尿器科医療デバイス
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US20120259269A1 (en) * 2011-04-08 2012-10-11 Tyco Healthcare Group Lp Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
US11458290B2 (en) 2011-05-11 2022-10-04 Ekos Corporation Ultrasound system
AU2012283908B2 (en) 2011-07-20 2017-02-16 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
WO2013016203A1 (en) 2011-07-22 2013-01-31 Boston Scientific Scimed, Inc. Nerve modulation system with a nerve modulation element positionable in a helical guide
JP5887348B2 (ja) * 2011-07-25 2016-03-16 テルモ株式会社 治療デバイス
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
US9808605B2 (en) 2011-10-06 2017-11-07 W. L. Gore & Associates, Inc. Controlled porosity devices for tissue treatments, methods of use, and methods of manufacture
EP2765942B1 (de) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medizinische vorrichtungen mit ablationselektroden
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
EP2768563B1 (de) 2011-10-18 2016-11-09 Boston Scientific Scimed, Inc. Biegbare medizinische vorrichtungen
WO2013057566A2 (en) 2011-10-18 2013-04-25 Ortho-Space Ltd. Prosthetic devices and methods for using same
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
EP2775948B1 (de) 2011-11-08 2018-04-04 Boston Scientific Scimed, Inc. Ostiale nierennervenablation
EP2779929A1 (de) 2011-11-15 2014-09-24 Boston Scientific Scimed, Inc. Vorrichtung und verfahren zur überwachung von nierennervenmodulation
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
JP2015500054A (ja) * 2011-12-02 2015-01-05 シル ヴァスキュラー リミテッド バルーンカテーテルシステム
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
WO2013096913A2 (en) 2011-12-23 2013-06-27 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
WO2013101452A1 (en) 2011-12-28 2013-07-04 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9750568B2 (en) 2012-03-08 2017-09-05 Medtronic Ardian Luxembourg S.A.R.L. Ovarian neuromodulation and associated systems and methods
WO2013134733A2 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg Sarl Biomarker sampling in the context of neuromodulation devices and associated systems and methods
US20150148780A1 (en) * 2012-03-09 2015-05-28 Clearstream Technologies Limited Medical balloon with a precisely identifiable portion
US8403927B1 (en) 2012-04-05 2013-03-26 William Bruce Shingleton Vasectomy devices and methods
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US9381326B2 (en) * 2012-06-15 2016-07-05 W. L. Gore & Associates, Inc. Vascular occlusion and drug delivery devices, systems, and methods
WO2014018386A1 (en) 2012-07-23 2014-01-30 University Of Utah Research Foundation Indwelling urinary catheter
US9561035B2 (en) * 2012-08-03 2017-02-07 Harold Carrison Vessel flow control devices and methods
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
EP2895095A2 (de) 2012-09-17 2015-07-22 Boston Scientific Scimed, Inc. Selbstpositionierendes elektrodensystem und verfahren für renale nervenmodulation
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
IN2015DN00517A (de) 2012-10-01 2015-06-26 Bard Inc C R
JP6074051B2 (ja) 2012-10-10 2017-02-01 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 血管内神経変調システム及び医療用デバイス
US20140110296A1 (en) 2012-10-19 2014-04-24 Medtronic Ardian Luxembourg S.A.R.L. Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US9050053B2 (en) 2013-02-15 2015-06-09 Naimco, Inc. Ultrasound device with cavity for conductive medium
CA2902468C (en) 2013-02-27 2022-08-16 Spirox, Inc. Nasal implants and systems and methods of use
WO2014143571A1 (en) 2013-03-11 2014-09-18 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
US9433437B2 (en) 2013-03-15 2016-09-06 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
JP6220044B2 (ja) 2013-03-15 2017-10-25 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 腎神経アブレーションのための医療用デバイス
US9629684B2 (en) 2013-03-15 2017-04-25 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
CN105228546B (zh) 2013-03-15 2017-11-14 波士顿科学国际有限公司 利用阻抗补偿的用于治疗高血压的医疗器械和方法
JP2016524949A (ja) 2013-06-21 2016-08-22 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 回転可能シャフトを有する腎神経アブレーション用医療装置
US9943365B2 (en) 2013-06-21 2018-04-17 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
WO2015002787A1 (en) 2013-07-01 2015-01-08 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
EP3019106A1 (de) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medizinische vorrichtung mit dehnbaren elektrodenanordnungen
EP3049007B1 (de) 2013-07-19 2019-06-12 Boston Scientific Scimed, Inc. Nierendenervierungsballon mit spiralförmiger bipolarer elektrode
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10695124B2 (en) 2013-07-22 2020-06-30 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
JP6159888B2 (ja) 2013-08-22 2017-07-05 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 腎神経変調バルーンへの接着性を向上させたフレキシブル回路
US11759186B2 (en) * 2018-06-08 2023-09-19 David S. Goldsmith Ductus side-entry and prosthetic disorder response systems
US9895194B2 (en) 2013-09-04 2018-02-20 Boston Scientific Scimed, Inc. Radio frequency (RF) balloon catheter having flushing and cooling capability
CN105530885B (zh) 2013-09-13 2020-09-22 波士顿科学国际有限公司 具有气相沉积覆盖层的消融球囊
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
WO2015057521A1 (en) 2013-10-14 2015-04-23 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
EP3057520A1 (de) 2013-10-15 2016-08-24 Boston Scientific Scimed, Inc. Ballon für medizinische vorrichtung
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
JP6259099B2 (ja) 2013-10-18 2018-01-10 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 可撓性を備える導電性ワイヤを備えるバルーン・カテーテル、並びに関連する使用および製造方法
CN105658163B (zh) 2013-10-25 2020-08-18 波士顿科学国际有限公司 去神经柔性电路中的嵌入式热电偶
US9682218B2 (en) 2013-12-23 2017-06-20 Carefusion 2200, Inc. Pleurodesis device and method
WO2015103617A1 (en) 2014-01-06 2015-07-09 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
EP3102136B1 (de) 2014-02-04 2018-06-27 Boston Scientific Scimed, Inc. Alternative platzierung von thermischen sensoren auf bipolarer elektrode
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
EP3185819A4 (de) 2014-08-26 2018-03-14 Spirox, Inc. Nasenimplantate und systeme sowie verfahren zur verwendung
US10092742B2 (en) 2014-09-22 2018-10-09 Ekos Corporation Catheter system
WO2016160905A1 (en) * 2015-03-31 2016-10-06 Transmed7, Llc Devices and methods for vascular interventions
MX2017012869A (es) 2015-04-08 2018-08-15 Magnus Schoellhammer Carl Sistemas, aparatos y método para ensamblarlos para administrar una sustancia.
WO2016198947A1 (en) 2015-06-06 2016-12-15 The Hong Kong University Of Science And Technology Radio frequency electro-thrombectomy device
EP3307388B1 (de) 2015-06-10 2022-06-22 Ekos Corporation Ultraschallkatheter
JP6956092B2 (ja) 2015-09-25 2021-10-27 スピロックス, インク.Spirox, Inc. 鼻インプラントとシステム及び使用方法
CN114209420A (zh) 2015-10-07 2022-03-22 梅约医学教育与研究基金会 用于肥胖症或糖尿病治疗的电穿孔
CN108136112B (zh) 2015-10-22 2021-07-30 西托索尔本茨公司 多功能血液相容性多孔聚合物珠吸着剂
WO2017135993A1 (en) * 2016-02-04 2017-08-10 Lynn White Catheter assembly with distinct inflation and drug delivery channels and overlapping balloon layers
US10611752B2 (en) 2016-03-01 2020-04-07 The Board Of Trustees Of The Leland Stanford Junior University Enantioselective destruction of chiral molecules
EP4299100A3 (de) 2016-05-02 2024-03-20 Entellus Medical, Inc. Implantat-deleiver-system für nasenklappenimplantate
JP2019532741A (ja) * 2016-10-20 2019-11-14 レトロバスキュラー インコーポレイテッド 向上した組成物送達のための方法及び装置
US10653541B2 (en) 2016-12-21 2020-05-19 Cook Medical Technologies Llc Stent delivery assembly
WO2018114992A1 (en) * 2016-12-22 2018-06-28 Biotronik Ag Drug releasing coatings for medical devices and methods of making same
US10350395B2 (en) 2017-06-23 2019-07-16 Cook Medical Technologies Llc Introducer for lumen support or dilation
US20190159792A1 (en) * 2017-11-27 2019-05-30 Justin Panian Ultrasound Vessel Preparation and Restenosis Therapy
US20210030467A1 (en) * 2018-02-12 2021-02-04 Flagship Pioneering Innovations V, Inc. Devices and methods for delivering material into a biological tissue or cell
JP2022504917A (ja) * 2018-10-11 2022-01-13 スオーノ バイオ， インコーポレイテッド 繋ぎ止められた超音波デバイスおよびその使用

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US578611A (en) * 1897-03-09 Thirds to louis f
DE147314C (de) *
US725731A (en) * 1901-08-09 1903-04-21 Samuel H Linn Cataphoric electrode.
US873021A (en) * 1907-08-02 1907-12-10 Harlow R Cool Electrotherapeutic syringe.
US2123980A (en) * 1934-07-21 1938-07-19 G M Basford Company Therapeutic treatment
US2499045A (en) * 1948-08-16 1950-02-28 Walker Frank Ray Rectal dilator and medicator
FR1532340A (fr) * 1967-04-06 1968-07-12 Comp Generale Electricite Dispositif de mesure de la largeur d'une cavité du système circulatoire
US3865108A (en) * 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
JPS5512265B2 (de) * 1973-04-24 1980-03-31
US4126134A (en) * 1973-06-13 1978-11-21 Population Research Incorporated Dispensing instrument
CS173836B1 (de) * 1974-03-19 1977-03-31
CH588870A5 (en) * 1975-05-22 1977-06-15 Gaspoz Louis Gerard Catheter with central and interior fluid tubes - has porous section to localise fluid discharge and exterior balloon to limit penetration
FR2361123A1 (fr) * 1976-08-10 1978-03-10 Serat Etu Applic Technologique Catheter pour l'examen ou le traitement d'un vaisseau sanguin et appareil pour son utilisation
US4137906A (en) * 1977-05-05 1979-02-06 Koken Co., Ltd. Catheter apparatus with occlusion and flow diverting means
US4323071A (en) 1978-04-24 1982-04-06 Advanced Catheter Systems, Inc. Vascular guiding catheter assembly and vascular dilating catheter assembly and a combination thereof and methods of making the same
US4301794A (en) * 1978-10-18 1981-11-24 Robert Tapper Method for iontophoretic treatment
DD147314A1 (de) * 1979-11-14 1981-04-01 Manfred R Boehm Intraaortales substrat/pharmaka-ballon-pumpen-system
HU184722B (en) * 1980-02-18 1984-10-29 Laszlo Lazar Therapeutically suitable silicone rubber mixture and therapeuticaid
SU1003853A1 (ru) * 1980-03-17 1983-03-15 Белорусский Научно-Исследовательский Институт Неврологии,Нейрохирургии И Физиотерапии Устройство дл электрофонофореза
US4608984A (en) * 1980-10-17 1986-09-02 Fogarty Thomas J Self-retracting dilatation catheter
US4403612A (en) * 1980-10-20 1983-09-13 Fogarty Thomas J Dilatation method
US4338942A (en) * 1980-10-20 1982-07-13 Fogarty Thomas J Dilatation catherter apparatus
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4364392A (en) * 1980-12-04 1982-12-21 Wisconsin Alumni Research Foundation Detachable balloon catheter
US4416274A (en) * 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
US4411648A (en) * 1981-06-11 1983-10-25 Board Of Regents, The University Of Texas System Iontophoretic catheter device
US4509523A (en) * 1981-07-22 1985-04-09 Pevsner Paul H Method of using miniature balloon catheter for perfusing
DE3235974A1 (de) * 1981-11-24 1983-06-01 Volkmar Dipl.-Ing. Merkel (FH), 8520 Erlangen Vorrichtung zur entfernung bzw. zur aufweitung von engstellen in koerperfluessigkeit fuehrenden gefaessen
US4456012A (en) * 1982-02-22 1984-06-26 Medtronic, Inc. Iontophoretic and electrical tissue stimulation device
US4417576A (en) * 1982-02-25 1983-11-29 Baran Ostap E Double-wall surgical cuff
US4423725A (en) 1982-03-31 1984-01-03 Baran Ostap E Multiple surgical cuff
US4636195A (en) * 1982-04-02 1987-01-13 Harvey Wolinsky Method and apparatus for removing arterial constriction
DE3214337C2 (de) * 1982-04-19 1984-04-26 Serapharm - Michael Stroetmann, 4400 Münster Resorbierbares Flachmaterial zum Abdichten und Heilen von Wunden und Verfahren zu dessen Herstellung
SU1146057A1 (ru) * 1982-09-17 1985-03-23 Запорожский медицинский институт Эндотрахеальна трубка
SU1069826A1 (ru) * 1982-09-17 1984-01-30 Запорожский медицинский институт Эндотрахеальна трубка
SU1069827A1 (ru) * 1982-09-17 1984-01-30 Запорожский медицинский институт Эндотрахеальна трубка
JPS5967969A (ja) * 1982-10-12 1984-04-17 住友ベークライト株式会社 子宮頚管留置カテ−テル
US4714460A (en) * 1983-07-29 1987-12-22 Reynaldo Calderon Methods and systems for retrograde perfusion in the body for curing it of the disease or immume deficiency
US4582181A (en) * 1983-08-12 1986-04-15 Advanced Cardiovascular Systems, Inc. Steerable dilatation catheter
US4689041A (en) * 1984-01-20 1987-08-25 Eliot Corday Retrograde delivery of pharmacologic and diagnostic agents via venous circulation
US4705507A (en) * 1984-05-02 1987-11-10 Boyles Paul W Arterial catheter means
US4824436A (en) * 1985-04-09 1989-04-25 Harvey Wolinsky Method for the prevention of restenosis
JPH0678460B2 (ja) * 1985-05-01 1994-10-05 株式会社バイオマテリアル・ユニバース 多孔質透明ポリビニルアルユールゲル
JPS61279257A (ja) * 1985-06-05 1986-12-10 林原　健 眉毛発育装置
US4698058A (en) * 1985-10-15 1987-10-06 Albert R. Greenfeld Ultrasonic self-cleaning catheter system for indwelling drains and medication supply
US4733665C2 (en) * 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
JPS62236560A (ja) * 1986-04-09 1987-10-16 テルモ株式会社 血管修復用カテ−テル
SU1410973A1 (ru) * 1986-06-16 1988-07-23 Московский научно-исследовательский институт глазных болезней им.Гельмгольца Способ лечени острой сосудистой патологии глаз
US4767402A (en) * 1986-07-08 1988-08-30 Massachusetts Institute Of Technology Ultrasound enhancement of transdermal drug delivery
US4948587A (en) * 1986-07-08 1990-08-14 Massachusetts Institute Of Technology Ultrasound enhancement of transbuccal drug delivery
US4744366A (en) * 1986-09-10 1988-05-17 Jang G David Concentric independently inflatable/deflatable multiple diameter balloon angioplasty catheter systems and method of use
US4800882A (en) * 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US4787888A (en) * 1987-06-01 1988-11-29 University Of Connecticut Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a)
DE3874440T2 (de) * 1987-07-14 1993-01-28 Sankyo Co Zusammensetzung zur herstellung von antithrombotischen medizinischen erzeugnissen.
JPH03500129A (ja) * 1987-08-28 1991-01-17 リージェンツ・オブ・ザ・ユニバーシティー・オブ・ミネソタ ドラッグデリバリーシステムのための代謝センサー
US4819637A (en) * 1987-09-01 1989-04-11 Interventional Therapeutics Corporation System for artificial vessel embolization and devices for use therewith
US4819751A (en) * 1987-10-16 1989-04-11 Baxter Travenol Laboratories, Inc. Valvuloplasty catheter and method
FR2626476B1 (fr) * 1988-02-01 1997-10-17 Boussignac Georges Sonde destinee a etre introduite a l'interieur d'un corps vivant
DE8904026U1 (de) * 1988-04-20 1989-05-24 Schneider (Europe) Ag, Zuerich, Ch
US4866050A (en) * 1988-04-27 1989-09-12 Ben Amoz Daniel Ultrasonic transdermal application of steroid compositions
JP2683750B2 (ja) * 1988-06-06 1997-12-03 住友電気工業株式会社 カテーテル用バルーン
DE3821544C2 (de) * 1988-06-25 1994-04-28 H Prof Dr Med Just Dilatationskatheter
US5087244A (en) * 1989-01-31 1992-02-11 C. R. Bard, Inc. Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen
DE3915636C1 (de) 1989-05-12 1990-04-26 Sass, Wolfgang, Dr.
US4994033A (en) * 1989-05-25 1991-02-19 Schneider (Usa) Inc. Intravascular drug delivery dilatation catheter
US5007897A (en) * 1989-05-30 1991-04-16 Kalb Irvin M Drug delivery catheter
US5041107A (en) * 1989-10-06 1991-08-20 Cardiac Pacemakers, Inc. Electrically controllable, non-occluding, body implantable drug delivery system
US5016615A (en) * 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
US5236413B1 (en) * 1990-05-07 1996-06-18 Andrew J Feiring Method and apparatus for inducing the permeation of medication into internal tissue
US5120322A (en) * 1990-06-13 1992-06-09 Lathrotec, Inc. Method and apparatus for treatment of fibrotic lesions
EP0533816B1 (de) * 1990-06-15 1995-06-14 Cortrak Medical, Inc. Vorrichtung zur abgabe von medikamenten
US5087243A (en) * 1990-06-18 1992-02-11 Boaz Avitall Myocardial iontophoresis
US5102402A (en) * 1991-01-04 1992-04-07 Medtronic, Inc. Releasable coatings on balloon catheters

Also Published As

Publication number Publication date
EP0533816B1 (de) 1995-06-14
EP0533816A1 (de) 1993-03-31
AU8074591A (en) 1992-01-07
US5628730A (en) 1997-05-13
ATE123658T1 (de) 1995-06-15
JPH05507226A (ja) 1993-10-21
WO1991019529A1 (en) 1991-12-26
US5282785A (en) 1994-02-01
DE69110467T2 (de) 1996-02-01
US5286254A (en) 1994-02-15
CA2081896A1 (en) 1991-12-16

Similar Documents

Publication Publication Date Title
DE69110467D1 (de) Vorrichtung zur abgabe von medikamenten.
ATE284179T1 (de) Implantierbare vorrichtung zur kontrollierten abgabe von arzneimitteln unmittelbar an einen inneren teil des körpers
NO930604L (no) Doseringsform for medikamentavgivelse med tidsvarierende moenster
DE59009462D1 (de) Implantierbare Vorrichtung zur dosierten Abgabe von Medikamenten in den menschlichen Körper.
DE69529173D1 (de) Heterozyklische bizykeln zur behandlung von impotenz
ES2184895T3 (es) Sistema no polimerico de administracion con liberacion retardada.
MXPA03004512A (es) Dispositivos medicos revestidos para la prevencion y el tratamiento de enfermedad vascular.
WO1996004955A3 (en) Polymer matrix drug delivery apparatus and method
DE69840849D1 (de) Doppelwandiger ballonkatheter zur behandlung von proliferativem gewebe
DE69935605D1 (de) Ladung und abgabe von wasser unlöslicher arzneimittel
FI923677A (fi) Foerfarande och anordning foer entydig kombinering av foer en bestaemd behandling avsedda laekemedel med en bestaemd patient
EP1753476A4 (de) Vorläufer-endothelzell-erfassung mit einem arzneimittel abgebenden implantierbaren medizinprodukt
DE69623455D1 (de) Beschichteter dilatator zur abgabe eines arzneistoffs
DE60029926D1 (de) Methoden und geräte zur applikation von substanzen in brustmilchgänge
ES2067324T3 (es) Procedimiento para la obtencion de microparticulas que contienen principio activo, a partir de polimeros degradables por hidrolisis.
ATE207743T1 (de) Pharmazeutische präparate zur gezielten behandlung von morbus crohn und colitis ulcerosa
TR199902438T2 (xx) Bir biyomedikal cihaza g�d�ml� tedavi.
ATE63059T1 (de) Vorrichtung mit zwei schichten zur freisetzung von arzneimitteln.
FR2616330B1 (fr) Agent actif et medicament en contenant destines a prevenir ou a combattre le rejet de greffe d'organe chez l'homme
ATE295731T1 (de) Olanzapine zur behandlung von drogenmissbrauch
ATE116845T1 (de) Dosierungsform zur verabreichung von arzneimitteln für die zirkadiantherapie.
Langer Advances in Chemistry and Their Implications for Studying and Treating Brain Disease
FI864321A (fi) Menetelmä päällystetyn ytimen käsittävän osasen valmistamiseksi
DK0483273T3 (da) Ionoforholdig afgivelsesindretning
Dewart LHRH agonist buserelin: contraception for breast feeding mothers

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee