DE69229681D1 - Ein protein, das spezifische dna-strukturen erkennt, und seine verwendungen - Google Patents
Ein protein, das spezifische dna-strukturen erkennt, und seine verwendungenInfo
- Publication number
- DE69229681D1 DE69229681D1 DE69229681T DE69229681T DE69229681D1 DE 69229681 D1 DE69229681 D1 DE 69229681D1 DE 69229681 T DE69229681 T DE 69229681T DE 69229681 T DE69229681 T DE 69229681T DE 69229681 D1 DE69229681 D1 DE 69229681D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- dna
- specific dna
- recognition protein
- specific recognition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
- C07K14/43581—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies from Drosophila
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/142—Toxicological screening, e.g. expression profiles which identify toxicity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/814,964 US5359047A (en) | 1988-09-22 | 1991-12-26 | Nucleic acids encoding DNA structure-specific recognition protein and uses therefor |
PCT/US1992/011107 WO1993013222A1 (en) | 1991-12-26 | 1992-12-18 | Dna structure-specific recognition protein and uses therefor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69229681D1 true DE69229681D1 (de) | 1999-09-02 |
DE69229681T2 DE69229681T2 (de) | 2000-04-06 |
Family
ID=25216483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69229681T Expired - Fee Related DE69229681T2 (de) | 1991-12-26 | 1992-12-18 | Ein protein, das spezifische dna-strukturen erkennt, und seine verwendungen |
Country Status (7)
Country | Link |
---|---|
US (2) | US5359047A (de) |
EP (1) | EP0621902B1 (de) |
JP (1) | JPH07502415A (de) |
AT (1) | ATE182628T1 (de) |
CA (1) | CA2125673C (de) |
DE (1) | DE69229681T2 (de) |
WO (1) | WO1993013222A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5705334A (en) * | 1988-09-22 | 1998-01-06 | Massachusetts Institute Of Technology | Uses for DNA structure-specific recognition protein |
US5874218A (en) * | 1990-06-11 | 1999-02-23 | Nexstar Pharmaceuticals, Inc. | Method for detecting a target compound in a substance using a nucleic acid ligand |
US5874283A (en) * | 1995-05-30 | 1999-02-23 | John Joseph Harrington | Mammalian flap-specific endonuclease |
US5912332A (en) * | 1996-07-26 | 1999-06-15 | Hybridon, Inc. | Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides |
US6030783A (en) * | 1997-01-31 | 2000-02-29 | Massachusetts Institute Of Technology | Photo-potentiation of cisplatin chemotherapy |
AU4839999A (en) | 1998-06-29 | 2000-01-17 | Myriad Genetics, Inc. | Tmprss2 is a tumor suppressor |
US8114850B2 (en) | 1999-04-08 | 2012-02-14 | Advanced Cancer Therapeutics, Llc | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
AU775412B2 (en) | 1999-04-08 | 2004-07-29 | Advanced Cancer Therapeutics, Inc. | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
US20080318890A1 (en) * | 1999-04-08 | 2008-12-25 | Antisoma Research Limited | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
US7960540B2 (en) | 1999-04-08 | 2011-06-14 | Advanced Cancer Therapeutics, Llc | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
US20080318889A1 (en) * | 1999-04-08 | 2008-12-25 | Antisoma Research Limited | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
CA2385528C (en) | 1999-10-01 | 2013-12-10 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
US6573050B1 (en) | 1999-10-29 | 2003-06-03 | Sunnybrook & Women's College Health Sciences Centre | Treatment, diagnosis and evaluation of anti-cancer therapy resistance in melanoma |
FR2809417B1 (fr) * | 2000-05-24 | 2004-07-30 | Commissariat Energie Atomique | Detection et caracterisation de l'activite de proteines impliquees dans la reparation de lesions de l'adn |
DE10030452A1 (de) * | 2000-06-21 | 2002-01-24 | Max Planck Gesellschaft | Assay zur Detektion von primären DNA-Schäden |
US6806289B1 (en) | 2000-07-14 | 2004-10-19 | Stephen J. Lippard | Coordination complexes, and methods for preparing by combinatorial methods, assaying and using the same |
EP1412746A4 (de) * | 2001-07-12 | 2007-08-08 | Exelixis Inc | HADHs ALS MODIFIKATOREN DES P21-WEGS UND VERWENDUNGSVERFAHREN |
ITTO20010762A1 (it) * | 2001-07-31 | 2003-01-31 | Consiglio Nazionale Ricerche | Anticorpi monoclonali anti-ssrp-1 ed ibridomi producenti tali anticorpi. |
JP4007000B2 (ja) * | 2001-12-25 | 2007-11-14 | 富士ゼロックス株式会社 | 導電性有機高分子 |
WO2003064698A1 (en) * | 2002-01-25 | 2003-08-07 | Board Of Regents, The University Of Texas System | Electrophoretic assay to predict risk of cancer and the efficacy and toxicity of cancer therapy |
US7153691B2 (en) * | 2002-11-13 | 2006-12-26 | G6 Science Corp. | Method of identifying and assessing DNA euchromatin in biological cells for detecting disease, monitoring wellness, assessing bio-activity, and screening pharmacological agents |
WO2007126078A1 (ja) * | 2006-04-27 | 2007-11-08 | Onecell Inc. | ヌクレオチド-遷移金属錯体触媒 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4407942A (en) * | 1981-01-29 | 1983-10-04 | Atomic Energy Of Canada Limited | Fluorescent detection of DNA damage |
US4670388A (en) * | 1982-12-30 | 1987-06-02 | Carnegie Institution Of Washington | Method of incorporating DNA into genome of drosophila |
JPS6343931A (ja) * | 1986-08-12 | 1988-02-25 | Diafoil Co Ltd | 磁気記録媒体用ポリエステルフイルム |
EP0435957A1 (de) * | 1988-09-22 | 1991-07-10 | Massachusetts Institute Of Technology | Dna-schadenbindender faktor und seine verwendung |
-
1991
- 1991-12-26 US US07/814,964 patent/US5359047A/en not_active Expired - Fee Related
-
1992
- 1992-12-18 JP JP5511838A patent/JPH07502415A/ja not_active Ceased
- 1992-12-18 EP EP93901926A patent/EP0621902B1/de not_active Expired - Lifetime
- 1992-12-18 CA CA002125673A patent/CA2125673C/en not_active Expired - Fee Related
- 1992-12-18 AT AT93901926T patent/ATE182628T1/de not_active IP Right Cessation
- 1992-12-18 WO PCT/US1992/011107 patent/WO1993013222A1/en active IP Right Grant
- 1992-12-18 DE DE69229681T patent/DE69229681T2/de not_active Expired - Fee Related
-
1994
- 1994-06-09 US US08/258,442 patent/US5670621A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5359047A (en) | 1994-10-25 |
DE69229681T2 (de) | 2000-04-06 |
CA2125673C (en) | 2001-03-13 |
EP0621902B1 (de) | 1999-07-28 |
ATE182628T1 (de) | 1999-08-15 |
JPH07502415A (ja) | 1995-03-16 |
EP0621902A1 (de) | 1994-11-02 |
US5670621A (en) | 1997-09-23 |
WO1993013222A1 (en) | 1993-07-08 |
CA2125673A1 (en) | 1993-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |