DE69328838T2 - Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten - Google Patents
Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthaltenInfo
- Publication number
- DE69328838T2 DE69328838T2 DE69328838T DE69328838T DE69328838T2 DE 69328838 T2 DE69328838 T2 DE 69328838T2 DE 69328838 T DE69328838 T DE 69328838T DE 69328838 T DE69328838 T DE 69328838T DE 69328838 T2 DE69328838 T2 DE 69328838T2
- Authority
- DE
- Germany
- Prior art keywords
- etodolac
- pain
- optically pure
- methods
- analgetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85322292A | 1992-03-13 | 1992-03-13 | |
US2983493A | 1993-03-11 | 1993-03-11 | |
PCT/US1993/002282 WO1993017680A1 (en) | 1992-03-13 | 1993-03-12 | Antipyretic and analgesic methods and compositions containing optically pure r-etodolac |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69328838D1 DE69328838D1 (de) | 2000-07-13 |
DE69328838T2 true DE69328838T2 (de) | 2000-10-12 |
Family
ID=26705391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69328838T Expired - Fee Related DE69328838T2 (de) | 1992-03-13 | 1993-03-12 | Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten |
Country Status (9)
Country | Link |
---|---|
US (1) | US5561151A (de) |
EP (1) | EP0727994B1 (de) |
JP (1) | JPH07506817A (de) |
AT (1) | ATE193648T1 (de) |
AU (2) | AU3806393A (de) |
CA (1) | CA2131992A1 (de) |
DE (1) | DE69328838T2 (de) |
DK (1) | DK0727994T3 (de) |
WO (1) | WO1993017680A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA964928B (en) * | 1995-06-13 | 1997-12-10 | American Home Prod | Oral formulations of S(+)-etodolac. |
EP1082966A4 (de) * | 1998-05-15 | 2004-07-21 | Wakamoto Pharma Co Ltd | Entzündungshemmende augentropfen |
ATE315392T1 (de) | 1998-07-09 | 2006-02-15 | Francis A Nardella | Zusammensetzungen zur behandlung chronischer lymphatischer leukämie |
US7361680B2 (en) * | 1999-07-23 | 2008-04-22 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US7105560B1 (en) | 1999-07-23 | 2006-09-12 | The Regents Of The University Of California | Use of etodolac in the treatment of multiple myeloma |
US7129262B2 (en) * | 1999-07-23 | 2006-10-31 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US6545034B1 (en) | 1999-07-23 | 2003-04-08 | The Regents Of The University Of California | Use of etodolac for the treatment of chronic lymphocytic leukemia |
US7151100B1 (en) * | 1999-07-23 | 2006-12-19 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US20040152672A1 (en) * | 2000-08-09 | 2004-08-05 | Carson Dennis A. | Indole compounds useful for the treatment of cancer |
US6534676B2 (en) * | 2001-01-31 | 2003-03-18 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same |
US6596686B2 (en) | 2001-03-12 | 2003-07-22 | International Flavors & Fragrances Inc. | Use of dihydropyrans as fragrance Material |
US7601846B2 (en) * | 2001-06-26 | 2009-10-13 | The Regents Of The University Of California | Compounds having activity as inhibitors of apoptosis |
US20030232794A1 (en) * | 2001-06-26 | 2003-12-18 | Cottam Howard B. | Use of STAT-6 inhibitors as therapeutic agents |
US20030027867A1 (en) * | 2001-06-29 | 2003-02-06 | Myriad Genetics, Incorporated | Use of R-NSAID compounds for anti-HIV treatment |
TW200400963A (en) | 2002-05-21 | 2004-01-16 | Wyeth Corp | R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease |
US7211599B2 (en) * | 2002-09-19 | 2007-05-01 | The Regents Of The University Of California | Use of etodolac to treat hyperplasia |
US7446122B2 (en) * | 2003-10-02 | 2008-11-04 | Cephalon, Inc. | Substituted indole derivatives |
CN101043922A (zh) | 2004-08-19 | 2007-09-26 | Igt公司 | 具有多个提供奖金奖励的游戏机的游戏系统 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3904682A (en) * | 1967-01-13 | 1975-09-09 | Syntex Corp | 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid |
NL170852C (nl) * | 1968-03-27 | 1983-01-03 | Ciba Geigy Ag | Werkwijze ter bereiding van farmaceutische preparaten en werkwijze ter bereiding van anti-inflammatoir werkzaam p-isoindolinylfenylazijnzuur en van derivaten hiervan. |
FR2068425B1 (de) * | 1969-11-12 | 1973-01-12 | Roussel Uclaf | |
US3843681A (en) * | 1971-06-01 | 1974-10-22 | American Home Prod | 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives |
US3896145A (en) * | 1972-07-24 | 1975-07-22 | Hoffmann La Roche | Carbazoles |
US4501899A (en) * | 1983-08-16 | 1985-02-26 | American Home Products Corporation | Resolution of (+)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid using cholesteryl aniline |
US4520203A (en) * | 1983-08-16 | 1985-05-28 | American Home Products Corporation | Resolution of (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid using cinchonine |
US4515961A (en) * | 1983-08-16 | 1985-05-07 | American Home Products Corporation | Resolution of (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4,-b] indole-1-acetic acid using enrichment crystallization |
US4544757A (en) * | 1984-02-16 | 1985-10-01 | American Home Products Corporation | Process for the resolution of pyrano[3,4-b]indole-1-acetic acids |
US4962124A (en) * | 1987-11-17 | 1990-10-09 | Analgesic Associates | Onset-hastened/enhanced antipyretic response |
US4927854A (en) * | 1987-12-24 | 1990-05-22 | Analgesic Associates | Sustained/enhanced analgesia |
DE3824353A1 (de) * | 1988-07-19 | 1990-01-25 | Paz Arzneimittelentwicklung | Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren |
-
1993
- 1993-03-12 CA CA002131992A patent/CA2131992A1/en not_active Abandoned
- 1993-03-12 DK DK93907465T patent/DK0727994T3/da active
- 1993-03-12 AU AU38063/93A patent/AU3806393A/en not_active Abandoned
- 1993-03-12 DE DE69328838T patent/DE69328838T2/de not_active Expired - Fee Related
- 1993-03-12 WO PCT/US1993/002282 patent/WO1993017680A1/en active IP Right Grant
- 1993-03-12 AT AT93907465T patent/ATE193648T1/de not_active IP Right Cessation
- 1993-03-12 JP JP5516026A patent/JPH07506817A/ja active Pending
- 1993-03-12 EP EP93907465A patent/EP0727994B1/de not_active Expired - Lifetime
-
1995
- 1995-01-04 US US08/368,735 patent/US5561151A/en not_active Expired - Fee Related
-
1997
- 1997-10-09 AU AU39992/97A patent/AU707780B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
DK0727994T3 (da) | 2000-08-07 |
AU707780B2 (en) | 1999-07-22 |
AU3999297A (en) | 1997-12-18 |
US5561151A (en) | 1996-10-01 |
CA2131992A1 (en) | 1993-09-16 |
DE69328838D1 (de) | 2000-07-13 |
AU3806393A (en) | 1993-10-05 |
EP0727994A4 (de) | 1997-01-15 |
EP0727994B1 (de) | 2000-06-07 |
ATE193648T1 (de) | 2000-06-15 |
JPH07506817A (ja) | 1995-07-27 |
WO1993017680A1 (en) | 1993-09-16 |
EP0727994A1 (de) | 1996-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |