DE69128530D1 - Zusammengesetztes äquivalent der lebenden haut - Google Patents
Zusammengesetztes äquivalent der lebenden hautInfo
- Publication number
- DE69128530D1 DE69128530D1 DE69128530T DE69128530T DE69128530D1 DE 69128530 D1 DE69128530 D1 DE 69128530D1 DE 69128530 T DE69128530 T DE 69128530T DE 69128530 T DE69128530 T DE 69128530T DE 69128530 D1 DE69128530 D1 DE 69128530D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- skin
- skin equivalent
- collagen
- equivalent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/10—Hair or skin implants
- A61F2/105—Skin implants, e.g. artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
- A61L27/3891—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types as distinct cell layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C12N5/0698—Skin equivalents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/04—Screening or testing on artificial tissues
- C12N2503/06—Screening or testing on artificial skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/08—Collagen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Cardiology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPJ981990 | 1990-04-24 | ||
AUPK430291 | 1991-01-22 | ||
PCT/AU1991/000160 WO1991016010A1 (en) | 1990-04-24 | 1991-04-24 | Composite living skin equivalents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69128530D1 true DE69128530D1 (de) | 1998-02-05 |
DE69128530T2 DE69128530T2 (de) | 1998-08-20 |
Family
ID=25643857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69128530T Expired - Fee Related DE69128530T2 (de) | 1990-04-24 | 1991-04-24 | Zusammengesetztes äquivalent der lebenden haut |
Country Status (15)
Country | Link |
---|---|
US (3) | USRE35399E (de) |
EP (1) | EP0526550B1 (de) |
JP (1) | JPH0747043B2 (de) |
AT (1) | ATE161408T1 (de) |
BR (1) | BR9106354A (de) |
CA (1) | CA2080693C (de) |
DE (1) | DE69128530T2 (de) |
DK (1) | DK0526550T3 (de) |
ES (1) | ES2111566T3 (de) |
FI (1) | FI924773A0 (de) |
GR (1) | GR3026463T3 (de) |
HU (1) | HUT63319A (de) |
RU (1) | RU2135191C1 (de) |
TW (1) | TW225986B (de) |
WO (1) | WO1991016010A1 (de) |
Families Citing this family (136)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5976878A (en) * | 1987-04-28 | 1999-11-02 | The Regents Of The University Of California | Method and apparatus for preparing composite skin replacement |
HUT63319A (en) * | 1990-04-24 | 1993-08-30 | Mark Eisenberg | Method for producing composition equivalent with living skin |
US6399380B1 (en) * | 1991-02-28 | 2002-06-04 | Anti-Cancer, Inc. | Native-state histoculturing skin extracellular support |
US5888720A (en) * | 1992-10-27 | 1999-03-30 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | In vitro micro-organs |
US5610007A (en) * | 1993-01-21 | 1997-03-11 | Universite Laval | Chimeric sheets of epithelial cells |
CA2119064A1 (en) * | 1993-03-17 | 1994-09-18 | Richard A. Berg | Dermal-epidermal in vitro test system |
CH687153A5 (de) * | 1993-12-22 | 1996-09-30 | Jiri E Dr Prenosil | Verfahren und Vorrichtung zur Herstellung einer Zellstruktur auf einer semipermeablen Membran. |
US5489304A (en) * | 1994-04-19 | 1996-02-06 | Brigham & Women's Hospital | Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft |
DE4414755C2 (de) * | 1994-04-27 | 2000-11-16 | Lohmann Therapie Syst Lts | Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung |
JP2858087B2 (ja) * | 1994-09-19 | 1999-02-17 | グンゼ株式会社 | 組織培養用基材及び組織培養法 |
US20030152909A1 (en) * | 1994-11-16 | 2003-08-14 | Mitrani Eduardo N. | In vitro micro-organs, and uses related thereto |
US6080194A (en) * | 1995-02-10 | 2000-06-27 | The Hospital For Joint Disease Orthopaedic Institute | Multi-stage collagen-based template or implant for use in the repair of cartilage lesions |
IT1281870B1 (it) * | 1995-04-27 | 1998-03-03 | Fidia Advanced Biopolymers Srl | Pelle artificiale umana costituita da materiali biocompatibili a base di derivati dell'acido ialuronico |
US20040002772A1 (en) * | 1995-04-28 | 2004-01-01 | Organogenesis, Inc. | Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents |
ATE402994T1 (de) | 1995-11-06 | 2008-08-15 | Mount Sinai Hospital Corp | Rekonstituiertes mineralisiertes knorpelgewebe |
US20020111695A1 (en) * | 1995-11-06 | 2002-08-15 | Mount Sinai Hospital Corporation | Reconstituted mineralized cartilage tissue |
ES2117573B1 (es) * | 1996-07-19 | 1999-02-16 | Comunitario De Transfusion Del | Base dermica especialmente diseñada para el cultivo de queratinocitos. |
WO1998013076A1 (en) * | 1996-09-24 | 1998-04-02 | Brigham And Women's Hospital | Cultured cell-seeded fibrous lattice for tissue replacement |
FR2757635B1 (fr) * | 1996-12-24 | 1999-02-05 | Oreal | Procede d'evaluation des dommages induits dans la peau par les uv-a |
CA2207882A1 (en) * | 1997-06-17 | 1998-12-17 | Joel Claveau | Assessment of human skin damage following exposure to harmful agents |
ES2132027B1 (es) * | 1997-07-04 | 2000-04-01 | Comunitario De Transfusion Del | Desarrollo de una piel artificial mediante cultivo de queratinocitos sobre una base de fibrina y fibroblastos humanos y metodo de preparacion de esta piel para trasplante. |
US7687057B2 (en) * | 1998-01-09 | 2010-03-30 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | In vitro micro-organs, and uses related thereto |
WO1999046285A2 (en) | 1998-03-11 | 1999-09-16 | University Of Southern California | Method of promoting production of living tissue equivalents |
US6432710B1 (en) | 1998-05-22 | 2002-08-13 | Isolagen Technologies, Inc. | Compositions for regenerating tissue that has deteriorated, and methods for using such compositions |
US6177514B1 (en) * | 1999-04-09 | 2001-01-23 | Sulzer Carbomedics Inc. | Blocked functional reagants for cross-linking biological tissues |
FR2792650B1 (fr) * | 1999-04-20 | 2003-02-28 | Oreal | Equivalent de peau agee, son procede de preparation et son utilisation |
US6372494B1 (en) | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
DE19922078A1 (de) * | 1999-05-15 | 2000-11-23 | Weitzel Kage Doris | Gewebekonstrukt für die Transplantationschirurgie |
FR2801313A1 (fr) | 1999-05-19 | 2001-05-25 | Coletica | Produit collagenique contenant du collagene d'origine marine a faible odeur et de preference a proprietes mecaniques ameliorees, ainsi que son utilisation sous forme de compositions ou de produits cosmetiques ou pharmaceutiques |
WO2004006831A2 (en) * | 2002-07-12 | 2004-01-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method and device for inducing biological processes by micro-organs |
FR2798735B1 (fr) * | 1999-09-17 | 2001-11-23 | Serobiologiques Lab Sa | Procede d'evaluation et de suivi du vieillissement tissulaire |
US6479079B1 (en) | 1999-12-13 | 2002-11-12 | Sulzer Carbomedics Inc. | Anticalcification treatments for fixed biomaterials |
FR2809313B1 (fr) * | 2000-05-26 | 2005-11-18 | Coletica | Procedes de preparation de nouveaux supports a base de collagene pour l'ingenieurie tissulaire et biomateriaux obtenus |
US6974679B2 (en) * | 2000-05-26 | 2005-12-13 | Coletica | Support with collagen base for tissue engineering and manufacture of biomaterials |
WO2001091821A1 (fr) * | 2000-05-26 | 2001-12-06 | Coletica | Supports a base de collagene pour l'ingenierie tissulaire et la preparation de biomateriaux |
FR2809412A1 (fr) | 2000-05-26 | 2001-11-30 | Coletica | Utilisation de collagene d'origine aquatique pour la realisation de supports destines a l'ingenierie tissulaire, et supports et biomateriaux obtenus |
US6790454B1 (en) * | 2000-05-26 | 2004-09-14 | Coletica | Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained |
DE10196234B4 (de) * | 2000-05-26 | 2008-04-30 | Engelhard Lyon S.A. | Verfahren zur Herstellung eines Verbundprodukts aus Kollagen für die Gewebebildung und seine Verwendung |
EP1290144A2 (de) * | 2000-05-31 | 2003-03-12 | Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. | In vitro-gewebetestsystem |
DE10026789B4 (de) * | 2000-05-31 | 2004-09-02 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Knorpelersatz und Verfahren zu dessen Herstellung |
JP4751005B2 (ja) * | 2000-05-31 | 2011-08-17 | フラウンホファー ゲセルシャフト ツール フェールデルンク ダー アンゲヴァンテン フォルシュンク エー.ファオ. | 三次元皮膚モデル |
US6638709B2 (en) * | 2000-12-27 | 2003-10-28 | Ortec International, Inc. | Processes for making cryopreserved composite living constructs and products resulting therefrom |
US6500464B2 (en) * | 2000-12-28 | 2002-12-31 | Ortec International, Inc. | Bilayered collagen construct |
US6974697B2 (en) * | 2001-03-02 | 2005-12-13 | Stratech Corporation | Skin substitutes with improved barrier function |
NZ549527A (en) * | 2001-03-02 | 2008-04-30 | Stratatech Corp | Improved skin substitutes and uses thereof |
EP1273913A1 (de) * | 2001-07-02 | 2003-01-08 | Cognis France S.A. | Verfahren zur Bestimmung der Interaktionen zwischen Keratinocyten und Neuronen |
US7468242B2 (en) * | 2001-11-05 | 2008-12-23 | Medgenics, Inc. | Dermal micro organs, methods and apparatuses for producing and using the same |
US8088568B2 (en) | 2001-11-05 | 2012-01-03 | Medgentics, Inc. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8501396B2 (en) | 2001-11-05 | 2013-08-06 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8394371B2 (en) * | 2002-02-11 | 2013-03-12 | Neocutis Sa | Compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same |
AU2003219830A1 (en) * | 2002-02-22 | 2003-09-09 | Ebi, L.P. | Methods and compositions for treating bone or cartilage defects |
US7741116B2 (en) * | 2002-03-06 | 2010-06-22 | University Of Cincinnati | Surgical device for skin therapy or testing |
KR100874543B1 (ko) * | 2002-04-22 | 2008-12-16 | 동아제약주식회사 | 인공피부 배양물 및 그 제조방법 |
EP1549738B1 (de) * | 2002-04-30 | 2010-04-21 | Stratatech Corporation | Exogene angiogene wachstumsfaktoren exprimierende keratinozyten |
US7229820B2 (en) * | 2002-06-13 | 2007-06-12 | Wilson Wolf Manufacturing Corporation | Apparatus and method for culturing and preserving tissue constructs |
AU2003243781A1 (en) * | 2002-06-24 | 2004-01-06 | Amniotech, Inc. | Amniotic membrane mediated delivery of bioactive molecules |
AU2003254298A1 (en) * | 2002-08-02 | 2004-02-23 | Stratatech Corporation | Species specific dna detection |
US7666134B2 (en) * | 2002-09-28 | 2010-02-23 | Kci Licensing, Inc. | System and method for transplantation of dermal tissue |
US20050107876A1 (en) * | 2002-09-30 | 2005-05-19 | Kim Ki-Ho | Dermal substitute consisting of amnion and biodegradable polymer, the preparation method and the use thereof |
US7177705B2 (en) * | 2003-02-19 | 2007-02-13 | Stimu-Heal Inc. | Surface electrode for electrical stimulation of tissue |
JP4097544B2 (ja) * | 2003-02-27 | 2008-06-11 | 独立行政法人理化学研究所 | 人工リンパ節 |
EP2377403A1 (de) * | 2003-05-01 | 2011-10-19 | Medgenics, Inc. | Genetisch modifizierter dermisches mikroorgan-ausdrückender Faktor VIII |
CA2534349C (en) | 2003-08-01 | 2012-04-10 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
US7375077B2 (en) * | 2003-09-19 | 2008-05-20 | The Board Of Trustees Of The University Of Illinois | In vivo synthesis of connective tissues |
DE102004039537A1 (de) * | 2004-08-13 | 2006-02-23 | Phenion Gmbh & Co. Kg | Vernetzte Kollagenmatrix zur Herstellung eines Hautäquivalentes |
US20060058238A1 (en) * | 2004-09-15 | 2006-03-16 | Lee Laurent-Applegate | Fetal skin cell protein compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same |
AU2006218610B2 (en) | 2005-03-01 | 2011-01-20 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
AU2006227752B2 (en) | 2005-03-17 | 2010-10-21 | Stratatech Corporation | Skin substitutes with improved purity |
WO2006107188A1 (en) | 2005-04-06 | 2006-10-12 | Fujifilm Manufacturing Europe B.V. | A non-porous film for culturing cells |
WO2006107207A2 (en) * | 2005-04-06 | 2006-10-12 | Fujifilm Manufacturing Europe B.V. | A non-porous film for culturing cells |
FR2889808B1 (fr) | 2005-08-17 | 2011-07-22 | Oreal | Utilisation de l'acide 8-hexadecene-1,16-dicarboxylique comme agent de soin destine a favoriser la cohesion de la couche cornee |
WO2007029676A1 (ja) * | 2005-09-07 | 2007-03-15 | Arblast Co., Ltd. | 生体組織シート及びその作製方法 |
EP1998787A4 (de) * | 2006-03-03 | 2010-04-21 | Organogenesis Inc | Wiederherstellung und reparatur von oralem gewebe |
US8454948B2 (en) | 2006-09-14 | 2013-06-04 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
AU2007294858B2 (en) | 2006-09-14 | 2011-05-12 | Medgenics Medical Israel, Ltd | Long lasting drug formulations |
US8709081B2 (en) | 2006-10-23 | 2014-04-29 | Stemedica Cell Technologies, Inc. | Cellular scaffold |
US8105380B2 (en) * | 2006-10-23 | 2012-01-31 | Stemedica Cell Technologies, Inc. | Cellular scaffold |
US20080260794A1 (en) * | 2007-02-12 | 2008-10-23 | Lauritzen Nels J | Collagen products and methods for producing collagen products |
US9056151B2 (en) * | 2007-02-12 | 2015-06-16 | Warsaw Orthopedic, Inc. | Methods for collagen processing and products using processed collagen |
DE102007026639A1 (de) | 2007-06-06 | 2008-12-11 | Stefan-Andreas Ulrich | Industrielle Fertigung tierischer Lederhautsubstitute für die Lederproduktion aus etablierten Epithelzelllinien und/oder primären Epithelzellkulturen, wie vorzugsweise Fibroplasten, Melanozyten, Keratiozyten sowie deren Verfahren und Vorrichtungen |
US20090145087A1 (en) | 2007-11-14 | 2009-06-11 | Stratatech Corporation | Cold storage of organotypically cultured skin equivalents for clinical applications |
US9308068B2 (en) | 2007-12-03 | 2016-04-12 | Sofradim Production | Implant for parastomal hernia |
US9382514B2 (en) | 2008-06-20 | 2016-07-05 | Escape Therapeutics, Inc. | Compositions comprising mesenchymal stem cell-derived fibroblasts |
US9242026B2 (en) | 2008-06-27 | 2016-01-26 | Sofradim Production | Biosynthetic implant for soft tissue repair |
PT2352472T (pt) | 2008-11-04 | 2017-04-11 | Stratatech Corp | Equivalentes de pele secos e irradiados prontos a utilizar |
DE102009022351A1 (de) * | 2009-05-15 | 2010-11-25 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Modulares Produktionssystem zur automatischen Herstellung von dreidimensionalen Gewebestrukturen |
DE102009022349B4 (de) * | 2009-05-15 | 2011-02-03 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Automatisches Trennen von Gewebeschichten |
WO2010135655A2 (en) | 2009-05-21 | 2010-11-25 | Stratatech Corporation | Human skin substitutes expressing il-12 |
FR2949688B1 (fr) | 2009-09-04 | 2012-08-24 | Sofradim Production | Tissu avec picots revetu d'une couche microporeuse bioresorbable |
AU2011219882A1 (en) | 2010-02-23 | 2012-07-12 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for preparing human melanocytes from human pluripotent stem cells |
GB201003656D0 (en) * | 2010-03-05 | 2010-04-21 | Tigenix Ltd | Fabrication process |
US8790699B2 (en) | 2010-04-23 | 2014-07-29 | Warsaw Orthpedic, Inc. | Foam-formed collagen strand |
US8460691B2 (en) | 2010-04-23 | 2013-06-11 | Warsaw Orthopedic, Inc. | Fenestrated wound repair scaffold |
PT2573167T (pt) * | 2010-05-21 | 2019-12-10 | Rodrigo Focion Soto Pareja | Processo para a produção de emplastros ou curativos de pele autóloga através de cultivo de queratinócitos e fibroblastos autólogos com soro autólogo para a geração de pele |
JP2013532152A (ja) | 2010-06-15 | 2013-08-15 | メドジェニクス・メディカル・イスラエル・リミテッド | 長期持続性の医薬製剤 |
WO2011160055A2 (en) * | 2010-06-18 | 2011-12-22 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Hair follicle neogenesis |
FR2967163A1 (fr) | 2010-11-05 | 2012-05-11 | Centre Nat Rech Scient | Procede in vitro ou ex vivo pour la maintenance en survie et la generation ou reconstruction d'un epiderme |
JP6031221B2 (ja) * | 2011-03-02 | 2016-11-24 | 花王株式会社 | 皮膚感作性物質の評価方法 |
FR2972626B1 (fr) | 2011-03-16 | 2014-04-11 | Sofradim Production | Prothese comprenant un tricot tridimensionnel et ajoure |
JP5868601B2 (ja) * | 2011-03-23 | 2016-02-24 | フタムラ化学株式会社 | 液体培地用足場部材 |
JP2012205516A (ja) * | 2011-03-29 | 2012-10-25 | Osaka Univ | 人工皮膚モデルの製造方法、及び人工皮膚モデル |
RU2464987C1 (ru) * | 2011-04-07 | 2012-10-27 | Российская Федерация, от имени которой выступает Министерство образования и науки РФ | Способ получения резорбируемой полилактидной матрицы для культивирования и имплантации клеток, предназначенных для заживления ран |
FR2976001B1 (fr) | 2011-05-30 | 2014-10-31 | Oreal | Modele de cuir chevelu reconstruit et procede de screening de molecules actives |
FR2977789B1 (fr) | 2011-07-13 | 2013-07-19 | Sofradim Production | Prothese pour hernie ombilicale |
FR2977790B1 (fr) | 2011-07-13 | 2013-07-19 | Sofradim Production | Prothese pour hernie ombilicale |
GB201112922D0 (en) | 2011-07-27 | 2011-09-14 | Univ Durham | Micro-organ |
JP2014528264A (ja) | 2011-09-30 | 2014-10-27 | ソフラディム・プロダクション | 軽重量メッシュの可逆性硬さ |
FR2985271B1 (fr) | 2011-12-29 | 2014-01-24 | Sofradim Production | Tricot a picots |
FR2985170B1 (fr) | 2011-12-29 | 2014-01-24 | Sofradim Production | Prothese pour hernie inguinale |
FR2994185B1 (fr) | 2012-08-02 | 2015-07-31 | Sofradim Production | Procede de preparation d’une couche poreuse a base de chitosane |
FR2995779B1 (fr) | 2012-09-25 | 2015-09-25 | Sofradim Production | Prothese comprenant un treillis et un moyen de consolidation |
FR2995778B1 (fr) | 2012-09-25 | 2015-06-26 | Sofradim Production | Prothese de renfort de la paroi abdominale et procede de fabrication |
FR2995788B1 (fr) | 2012-09-25 | 2014-09-26 | Sofradim Production | Patch hemostatique et procede de preparation |
EP2900174B1 (de) | 2012-09-28 | 2017-04-12 | Sofradim Production | Verpackung für eine bruchoperationsvorrichtung |
WO2014160000A1 (en) | 2013-03-13 | 2014-10-02 | Stratatech Corporation | Cryopreservation of viable human skin substitutes |
CA2910328C (en) | 2013-05-03 | 2019-10-22 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Skin substitutes and methods for hair follicle neogenesis |
FR3006578B1 (fr) | 2013-06-07 | 2015-05-29 | Sofradim Production | Prothese a base d’un textile pour voie laparoscopique |
FR3006581B1 (fr) | 2013-06-07 | 2016-07-22 | Sofradim Production | Prothese a base d’un textile pour voie laparoscopique |
EP3000432B1 (de) | 2014-09-29 | 2022-05-04 | Sofradim Production | Textilbasierte Prothese für die Behandlung von Leistenbruch |
EP3000433B1 (de) | 2014-09-29 | 2022-09-21 | Sofradim Production | Vorrichtung zur Einführung einer Prothese zur Hernie-Behandlung in einen Einschnitt und flexible textile Prothese |
WO2016080732A1 (ko) * | 2014-11-17 | 2016-05-26 | 주식회사 바이오코즈글로벌코리아 | 세포 배양 배지, 표피성장인자 및 소혈청알부민을 포함하는 피부 상태 개선용 화장료 조성물 |
EP3029189B1 (de) | 2014-12-05 | 2021-08-11 | Sofradim Production | Prothetisches poröses Netz, sein Herstellungsverfahren und Hernienprothese |
EP3059255B1 (de) | 2015-02-17 | 2020-05-13 | Sofradim Production | Verfahren zur Herstellung einer Matrix auf Chitosanbasis mit faseroptischem Verstärkungselement |
EP3085337B1 (de) | 2015-04-24 | 2022-09-14 | Sofradim Production | Prothese zur unterstützung einer bruststruktur |
EP3106185B1 (de) | 2015-06-19 | 2018-04-25 | Sofradim Production | Synthetische prothese mit einem gewirk und einem nichtporösen film und verfahren zur formung davon |
EP3195830B1 (de) | 2016-01-25 | 2020-11-18 | Sofradim Production | Prothese zur hernienreparatur |
TW201803982A (zh) * | 2016-06-24 | 2018-02-01 | 資生堂股份有限公司 | 三維培養皮膚片、用於製造其之細胞培養容器及其製造方法 |
FR3054449B1 (fr) | 2016-07-29 | 2018-08-31 | L'oreal | Equivalent de peau a compartiments dermiques juxtaposes distincts |
EP3312325B1 (de) | 2016-10-21 | 2021-09-22 | Sofradim Production | Verfahren zur herstellung eines netzes mit einem daran befestigten nahtmaterial mit widerhaken und dadurch erhaltenes netz |
EP3398554A1 (de) | 2017-05-02 | 2018-11-07 | Sofradim Production | Prothese zur leistenbruch-reparatur |
FR3071512B1 (fr) | 2017-09-28 | 2022-02-25 | Oreal | Signatures moleculaires de trois sous-populations de fibroblastes dermiques et equivalent de derme comprenant une de ces sous-populations |
EP3653171A1 (de) | 2018-11-16 | 2020-05-20 | Sofradim Production | Implantate zur weichgewebereparatur |
IT201800010390A1 (it) * | 2018-11-16 | 2020-05-16 | Diego Furlan | Dispositivo medico monouso per la medicazione di lesioni della pelle di un paziente e relativi procedimenti di preparazione e utilizzazione |
FR3108505A1 (fr) * | 2020-03-30 | 2021-10-01 | Universite Grenoble Alpes | Biomatériau comprenant une matrice poreuse résorbable et procédé de fabrication associé |
FR3111904B1 (fr) | 2020-06-30 | 2022-10-21 | Oreal | Bioencre pour bioimpression d’un modèle de jonction dermo-épidermique invaginée |
WO2022056131A2 (en) * | 2020-09-11 | 2022-03-17 | The Trustees Of Columbia University In The City Of New York | Wearable engineered human skin and systems and methods for making the same |
Family Cites Families (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4144126A (en) * | 1975-05-21 | 1979-03-13 | Beecham Group Limited | Cell culture method |
US4060081A (en) * | 1975-07-15 | 1977-11-29 | Massachusetts Institute Of Technology | Multilayer membrane useful as synthetic skin |
US4280954A (en) * | 1975-07-15 | 1981-07-28 | Massachusetts Institute Of Technology | Crosslinked collagen-mucopolysaccharide composite materials |
US4016036A (en) * | 1975-11-14 | 1977-04-05 | Massachusetts Institute Of Technology | Process for serially culturing keratinocytes |
US4024020A (en) * | 1975-12-15 | 1977-05-17 | Monsanto Company | Method of cell culture on polyacrylonitrile surface |
DE2557870A1 (de) * | 1975-12-22 | 1977-06-23 | Linde Ag | Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen |
US4117881A (en) * | 1977-06-14 | 1978-10-03 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | System for and method of freezing biological tissue |
US4135975A (en) * | 1977-12-14 | 1979-01-23 | Lichtman Marshall A | Obtaining human cell lines that elaborate colony stimulating activity for marrow cells of man and other species and methods of preparing same |
US4228243A (en) * | 1978-07-13 | 1980-10-14 | Toray Industries, Inc. | Cell culture propagation apparatus |
US4299819A (en) * | 1979-01-02 | 1981-11-10 | Sloan-Kettering Institute For Cancer Research | Process for treating burn victims |
FR2461002A1 (fr) * | 1979-07-13 | 1981-01-30 | Inst Nat Sante Rech Med | Procede pour stimuler la croissance des cellules d'epiderme humain et produits faisant application dudit procede |
US4342828A (en) * | 1979-07-20 | 1982-08-03 | Morinaga Milk Industry Co., Ltd. | Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells |
US4412947A (en) * | 1979-09-12 | 1983-11-01 | Seton Company | Collagen sponge |
US4254226A (en) * | 1979-09-13 | 1981-03-03 | Sloan Kettering Institute For Cancer Research | Process for growing human epidermal cells in tissue culture |
US4642292A (en) * | 1979-10-29 | 1987-02-10 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method for isolation of connective tissue biomatrix |
US4352887A (en) * | 1979-10-29 | 1982-10-05 | Albert Einstein College Of Medicine Of Yeshiva University | Method and article for culturing differentiated cells |
US4304866A (en) * | 1979-11-14 | 1981-12-08 | Massachusetts Institute Of Technology | Transplantable sheets of living keratinous tissue |
US4522753A (en) * | 1980-07-17 | 1985-06-11 | Massachusetts Institute Of Technology | Method for preserving porosity in porous materials |
US4481946A (en) * | 1980-08-14 | 1984-11-13 | Altshuler John H | Bone marrow transplant method and apparatus |
US4486188A (en) * | 1980-08-14 | 1984-12-04 | Applied Medical Devices, Inc. | Bone marrow transplant method and apparatus |
US4314380A (en) * | 1980-09-26 | 1982-02-09 | Koken Co., Ltd. | Artificial bone |
US4565784A (en) * | 1981-01-26 | 1986-01-21 | Trustees Of Boston University | Hydrogels capable of supporting cell growth |
US4553272A (en) * | 1981-02-26 | 1985-11-19 | University Of Pittsburgh | Regeneration of living tissues by growth of isolated cells in porous implant and product thereof |
US4546500A (en) * | 1981-05-08 | 1985-10-15 | Massachusetts Institute Of Technology | Fabrication of living blood vessels and glandular tissues |
US4489710A (en) * | 1981-06-23 | 1984-12-25 | Xoma Corporation | Composition and method for transplantation therapy |
US4350629A (en) * | 1981-07-29 | 1982-09-21 | Massachusetts Institute Of Technology | Procedures for preparing composite materials from collagen and glycosaminoglycan |
US4621100A (en) * | 1981-09-25 | 1986-11-04 | The Upjohn Company | Treatment of osteoporosis with prostaglandins |
US4418691A (en) * | 1981-10-26 | 1983-12-06 | Massachusetts Institute Of Technology | Method of promoting the regeneration of tissue at a wound |
US4505266A (en) * | 1981-10-26 | 1985-03-19 | Massachusetts Institute Of Technology | Method of using a fibrous lattice |
US4458678A (en) * | 1981-10-26 | 1984-07-10 | Massachusetts Institute Of Technology | Cell-seeding procedures involving fibrous lattices |
FR2517315B1 (fr) * | 1981-11-30 | 1985-12-20 | Tech Cuir Centre | Procede de preparation de formes nouvelles de collagene, natif ou dereticule, a structure helicoidale preservee, associees a des mucopolysaccharides et leurs applications notamment dans les domaines cosmetologiques, pharmaceutiques, analytiques et autres |
US4485096A (en) * | 1982-02-26 | 1984-11-27 | Massachusetts Institute Of Technology | Tissue-equivalent and method for preparation thereof |
US4520821A (en) * | 1982-04-30 | 1985-06-04 | The Regents Of The University Of California | Growing of long-term biological tissue correction structures in vivo |
US4485097A (en) * | 1982-05-26 | 1984-11-27 | Massachusetts Institute Of Technology | Bone-equivalent and method for preparation thereof |
JPS5928472A (ja) * | 1982-08-09 | 1984-02-15 | Koken:Kk | 細胞培養用基質およびこの基質を用いた細胞培養・分離法 |
US4645669A (en) * | 1982-10-04 | 1987-02-24 | Albert Einstein College Of Medicine Of Yeshiva University | Culturing and emplacement of differentiated cells in vivo |
US4960423A (en) * | 1982-11-17 | 1990-10-02 | Smith Donald W | Method of enhancing the attachment of endothelial cells on a matrix and vascular prosthesis with enhanced anti-thrombogenic characteristics |
US4769317A (en) * | 1983-06-14 | 1988-09-06 | Hefton John M | Process for growing human epidermis, product thereof |
US5000963A (en) * | 1983-06-14 | 1991-03-19 | Hefton John M | Method of treating the skin using human epidermal sheets |
US4673649A (en) * | 1983-07-15 | 1987-06-16 | University Patents, Inc. | Process and defined medium for growth of human epidermal keratinocyte cells |
US4940666A (en) * | 1983-07-15 | 1990-07-10 | University Patents, Inc. | Process and defined medium for growth of human epidermal keratinocyte cells |
US4448718A (en) * | 1983-09-13 | 1984-05-15 | Massachusetts Institute Of Technology | Method for the preparation of collagen-glycosaminoglycan composite materials |
US4609551A (en) * | 1984-03-20 | 1986-09-02 | Arnold Caplan | Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites |
US4925924A (en) * | 1984-03-27 | 1990-05-15 | University Of Medicine And Dentistry Of New Jersey | Biocompatible synthetic and collagen compositions having a dual-type porosity for treatment of wounds and pressure ulcers and therapeutic methods thereof |
CA1295796C (en) * | 1984-03-27 | 1992-02-18 | Conrad Whyne | Biodegradable matrix and methods for producing same |
JPS60261460A (ja) * | 1984-06-11 | 1985-12-24 | 株式会社 高研 | コラ−ゲンとポリ―α―アミノ酸膜から成る人工皮膚 |
US4604346A (en) * | 1984-10-09 | 1986-08-05 | Massachusetts Institute Of Technology | Skin-equivalent prepared by the use of punch biopsy |
JPS61253065A (ja) * | 1985-05-02 | 1986-11-10 | 片倉チツカリン株式会社 | キトサン誘導体およびコラ−ゲンの複合材の医用材料およびその製造法 |
US4963489A (en) * | 1987-04-14 | 1990-10-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
JPS62246371A (ja) * | 1986-04-19 | 1987-10-27 | 株式会社 高研 | 人工皮膚及びその製造方法 |
FR2612938B1 (fr) * | 1987-03-26 | 1989-06-23 | Cird | Procede d'obtention d'un equivalent de peau et equivalent de peau correspondant |
FR2612939B1 (fr) * | 1987-03-26 | 1989-06-23 | Cird | Equivalent de peau |
US4835102A (en) * | 1987-03-31 | 1989-05-30 | Eugene Bell | Tissue equivalent test systems |
ATE86115T1 (de) * | 1987-04-28 | 1993-03-15 | Univ California | Vorrichtung und verfahren zur herstellung eines komposithautersatzes. |
US5273900A (en) * | 1987-04-28 | 1993-12-28 | The Regents Of The University Of California | Method and apparatus for preparing composite skin replacement |
US4975377A (en) * | 1987-05-14 | 1990-12-04 | Key Marc E | Cell growth chambers and method of use thereof |
US4888291A (en) * | 1987-06-19 | 1989-12-19 | President And Fellows Of Harvard College | Human epithelium originating from cell cultures |
GB8721018D0 (en) * | 1987-09-07 | 1987-10-14 | Alcan Int Ltd | Porous inorganic membrane support |
US5015584A (en) * | 1987-10-14 | 1991-05-14 | Board Of Regents, The University Of Texas System | Epidermal graft system |
US4837379A (en) * | 1988-06-02 | 1989-06-06 | Organogenesis Inc. | Fibrin-collagen tissue equivalents and methods for preparation thereof |
US4950483A (en) * | 1988-06-30 | 1990-08-21 | Collagen Corporation | Collagen wound healing matrices and process for their production |
JPH0271749A (ja) * | 1988-09-07 | 1990-03-12 | Terumo Corp | 人工皮膚 |
US4996154A (en) * | 1989-05-04 | 1991-02-26 | Millipore Corporation | Method for growing cellular tissue |
NL8902237A (nl) * | 1989-09-06 | 1991-04-02 | Hc Implants Bv | Kunsthuid. |
HUT63319A (en) * | 1990-04-24 | 1993-08-30 | Mark Eisenberg | Method for producing composition equivalent with living skin |
-
1991
- 1991-04-24 HU HU9203338A patent/HUT63319A/hu unknown
- 1991-04-24 US US08/346,525 patent/USRE35399E/en not_active Expired - Lifetime
- 1991-04-24 CA CA002080693A patent/CA2080693C/en not_active Expired - Fee Related
- 1991-04-24 BR BR919106354A patent/BR9106354A/pt not_active Application Discontinuation
- 1991-04-24 RU RU92016420A patent/RU2135191C1/ru not_active IP Right Cessation
- 1991-04-24 ES ES91908747T patent/ES2111566T3/es not_active Expired - Lifetime
- 1991-04-24 EP EP91908747A patent/EP0526550B1/de not_active Expired - Lifetime
- 1991-04-24 US US07/777,419 patent/US5282859A/en not_active Ceased
- 1991-04-24 DK DK91908747T patent/DK0526550T3/da active
- 1991-04-24 JP JP3508090A patent/JPH0747043B2/ja not_active Expired - Fee Related
- 1991-04-24 DE DE69128530T patent/DE69128530T2/de not_active Expired - Fee Related
- 1991-04-24 AT AT91908747T patent/ATE161408T1/de not_active IP Right Cessation
- 1991-04-24 WO PCT/AU1991/000160 patent/WO1991016010A1/en active IP Right Grant
- 1991-10-21 TW TW080108276A patent/TW225986B/zh active
-
1992
- 1992-10-21 FI FI924773A patent/FI924773A0/fi not_active Application Discontinuation
-
1996
- 1996-02-16 US US08/602,271 patent/US6039760A/en not_active Expired - Fee Related
-
1998
- 1998-03-27 GR GR980400647T patent/GR3026463T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI924773A (fi) | 1992-10-21 |
HUT63319A (en) | 1993-08-30 |
ES2111566T3 (es) | 1998-03-16 |
ATE161408T1 (de) | 1998-01-15 |
DK0526550T3 (da) | 1998-08-31 |
EP0526550B1 (de) | 1997-12-29 |
RU2135191C1 (ru) | 1999-08-27 |
HU9203338D0 (en) | 1993-01-28 |
FI924773A0 (fi) | 1992-10-21 |
TW225986B (de) | 1994-07-01 |
WO1991016010A1 (en) | 1991-10-31 |
DE69128530T2 (de) | 1998-08-20 |
JPH0747043B2 (ja) | 1995-05-24 |
US6039760A (en) | 2000-03-21 |
GR3026463T3 (en) | 1998-06-30 |
EP0526550A4 (en) | 1993-06-30 |
AU7756991A (en) | 1991-11-11 |
JPH05506169A (ja) | 1993-09-16 |
EP0526550A1 (de) | 1993-02-10 |
US5282859A (en) | 1994-02-01 |
AU632693B2 (en) | 1993-01-07 |
USRE35399E (en) | 1996-12-10 |
CA2080693A1 (en) | 1991-10-25 |
CA2080693C (en) | 2001-11-27 |
BR9106354A (pt) | 1993-04-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69128530D1 (de) | Zusammengesetztes äquivalent der lebenden haut | |
RU92016420A (ru) | Композиционные эквиваленты живой кожи, способ его получения, тест-набор | |
Stern et al. | Histologic study of artificial skin used in the treatment of full-thickness thermal injury | |
De Vries et al. | Reduced wound contraction and scar formation in punch biopsy wounds. Native collagen dermal substitutes. A clinical study | |
Chick | Brief history and biology of skin grafting | |
Cohen et al. | Models of wound healing | |
IL123077A0 (en) | Device and method for repairing a dermal defect | |
De Vries et al. | Dermal substitutes for full‐thickness wounds in a one‐stage grafting model | |
Hafemann et al. | Cross-linking by 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC) of a collagen/elastin membrane meant to be used as a dermal substitute: effects on physical, biochemical and biological features in vitro | |
Moriyama et al. | Development of composite cultured oral mucosa utilizing collagen sponge matrix and contracted collagen gel: a preliminary study for clinical applications | |
DE3788231D1 (de) | Kosmetisches mittel und zusammensetzung zur behandlung der haut. | |
Matsui et al. | Histological evaluation of skin reconstruction using artificial dermis | |
ATE175242T1 (de) | Ein gewebekulturverfahren für haut im natürlichen zustand | |
Lafrance et al. | Study of the tensile properties of living skin equivalents | |
Eisinger | Regeneration of epidermis by cells grown in tissue culture | |
MY131052A (en) | Composite living skin equivalents | |
DE50100859D1 (de) | Hautmatrix zur Abdeckung und Regenerierung verletzter Hautpartien sowie Verfahren zu ihrer Herstellung | |
Banes et al. | Biologic, biosynthetic, and synthetic dressings as temporary wound covers: a biochemical comparison | |
Betz et al. | The immunohistochemical analysis of fibronectin, collagen type III, laminin, and cytokeratin 5 in putrified skin | |
NO924034L (no) | Komposittmateriale ekvivalent til levende hud | |
Naughton et al. | Synthetic biodegradable polymer scaffolds | |
Fleming et al. | A simple immunochemical technique for distinguishing melanocytes and melanophages in paraffin‐embedded tissue | |
Bell et al. | Tissue fabrication: Reconstitution and remodeling in vitro | |
Morykwas | Physicochemical investigations of a new collagen based burn dressing | |
della Sanità | Pellegrini, Graziella 2, 3; Ranno, Rosario 2, 4; Stracuzzi, Giorgio 2, 4; Bondanza, Sergio 3; Guerra, Liliana 3; Zambruno, Giovanna 5; Micali, Giovanni 4; De Luca, Michele 3, 6 Author Information Laboratory of Tissue Engineering and Laboratory of Molecular and Cellular Biology, IDI, Istituto Dermopatico dell'Immacolata, Rome, Italy, and Burn Unit Ospedale Cannizzaro and Department of Plastic Surgery, University of |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8365 | Fully valid after opposition proceedings | ||
8339 | Ceased/non-payment of the annual fee |