DE69215925D1 - Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz - Google Patents

Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz

Info

Publication number
DE69215925D1
DE69215925D1 DE69215925T DE69215925T DE69215925D1 DE 69215925 D1 DE69215925 D1 DE 69215925D1 DE 69215925 T DE69215925 T DE 69215925T DE 69215925 T DE69215925 T DE 69215925T DE 69215925 D1 DE69215925 D1 DE 69215925D1
Authority
DE
Germany
Prior art keywords
chemiluminescence
electro
measurement
immunoreactive substances
immunoreactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69215925T
Other languages
English (en)
Other versions
DE69215925T2 (de
Inventor
Akira Shibue
Masaru Tanaka
Shinji Kamiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TDK Corp
Original Assignee
TDK Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TDK Corp filed Critical TDK Corp
Application granted granted Critical
Publication of DE69215925D1 publication Critical patent/DE69215925D1/de
Publication of DE69215925T2 publication Critical patent/DE69215925T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
DE69215925T 1991-02-19 1992-02-18 Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz Expired - Fee Related DE69215925T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4605491 1991-02-19
JP3206336A JPH0534345A (ja) 1991-02-19 1991-07-23 化学発光を利用する抗原・抗体の測定方法

Publications (2)

Publication Number Publication Date
DE69215925D1 true DE69215925D1 (de) 1997-01-30
DE69215925T2 DE69215925T2 (de) 1997-05-22

Family

ID=26386168

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69215925T Expired - Fee Related DE69215925T2 (de) 1991-02-19 1992-02-18 Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz

Country Status (4)

Country Link
US (1) US5240863A (de)
EP (1) EP0500305B1 (de)
JP (1) JPH0534345A (de)
DE (1) DE69215925T2 (de)

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US6140045A (en) 1995-03-10 2000-10-31 Meso Scale Technologies Multi-array, multi-specific electrochemiluminescence testing
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US6200531B1 (en) 1998-05-11 2001-03-13 Igen International, Inc. Apparatus for carrying out electrochemiluminescence test measurements
AU2003200956B2 (en) * 1998-05-11 2006-01-19 Bioveris Corporation Improved Apparatus and Methods for Carrying Out Electrochemiluminescence Test Measurements
GB0103765D0 (en) * 2001-02-15 2001-04-04 Affitech As Assay
CA2764307C (en) 2001-06-29 2015-03-03 Meso Scale Technologies, Llc. Assay plates, reader systems and methods for luminescence test measurements
ATE471369T1 (de) 2001-07-30 2010-07-15 Meso Scale Technologies Llc Assay-elektroden mit schichten aus immobilisiertem lipid/protein sowie verfahren zu deren herstellung und verwendung
AU2002333526B2 (en) 2001-09-10 2008-01-17 Meso Scale Technologies, Llc. Methods and apparatus for conducting multiple measurements on a sample
CA2493905A1 (en) 2002-06-20 2003-12-31 Sudeep M. Kumar Electrochemiluminescence flow cell and flow cell components
KR100434690B1 (ko) * 2002-07-19 2004-06-04 소광섭 생명체에 대한 자기장의 영향을 측정하는 장치 및 방법
US7000870B2 (en) * 2002-11-07 2006-02-21 Aerion Corporation Laminar flow wing for transonic cruise
EP1893990B1 (de) * 2005-06-03 2018-05-02 Board of Regents of the University of Texas System Elektrochemie und elektrogenerierte chemolumineszenz mit einer faradayschen einzelelektrode
US20100261292A1 (en) 2009-04-10 2010-10-14 Meso Scale Technologies, Llc Methods for Conducting Assays
US20110143947A1 (en) * 2009-07-27 2011-06-16 Meso Scale Technologies, Llc Assay Apparatuses, Consumables and Methods
WO2012051386A2 (en) 2010-10-14 2012-04-19 Meso Scale Technologies, Llc Reagent storage in an assay device
ES2581553T3 (es) 2010-10-25 2016-09-06 F. Hoffmann-La Roche Ag Utilización de compuestos potenciadores de la señal en la detección electroquimioluminiscente
EP3467500B1 (de) 2011-11-11 2021-05-12 Eli N. Glezer Durch co-binder unterstützte testverfahren
JP6416785B2 (ja) 2013-01-04 2018-10-31 メソ スケール テクノロジーズ エルエルシー マルチウェルプレートおよびコンタクトプラットフォームを利用した電気化学発光分析用計器
EP4219750A3 (de) 2013-03-11 2023-12-13 Meso Scale Technologies, LLC. Verbesserte verfahren zur durchführung von multiplex-assays
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
KR102257912B1 (ko) 2013-03-13 2021-05-27 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
US10202500B2 (en) 2013-03-15 2019-02-12 Lubrizol Advanced Materials, Inc. Heavy metal free CPVC compounds
US10955412B2 (en) 2014-05-09 2021-03-23 Meso Scale Technologies, Llc. Graphene-modified electrodes
JP6695280B2 (ja) 2014-05-15 2020-05-20 メソ スケール テクノロジーズ エルエルシー 改善されたアッセイ方法
WO2016091755A1 (en) 2014-12-08 2016-06-16 F. Hoffmann-La Roche Ag Method for measurement of vitamin d
CN108698047B (zh) 2016-03-11 2022-04-01 豪夫迈·罗氏有限公司 电化学发光检测中的支链胺
CN106124753B (zh) * 2016-07-08 2018-03-06 广州东林生物科技有限公司 电化学发光缓冲液及清洗液
US11686013B2 (en) 2018-02-23 2023-06-27 Meso Scale Technologies, Llc. Methods of screening antigen-binding molecules by normalizing for the concentration of antigen-binding molecule
EP3793715A2 (de) 2018-05-17 2021-03-24 Meso Scale Technologies, LLC Verfahren zur isolierung von oberflächenmarkerindikatoren
US20210382043A1 (en) 2018-10-23 2021-12-09 Meso Scale Technologies, Llc. Methods for isolating surface marker displaying agents
KR20210146884A (ko) 2019-01-03 2021-12-06 메소 스케일 테크놀러지즈, 엘엘시 검정 측정 수행용 조성물 및 방법
CN114144422A (zh) 2019-03-01 2022-03-04 中尺度技术有限责任公司 用于免疫方法的被电化学发光标记的探针、使用这类探针的方法和包含这类探针的试剂盒
KR20220005571A (ko) 2019-06-07 2022-01-13 에프. 호프만-라 로슈 아게 전부 lna 올리고뉴클레오티드 혼성화
EP4154008A1 (de) 2020-05-19 2023-03-29 Meso Scale Technologies, LLC Verfahren, zusammensetzungen und kits zum nachweis von nukleinsäuren
KR20230042471A (ko) 2020-07-01 2023-03-28 메소 스케일 테크놀러지즈, 엘엘시 검정 측정을 위한 조성물 및 방법
CA3193739A1 (en) 2020-09-02 2022-03-10 Meso Scale Technologies, Llc. Kits for detecting one or more target analytes in a sample and methods of making and using the same
WO2022051481A2 (en) 2020-09-04 2022-03-10 Meso Scale Technologies, Llc. Methods for isolating central nervous system surface marker displaying agents
EP4267961A1 (de) 2020-12-22 2023-11-01 F. Hoffmann-La Roche AG Verfahren zum nachweis eines analyten von interesse in einer probe
EP4302089A1 (de) 2021-03-01 2024-01-10 Meso Scale Technologies, LLC System und verfahren zur durchführung eines multiplex-tests
EP4330672A1 (de) 2021-04-26 2024-03-06 Meso Scale Technologies, LLC. Verfahren zur isolierung und analyse eines zielanalyts, das von einem oberflächenmarker-anzeigemittel eingekapselt ist
WO2023129884A1 (en) 2021-12-30 2023-07-06 Meso Scale Technologies, Llc. Methods for electrochemiluminescence detection
WO2023156510A1 (en) 2022-02-18 2023-08-24 F. Hoffmann-La Roche Ag Method for detecting an analyte of interest in a sample
WO2023212315A2 (en) 2022-04-29 2023-11-02 Meso Scale Technologies, Llc. Methods for detecting and isolating extracellular vesicles

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US4181650A (en) * 1975-08-25 1980-01-01 Maier Charles L Jr Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids
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US4280815A (en) * 1979-06-18 1981-07-28 Technicon Instruments Corporation Electrochemiluminescent immunoassay and apparatus therefor
AU9094982A (en) * 1982-02-01 1983-08-11 Miles Laboratories Inc. Photogenic labels to alleviate quenching in immuno assays
JPH0678985B2 (ja) * 1987-03-06 1994-10-05 ティーディーケイ株式会社 電気化学的光学特性検出用電極および電気化学的光学特性検出方法
ZA898290B (en) * 1988-11-03 1991-06-26 Igen Inc Electrochemiluminescent assays
JPH03107746A (ja) * 1989-09-21 1991-05-08 Tdk Corp 電気化学発光検出用容器

Also Published As

Publication number Publication date
EP0500305B1 (de) 1996-12-18
DE69215925T2 (de) 1997-05-22
JPH0534345A (ja) 1993-02-09
US5240863A (en) 1993-08-31
EP0500305A2 (de) 1992-08-26
EP0500305A3 (en) 1992-12-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8320 Willingness to grant licences declared (paragraph 23)
8339 Ceased/non-payment of the annual fee