DE69215612T2 - Verzögerte Freigabe-Matrix für Arzneimittel - Google Patents

Verzögerte Freigabe-Matrix für Arzneimittel

Info

Publication number
DE69215612T2
DE69215612T2 DE69215612T DE69215612T DE69215612T2 DE 69215612 T2 DE69215612 T2 DE 69215612T2 DE 69215612 T DE69215612 T DE 69215612T DE 69215612 T DE69215612 T DE 69215612T DE 69215612 T2 DE69215612 T2 DE 69215612T2
Authority
DE
Germany
Prior art keywords
drugs
release matrix
matrix
delayed release
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69215612T
Other languages
English (en)
Other versions
DE69215612D1 (de
Inventor
Thinnayam N Krishnamurthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of DE69215612D1 publication Critical patent/DE69215612D1/de
Publication of DE69215612T2 publication Critical patent/DE69215612T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/15—Suppositories
DE69215612T 1991-09-11 1992-04-15 Verzögerte Freigabe-Matrix für Arzneimittel Expired - Lifetime DE69215612T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/758,883 US5215758A (en) 1991-09-11 1991-09-11 Controlled release matrix suppository for pharmaceuticals

Publications (2)

Publication Number Publication Date
DE69215612D1 DE69215612D1 (de) 1997-01-16
DE69215612T2 true DE69215612T2 (de) 1997-05-15

Family

ID=25053475

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69215612T Expired - Lifetime DE69215612T2 (de) 1991-09-11 1992-04-15 Verzögerte Freigabe-Matrix für Arzneimittel
DE69230475T Expired - Lifetime DE69230475T2 (de) 1991-09-11 1992-04-15 Verzögerte Freigabe Matrix für Arzneimittel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69230475T Expired - Lifetime DE69230475T2 (de) 1991-09-11 1992-04-15 Verzögerte Freigabe Matrix für Arzneimittel

Country Status (13)

Country Link
US (2) US5215758A (de)
EP (2) EP0531611B1 (de)
JP (2) JP3034125B2 (de)
KR (2) KR100203339B1 (de)
AT (2) ATE145820T1 (de)
AU (1) AU653048B2 (de)
CA (1) CA2065210C (de)
DE (2) DE69215612T2 (de)
DK (2) DK0531611T3 (de)
ES (2) ES2097826T3 (de)
GR (1) GR3022572T3 (de)
IL (2) IL101758A (de)
ZA (1) ZA923417B (de)

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US5773025A (en) * 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
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US5662933A (en) * 1993-09-09 1997-09-02 Edward Mendell Co., Inc. Controlled release formulation (albuterol)
KR100354702B1 (ko) 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
US5554379A (en) * 1994-06-20 1996-09-10 Kv Pharmaceutical Company Long acting GI and esophageal protectant
US5670163A (en) * 1994-06-20 1997-09-23 Kv Pharmaceuticals Company Long acting GI and esophageal protectant
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Also Published As

Publication number Publication date
ATE145820T1 (de) 1996-12-15
DK0698389T3 (da) 2000-05-01
JP3624123B2 (ja) 2005-03-02
DE69230475T2 (de) 2000-07-13
KR100225493B1 (en) 1999-10-15
CA2065210C (en) 2000-08-29
IL117356A (en) 2000-08-31
DE69215612D1 (de) 1997-01-16
JP2000136149A (ja) 2000-05-16
DK0531611T3 (da) 1997-05-26
KR100203339B1 (ko) 1999-06-15
CA2065210A1 (en) 1993-03-12
DE69230475D1 (de) 2000-01-27
GR3022572T3 (en) 1997-05-31
IL101758A (en) 1996-12-05
IL117356A0 (en) 1996-07-23
EP0531611A1 (de) 1993-03-17
AU2107392A (en) 1993-03-18
ZA923417B (en) 1993-01-27
IL101758A0 (en) 1992-12-30
ES2097826T3 (es) 1997-04-16
US5215758A (en) 1993-06-01
EP0698389A1 (de) 1996-02-28
JPH05148159A (ja) 1993-06-15
AU653048B2 (en) 1994-09-15
ES2139798T3 (es) 2000-02-16
JP3034125B2 (ja) 2000-04-17
EP0531611B1 (de) 1996-12-04
KR930005616A (ko) 1993-04-20
US5508043A (en) 1996-04-16
EP0698389B1 (de) 1999-12-22
ATE187887T1 (de) 2000-01-15

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