DE69217497T2 - Verfahren zur synthese der verschiedenen sammlungen von oligomeren - Google Patents

Verfahren zur synthese der verschiedenen sammlungen von oligomeren

Info

Publication number
DE69217497T2
DE69217497T2 DE69217497T DE69217497T DE69217497T2 DE 69217497 T2 DE69217497 T2 DE 69217497T2 DE 69217497 T DE69217497 T DE 69217497T DE 69217497 T DE69217497 T DE 69217497T DE 69217497 T2 DE69217497 T2 DE 69217497T2
Authority
DE
Germany
Prior art keywords
synthesising
oligomers
component
different collections
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69217497T
Other languages
English (en)
Other versions
DE69217497D1 (de
Inventor
William Dower
Ronald Barrett
Mark Gallop
Michael Needels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymax Technologies NV
Original Assignee
Affymax Technologies NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25065309&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69217497(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Affymax Technologies NV filed Critical Affymax Technologies NV
Application granted granted Critical
Publication of DE69217497D1 publication Critical patent/DE69217497D1/de
Publication of DE69217497T2 publication Critical patent/DE69217497T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00277—Apparatus
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    • B01J2219/00306—Reactor vessels in a multiple arrangement
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    • B01J2219/00279—Features relating to reactor vessels
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00536—Sheets in the shape of disks
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    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00545—Colours
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00547—Bar codes
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
DE69217497T 1991-09-18 1992-09-16 Verfahren zur synthese der verschiedenen sammlungen von oligomeren Expired - Fee Related DE69217497T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76252291A 1991-09-18 1991-09-18
PCT/US1992/007815 WO1993006121A1 (en) 1991-09-18 1992-09-16 Method of synthesizing diverse collections of oligomers

Publications (2)

Publication Number Publication Date
DE69217497D1 DE69217497D1 (de) 1997-03-27
DE69217497T2 true DE69217497T2 (de) 1997-06-12

Family

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DE69217497T Expired - Fee Related DE69217497T2 (de) 1991-09-18 1992-09-16 Verfahren zur synthese der verschiedenen sammlungen von oligomeren

Country Status (11)

Country Link
US (7) US5770358A (de)
EP (2) EP0773227A1 (de)
JP (1) JP2001524926A (de)
AT (1) ATE148889T1 (de)
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US6143497A (en) 2000-11-07
US5770358A (en) 1998-06-23
GR3023156T3 (en) 1997-07-30
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CA2118806A1 (en) 1993-04-01
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JP2001524926A (ja) 2001-12-04
EP0773227A1 (de) 1997-05-14
EP0604552A1 (de) 1994-07-06
DE69217497D1 (de) 1997-03-27
US6416949B1 (en) 2002-07-09
ATE148889T1 (de) 1997-02-15
US6140493A (en) 2000-10-31
AU669489B2 (en) 1996-06-13
US5789162A (en) 1998-08-04
US6165717A (en) 2000-12-26
US5708153A (en) 1998-01-13
ES2097925T3 (es) 1997-04-16
AU2661992A (en) 1993-04-27
DK0604552T3 (da) 1997-08-04

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