DE69218265T2 - Apparat zur einbringung von medikamenten in rote blutkörperchen - Google Patents

Apparat zur einbringung von medikamenten in rote blutkörperchen

Info

Publication number
DE69218265T2
DE69218265T2 DE69218265T DE69218265T DE69218265T2 DE 69218265 T2 DE69218265 T2 DE 69218265T2 DE 69218265 T DE69218265 T DE 69218265T DE 69218265 T DE69218265 T DE 69218265T DE 69218265 T2 DE69218265 T2 DE 69218265T2
Authority
DE
Germany
Prior art keywords
suspension
unit
resealing
pct
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69218265T
Other languages
English (en)
Other versions
DE69218265D1 (de
Inventor
Etienne Pages
Claude Ropars
Christophe Bailleul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EUROP COMMUNITIES
Original Assignee
EUROP COMMUNITIES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EUROP COMMUNITIES filed Critical EUROP COMMUNITIES
Application granted granted Critical
Publication of DE69218265D1 publication Critical patent/DE69218265D1/de
Publication of DE69218265T2 publication Critical patent/DE69218265T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3692—Washing or rinsing blood or blood constituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/369—Temperature treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0429—Red blood cells; Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/366—General characteristics of the apparatus related to heating or cooling by liquid heat exchangers
DE69218265T 1991-07-03 1992-07-02 Apparat zur einbringung von medikamenten in rote blutkörperchen Expired - Fee Related DE69218265T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9108302A FR2678512B1 (fr) 1991-07-03 1991-07-03 Machine a internaliser.
PCT/FR1992/000623 WO1993000940A1 (fr) 1991-07-03 1992-07-02 Appareil pour faire penetrer des medicaments dans des globules rouges

Publications (2)

Publication Number Publication Date
DE69218265D1 DE69218265D1 (de) 1997-04-17
DE69218265T2 true DE69218265T2 (de) 1997-08-14

Family

ID=9414655

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69218265T Expired - Fee Related DE69218265T2 (de) 1991-07-03 1992-07-02 Apparat zur einbringung von medikamenten in rote blutkörperchen

Country Status (13)

Country Link
US (1) US5589389A (de)
EP (1) EP0679101B1 (de)
JP (1) JP3148239B2 (de)
AT (1) ATE149846T1 (de)
CA (1) CA2112685A1 (de)
DE (1) DE69218265T2 (de)
DK (1) DK0679101T3 (de)
ES (1) ES2098519T3 (de)
FI (1) FI935940A (de)
FR (1) FR2678512B1 (de)
GR (1) GR3023360T3 (de)
NO (1) NO306327B1 (de)
WO (1) WO1993000940A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0882448B1 (de) * 1997-05-05 2005-01-12 DIDECO S.r.l. Verfahren zur Verkapselung von biologisch aktiven Stoffen in Erythrocyten und Gerät dafür
AU2003260370B2 (en) 2002-08-05 2008-05-22 Silence Therapeutics Gmbh Further novel forms of interfering RNA molecules
FR2873925B1 (fr) * 2004-08-05 2006-10-13 Erytech Pharma Soc Par Actions Procede et dispositif de lyse-rescellement pour l'incorporation de principe actif notamment asparaginase ou inositol hexaphosphate, dans des erythrocytes
FR2884717B1 (fr) * 2005-04-25 2009-07-03 Erytech Pharma Soc Par Actions Erythrocytes renfermant de l'arginine deiminase
FR2919804B1 (fr) 2007-08-08 2010-08-27 Erytech Pharma Composition et vaccin therapeutique anti-tumoral
EP2242507B1 (de) * 2008-02-13 2013-02-20 Erytech Pharma Formulierung und verfahren zur vorbeugung und behandlung der skelettmanifestation von morbus gaucher
FR2928270B1 (fr) * 2008-03-10 2011-01-21 Erytech Pharma Formulation methode pour la prevention ou le traitement des metastases osseuses et autres maladies de l'os
FR2940087B1 (fr) 2008-12-18 2011-05-06 Lab Francais Du Fractionnement Erythrocytes contenant du facteur viii, preparation et utilisations.
IT1399590B1 (it) * 2010-04-26 2013-04-26 Erydel Spa Apparato e kit per incapsulare almeno un composto ad uso terapeutico e/o diagnostico all'interno di eritrociti
CN104394884A (zh) 2012-03-21 2015-03-04 爱瑞泰克药物公司 用于治疗急性髓细胞白血病(aml)的药剂
FR3005420B1 (fr) 2013-05-07 2015-09-18 Erytech Pharma Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues.
EP2813234A1 (de) 2013-06-11 2014-12-17 Erytech Pharma Zusammensetzung basierend auf Erythrocyten, in die Phenylalanin-Hydroxylase verkapselt ist, und therapeutische Verwendungen davon
EP3344575B1 (de) 2015-09-04 2020-04-15 SQZ Biotechnologies Company Intrazelluläres einbringen von biomolekülen in zellen mit einer zellwand
IT202100023375A1 (it) * 2021-09-09 2023-03-09 Yang Shunfa Dispositivo per la produzione di vescicole bioingegnerizzate dedicate e metodo correlato

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1501134B2 (de) * 1966-02-02 1976-08-12 Siemens AG, 1000 Berlin und 8000 München Vorrichtung zur veraenderung der temperatur von blut
US3839204A (en) * 1972-04-27 1974-10-01 Gen Electric Integral blood heat and component exchange device and two flow path membrane blood gas exchanger
US3853479A (en) * 1972-06-23 1974-12-10 Sherwood Medical Ind Inc Blood oxygenating device with heat exchanger
US4517080A (en) * 1980-06-18 1985-05-14 The United States Of America As Represented By The Secretary Of Agriculture Apparatus for encapsulating additives in resealed erythrocytes
US4327710A (en) * 1980-06-18 1982-05-04 The United States Of America As Represented By The Secretary Of Agriculture Process for encapsulating additives in resealed erythrocytes for disseminating chemicals via the circulatory system
FR2529463B1 (fr) * 1982-07-05 1986-01-10 Centre Nat Rech Scient Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus
US4668214A (en) * 1986-06-09 1987-05-26 Electromedics, Inc. Method of washing red blood cells
NL8701233A (nl) * 1987-05-22 1988-12-16 Medistad Holland Bloedverwarmingstoestel.

Also Published As

Publication number Publication date
ATE149846T1 (de) 1997-03-15
GR3023360T3 (en) 1997-08-29
FI935940A0 (fi) 1993-12-30
NO306327B1 (no) 1999-10-25
NO934899D0 (no) 1993-12-29
NO934899L (no) 1994-03-01
JP3148239B2 (ja) 2001-03-19
CA2112685A1 (fr) 1993-01-21
ES2098519T3 (es) 1997-05-01
JPH06509250A (ja) 1994-10-20
EP0679101A1 (de) 1995-11-02
WO1993000940A1 (fr) 1993-01-21
DE69218265D1 (de) 1997-04-17
FI935940A (fi) 1994-02-17
DK0679101T3 (da) 1997-09-22
US5589389A (en) 1996-12-31
EP0679101B1 (de) 1997-03-12
FR2678512A1 (fr) 1993-01-08
FR2678512B1 (fr) 1995-06-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee