DE69232716T2 - Peptide mit thrombospondin-ähnlicher Aktivität und ihre therapeutische Verwendung - Google Patents
Peptide mit thrombospondin-ähnlicher Aktivität und ihre therapeutische VerwendungInfo
- Publication number
- DE69232716T2 DE69232716T2 DE69232716T DE69232716T DE69232716T2 DE 69232716 T2 DE69232716 T2 DE 69232716T2 DE 69232716 T DE69232716 T DE 69232716T DE 69232716 T DE69232716 T DE 69232716T DE 69232716 T2 DE69232716 T2 DE 69232716T2
- Authority
- DE
- Germany
- Prior art keywords
- thrombospondin
- peptides
- activity
- therapeutic use
- therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70525591A | 1991-05-22 | 1991-05-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69232716D1 DE69232716D1 (de) | 2002-09-12 |
DE69232716T2 true DE69232716T2 (de) | 2002-11-28 |
Family
ID=24832676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69232716T Expired - Fee Related DE69232716T2 (de) | 1991-05-22 | 1992-05-08 | Peptide mit thrombospondin-ähnlicher Aktivität und ihre therapeutische Verwendung |
Country Status (7)
Country | Link |
---|---|
US (1) | US5654277A (de) |
EP (1) | EP0514721B1 (de) |
JP (2) | JP3706151B2 (de) |
AU (1) | AU1636492A (de) |
CA (1) | CA2063055A1 (de) |
DE (1) | DE69232716T2 (de) |
ES (1) | ES2181670T3 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5610148A (en) * | 1991-01-18 | 1997-03-11 | University College London | Macroscopically oriented cell adhesion protein for wound treatment |
US5629287A (en) * | 1991-01-18 | 1997-05-13 | University College London | Depot formulations |
DE4203545A1 (de) * | 1992-02-07 | 1993-08-12 | Behringwerke Ag | Spezifische antikoerper gegen aktivierte plaettchen, ihre herstellung und ihre verwendung in diagnose und therapie |
AU5161296A (en) * | 1995-04-21 | 1996-11-07 | Allelix Biopharmaceuticals Inc. | Anti-haemorrhagic peptides |
AU5699996A (en) * | 1995-06-02 | 1996-12-18 | Allelix Biopharmaceuticals Inc. | Anti-inflammatory thrombospondin-derived peptides |
ATE307584T1 (de) * | 1997-08-28 | 2005-11-15 | Nissan Chemical Ind Ltd | Mittel zur förderung und verstärkung der neovaskularisierung |
WO1999061466A1 (en) * | 1998-05-22 | 1999-12-02 | Abbott Laboratories | Antiangiogenic drug to treat cancer, arthritis and retinopathy |
US6716963B1 (en) | 1998-05-22 | 2004-04-06 | Abbott Laboratories | Peptide antiangiogenic drugs |
US6380161B1 (en) | 1999-06-21 | 2002-04-30 | Inkine Pharmaceutical Company, Inc. | Compositions for treating chemotherapy-resistant tumor cells and targeted chemotherapy compositions |
CN1297930A (zh) * | 1999-11-29 | 2001-06-06 | 上海博容基因开发有限公司 | 一种新的多肽——人凝血栓蛋白30和编码这种多肽的多核苷酸 |
US7740841B1 (en) * | 2000-01-28 | 2010-06-22 | Sunnybrook Health Science Center | Therapeutic method for reducing angiogenesis |
US7655411B2 (en) * | 2002-08-23 | 2010-02-02 | W2 Holdings, Inc. | Thrombospondin fragments and binding agents in the detection, diagnosis and evaluation of cancer |
EP2776055B1 (de) * | 2011-08-17 | 2016-12-14 | Ironwood Pharmaceuticals, Inc. | Behandlungen für magen-darm-erkrankungen |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8819209D0 (en) * | 1988-08-12 | 1988-09-14 | Research Corp Ltd | Polypeptide & dna encoding same |
US5192744A (en) * | 1990-01-12 | 1993-03-09 | Northwestern University | Method of inhibiting angiogenesis of tumors |
US5190918A (en) * | 1990-02-22 | 1993-03-02 | W. R. Grace & Co.-Conn. | Peptide fragments and analogs of thrombospondin and methods of use |
US5200397A (en) * | 1990-02-22 | 1993-04-06 | W. R. Grace & Co.-Conn. | Use of peptide analogs of thrombospondin for the inhibition of angiogenic activity |
DE69132708T2 (de) * | 1990-09-24 | 2002-06-20 | Grace W R & Co | Therapeutische Vervendung von Peptiden mit Thrombospondin - ähnlicher Aktivität |
-
1992
- 1992-03-13 CA CA002063055A patent/CA2063055A1/en not_active Abandoned
- 1992-05-08 EP EP92107774A patent/EP0514721B1/de not_active Expired - Lifetime
- 1992-05-08 ES ES92107774T patent/ES2181670T3/es not_active Expired - Lifetime
- 1992-05-08 DE DE69232716T patent/DE69232716T2/de not_active Expired - Fee Related
- 1992-05-18 AU AU16364/92A patent/AU1636492A/en not_active Abandoned
- 1992-05-20 JP JP15119092A patent/JP3706151B2/ja not_active Expired - Fee Related
-
1995
- 1995-06-01 US US08/458,998 patent/US5654277A/en not_active Expired - Lifetime
-
2005
- 2005-06-08 JP JP2005168928A patent/JP2005272480A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2005272480A (ja) | 2005-10-06 |
JP3706151B2 (ja) | 2005-10-12 |
EP0514721A1 (de) | 1992-11-25 |
DE69232716D1 (de) | 2002-09-12 |
AU1636492A (en) | 1992-11-26 |
US5654277A (en) | 1997-08-05 |
ES2181670T3 (es) | 2003-03-01 |
EP0514721B1 (de) | 2002-08-07 |
JPH05178757A (ja) | 1993-07-20 |
CA2063055A1 (en) | 1992-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |