DE69215925T2 - Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz - Google Patents
Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-ChemilumineszenzInfo
- Publication number
- DE69215925T2 DE69215925T2 DE69215925T DE69215925T DE69215925T2 DE 69215925 T2 DE69215925 T2 DE 69215925T2 DE 69215925 T DE69215925 T DE 69215925T DE 69215925 T DE69215925 T DE 69215925T DE 69215925 T2 DE69215925 T2 DE 69215925T2
- Authority
- DE
- Germany
- Prior art keywords
- chemiluminescence
- electro
- measurement
- immunoreactive substances
- immunoreactive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4605491 | 1991-02-19 | ||
| JP3206336A JPH0534345A (ja) | 1991-02-19 | 1991-07-23 | 化学発光を利用する抗原・抗体の測定方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69215925D1 DE69215925D1 (de) | 1997-01-30 |
| DE69215925T2 true DE69215925T2 (de) | 1997-05-22 |
Family
ID=26386168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69215925T Expired - Fee Related DE69215925T2 (de) | 1991-02-19 | 1992-02-18 | Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5240863A (de) |
| EP (1) | EP0500305B1 (de) |
| JP (1) | JPH0534345A (de) |
| DE (1) | DE69215925T2 (de) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5779976A (en) * | 1988-11-03 | 1998-07-14 | Igen International, Inc. | Apparatus for improved luminescence assays |
| ZA92803B (en) | 1991-02-06 | 1992-11-25 | Igen Inc | Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets |
| GB9225354D0 (en) * | 1992-12-04 | 1993-01-27 | Univ Manchester | Immunoassay |
| US5993740A (en) * | 1995-01-20 | 1999-11-30 | Hitachi, Ltd. | Immunoassay method and analyzer using magnetic particles |
| US6207369B1 (en) * | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| US6066448A (en) * | 1995-03-10 | 2000-05-23 | Meso Sclae Technologies, Llc. | Multi-array, multi-specific electrochemiluminescence testing |
| US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| AU2003200956B2 (en) * | 1998-05-11 | 2006-01-19 | Bioveris Corporation | Improved Apparatus and Methods for Carrying Out Electrochemiluminescence Test Measurements |
| AU2006201608B2 (en) * | 1998-05-11 | 2007-06-07 | Bioveris Corporation | Improved Apparatus and Methods for Carrying Out Electrochemiluminescence Test Measurements |
| US6200531B1 (en) * | 1998-05-11 | 2001-03-13 | Igen International, Inc. | Apparatus for carrying out electrochemiluminescence test measurements |
| GB0103765D0 (en) * | 2001-02-15 | 2001-04-04 | Affitech As | Assay |
| JP2004534226A (ja) | 2001-06-29 | 2004-11-11 | メソ スケイル テクノロジーズ，エルエルシー | 発光試験測定用のアッセイプレート、リーダシステム及び方法 |
| DK1412487T3 (da) | 2001-07-30 | 2010-08-30 | Meso Scale Technologies Llc | Assayelektroder der har immobiliserede lipid/proteinlag og fremgangsmåder til at fremstille og anvende disse |
| US7858321B2 (en) | 2001-09-10 | 2010-12-28 | Meso Scale Technologies, Llc | Methods and apparatus for conducting multiple measurements on a sample |
| US7553448B2 (en) | 2002-06-20 | 2009-06-30 | Bioveris Corporation | Electrochemiluminescence flow cell and flow cell components |
| KR100434690B1 (ko) * | 2002-07-19 | 2004-06-04 | 소광섭 | 생명체에 대한 자기장의 영향을 측정하는 장치 및 방법 |
| US7000870B2 (en) * | 2002-11-07 | 2006-02-21 | Aerion Corporation | Laminar flow wing for transonic cruise |
| ES2675044T3 (es) | 2005-06-03 | 2018-07-06 | Board Of Regents Of The University Of Texas System | Electroquímica y quimioluminiscencia electrogenerada con un único electrodo faradaico |
| US20100261292A1 (en) | 2009-04-10 | 2010-10-14 | Meso Scale Technologies, Llc | Methods for Conducting Assays |
| EP3611510A1 (de) | 2009-07-27 | 2020-02-19 | Meso Scale Technologies, LLC | Assay-vorrichtungen, -verbrauchsmittel und -verfahren |
| US20120157332A1 (en) | 2010-10-14 | 2012-06-21 | Meso Scale Technologies, Llc | Reagent Storage in an Assay Device |
| CA2813089C (en) | 2010-10-25 | 2018-02-20 | F. Hoffmann-La Roche Ag | Use of signal enhancing compounds in electrochemiluminescence detection |
| EP2776833B1 (de) | 2011-11-11 | 2018-09-05 | Eli N. Glezer | Cobinder-unterstützte testverfahren |
| EP4345460A2 (de) | 2013-01-04 | 2024-04-03 | Meso Scale Technologies, LLC. | Testvorrichtungen, verfahren und reagenzien |
| WO2014164594A1 (en) | 2013-03-11 | 2014-10-09 | Meso Scale Technologies, Llc. | Improved methods for conducting multiplexed assays |
| KR102257912B1 (ko) | 2013-03-13 | 2021-05-27 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| WO2014143623A1 (en) | 2013-03-15 | 2014-09-18 | The Lubrizol Corporation | Heavy metal free cpvc compositions |
| CA2947747C (en) | 2014-05-09 | 2024-03-05 | Meso Scale Technologies, Llc. | Graphene-modified electrodes |
| US10408823B2 (en) | 2014-05-15 | 2019-09-10 | Meso Scale Technologies, Llc. | Assay methods |
| JP6602884B2 (ja) | 2014-12-08 | 2019-11-06 | エフ．ホフマン−ラ ロシュ アーゲー | ビタミンｄの測定法 |
| CN108698047B (zh) | 2016-03-11 | 2022-04-01 | 豪夫迈·罗氏有限公司 | 电化学发光检测中的支链胺 |
| CN106124753B (zh) * | 2016-07-08 | 2018-03-06 | 广州东林生物科技有限公司 | 电化学发光缓冲液及清洗液 |
| FI3756009T3 (fi) | 2018-02-23 | 2023-12-01 | Meso Scale Technologies Llc | Menetelmiä antigeeniä sitovien molekyylien seulontaan normalisoimalla antigeeniä sitovan molekyylin pitoisuus |
| WO2019222708A2 (en) | 2018-05-17 | 2019-11-21 | Meso Scale Technologies, Llc. | Methods for isolating surface marker displaying agents |
| WO2020086751A1 (en) | 2018-10-23 | 2020-04-30 | Meso Scale Technologies, Llc. | Methods for isolating surface marker displaying agents |
| CN113366313A (zh) | 2019-01-03 | 2021-09-07 | 中尺度技术有限责任公司 | 实施分析测量的组合物及方法 |
| JP2022522480A (ja) | 2019-03-01 | 2022-04-19 | メソ スケール テクノロジーズ エルエルシー | 免疫測定法で使用するための電気化学発光標識プローブ、当該プローブを使用する方法および該プローブを含むキット |
| WO2020245377A1 (en) | 2019-06-07 | 2020-12-10 | F. Hoffmann-La Roche Ag | Hybridizing all-lna oligonucleotides |
| WO2021236584A1 (en) | 2020-05-19 | 2021-11-25 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for nucleic acid detection |
| AU2021299536A1 (en) | 2020-07-01 | 2023-02-16 | Meso Scale Technologies, Llc. | Compositions and methods for assay measurements |
| WO2022051485A2 (en) | 2020-09-02 | 2022-03-10 | Meso Scale Technologies,Llc. | Kits for detecting one or more target analytes in a sample and methods of making and using the same |
| WO2022051481A2 (en) | 2020-09-04 | 2022-03-10 | Meso Scale Technologies, Llc. | Methods for isolating central nervous system surface marker displaying agents |
| WO2022136234A1 (en) | 2020-12-22 | 2022-06-30 | F. Hoffmann-La Roche Ag | Method for detecting an analyte of interest in a sample |
| CA3212325A1 (en) | 2021-03-01 | 2022-09-09 | Meso Scale Technologies, Llc. | System and method for conducting a multiplexed assay |
| WO2022231900A1 (en) | 2021-04-26 | 2022-11-03 | Meso Scale Technologies, Llc. | Methods for isolating and analyzing a target analyte encapsulated by a surface marker displaying agent |
| WO2023129884A1 (en) | 2021-12-30 | 2023-07-06 | Meso Scale Technologies, Llc. | Methods for electrochemiluminescence detection |
| WO2023156510A1 (en) | 2022-02-18 | 2023-08-24 | F. Hoffmann-La Roche Ag | Method for detecting an analyte of interest in a sample |
| WO2023212315A2 (en) | 2022-04-29 | 2023-11-02 | Meso Scale Technologies, Llc. | Methods for detecting and isolating extracellular vesicles |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4041146A (en) * | 1975-05-01 | 1977-08-09 | General Electric Company | Method for detection of biological particles |
| US4181650A (en) * | 1975-08-25 | 1980-01-01 | Maier Charles L Jr | Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids |
| AU531777B2 (en) * | 1978-04-05 | 1983-09-08 | Syva Co. | Label/solid conjugate immunoassay system |
| US4280815A (en) * | 1979-06-18 | 1981-07-28 | Technicon Instruments Corporation | Electrochemiluminescent immunoassay and apparatus therefor |
| AU9094982A (en) * | 1982-02-01 | 1983-08-11 | Miles Laboratories Inc. | Photogenic labels to alleviate quenching in immuno assays |
| JPH0678985B2 (ja) * | 1987-03-06 | 1994-10-05 | ティーディーケイ株式会社 | 電気化学的光学特性検出用電極および電気化学的光学特性検出方法 |
| ZA898290B (en) * | 1988-11-03 | 1991-06-26 | Igen Inc | Electrochemiluminescent assays |
| JPH03107746A (ja) * | 1989-09-21 | 1991-05-08 | Tdk Corp | 電気化学発光検出用容器 |
-
1991
- 1991-07-23 JP JP3206336A patent/JPH0534345A/ja active Pending
-
1992
- 1992-02-18 EP EP92301295A patent/EP0500305B1/de not_active Expired - Lifetime
- 1992-02-18 DE DE69215925T patent/DE69215925T2/de not_active Expired - Fee Related
- 1992-02-19 US US07/836,740 patent/US5240863A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5240863A (en) | 1993-08-31 |
| EP0500305A2 (de) | 1992-08-26 |
| EP0500305A3 (en) | 1992-12-02 |
| JPH0534345A (ja) | 1993-02-09 |
| DE69215925D1 (de) | 1997-01-30 |
| EP0500305B1 (de) | 1996-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8320 | Willingness to grant licences declared (paragraph 23) | ||
| 8339 | Ceased/non-payment of the annual fee |