DE69324678D1 - Verfahren zur typisierung von hcv-isolaten - Google Patents

Verfahren zur typisierung von hcv-isolaten

Info

Publication number
DE69324678D1
DE69324678D1 DE69324678T DE69324678T DE69324678D1 DE 69324678 D1 DE69324678 D1 DE 69324678D1 DE 69324678 T DE69324678 T DE 69324678T DE 69324678 T DE69324678 T DE 69324678T DE 69324678 D1 DE69324678 D1 DE 69324678D1
Authority
DE
Germany
Prior art keywords
hcv isolates
viruses
typing hcv
relates
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69324678T
Other languages
English (en)
Other versions
DE69324678T2 (de
Inventor
Geert Maertens
Lieven Stuyver
Rudi Rossau
Heuverswyn Hugo Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26132445&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69324678(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Publication of DE69324678D1 publication Critical patent/DE69324678D1/de
Application granted granted Critical
Publication of DE69324678T2 publication Critical patent/DE69324678T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
DE69324678T 1992-11-27 1993-11-26 Verfahren zur typisierung von hcv-isolaten Expired - Lifetime DE69324678T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP92403222 1992-11-27
EP93402129 1993-08-31
PCT/EP1993/003325 WO1994012670A2 (en) 1992-11-27 1993-11-26 Process for typing of hcv isolates

Publications (2)

Publication Number Publication Date
DE69324678D1 true DE69324678D1 (de) 1999-06-02
DE69324678T2 DE69324678T2 (de) 1999-12-09

Family

ID=26132445

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69324678T Expired - Lifetime DE69324678T2 (de) 1992-11-27 1993-11-26 Verfahren zur typisierung von hcv-isolaten
DE69334357T Expired - Lifetime DE69334357D1 (de) 1992-11-27 1993-11-26 Nachweis und Typisierung das Hepatitis C Virus (HCV) mittels 5'UTR und NS5 Nukleinsäuresequenzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69334357T Expired - Lifetime DE69334357D1 (de) 1992-11-27 1993-11-26 Nachweis und Typisierung das Hepatitis C Virus (HCV) mittels 5'UTR und NS5 Nukleinsäuresequenzen

Country Status (13)

Country Link
US (8) US5846704A (de)
EP (3) EP0637342B1 (de)
JP (2) JP4251407B2 (de)
AT (2) ATE179459T1 (de)
AU (1) AU681612B2 (de)
CA (1) CA2128528C (de)
DE (2) DE69324678T2 (de)
DK (1) DK0637342T3 (de)
ES (1) ES2133529T3 (de)
GR (1) GR3030641T3 (de)
HK (1) HK1047961A1 (de)
SG (1) SG46456A1 (de)
WO (1) WO1994012670A2 (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG46456A1 (en) * 1992-11-27 1998-02-20 Innogenetics Nv Process for typing of hcv isolates
US7258977B1 (en) * 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
EP0688488A1 (de) * 1993-03-05 1995-12-27 MANKOVITZ, Roy J. Gerät und Verfahren zur Zeitprogrammierung eines Videorecorders mit verkürzten Koden
US7255997B1 (en) 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
US6762024B2 (en) 1993-04-27 2004-07-13 Innogenetics, S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
US5830635A (en) * 1995-03-31 1998-11-03 Agnello; Vincent Method of detecting hepatitis C virus in tissues
US20020081577A1 (en) * 1995-06-06 2002-06-27 Robert L. Kilkuskie Oligonucleotides speciific for hepatitis c virus
JPH11502727A (ja) * 1996-01-26 1999-03-09 イノジェネティックス・ナムローゼ・フェンノートシャップ 逆転写酵素遺伝子における薬剤により誘発された変異の検出方法
ZA973367B (en) 1996-04-19 1997-11-18 Innogenetics Nv Method for typing and detecting HBV.
FR2750505B1 (fr) 1996-06-27 1998-10-16 Appligene Oncor Procede de preparation de supports d'analyse de substances chimiques ou biologiques presentant un ensemble ordonne de zones de reaction
EP1249705A3 (de) 1996-12-31 2003-11-05 Genometrix Genomics Incorporated Multiplex-Analysevorrichtung zur Analyse von Molekülen und zugehöriges Herstellungsverfahren
US7101672B2 (en) * 1998-05-05 2006-09-05 Third Wave Technologies, Inc. Target-dependent reactions using structure-bridging oligonucleotides
IL122299A (en) * 1997-11-25 2003-11-23 Broadcom Corp Video encoding device
US20030096232A1 (en) 1997-12-19 2003-05-22 Kris Richard M. High throughput assay system
EP1008658A4 (de) * 1998-05-19 2002-08-28 Lab Molecular Biophotonics Festphase zur erkennung von nukleinsäuren und verfahren zu deren erkennung
AR020608A1 (es) 1998-07-17 2002-05-22 United Video Properties Inc Un metodo y una disposicion para suministrar a un usuario acceso remoto a una guia de programacion interactiva por un enlace de acceso remoto
EP1099339B1 (de) 1998-07-17 2002-10-09 United Video Properties, Inc. Interaktive fernsehprogrammführung mit mehreren geräten an einem ort
AU2006203092B2 (en) * 1999-02-03 2009-11-12 Ortho-Clinical Diagnostics, Inc. Oligonucleotide primers for efficient detection of hepatitis C virus (HCV) and methods of use thereof
US6638714B1 (en) * 1999-02-03 2003-10-28 Ortho-Clinical Diagnostics, Inc. Oligonucleotide primers for efficient detection of hepatitis C virus (HCV) and methods of use thereof
US6623919B1 (en) * 1999-02-03 2003-09-23 Ortho-Clinical Diagnostics, Inc Oligonucleotide primers for efficient multiplex detection of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) and methods of use thereof
GB0016836D0 (en) 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (1)
US6586584B2 (en) 2001-01-29 2003-07-01 Becton, Dickinson And Company Sequences and methods for detection of Hepatitis C virus
US20040043379A1 (en) * 2001-03-27 2004-03-04 Koji Hashimoto Method of detectingnucleic acid relating to disease
AU2002311897A1 (en) * 2001-05-09 2002-11-18 Third Wave Technologies, Inc. Nucleic acid detection in pooled samples
US7196183B2 (en) * 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
US7877273B2 (en) * 2002-01-08 2011-01-25 Fredric David Abramson System and method for evaluating and providing nutrigenomic data, information and advice
GB0200526D0 (en) * 2002-01-11 2002-02-27 Science And Technology The Methods
FR2855832B1 (fr) 2003-06-03 2007-09-14 Biomerieux Sa Procede de diagnostic et/ou de pronostic d'un syndrome septique
FR2857375B1 (fr) 2003-07-10 2007-11-09 Biomerieux Sa Procede de detection et/ou d'identification de bacteries de genre staphylococcus
EP1536024B1 (de) * 2003-08-29 2016-08-17 Fujirebio Europe N.V. Neue taxonomische gruppe des hepatitis c virus und sequenzen des prototyps
US8124747B2 (en) * 2003-08-29 2012-02-28 Innogenetics HCV clade and prototype sequences thereof
JP5138230B2 (ja) * 2004-01-07 2013-02-06 サード・ウェーブ・テクノロジーズ・インク Ｃ型肝炎ウイルスの遺伝子型の決定方法
WO2005098021A1 (en) * 2004-04-06 2005-10-20 Flinders Technologies Pty. Ltd. Detecting targets using nucleic acids having both a variable region and a conserved region
US8806533B1 (en) 2004-10-08 2014-08-12 United Video Properties, Inc. System and method for using television information codes
FR2881437B1 (fr) 2005-01-31 2010-11-19 Biomerieux Sa Procede pour le diagnostic/pronostic d'un syndrome septique
WO2006104381A1 (en) 2005-03-30 2006-10-05 Labo Bio-Medical Investments Identification of beta-papillomavirus dna by type-specific reverse hybridization
US8067208B2 (en) * 2005-06-30 2011-11-29 Roche Molecular Systems, Inc. Probes and methods for hepatitis C virus typing using multidimensional probe analysis
WO2007059348A2 (en) * 2005-11-17 2007-05-24 Third Wave Technologies, Inc. Compositions and methods for detecting an hcv-1 subtype
US7544473B2 (en) * 2006-01-23 2009-06-09 Population Genetics Technologies Ltd. Nucleic acid analysis using sequence tokens
FR2906537A1 (fr) 2006-09-28 2008-04-04 Biomerieux Sa Procede de diagnostic in vitro du cancer broncho-pulmonaire par detection des transcrits majoritaires alternatifs du gene klk8 codant la kallicreine 8 et son utilisation pour le pronostic de survie
EP2121991A2 (de) 2006-10-20 2009-11-25 Innogenetics N.V. Methodik zur analyse von sequenzvariationen innerhalb des hcv-ns3/4a-genombereichs
EP2463389A1 (de) 2006-10-20 2012-06-13 Innogenetics N.V. Methodik zur Analyse von Sequenzvariationen innerhalb des HCV-NS5B-Genombereichs
US8418206B2 (en) 2007-03-22 2013-04-09 United Video Properties, Inc. User defined rules for assigning destinations of content
EP2236624B1 (de) * 2007-08-09 2012-11-07 Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Molekulyarnoi Biologi Im. V.A. Engelgardta Rossiiskoi Akademii Nauk Verfahren zur identifizierung des genotyps und subtyps von hepatitis-c-virus auf einem biologischen mikrochip
US8601526B2 (en) 2008-06-13 2013-12-03 United Video Properties, Inc. Systems and methods for displaying media content and media guidance information
KR101755037B1 (ko) 2008-12-29 2017-07-19 주식회사 엘지화학 핵산 염색제를 이용한 실시간 중합효소 연쇄반응을 통한 ｈｃｖ 검출방법
US20100240049A1 (en) 2009-01-16 2010-09-23 Cepheid Methods of Detecting Cervical Cancer
EP2379752B1 (de) 2009-01-19 2015-09-30 Biomérieux S.A. Verfahren zur bestimmung der anfälligkeit eines subjekts für eine nosokomiale infektion und zur prognose der entwicklung eines septischen syndroms
US20100323344A1 (en) * 2009-06-18 2010-12-23 Ferguson Monique R Detection of hepatitis C virus RNA
US9204193B2 (en) 2010-05-14 2015-12-01 Rovi Guides, Inc. Systems and methods for media detection and filtering using a parental control logging application
WO2011150976A1 (en) 2010-06-04 2011-12-08 bioMérieux Method and kit for the prognosis of colorectal cancer
US9110079B2 (en) 2010-09-29 2015-08-18 Biomerieux Method and kit for establishing an in vitro prognosis on a patient exhibiting SIRS
FR2970975B1 (fr) 2011-01-27 2016-11-04 Biomerieux Sa Procede et kit pour determiner in vitro le statut immunitaire d'un individu
WO2012129758A1 (en) 2011-03-25 2012-10-04 Biomerieux Method and kit for determining in vitro probability for individual to suffer from colorectal cancer
ES2640570T3 (es) * 2012-10-18 2017-11-03 F. Hoffmann-La Roche Ag Ensayo de doble sonda para la detección de VHC
FR3000966B1 (fr) 2013-01-11 2016-10-28 Biomerieux Sa Procede pour etablir in vitro un pronostic de severite chez un patient en choc septique
WO2014187308A2 (zh) 2013-05-21 2014-11-27 生物梅里埃股份公司 一种大肠癌预后试剂盒
WO2018075633A2 (en) * 2016-10-19 2018-04-26 Gen-Probe Incorporated Compositions and methods for detecting or quantifying hepatitis c virus
EP3643792B1 (de) 2018-10-24 2021-09-15 Fujirebio Europe N.V. Nachweis und analyse von sequenzvariationen in einer ziel-nukleinsäure

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8810400D0 (en) * 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
JPH02167081A (ja) * 1988-12-21 1990-06-27 Tetsuo Nakamura 非Ａ非Ｂ型肝炎ウイルスゲノムＲＮＡ、ｃＤＮＡおよびウイルス抗原蛋白質
US5176994A (en) * 1988-12-21 1993-01-05 Immuno Japan Inc. Non-A, Non-B hepatitis virus genome RNA, cDNA and virus antigen protein
US5629158A (en) 1989-03-22 1997-05-13 Cemu Bitecknik Ab Solid phase diagnosis of medical conditions
US5043272A (en) * 1989-04-27 1991-08-27 Life Technologies, Incorporated Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers
JP2802125B2 (ja) * 1989-06-23 1998-09-24 キヤノン株式会社 核酸の検出方法
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
GB8924989D0 (en) * 1989-11-06 1989-12-28 Scotgen Ltd Method and device for the detection of antibiotic resistance
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
US5629153A (en) * 1990-01-10 1997-05-13 Chiron Corporation Use of DNA-dependent RNA polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
EP0461863A1 (de) * 1990-06-12 1991-12-18 Immuno Japan Inc. Oligonukleotid-Primer und ihre Anwendung zum Nachweis von non-A, non-B-Hepatitisvirus mit grosser Genauigkeit
ATE150086T1 (de) * 1990-07-11 1997-03-15 Shionogi & Co Cdns-sequenz und detektion des hepatitis c-virus
CZ282573B6 (cs) * 1990-08-10 1997-08-13 Chiron Corporation Způsob detekce HCV sekvence, souprava a reakční činidlo pro detekci HCV
US5620852A (en) 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
EP0834576B1 (de) * 1990-12-06 2002-01-16 Affymetrix, Inc. (a Delaware Corporation) Detektion von Nukleinsäuresequenzen
EP0511559A1 (de) * 1991-04-30 1992-11-04 F.Hoffmann-La Roche & Co. Aktiengesellschaft Reagens für eine Oligonukleotidprobe
ES2207633T3 (es) 1991-05-08 2004-06-01 Chiron Corporation Secuencias genomicas del vhc para diagnostico y tratamiento.
US6190864B1 (en) * 1991-05-08 2001-02-20 Chiron Corporation HCV genomic sequences for diagnostics and therapeutics
US5428145A (en) * 1991-08-09 1995-06-27 Immuno Japan, Inc. Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
ES2198514T3 (es) * 1991-08-27 2004-02-01 F. Hoffmann-La Roche Ag Cebadores y sondas para la deteccion de la hepatitis c.
US5427909A (en) * 1991-09-09 1995-06-27 Immuno Japan Inc. Oligonucleotides and determination system of HCV genotypes
JPH06502770A (ja) 1991-09-12 1994-03-31 シーダーズ−サイナイ・メディカル・センター Ｃ型肝炎ウイルスｒｎａの直接検出法
US5173994A (en) * 1992-01-14 1992-12-29 The United States Of America As Represented By The Secretary Of Agriculture Fiber cleaning apparatus with air flow deflector
WO1993023569A1 (en) * 1992-05-11 1993-11-25 Ribozyme Pharmaceuticals, Inc. Method and reagent for inhibiting viral replication
JPH06153961A (ja) 1992-11-27 1994-06-03 Imuno Japan:Kk Ｃ型肝炎ウイルス部分遺伝子、ならびにｃ型肝炎ウイルス遺 伝子の高感度検出法
SG46456A1 (en) * 1992-11-27 1998-02-20 Innogenetics Nv Process for typing of hcv isolates
US5820852A (en) * 1996-11-26 1998-10-13 The Proctor & Gamble Company Oral compositions containing fluoride, pyrophosphate, and peroxide

Also Published As

Publication number Publication date
US6548244B2 (en) 2003-04-15
US20030036053A1 (en) 2003-02-20
HK1047961A1 (zh) 2003-03-14
US20020106638A1 (en) 2002-08-08
EP0905258A3 (de) 2001-01-31
US6051696A (en) 2000-04-18
CA2128528C (en) 2012-02-14
EP1197568B1 (de) 2011-04-27
SG46456A1 (en) 1998-02-20
US20040191768A1 (en) 2004-09-30
AU5628294A (en) 1994-06-22
JP4251407B2 (ja) 2009-04-08
DE69334357D1 (de) 2011-06-09
EP0637342A1 (de) 1995-02-08
DE69324678T2 (de) 1999-12-09
US6891026B2 (en) 2005-05-10
JPH07503143A (ja) 1995-04-06
WO1994012670A2 (en) 1994-06-09
EP0905258A2 (de) 1999-03-31
ES2133529T3 (es) 1999-09-16
US6171784B1 (en) 2001-01-09
WO1994012670A3 (en) 1994-07-21
US5846704A (en) 1998-12-08
DK0637342T3 (da) 1999-11-01
ATE179459T1 (de) 1999-05-15
US7258982B2 (en) 2007-08-21
US6887985B2 (en) 2005-05-03
CA2128528A1 (en) 1994-06-09
AU681612B2 (en) 1997-09-04
US6495670B1 (en) 2002-12-17
EP1197568A3 (de) 2004-04-14
EP1197568A2 (de) 2002-04-17
EP0637342B1 (de) 1999-04-28
ATE507312T1 (de) 2011-05-15
US20020168626A1 (en) 2002-11-14
GR3030641T3 (en) 1999-10-29
JP2005040145A (ja) 2005-02-17

Similar Documents

Publication Publication Date Title
ATE179459T1 (de) Verfahren zur typisierung von hcv-isolaten
SG50563A1 (en) New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents
DE69434117D1 (de) Verfahren zur typisierung von hepatitis c viren und dafür zu verwendende reagenzien
DE3775239D1 (de) Verfahren zur massenpolymerisation von butadien.
DE69325452T2 (de) Verfahren zur herstellung von (s)-3-amino-1-substituiert-pirrolidine
DE3873087T2 (de) Verfahren zur desodorierung und reinigung von agressiven, uebelriechenden gasen.
DE59303465D1 (de) Verfahren zur Reaktivierung eines bei der Herstellung von 1,1,1,2,3,3,3-Heptafluorpropan (R 227) eingesetzten Aktivkohle-Katalysators
DE3767208D1 (de) Verfahren zur herstellung von 4-acetalen des butendial-(1,4) und neue acetale des butendial-(1,4).
DE59407675D1 (de) Verfahren zur Herstellung von 6H-Dibenz-(c,e)(1,2)-oxaphosphorin-6-on
DE59007794D1 (de) Verfahren zur Herstellung von 2-Chlor-5-chlormethyl-pyridin und neue Zwischenprodukte.
DE68912809D1 (de) Verfahren zur Herstellung von Bis(2,2,6,6-tetramethyl-4-piperidyl)amin.
DE3686909T2 (de) Lymphotoxin-dns, lymphotoxin-expressionsvektor, lymphotoxin-expressionsvektor enthaltender transformant und verfahren zur herstellung von lymphotoxin.
DE68911603D1 (de) Verfahren zur Herstellung von 2-Pyrrolidon.
DE68919047D1 (de) Verfahren zur Herstellung von substituierten Aminoanthrachinonen.
DE69009394D1 (de) Verfahren zur Herstellung von 3-Cyano-3,5,5-trimethyl-1-cyclohexanon.
DE3688854T2 (de) Verfahren zur Herstellung von Polythiobisphenolen und Verfahren zur Herstellung von Mercaptophenolen durch Hydrogenolyse der Polythiobisphenole.
DE69007028D1 (de) Verfahren zur Herstellung von 3,4-Epoxybutyrat und Zwischenprodukte dafür.
ATE27447T1 (de) Verfahren zur herstellung von ungesaettigten dichlorisobutenen.
DE3671007D1 (de) Verfahren zur herstellung von kohlefaserverstaerkten kohlenstoffverbundwerkstoffen.
DE59303525D1 (de) Verfahren zur Herstellung von N-(2-Hydroxypropyl)-2,6-dimethylmorpholin
AT386079B (de) Verfahren zum nachweis von antikoerpern, und mittel zum nachweis von antikoerpern und verfahren zur herstellung des mittels
DE3762339D1 (de) Verfahren zur reinigung von 1-amino-5-hydroxynaphthalin enthaltendem 1,5-diaminonaphthalin.
IL88420A (en) Polypeptide comprising an amino acid sequence encoded by the hepatitis C virus genome a composition comprising said polypeptide immunoassays using said polypeptide antibodies against said polypeptide a DNA polynucleotide encoding said polypeptide kits comprising said polypeptide or said polynucleotide and a method for performing a reaction using said polynucleotide
DE59003424D1 (de) Verfahren zur Herstellung von 2- und 4-Amino-thiophenolen.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings