DE69328354T2 - Verbesserungen in oder bezüglich zu kontrastmittel - Google Patents
Verbesserungen in oder bezüglich zu kontrastmittelInfo
- Publication number
- DE69328354T2 DE69328354T2 DE69328354T DE69328354T DE69328354T2 DE 69328354 T2 DE69328354 T2 DE 69328354T2 DE 69328354 T DE69328354 T DE 69328354T DE 69328354 T DE69328354 T DE 69328354T DE 69328354 T2 DE69328354 T2 DE 69328354T2
- Authority
- DE
- Germany
- Prior art keywords
- surfactant
- microparticulate
- contrasting agents
- carbohydrate
- contrast
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001720 carbohydrates Chemical class 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 239000002872 contrast media Substances 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 229930182830 galactose Natural products 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 238000002604 ultrasonography Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/225—Microparticles, microcapsules
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929200388A GB9200388D0 (en) | 1992-01-09 | 1992-01-09 | Improvements in or relating to contrast agents |
PCT/EP1993/000027 WO1993013808A2 (en) | 1992-01-09 | 1993-01-08 | Improvements in or relating to contrast agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69328354D1 DE69328354D1 (de) | 2000-05-18 |
DE69328354T2 true DE69328354T2 (de) | 2000-12-14 |
Family
ID=10708317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69328354T Expired - Fee Related DE69328354T2 (de) | 1992-01-09 | 1993-01-08 | Verbesserungen in oder bezüglich zu kontrastmittel |
Country Status (16)
Country | Link |
---|---|
US (5) | US5558856A (de) |
EP (2) | EP0972527A3 (de) |
JP (1) | JPH07505136A (de) |
AT (1) | ATE191646T1 (de) |
AU (2) | AU676147B2 (de) |
CA (1) | CA2127705C (de) |
DE (1) | DE69328354T2 (de) |
DK (1) | DK0620744T3 (de) |
ES (1) | ES2144454T3 (de) |
GB (1) | GB9200388D0 (de) |
GR (1) | GR3033902T3 (de) |
HK (1) | HK1001994A1 (de) |
NO (1) | NO311330B1 (de) |
PT (1) | PT620744E (de) |
SG (1) | SG52338A1 (de) |
WO (1) | WO1993013808A2 (de) |
Families Citing this family (100)
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US5656211A (en) | 1989-12-22 | 1997-08-12 | Imarx Pharmaceutical Corp. | Apparatus and method for making gas-filled vesicles of optimal size |
US5776429A (en) | 1989-12-22 | 1998-07-07 | Imarx Pharmaceutical Corp. | Method of preparing gas-filled microspheres using a lyophilized lipids |
US6088613A (en) | 1989-12-22 | 2000-07-11 | Imarx Pharmaceutical Corp. | Method of magnetic resonance focused surgical and therapeutic ultrasound |
US5469854A (en) | 1989-12-22 | 1995-11-28 | Imarx Pharmaceutical Corp. | Methods of preparing gas-filled liposomes |
USRE39146E1 (en) | 1990-04-02 | 2006-06-27 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
US7083778B2 (en) * | 1991-05-03 | 2006-08-01 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
US6613306B1 (en) | 1990-04-02 | 2003-09-02 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
IN172208B (de) | 1990-04-02 | 1993-05-01 | Sint Sa | |
US20010024638A1 (en) * | 1992-11-02 | 2001-09-27 | Michel Schneider | Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof |
US5445813A (en) * | 1992-11-02 | 1995-08-29 | Bracco International B.V. | Stable microbubble suspensions as enhancement agents for ultrasound echography |
US5578292A (en) | 1991-11-20 | 1996-11-26 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
US20040208826A1 (en) * | 1990-04-02 | 2004-10-21 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
US6989141B2 (en) * | 1990-05-18 | 2006-01-24 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
US20030194376A1 (en) * | 1990-05-18 | 2003-10-16 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
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US5205290A (en) | 1991-04-05 | 1993-04-27 | Unger Evan C | Low density microspheres and their use as contrast agents for computed tomography |
US5874062A (en) | 1991-04-05 | 1999-02-23 | Imarx Pharmaceutical Corp. | Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents |
MX9205298A (es) | 1991-09-17 | 1993-05-01 | Steven Carl Quay | Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido |
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-
1992
- 1992-01-09 GB GB929200388A patent/GB9200388D0/en active Pending
-
1993
- 1993-01-08 DK DK93902156T patent/DK0620744T3/da active
- 1993-01-08 SG SG1996003035A patent/SG52338A1/en unknown
- 1993-01-08 AU AU33484/93A patent/AU676147B2/en not_active Ceased
- 1993-01-08 DE DE69328354T patent/DE69328354T2/de not_active Expired - Fee Related
- 1993-01-08 US US08/256,149 patent/US5558856A/en not_active Expired - Lifetime
- 1993-01-08 ES ES93902156T patent/ES2144454T3/es not_active Expired - Lifetime
- 1993-01-08 CA CA002127705A patent/CA2127705C/en not_active Expired - Lifetime
- 1993-01-08 EP EP99203253A patent/EP0972527A3/de not_active Withdrawn
- 1993-01-08 PT PT93902156T patent/PT620744E/pt unknown
- 1993-01-08 JP JP5512124A patent/JPH07505136A/ja active Pending
- 1993-01-08 WO PCT/EP1993/000027 patent/WO1993013808A2/en not_active Application Discontinuation
- 1993-01-08 EP EP93902156A patent/EP0620744B1/de not_active Revoked
- 1993-01-08 AT AT93902156T patent/ATE191646T1/de not_active IP Right Cessation
-
1994
- 1994-07-07 NO NO19942561A patent/NO311330B1/no not_active IP Right Cessation
-
1995
- 1995-06-07 US US08/478,037 patent/US5827502A/en not_active Expired - Fee Related
-
1997
- 1997-06-06 AU AU24763/97A patent/AU2476397A/en not_active Abandoned
-
1998
- 1998-02-05 HK HK98100862A patent/HK1001994A1/xx not_active IP Right Cessation
-
2000
- 2000-07-05 GR GR20000401587T patent/GR3033902T3/el not_active IP Right Cessation
-
2002
- 2002-02-08 US US10/072,655 patent/US20030059373A1/en not_active Abandoned
-
2004
- 2004-04-07 US US10/820,428 patent/US20050031543A1/en not_active Abandoned
-
2005
- 2005-02-10 US US11/055,544 patent/US20050196342A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0620744A1 (de) | 1994-10-26 |
EP0972527A2 (de) | 2000-01-19 |
AU2476397A (en) | 1997-08-21 |
SG52338A1 (en) | 1998-09-28 |
WO1993013808A2 (en) | 1993-07-22 |
AU3348493A (en) | 1993-08-03 |
GR3033902T3 (en) | 2000-11-30 |
GB9200388D0 (en) | 1992-02-26 |
CA2127705A1 (en) | 1993-07-22 |
ES2144454T3 (es) | 2000-06-16 |
WO1993013808A3 (en) | 1993-10-14 |
ATE191646T1 (de) | 2000-04-15 |
NO942561D0 (no) | 1994-07-07 |
US20050196342A1 (en) | 2005-09-08 |
JPH07505136A (ja) | 1995-06-08 |
EP0620744B1 (de) | 2000-04-12 |
US5558856A (en) | 1996-09-24 |
US20050031543A1 (en) | 2005-02-10 |
CA2127705C (en) | 2000-11-21 |
NO942561L (no) | 1994-07-07 |
DE69328354D1 (de) | 2000-05-18 |
PT620744E (pt) | 2000-07-31 |
US5827502A (en) | 1998-10-27 |
AU676147B2 (en) | 1997-03-06 |
DK0620744T3 (da) | 2000-09-11 |
EP0972527A3 (de) | 2000-08-16 |
HK1001994A1 (en) | 1998-07-24 |
NO311330B1 (no) | 2001-11-19 |
US20030059373A1 (en) | 2003-03-27 |
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