DE69315483D1 - Vernetzbare Kollagenderivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Biomaterialien - Google Patents

Vernetzbare Kollagenderivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Biomaterialien

Info

Publication number
DE69315483D1
DE69315483D1 DE69315483T DE69315483T DE69315483D1 DE 69315483 D1 DE69315483 D1 DE 69315483D1 DE 69315483 T DE69315483 T DE 69315483T DE 69315483 T DE69315483 T DE 69315483T DE 69315483 D1 DE69315483 D1 DE 69315483D1
Authority
DE
Germany
Prior art keywords
biomaterials
processes
collagen
preparation
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69315483T
Other languages
English (en)
Other versions
DE69315483T2 (de
Inventor
Christian Gagnieu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamel Technologies SA
Original Assignee
Flamel Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flamel Technologies SA filed Critical Flamel Technologies SA
Publication of DE69315483D1 publication Critical patent/DE69315483D1/de
Application granted granted Critical
Publication of DE69315483T2 publication Critical patent/DE69315483T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/102—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
DE69315483T 1992-06-18 1993-06-17 Vernetzbare Kollagenderivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Biomaterialien Expired - Fee Related DE69315483T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9207692A FR2692582B1 (fr) 1992-06-18 1992-06-18 Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.

Publications (2)

Publication Number Publication Date
DE69315483D1 true DE69315483D1 (de) 1998-01-15
DE69315483T2 DE69315483T2 (de) 1998-07-02

Family

ID=9431095

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69315483T Expired - Fee Related DE69315483T2 (de) 1992-06-18 1993-06-17 Vernetzbare Kollagenderivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Biomaterialien

Country Status (7)

Country Link
US (1) US5412076A (de)
EP (1) EP0575273B1 (de)
JP (1) JPH0680935A (de)
AT (1) ATE160798T1 (de)
DE (1) DE69315483T2 (de)
ES (1) ES2113511T3 (de)
FR (1) FR2692582B1 (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936035A (en) * 1988-11-21 1999-08-10 Cohesion Technologies, Inc. Biocompatible adhesive compositions
US5614587A (en) * 1988-11-21 1997-03-25 Collagen Corporation Collagen-based bioadhesive compositions
US5219895A (en) * 1991-01-29 1993-06-15 Autogenesis Technologies, Inc. Collagen-based adhesives and sealants and methods of preparation and use thereof
FR2699184B1 (fr) * 1992-12-16 1995-03-10 Flamel Tech Sa Nouveaux dérivés de collagène, leur procédé d'obtention et leur application à la préparation de biomatériaux.
FR2715309B1 (fr) * 1994-01-24 1996-08-02 Imedex Composition adhésive, à usage chirurgical, à base de collagène modifié par coupure oxydative et non réticulé.
ATE244584T1 (de) * 1995-01-16 2003-07-15 Baxter Int Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
DE19530249A1 (de) * 1995-08-17 1997-02-20 Resorba Chirurgisches Nahtmate Brustimplantat
US6833408B2 (en) 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
US6458889B1 (en) 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
PT876165E (pt) 1995-12-18 2006-10-31 Angiotech Biomaterials Corp Composicoes de polimeros reticulados e processos para a sua utilizacao
IT1285308B1 (it) * 1996-03-12 1998-06-03 Sorin Biomedica Cardio Spa Procedimento per la preparazione di materiale biologico per impianto
AU3720097A (en) 1996-07-12 1998-02-09 Baxter International Inc. A fibrin delivery device and method for forming fibrin on a surface
US5856308A (en) * 1996-09-27 1999-01-05 Haemacure Corporation Artificial collagen
JP3693491B2 (ja) * 1997-07-11 2005-09-07 株式会社カネカ 改良された再生コラーゲン繊維及びその製造方法
WO1999033419A1 (en) * 1997-12-31 1999-07-08 Depuy Orthopaedics, Inc. Tissue reactive adhesive compositions
US6251579B1 (en) * 1998-02-13 2001-06-26 Sulzer Carbomedics Inc. Oxidative stabilization of collagen containing materials
MXPA00010110A (es) * 1998-04-17 2002-08-06 Angiogenix Inc Factores angiogenicos terapeuticos y metodos para su uso.
BE1012536A3 (fr) 1998-11-04 2000-12-05 Baxter Int Element muni d'une couche de fibrine sa preparation et son utilisation.
AT406054B (de) 1998-11-04 2000-02-25 Andreas Bernkop-Schnuerch Verfahren zur verbesserung der mucoadhäsion von polymeren sowie deren herstellung und verwendung
US6326025B1 (en) * 1998-12-30 2001-12-04 Depuy Orthopaedics, Inc Tissue reactive adhesive compositions
FR2790391B1 (fr) * 1999-03-02 2002-11-15 Flamel Tech Sa Moyen pour la prevention des adherences post-chirurgicales,a base de peptides collagenique reticule
FR2790475B1 (fr) * 1999-03-02 2003-01-24 Flamel Tech Sa Peptides collageniques modifies par greffage de fonctions mercapto, l'un de leurs procedes d'obtention et leurs applications comme biomateriaux
FR2801313A1 (fr) * 1999-05-19 2001-05-25 Coletica Produit collagenique contenant du collagene d'origine marine a faible odeur et de preference a proprietes mecaniques ameliorees, ainsi que son utilisation sous forme de compositions ou de produits cosmetiques ou pharmaceutiques
US6183498B1 (en) 1999-09-20 2001-02-06 Devore Dale P. Methods and products for sealing a fluid leak in a tissue
US6463335B1 (en) 1999-10-04 2002-10-08 Medtronic, Inc. Temporary medical electrical lead having electrode mounting pad with biodegradable adhesive
DE19954036A1 (de) * 1999-10-29 2001-05-10 Siemens Ag Verfahren und Anordnung zur Wellenlängenstabilisierung von Licht
US20030035786A1 (en) * 1999-11-04 2003-02-20 Medtronic, Inc. Biological tissue adhesives, articles, and methods
US6479079B1 (en) 1999-12-13 2002-11-12 Sulzer Carbomedics Inc. Anticalcification treatments for fixed biomaterials
US6309454B1 (en) 2000-05-12 2001-10-30 Johnson & Johnson Medical Limited Freeze-dried composite materials and processes for the production thereof
FR2809412A1 (fr) 2000-05-26 2001-11-30 Coletica Utilisation de collagene d'origine aquatique pour la realisation de supports destines a l'ingenierie tissulaire, et supports et biomateriaux obtenus
US6790454B1 (en) 2000-05-26 2004-09-14 Coletica Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained
US6974679B2 (en) * 2000-05-26 2005-12-13 Coletica Support with collagen base for tissue engineering and manufacture of biomaterials
AU2004268628B2 (en) * 2001-08-31 2009-11-12 Spinal Simplicity, Llc Crosslinking reagents for treating intervertebral disc disorders
US8119599B2 (en) * 2001-08-31 2012-02-21 Orthopeutics, L.P. Direct application of non-toxic crosslinking reagents to resist progressive spinal degeneration and deformity
US7001988B2 (en) * 2001-09-25 2006-02-21 Keraplast Technologies, Ltd. Methods for controlling peptide solubility, chemically modified peptides, and stable solvent systems for producing same
US6939364B1 (en) 2001-10-09 2005-09-06 Tissue Adhesive Technologies, Inc. Composite tissue adhesive
US6773699B1 (en) * 2001-10-09 2004-08-10 Tissue Adhesive Technologies, Inc. Light energized tissue adhesive conformal patch
US6875427B1 (en) 2001-10-09 2005-04-05 Tissue Adhesive Technologies, Inc. Light energized tissue adhesive
US6780840B1 (en) 2001-10-09 2004-08-24 Tissue Adhesive Technologies, Inc. Method for making a light energized tissue adhesive
US7001987B2 (en) * 2002-04-22 2006-02-21 Keraplast Technologies, Ltd. Hydrogel with controllable mechanical, chemical, and biological properties and method for making same
US20040120910A1 (en) * 2002-04-10 2004-06-24 Dyke Mark Van Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks
JP2006508027A (ja) * 2002-04-10 2006-03-09 ケラプラスト テクノロジーズ， リミテッド シリコーン含有結合によって架橋された不均質タンパク質ネットワーク、およびそれらを生成する方法
US6914126B2 (en) * 2002-04-10 2005-07-05 Keraplast Technologies, Ltd. Methods for producing, films comprising, and methods for using heterogenous crosslinked protein networks
US6989437B2 (en) * 2002-04-10 2006-01-24 Keraplast Technologies, Ltd. Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks
US20040062793A1 (en) * 2002-07-05 2004-04-01 Dyke Mark Van Tissue defect dressings comprising proteinaceous networks
US7163321B2 (en) * 2002-07-25 2007-01-16 Steven Contarino Emergency vehicle grille
US7135027B2 (en) 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
US20050175659A1 (en) * 2004-02-09 2005-08-11 Macomber Laurel R. Collagen device and method of preparing the same
US20050283256A1 (en) * 2004-02-09 2005-12-22 Codman & Shurtleff, Inc. Collagen device and method of preparing the same
GB0403406D0 (en) * 2004-02-17 2004-03-24 Biotransys Ltd Preparation of carriers for drug delivery and other therapeutic applications
US20050244460A1 (en) * 2004-04-29 2005-11-03 Ivan Alferiev Biodegradable crosslinking strategies using triglycidyl amine (TGA)
WO2006034128A2 (en) 2004-09-17 2006-03-30 Angiotech Biomaterials Corporation Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
CA2518298A1 (fr) * 2005-09-06 2007-03-06 Chaimed Technologies Inc. Polymeres biodegradables, leur preparation et leur usage pour la fabrication de pansements
US7429241B2 (en) * 2005-09-29 2008-09-30 Codman & Shurtleff, Inc. Dural graft and method of preparing the same
US20070087059A1 (en) * 2005-10-17 2007-04-19 Frank Everaerts Bioactive delivery matrix compositions and methods
US8263405B2 (en) * 2005-11-24 2012-09-11 Mitsuru Akashi Controllably degradable hydrogel for culturing cells to produce three-dimensionally organized cells
CN101622007A (zh) 2006-10-06 2010-01-06 人类起源公司 天然(端肽)胎盘胶原组合物
DK2148691T3 (en) 2007-02-05 2015-08-17 Apellis Pharmaceuticals Inc Compstatinanaloger for use in the treatment of inflammatory states of the respiratory system
US10278947B2 (en) 2007-02-28 2019-05-07 Orthopeutics, L.P. Crosslinker enhanced repair of connective tissues
AU2009201541B2 (en) * 2008-04-23 2014-12-04 Integra Lifesciences Corporation Flowable collagen material for dural closure
KR101341732B1 (ko) 2010-01-28 2013-12-20 전남대학교산학협력단 난소암 진단을 위한 콜라겐 유형 ⅵ 알파 １의 신규한 용도
US9617298B2 (en) * 2010-07-30 2017-04-11 Nippi, Incorporated Collagen powder and/or collagen-derived powder, and production method for the same
RU2019101641A (ru) 2012-12-07 2019-03-20 Антродженезис Корпорейшн Лечение поражений полости рта при помощи внеклеточного матрикса плаценты
NO2975611T3 (de) 2013-03-15 2018-06-09
WO2014209856A1 (en) 2013-06-24 2014-12-31 Anthrogenesis Corporation Extracellular matrix composition beads for cell culture
FR3012978A1 (fr) 2013-11-12 2015-05-15 Biocarecell Filtre biocompatible et procede de fabrication d'un filtre biocompatible.
CN106456536B (zh) 2014-05-07 2020-05-12 克罗马药品股份有限公司 水性眼用溶液和治疗干眼综合征的方法
JP7099822B2 (ja) * 2014-08-28 2022-07-12 ミメディクス グループ インコーポレイテッド コラーゲンで強化した組織移植片
US10851152B2 (en) 2015-06-25 2020-12-01 Kola-Gen Pharma, Inc. Polymerized peptide and gel having collagen-like structure
WO2017015354A1 (en) * 2015-07-22 2017-01-26 Anexis, Llc Collagen based materials and methods of using them
PL3368007T3 (pl) 2015-10-30 2020-11-02 Croma-Pharma Gmbh Zastosowanie terapeutyczne sterylnego wodnego roztworu oftalmicznego
EP3368006B1 (de) 2015-10-30 2019-12-04 Croma-Pharma Gesellschaft m.b.H. Therapeutische verwendung einer sterilen wässrigen ophthalmischen lösung
CN108619559A (zh) * 2018-05-09 2018-10-09 浙江海洋大学 一种日本黄姑鱼鱼皮胶原蛋白医用海绵的制备方法
GB202005141D0 (en) * 2020-04-07 2020-05-20 Jellagen Pty Ltd Jellyfish collagen use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294241A (en) * 1977-06-09 1981-10-13 Teruo Miyata Collagen skin dressing
DE3037513C2 (de) * 1980-10-03 1983-05-05 Steffan, Wolfgang, 8425 Neustadt Kollagene Wundauflage
JPS61168363A (ja) * 1985-01-22 1986-07-30 株式会社　高研 ビスコサ−ジヤリ用及び代用硝子体用のスクシニル化アテロコラ−ゲン溶液
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
DE3937076A1 (de) * 1989-11-07 1991-05-08 Heyl Chem Pharm Kollagene, verfahren zu ihrer herstellung und kosmetische mittel
US5219895A (en) * 1991-01-29 1993-06-15 Autogenesis Technologies, Inc. Collagen-based adhesives and sealants and methods of preparation and use thereof

Also Published As

Publication number Publication date
FR2692582A1 (fr) 1993-12-24
EP0575273A1 (de) 1993-12-22
EP0575273B1 (de) 1997-12-03
ES2113511T3 (es) 1998-05-01
JPH0680935A (ja) 1994-03-22
DE69315483T2 (de) 1998-07-02
ATE160798T1 (de) 1997-12-15
US5412076A (en) 1995-05-02
FR2692582B1 (fr) 1998-09-18

Similar Documents

Publication Publication Date Title
DE69315483D1 (de) Vernetzbare Kollagenderivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Biomaterialien
DE68911178D1 (de) Klinische Entwicklungen mit Amnionzellen.
DE68907397T2 (de) Flüssige photopolymerisierbare Zusammensetzung, viskoelastisches Produkt, erhalten aus dieser Zusammensetzung und Verfahren zur Herstellung dieses viskoelastischen Produktes.
DE3750733T2 (de) Verfahren zur Herstellung von Hyaluronsäure, dafür benötigte Bakterienstämme und kosmetische Zusammensetzung, welche Hyaluronsäure enthält.
DE69004317D1 (de) Verfahren zur direkten Herstellung von pigmenthaltigem Polyurethanpulver.
DE69109886D1 (de) Verfahren zur Herstellung von humanem Faktor VIII und dessen Analogen.
DE68924619T2 (de) Stereolithographisches Verfahren zur Herstellung von Prothesen.
DE59006474D1 (de) Substituierte (Chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln.
DE68916086T2 (de) Verfahren zur Herstellung von Kohlenstoff/Kohlenstoff-Verbundstoffen.
DE69030162T2 (de) Verfahren zur Herstellung von körnigem Polyarylensulfid mit hohem Molekulargewicht
DE69118428D1 (de) Prozess zur Herstellung von Polyarylensulfiden
DE59008005D1 (de) Verfahren zur Herstellung von hochmolekularen Copolyarylensulfiden.
ATE243322T1 (de) Verfahren zur herstellung von einer stabilen troponin-zubereitung und ihre verwendung als kalibrator/kontrolle in immunoassays
ATE113296T1 (de) Ein neues antibiotikum, mersacidin, ein verfahren zur seiner herstellung und seine verwendung als arzneimittel.
DE69034128D1 (de) Saccharose-Phosphat-Synthase (SPS), ihr Verfahren zur Herstellung, ihr cDNA und Verwendung von cDNA zur Veränderung der SPS-Expression in Pflanzenzellen
DE69123025T2 (de) Verfahren zur Herstellung von optisch aktiven Gamma-butyrolactonderivaten
ATE121420T1 (de) Verfahren zur herstellung von 3-(l-pyroglutamyl)- l-thiazolidin-4-carbonsäure-derivaten.
DE68920351T2 (de) Verfahren zur Herstellung von Indigoverbindungen.
DE69033640T2 (de) Hochrein-Titanwerkstoff, Verfahren zu seiner Herstellung sowie Verwendung als Zerstäubungstarget
DE69009153D1 (de) Verfahren zur Herstellung von künstlichen Diamanten.
DE68911603D1 (de) Verfahren zur Herstellung von 2-Pyrrolidon.
ATE141264T1 (de) Substituierte 2-pyrimidinyl- und 2- triazinylessigsäurederivate, verfahren zu ihrer herstellung und ihre verwendung als mittel mit herbizider, fungizider und pflanzenwachstumsregulierender wirkung
DE69014747D1 (de) Verfahren zur Herstellung von Kaliumtitanarsenat-Einkristallen.
DE68904575D1 (de) Verfahren zur raffinierung von 1,3-dimethyl-2-imidazolidinon und verfahren zur herstellung eines aromatischen polyamids unter verwendung des raffinierten produktes.
DE59008523D1 (de) Verfahren zur Herstellung von Sulfonylharnstoff-Salzen und ihre Verwendung als Herbizide.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee