DE69231486T2 - Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung - Google Patents

Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung

Info

Publication number
DE69231486T2
DE69231486T2 DE69231486T DE69231486T DE69231486T2 DE 69231486 T2 DE69231486 T2 DE 69231486T2 DE 69231486 T DE69231486 T DE 69231486T DE 69231486 T DE69231486 T DE 69231486T DE 69231486 T2 DE69231486 T2 DE 69231486T2
Authority
DE
Germany
Prior art keywords
regeneration
dexamethasone
composition containing
tissue repair
pdgf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69231486T
Other languages
English (en)
Other versions
DE69231486D1 (de
Inventor
Robert Bruce Rutherford
Marc F Charette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Connecticut
Creative Biomolecules Inc
Original Assignee
University of Connecticut
Creative Biomolecules Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Connecticut, Creative Biomolecules Inc filed Critical University of Connecticut
Publication of DE69231486D1 publication Critical patent/DE69231486D1/de
Application granted granted Critical
Publication of DE69231486T2 publication Critical patent/DE69231486T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69231486T 1991-03-12 1992-03-12 Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung Expired - Fee Related DE69231486T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/669,070 US5149691A (en) 1991-03-12 1991-03-12 Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
PCT/US1992/002043 WO1992016181A2 (en) 1991-03-12 1992-03-12 Composition for promoting tissue repair and regeneration

Publications (2)

Publication Number Publication Date
DE69231486D1 DE69231486D1 (de) 2000-11-02
DE69231486T2 true DE69231486T2 (de) 2001-04-26

Family

ID=24684879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69231486T Expired - Fee Related DE69231486T2 (de) 1991-03-12 1992-03-12 Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung

Country Status (8)

Country Link
US (2) US5149691A (de)
EP (1) EP0575484B1 (de)
JP (1) JPH07505858A (de)
AT (1) ATE196604T1 (de)
AU (1) AU656372B2 (de)
CA (1) CA2106073C (de)
DE (1) DE69231486T2 (de)
WO (1) WO1992016181A2 (de)

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US5770209A (en) * 1991-08-30 1998-06-23 University Of South Florida Acceleration of wound healing using connective tissue growth factor
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US5408040A (en) * 1991-08-30 1995-04-18 University Of South Florida Connective tissue growth factor(CTGF)
US5837258A (en) 1991-08-30 1998-11-17 University Of South Florida Induction of tissue, bone or cartilage formation using connective tissue growth factor
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US20060076295A1 (en) 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
ATE510605T1 (de) 2003-03-14 2011-06-15 Univ Columbia Systeme und verfahren für auf blut basierende therapien mit einer membranlosen mikrofluid- austauschvorrichtung
US7309232B2 (en) * 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
US7258875B2 (en) * 2003-12-04 2007-08-21 Chiou Consulting, Inc. Compositions and methods for topical treatment of skin infection
US8293890B2 (en) * 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
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US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US20060115266A1 (en) * 2004-12-01 2006-06-01 Gil Levi All-optical protection signaling systems and methods in optical communication networks
US8119591B2 (en) * 2005-08-01 2012-02-21 Genera Istrazivanja D.O.O. Methods and compositions for regenerating articular cartilage
WO2007061889A2 (en) 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
CA2640064A1 (en) 2006-01-23 2007-07-26 Imagene Co., Ltd. Novel peptide and use thereof
CA2641860C (en) * 2006-02-09 2015-07-14 Biomimetic Therapeutics, Inc. Compositions and methods for treating bone
ATE542583T1 (de) 2006-05-22 2012-02-15 Univ Columbia Verfahren für membranlosen mikrofluidaustausch in einem h-filter und filterung der extraktionsflüssigkeitsausgangsströme
JP5484047B2 (ja) 2006-06-30 2014-05-07 バイオミメティック セラピューティクス， エルエルシー 回旋筋腱板傷害を処置するためのｐｄｇｆ−生体マトリックス組成物および方法
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
US8106008B2 (en) 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
AU2013203287B2 (en) * 2006-11-03 2015-12-17 Biomimetic Therapeutics, Llc. Compositions and methods for arthrodetic procedures
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WO2009052221A2 (en) * 2007-10-15 2009-04-23 The Regents Of The University Of Colorado Methods for extracting platelets and compositions obtained therefrom
EP2244724B1 (de) 2008-01-07 2015-04-01 Rapid Pathogen Screening, Inc. Verwendung von peptiden zur förderung der wundheilung
JP2011514182A (ja) 2008-02-04 2011-05-06 ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク 流体分離装置、システム、及び方法
CN102014977B (zh) 2008-02-07 2015-09-02 生物模拟治疗有限责任公司 用于牵引成骨术的组合物和方法
AU2009291828C1 (en) 2008-09-09 2016-03-17 Biomimetic Therapeutics, Llc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
US20120100111A1 (en) * 2009-03-06 2012-04-26 Universite Paris Descartes Method for treating cancer
JP6144049B2 (ja) 2010-02-22 2017-06-07 バイオミメティック セラピューティクス，リミテッド ライアビリティ カンパニー 腱障害を処置するための血小板由来成長因子組成物及び方法
CA2802471A1 (en) 2010-06-14 2011-12-22 Gene Signal International Sa Novel peptides for wound healing
EP2395015B1 (de) 2010-06-14 2013-03-06 Gene Signal International SA Peptide für die Wundheilung
US8288334B2 (en) 2010-06-14 2012-10-16 Gene Signal International Sa Peptides for wound healing
US20130202576A1 (en) 2010-07-12 2013-08-08 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
WO2013062995A1 (en) * 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating deep partial and full thickness wounds and injuries
RU2659423C2 (ru) 2012-02-16 2018-07-02 ЭйТИР ФАРМА, ИНК. ГИСТИДИЛ-тРНК-СИНТЕТАЗЫ ДЛЯ ЛЕЧЕНИЯ АУТОИММУННЫХ И ВОСПАЛИТЕЛЬНЫХ ЗАБОЛЕВАНИЙ
DK3460054T3 (da) 2013-03-15 2021-01-18 Atyr Pharma Inc Histidyl-tRNA-syntetase-Fc-konjugater
CA2962954A1 (en) 2014-10-14 2016-04-21 Samuel Lynch Compositions for treating wounds
JP2020517638A (ja) 2017-04-20 2020-06-18 エータイアー ファーマ， インコーポレイテッド 肺の炎症を治療するための組成物および方法
KR20200060997A (ko) 2018-11-23 2020-06-02 (주)메디코스바이오텍 창상치료용 약학조성물
CZ308845B6 (cs) 2019-01-21 2021-07-07 Globetech Innovation S.R.O Farmaceutická směs topicky hojivých peptidových složek pro použití k topické léčbě kožních defektů a/nebo k topickému hojení ran
PL433169A1 (pl) 2020-03-06 2021-09-13 Gdański Uniwersytet Medyczny Lipopeptydowe koniugaty i ich sole, sposób wytwarzania lipopeptydowych koniugatów i ich soli, kompozycja farmaceutyczna zawierająca lipopeptydowy koniugat i jego sole do leczenia ran przewlekłych

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ATE169226T1 (de) * 1991-04-12 1998-08-15 Creative Biomolecules Inc Verwendung von aus blutplättchen gewonnenem wachstumsfaktor zur herstellung eines medikaments zur behandlung von gastrointestinaler geschwüre

Also Published As

Publication number Publication date
AU656372B2 (en) 1995-02-02
EP0575484B1 (de) 2000-09-27
DE69231486D1 (de) 2000-11-02
US5149691A (en) 1992-09-22
WO1992016181A2 (en) 1992-10-01
JPH07505858A (ja) 1995-06-29
AU1559192A (en) 1992-10-21
CA2106073A1 (en) 1993-09-13
CA2106073C (en) 2003-09-30
EP0575484A1 (de) 1993-12-29
WO1992016181A3 (en) 1992-11-12
ATE196604T1 (de) 2000-10-15
US5376636A (en) 1994-12-27

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee