DE69122494T2 - Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten - Google Patents

Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten

Info

Publication number
DE69122494T2
DE69122494T2 DE69122494T DE69122494T DE69122494T2 DE 69122494 T2 DE69122494 T2 DE 69122494T2 DE 69122494 T DE69122494 T DE 69122494T DE 69122494 T DE69122494 T DE 69122494T DE 69122494 T2 DE69122494 T2 DE 69122494T2
Authority
DE
Germany
Prior art keywords
protein
transdermal application
peptide drugs
peptide
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69122494T
Other languages
English (en)
Other versions
DE69122494D1 (de
Inventor
Hai Bang Lee
Bung Chul Shin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Research Institute of Chemical Technology KRICT
Original Assignee
Korea Research Institute of Chemical Technology KRICT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019890015519A external-priority patent/KR920002264B1/ko
Priority claimed from KR1019900007357A external-priority patent/KR930000062B1/ko
Application filed by Korea Research Institute of Chemical Technology KRICT filed Critical Korea Research Institute of Chemical Technology KRICT
Application granted granted Critical
Publication of DE69122494D1 publication Critical patent/DE69122494D1/de
Publication of DE69122494T2 publication Critical patent/DE69122494T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details
    • A61N1/306Arrangements where at least part of the apparatus is introduced into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DE69122494T 1989-10-27 1991-04-19 Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten Expired - Fee Related DE69122494T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1019890015519A KR920002264B1 (ko) 1989-10-27 1989-10-27 인슐린의 경피투여방법과 그에 사용되는 투여기구
KR1019900007357A KR930000062B1 (ko) 1990-05-22 1990-05-22 단백 및 펩타이드성 약물의 경피투여조성물
EP91106304A EP0509122B1 (de) 1989-10-27 1991-04-19 Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten

Publications (2)

Publication Number Publication Date
DE69122494D1 DE69122494D1 (de) 1996-11-07
DE69122494T2 true DE69122494T2 (de) 1997-02-06

Family

ID=26628108

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69122494T Expired - Fee Related DE69122494T2 (de) 1989-10-27 1991-04-19 Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten

Country Status (6)

Country Link
US (1) US5250023A (de)
EP (3) EP0429842B1 (de)
JP (1) JPH0614980B2 (de)
DE (1) DE69122494T2 (de)
DK (1) DK0509122T3 (de)
ES (1) ES2093652T3 (de)

Families Citing this family (305)

* Cited by examiner, † Cited by third party
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JPS62268570A (ja) * 1986-05-19 1987-11-21 株式会社アドバンス イオントフオレ−ゼ用電極
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AU614092B2 (en) * 1987-09-11 1991-08-22 Paul Max Grinwald Improved method and apparatus for enhanced drug permeation of skin
US4927408A (en) * 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
EP0429842B1 (de) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5084006A (en) * 1990-03-30 1992-01-28 Alza Corporation Iontopheretic delivery device

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Publication number Publication date
EP0509122A1 (de) 1992-10-21
EP0429842B1 (de) 1996-08-28
EP0429842A3 (en) 1992-01-22
EP0509122B1 (de) 1996-10-02
JPH0614980B2 (ja) 1994-03-02
ES2093652T3 (es) 1997-01-01
DK0509122T3 (da) 1996-11-18
EP0727221A3 (de) 1996-10-23
US5250023A (en) 1993-10-05
EP0429842A2 (de) 1991-06-05
JPH03151982A (ja) 1991-06-28
DE69122494D1 (de) 1996-11-07
EP0727221A2 (de) 1996-08-21

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