DE69328838T2 - Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten - Google Patents

Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten

Info

Publication number
DE69328838T2
DE69328838T2 DE69328838T DE69328838T DE69328838T2 DE 69328838 T2 DE69328838 T2 DE 69328838T2 DE 69328838 T DE69328838 T DE 69328838T DE 69328838 T DE69328838 T DE 69328838T DE 69328838 T2 DE69328838 T2 DE 69328838T2
Authority
DE
Germany
Prior art keywords
etodolac
pain
optically pure
methods
analgetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69328838T
Other languages
English (en)
Other versions
DE69328838D1 (de
Inventor
James W Young
Nancy M Gray
William J Wechter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunovion Pharmaceuticals Inc
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Application granted granted Critical
Publication of DE69328838D1 publication Critical patent/DE69328838D1/de
Publication of DE69328838T2 publication Critical patent/DE69328838T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
DE69328838T 1992-03-13 1993-03-12 Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten Expired - Fee Related DE69328838T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85322292A 1992-03-13 1992-03-13
US2983493A 1993-03-11 1993-03-11
PCT/US1993/002282 WO1993017680A1 (en) 1992-03-13 1993-03-12 Antipyretic and analgesic methods and compositions containing optically pure r-etodolac

Publications (2)

Publication Number Publication Date
DE69328838D1 DE69328838D1 (de) 2000-07-13
DE69328838T2 true DE69328838T2 (de) 2000-10-12

Family

ID=26705391

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69328838T Expired - Fee Related DE69328838T2 (de) 1992-03-13 1993-03-12 Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten

Country Status (9)

Country Link
US (1) US5561151A (de)
EP (1) EP0727994B1 (de)
JP (1) JPH07506817A (de)
AT (1) ATE193648T1 (de)
AU (2) AU3806393A (de)
CA (1) CA2131992A1 (de)
DE (1) DE69328838T2 (de)
DK (1) DK0727994T3 (de)
WO (1) WO1993017680A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA964928B (en) * 1995-06-13 1997-12-10 American Home Prod Oral formulations of S(+)-etodolac.
EP1082966A4 (de) * 1998-05-15 2004-07-21 Wakamoto Pharma Co Ltd Entzündungshemmende augentropfen
ATE315392T1 (de) 1998-07-09 2006-02-15 Francis A Nardella Zusammensetzungen zur behandlung chronischer lymphatischer leukämie
US7361680B2 (en) * 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US7129262B2 (en) * 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6545034B1 (en) 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7151100B1 (en) * 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US20040152672A1 (en) * 2000-08-09 2004-08-05 Carson Dennis A. Indole compounds useful for the treatment of cancer
US6534676B2 (en) * 2001-01-31 2003-03-18 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same
US6596686B2 (en) 2001-03-12 2003-07-22 International Flavors & Fragrances Inc. Use of dihydropyrans as fragrance Material
US7601846B2 (en) * 2001-06-26 2009-10-13 The Regents Of The University Of California Compounds having activity as inhibitors of apoptosis
US20030232794A1 (en) * 2001-06-26 2003-12-18 Cottam Howard B. Use of STAT-6 inhibitors as therapeutic agents
US20030027867A1 (en) * 2001-06-29 2003-02-06 Myriad Genetics, Incorporated Use of R-NSAID compounds for anti-HIV treatment
TW200400963A (en) 2002-05-21 2004-01-16 Wyeth Corp R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease
US7211599B2 (en) * 2002-09-19 2007-05-01 The Regents Of The University Of California Use of etodolac to treat hyperplasia
US7446122B2 (en) * 2003-10-02 2008-11-04 Cephalon, Inc. Substituted indole derivatives
CN101043922A (zh) 2004-08-19 2007-09-26 Igt公司 具有多个提供奖金奖励的游戏机的游戏系统

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
NL170852C (nl) * 1968-03-27 1983-01-03 Ciba Geigy Ag Werkwijze ter bereiding van farmaceutische preparaten en werkwijze ter bereiding van anti-inflammatoir werkzaam p-isoindolinylfenylazijnzuur en van derivaten hiervan.
FR2068425B1 (de) * 1969-11-12 1973-01-12 Roussel Uclaf
US3843681A (en) * 1971-06-01 1974-10-22 American Home Prod 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives
US3896145A (en) * 1972-07-24 1975-07-22 Hoffmann La Roche Carbazoles
US4501899A (en) * 1983-08-16 1985-02-26 American Home Products Corporation Resolution of (+)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid using cholesteryl aniline
US4520203A (en) * 1983-08-16 1985-05-28 American Home Products Corporation Resolution of (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid using cinchonine
US4515961A (en) * 1983-08-16 1985-05-07 American Home Products Corporation Resolution of (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4,-b] indole-1-acetic acid using enrichment crystallization
US4544757A (en) * 1984-02-16 1985-10-01 American Home Products Corporation Process for the resolution of pyrano[3,4-b]indole-1-acetic acids
US4962124A (en) * 1987-11-17 1990-10-09 Analgesic Associates Onset-hastened/enhanced antipyretic response
US4927854A (en) * 1987-12-24 1990-05-22 Analgesic Associates Sustained/enhanced analgesia
DE3824353A1 (de) * 1988-07-19 1990-01-25 Paz Arzneimittelentwicklung Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren

Also Published As

Publication number Publication date
DK0727994T3 (da) 2000-08-07
AU707780B2 (en) 1999-07-22
AU3999297A (en) 1997-12-18
US5561151A (en) 1996-10-01
CA2131992A1 (en) 1993-09-16
DE69328838D1 (de) 2000-07-13
AU3806393A (en) 1993-10-05
EP0727994A4 (de) 1997-01-15
EP0727994B1 (de) 2000-06-07
ATE193648T1 (de) 2000-06-15
JPH07506817A (ja) 1995-07-27
WO1993017680A1 (en) 1993-09-16
EP0727994A1 (de) 1996-08-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee