DE69132138T2 - Polyanhydride aus oligomerisierten ungesättigten aliphatischen säuren - Google Patents
Polyanhydride aus oligomerisierten ungesättigten aliphatischen säurenInfo
- Publication number
- DE69132138T2 DE69132138T2 DE69132138T DE69132138T DE69132138T2 DE 69132138 T2 DE69132138 T2 DE 69132138T2 DE 69132138 T DE69132138 T DE 69132138T DE 69132138 T DE69132138 T DE 69132138T DE 69132138 T2 DE69132138 T2 DE 69132138T2
- Authority
- DE
- Germany
- Prior art keywords
- polyanhydrides
- unsaturated aliphatic
- aliphatic acids
- oligomerized unsaturated
- oligomerized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
- C08G67/04—Polyanhydrides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
- C08G67/02—Copolymers of carbon monoxide and aliphatic unsaturated compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/467,635 US5171812A (en) | 1990-01-19 | 1990-01-19 | Polyanhydrides of oligomerized unsaturated aliphatic acids |
PCT/US1991/000126 WO1991010696A1 (en) | 1990-01-19 | 1991-01-07 | Polyanhydrides of the oligomerized unsaturated aliphatic acids |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69132138D1 DE69132138D1 (de) | 2000-05-31 |
DE69132138T2 true DE69132138T2 (de) | 2000-09-21 |
Family
ID=23856493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69132138T Expired - Fee Related DE69132138T2 (de) | 1990-01-19 | 1991-01-07 | Polyanhydride aus oligomerisierten ungesättigten aliphatischen säuren |
Country Status (11)
Country | Link |
---|---|
US (1) | US5171812A (de) |
EP (1) | EP0511292B1 (de) |
JP (1) | JP3126141B2 (de) |
KR (1) | KR920703685A (de) |
AT (1) | ATE192174T1 (de) |
AU (1) | AU637883B2 (de) |
DE (1) | DE69132138T2 (de) |
IE (1) | IE910100A1 (de) |
NZ (1) | NZ236807A (de) |
WO (1) | WO1991010696A1 (de) |
ZA (1) | ZA91381B (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5843089A (en) | 1990-12-28 | 1998-12-01 | Boston Scientific Corporation | Stent lining |
US5660851A (en) * | 1989-12-26 | 1997-08-26 | Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem | Ocular inserts |
US5317079A (en) * | 1990-01-19 | 1994-05-31 | Nova Pharmaceutical Corporation | Fatty acid terminated polyanhydride |
US5175235A (en) * | 1990-06-04 | 1992-12-29 | Nova Pharmaceutical Corporation | Branched polyanhydrides |
US5197882A (en) * | 1990-05-14 | 1993-03-30 | Gary R. Jernberg | Periodontal barrier and method for aiding periodontal tissue regeneration agents |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5473103A (en) * | 1993-12-16 | 1995-12-05 | Yissum Research Development Co. Of The Hebrew University Of Jerusalem | Biopolymers derived from hydrolyzable diacid fats |
US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
US5622166A (en) * | 1995-04-24 | 1997-04-22 | Dura Pharmaceuticals, Inc. | Dry powder inhaler delivery system |
US6303134B1 (en) | 1996-08-29 | 2001-10-16 | Advanced Research And Technology Institute, Inc. | Pharmacotherapeutic process and composition for central nervous system disorders |
US20030220234A1 (en) | 1998-11-02 | 2003-11-27 | Selvaraj Naicker | Deuterated cyclosporine analogs and their use as immunodulating agents |
US6503528B1 (en) | 1999-11-19 | 2003-01-07 | Abbott Laboratories | Polymeric compositions and a method of making the same |
WO2001080830A2 (en) * | 2000-04-21 | 2001-11-01 | Advanced Research And Technology Institute, Inc. | Pharmacotherapeutic process and composition for central nervous system disorders |
US6506408B1 (en) * | 2000-07-13 | 2003-01-14 | Scimed Life Systems, Inc. | Implantable or insertable therapeutic agent delivery device |
US7749539B2 (en) * | 2000-11-30 | 2010-07-06 | Efrat Biopolymers Ltd. | Polymeric formulations for drug delivery |
IL140017A (en) * | 2000-11-30 | 2009-09-22 | Abraham J Domb | Polyhedra |
EP1429819B1 (de) | 2001-09-24 | 2010-11-24 | Boston Scientific Limited | Optimierte dosierung bei paclitaxelhaltigen stents |
NZ531944A (en) | 2001-10-19 | 2006-03-31 | Isotechnika Inc | Synthesis of cyclosporin analogs |
US7306580B2 (en) * | 2003-04-16 | 2007-12-11 | Cook Incorporated | Medical device with therapeutic agents |
US7662864B2 (en) | 2003-06-04 | 2010-02-16 | Rutgers, The State University Of New Jersey | Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent |
ES2345108T3 (es) * | 2003-07-01 | 2010-09-15 | Mayo Foundation For Medical Education And Research | Macromeros a base de fumarato injertado con hidroxiapatita para composites biodegradables. |
WO2006071813A2 (en) * | 2004-12-23 | 2006-07-06 | Massachusetts Institute Of Technology | Disposable medical supplies from hydrolytically biodegradable plastics |
GB2433122B (en) | 2005-12-10 | 2008-07-23 | Endet Ltd | Gas sampling probe |
US20070162110A1 (en) * | 2006-01-06 | 2007-07-12 | Vipul Bhupendra Dave | Bioabsorbable drug delivery devices |
WO2015191742A1 (en) | 2014-06-13 | 2015-12-17 | Rutgers, The State University Of New Jersey | Process and intermediates for preparing poly(anhydride-esters) |
WO2016097848A1 (en) | 2014-12-18 | 2016-06-23 | Dexcel Pharma Technologies Ltd. | Alternating and semi-alternating poly(ester-anhydride) copolymers |
AU2017406466A1 (en) | 2017-03-29 | 2019-10-17 | Dexcel Pharma Technologies Ltd. | Compositions comprising biodegradable copolymers |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4757128A (en) * | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
US4888176A (en) * | 1984-05-21 | 1989-12-19 | Massachusetts Institute Of Technology | Controlled drug delivery high molecular weight polyanhydrides |
US4886870A (en) * | 1984-05-21 | 1989-12-12 | Massachusetts Institute Of Technology | Bioerodible articles useful as implants and prostheses having predictable degradation rates |
US4891225A (en) * | 1984-05-21 | 1990-01-02 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
CH671402A5 (de) * | 1985-10-02 | 1989-08-31 | Sandoz Ag | |
US4789724A (en) * | 1986-10-17 | 1988-12-06 | Massachusetts Institute Of Technology | Preparation of anhydride copolymers |
US5019379A (en) * | 1987-07-31 | 1991-05-28 | Massachusetts Institute Of Technology | Unsaturated polyanhydrides |
US4857311A (en) * | 1987-07-31 | 1989-08-15 | Massachusetts Institute Of Technology | Polyanhydrides with improved hydrolytic degradation properties |
US4916204A (en) * | 1987-07-31 | 1990-04-10 | Massachusetts Institute Of Technology | Pure polyanhydride from dicarboxylic acid and coupling agent |
-
1990
- 1990-01-19 US US07/467,635 patent/US5171812A/en not_active Expired - Lifetime
-
1991
- 1991-01-07 AT AT91903474T patent/ATE192174T1/de not_active IP Right Cessation
- 1991-01-07 AU AU72257/91A patent/AU637883B2/en not_active Ceased
- 1991-01-07 EP EP91903474A patent/EP0511292B1/de not_active Expired - Lifetime
- 1991-01-07 DE DE69132138T patent/DE69132138T2/de not_active Expired - Fee Related
- 1991-01-07 KR KR1019920701687A patent/KR920703685A/ko active IP Right Grant
- 1991-01-07 WO PCT/US1991/000126 patent/WO1991010696A1/en active IP Right Grant
- 1991-01-07 JP JP03503553A patent/JP3126141B2/ja not_active Expired - Fee Related
- 1991-01-11 IE IE010091A patent/IE910100A1/en not_active Application Discontinuation
- 1991-01-17 NZ NZ236807A patent/NZ236807A/en unknown
- 1991-01-18 ZA ZA91381A patent/ZA91381B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
KR920703685A (ko) | 1992-12-18 |
IE910100A1 (en) | 1991-07-31 |
AU7225791A (en) | 1991-08-05 |
US5171812A (en) | 1992-12-15 |
WO1991010696A1 (en) | 1991-07-25 |
JP3126141B2 (ja) | 2001-01-22 |
NZ236807A (en) | 1992-07-28 |
DE69132138D1 (de) | 2000-05-31 |
EP0511292A1 (de) | 1992-11-04 |
EP0511292B1 (de) | 2000-04-26 |
ZA91381B (en) | 1992-02-26 |
AU637883B2 (en) | 1993-06-10 |
JPH05505632A (ja) | 1993-08-19 |
ATE192174T1 (de) | 2000-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |