DE69215925T2 - Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz - Google Patents

Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz

Info

Publication number
DE69215925T2
DE69215925T2 DE69215925T DE69215925T DE69215925T2 DE 69215925 T2 DE69215925 T2 DE 69215925T2 DE 69215925 T DE69215925 T DE 69215925T DE 69215925 T DE69215925 T DE 69215925T DE 69215925 T2 DE69215925 T2 DE 69215925T2
Authority
DE
Germany
Prior art keywords
chemiluminescence
electro
measurement
immunoreactive substances
immunoreactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69215925T
Other languages
English (en)
Other versions
DE69215925D1 (de
Inventor
Akira Shibue
Masaru Tanaka
Shinji Kamiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TDK Corp
Original Assignee
TDK Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TDK Corp filed Critical TDK Corp
Application granted granted Critical
Publication of DE69215925D1 publication Critical patent/DE69215925D1/de
Publication of DE69215925T2 publication Critical patent/DE69215925T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
DE69215925T 1991-02-19 1992-02-18 Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz Expired - Fee Related DE69215925T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4605491 1991-02-19
JP3206336A JPH0534345A (ja) 1991-02-19 1991-07-23 化学発光を利用する抗原・抗体の測定方法

Publications (2)

Publication Number Publication Date
DE69215925D1 DE69215925D1 (de) 1997-01-30
DE69215925T2 true DE69215925T2 (de) 1997-05-22

Family

ID=26386168

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69215925T Expired - Fee Related DE69215925T2 (de) 1991-02-19 1992-02-18 Verfahren zur Messung von immunoreaktiven Substanzen mit Elektro-Chemilumineszenz

Country Status (4)

Country Link
US (1) US5240863A (de)
EP (1) EP0500305B1 (de)
JP (1) JPH0534345A (de)
DE (1) DE69215925T2 (de)

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US6200531B1 (en) * 1998-05-11 2001-03-13 Igen International, Inc. Apparatus for carrying out electrochemiluminescence test measurements
AU2006201608B2 (en) * 1998-05-11 2007-06-07 Bioveris Corporation Improved Apparatus and Methods for Carrying Out Electrochemiluminescence Test Measurements
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US7842246B2 (en) 2001-06-29 2010-11-30 Meso Scale Technologies, Llc Assay plates, reader systems and methods for luminescence test measurements
AU2002365119A1 (en) 2001-07-30 2003-09-04 Meso Scale Technologies, Llc. Assay electrodes having immobilized lipid/protein layers and methods of making and using the same
EP2405019A1 (de) 2001-09-10 2012-01-11 Meso Scale Technologies LLC Verfahren, Reagenzien, Kits und Vorrichtung zur Proteinfunktionsanalyse
EP1552284A4 (de) 2002-06-20 2008-11-05 Bioveris Corp Elektrochemilumineszenzstr mungszelle und strömungszellenkomponenten
KR100434690B1 (ko) * 2002-07-19 2004-06-04 소광섭 생명체에 대한 자기장의 영향을 측정하는 장치 및 방법
US7000870B2 (en) * 2002-11-07 2006-02-21 Aerion Corporation Laminar flow wing for transonic cruise
KR101385384B1 (ko) * 2005-06-03 2014-04-14 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 단일 패러데이 전극에서의 전기발생 화학발광 및 전기화학
US20100261292A1 (en) 2009-04-10 2010-10-14 Meso Scale Technologies, Llc Methods for Conducting Assays
CN106018857B (zh) * 2009-07-27 2019-06-18 梅索磅秤技术有限公司 化验装置、耗材和方法
EP3644058A1 (de) 2010-10-14 2020-04-29 Meso Scale Technologies, LLC Reagenzienlagerung in einer assay-vorrichtung
SG189113A1 (en) 2010-10-25 2013-05-31 Hoffmann La Roche Use of signal enhancing compounds in electrochemiluminescence detection
EP2776833B1 (de) 2011-11-11 2018-09-05 Eli N. Glezer Cobinder-unterstützte testverfahren
CA2896541C (en) 2013-01-04 2020-04-21 Ian Chamberlin Assay apparatuses, methods and reagents
CA2904020C (en) 2013-03-11 2022-06-14 Meso Scale Technologies, Llc. Improved methods for conducting multiplexed assays
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
KR20230169418A (ko) 2013-03-13 2023-12-15 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
MX347461B (es) 2013-03-15 2017-04-26 Lubrizol Advanced Mat Inc Composiciones de cpvc libres de metales pesados.
CA2947747C (en) 2014-05-09 2024-03-05 Meso Scale Technologies, Llc. Graphene-modified electrodes
CA2948547A1 (en) 2014-05-15 2015-11-19 Meso Scale Technologies, Llc. Assay methods and kits for detecting an analyte of interest
WO2016091755A1 (en) 2014-12-08 2016-06-16 F. Hoffmann-La Roche Ag Method for measurement of vitamin d
CN108698047B (zh) 2016-03-11 2022-04-01 豪夫迈·罗氏有限公司 电化学发光检测中的支链胺
CN106124753B (zh) * 2016-07-08 2018-03-06 广州东林生物科技有限公司 电化学发光缓冲液及清洗液
US11686013B2 (en) 2018-02-23 2023-06-27 Meso Scale Technologies, Llc. Methods of screening antigen-binding molecules by normalizing for the concentration of antigen-binding molecule
US20210389304A1 (en) 2018-05-17 2021-12-16 Meso Scale Technologies, Llc. Methods for isolating surface marker displaying agents
EP3870348A1 (de) 2018-10-23 2021-09-01 Meso Scale Technologies, LLC Verfahren zur isolierung von oberflächenmarkerindikatoren
US20220018846A1 (en) 2019-01-03 2022-01-20 Meso Scale Technologies, Llc. Compositions and methods for carrying out assay measurements
KR20220010471A (ko) 2019-03-01 2022-01-25 메소 스케일 테크놀러지즈, 엘엘시 면역검정 방법에서 사용을 위한 전기화학발광성 표지화된 프로브, 이의 사용 방법 및 이를 포함하는 키트
JP2022535580A (ja) 2019-06-07 2022-08-09 エフ.ホフマン-ラ ロシュ アーゲー 全lnaオリゴヌクレオチドのハイブリダイズ
WO2021236584A1 (en) 2020-05-19 2021-11-25 Meso Scale Technologies, Llc. Methods, compositions, and kits for nucleic acid detection
AU2021299536A1 (en) 2020-07-01 2023-02-16 Meso Scale Technologies, Llc. Compositions and methods for assay measurements
JP2023539360A (ja) 2020-09-02 2023-09-13 メソ スケール テクノロジーズ エルエルシー サンプル中の1つ以上の標的分析物を検出するためのキット並びにそれを作製及び使用する方法
US20230349920A1 (en) 2020-09-04 2023-11-02 Meso Scale Technologies, Llc. Methods for isolating central nervous system surface marker displaying agents
JP2023554517A (ja) 2020-12-22 2023-12-27 エフ. ホフマン-ラ ロシュ アーゲー 試料中の目的の分析物を検出するための方法
WO2022187138A1 (en) 2021-03-01 2022-09-09 Meso Scale Technologies, Llc. System and method for conducting a multiplexed assay
EP4330672A1 (de) 2021-04-26 2024-03-06 Meso Scale Technologies, LLC. Verfahren zur isolierung und analyse eines zielanalyts, das von einem oberflächenmarker-anzeigemittel eingekapselt ist
WO2023129884A1 (en) 2021-12-30 2023-07-06 Meso Scale Technologies, Llc. Methods for electrochemiluminescence detection
WO2023156510A1 (en) 2022-02-18 2023-08-24 F. Hoffmann-La Roche Ag Method for detecting an analyte of interest in a sample
WO2023212315A2 (en) 2022-04-29 2023-11-02 Meso Scale Technologies, Llc. Methods for detecting and isolating extracellular vesicles

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AU9094982A (en) * 1982-02-01 1983-08-11 Miles Laboratories Inc. Photogenic labels to alleviate quenching in immuno assays
JPH0678985B2 (ja) * 1987-03-06 1994-10-05 ティーディーケイ株式会社 電気化学的光学特性検出用電極および電気化学的光学特性検出方法
DE68928994T2 (de) * 1988-11-03 1999-12-16 Igen Int Inc Elektrochemilumineszente testverfahren
JPH03107746A (ja) * 1989-09-21 1991-05-08 Tdk Corp 電気化学発光検出用容器

Also Published As

Publication number Publication date
JPH0534345A (ja) 1993-02-09
EP0500305A2 (de) 1992-08-26
EP0500305A3 (en) 1992-12-02
EP0500305B1 (de) 1996-12-18
US5240863A (en) 1993-08-31
DE69215925D1 (de) 1997-01-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8320 Willingness to grant licences declared (paragraph 23)
8339 Ceased/non-payment of the annual fee