DE69132289D1 - Proanthocyanidinpolymere mit antivirales aktivität und deren herstellungsverfahren - Google Patents

Proanthocyanidinpolymere mit antivirales aktivität und deren herstellungsverfahren

Info

Publication number
DE69132289D1
DE69132289D1 DE69132289T DE69132289T DE69132289D1 DE 69132289 D1 DE69132289 D1 DE 69132289D1 DE 69132289 T DE69132289 T DE 69132289T DE 69132289 T DE69132289 T DE 69132289T DE 69132289 D1 DE69132289 D1 DE 69132289D1
Authority
DE
Germany
Prior art keywords
polymers
antiviral activity
proanthocyanidine
production method
proanthocyanidin polymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69132289T
Other languages
English (en)
Inventor
S Tempesta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shaman Pharmaceuticals Inc
Original Assignee
Shaman Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shaman Pharmaceuticals Inc filed Critical Shaman Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69132289D1 publication Critical patent/DE69132289D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
DE69132289T 1990-10-12 1991-10-10 Proanthocyanidinpolymere mit antivirales aktivität und deren herstellungsverfahren Expired - Lifetime DE69132289D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59689390A 1990-10-12 1990-10-12
US07/737,077 US5211944A (en) 1990-10-12 1991-07-29 Proanthocyanidin polymers having antiviral activity and methods of obtaining same
PCT/US1991/007679 WO1992006695A1 (en) 1990-10-12 1991-10-10 Proanthocyanidin polymers having antiviral activity and methods of obtaining same

Publications (1)

Publication Number Publication Date
DE69132289D1 true DE69132289D1 (de) 2000-08-10

Family

ID=27082674

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132289T Expired - Lifetime DE69132289D1 (de) 1990-10-12 1991-10-10 Proanthocyanidinpolymere mit antivirales aktivität und deren herstellungsverfahren

Country Status (12)

Country Link
US (2) US5211944A (de)
EP (1) EP0553253B1 (de)
JP (1) JP3448052B2 (de)
KR (1) KR100207949B1 (de)
AT (1) ATE194288T1 (de)
AU (1) AU660631B2 (de)
CA (1) CA2093825C (de)
DE (1) DE69132289D1 (de)
MX (1) MX9101540A (de)
NZ (1) NZ240200A (de)
SG (1) SG52707A1 (de)
WO (1) WO1992006695A1 (de)

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US6774141B1 (en) 1992-03-31 2004-08-10 The United States Of America As Represented By The Secretary Of Health And Human Services Calanolide and related antiviral compounds, compositions, and uses thereof
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US5892060A (en) * 1994-08-03 1999-04-06 Sarawak Medichem Pharmaceuticals, Inc. Method for the preparation of (+)-calanolide a and analogues thereof
US5977385A (en) * 1994-08-03 1999-11-02 Sarawak Medichem Pharmaceuticals Method for the preparation of (+)-calanolide A and analogues thereof
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JPH1059846A (ja) * 1996-06-10 1998-03-03 Kikkoman Corp 白内障の予防または治療薬剤
AU4988197A (en) * 1996-10-16 1998-05-11 Shaman Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer antidiarrheal compo sitions
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US5968973A (en) * 1996-11-18 1999-10-19 Cancer Institute (Hospital), Chinese Academy Of Medical Sciences Method for treating hyperplasia
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ES2318874T3 (es) 1997-09-09 2009-05-01 Rutgers, The State University Of New Jersey Extracto de proantocianidina vegetal eficaz para inhibir la adherencia a superficies de bacterias con fimbrias de tipo p.
US6060235A (en) * 1997-09-19 2000-05-09 Geltex Pharmaceuticals, Inc. Antiviral polymers comprising acid functional groups and hydrophobic groups
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WO2000064903A2 (en) 1999-04-26 2000-11-02 Sarawak Medichem Pharmaceuticals, Inc. Methods for preparing antiviral calanolide compounds
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US7208183B2 (en) * 2002-10-05 2007-04-24 Bobrowski Paul J Methods and preparations of the latex from the croton species
ES2536713T3 (es) * 2003-03-12 2015-05-27 Epitome Pharmaceuticals Limited Composiciones para la piel lipófilas de rápida absorción y usos de las mismas
FR2852842A1 (fr) * 2003-03-31 2004-10-01 Silab Sa Procede de preparation d'un principe actif a partir d'exsudat de resine des fruits de daemonorops draco, compositions l'incluant et utilisations
US20050074510A1 (en) * 2003-10-04 2005-04-07 Bobrowski Paul J. Topical preparations for use in treatment of anorectal disease
US20050207983A1 (en) 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
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JP2005314316A (ja) * 2004-04-30 2005-11-10 Kikkoman Corp 抗ｓａｒｓコロナウイルス剤
US20070065486A1 (en) * 2004-05-21 2007-03-22 Migco Limited Migraine remedy
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CN105640925B (zh) 2010-08-30 2019-08-16 普马特里克斯营业公司 干燥粉末配方及用于治疗肺部疾病的方法
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Also Published As

Publication number Publication date
US5211944A (en) 1993-05-18
JP3448052B2 (ja) 2003-09-16
EP0553253B1 (de) 2000-07-05
KR100207949B1 (ko) 1999-07-15
CA2093825A1 (en) 1992-04-13
KR930702010A (ko) 1993-09-08
EP0553253A1 (de) 1993-08-04
SG52707A1 (en) 1998-09-28
AU8878091A (en) 1992-05-20
AU660631B2 (en) 1995-07-06
US5494661A (en) 1996-02-27
MX9101540A (es) 1992-06-05
CA2093825C (en) 2003-01-07
NZ240200A (en) 1994-04-27
WO1992006695A1 (en) 1992-04-30
JPH06502413A (ja) 1994-03-17
EP0553253A4 (en) 1993-09-15
ATE194288T1 (de) 2000-07-15

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