DE69331839T2 - Schnellösliche Tablette und ihre Herstellung - Google Patents

Schnellösliche Tablette und ihre Herstellung

Info

Publication number
DE69331839T2
DE69331839T2 DE69331839T DE69331839T DE69331839T2 DE 69331839 T2 DE69331839 T2 DE 69331839T2 DE 69331839 T DE69331839 T DE 69331839T DE 69331839 T DE69331839 T DE 69331839T DE 69331839 T2 DE69331839 T2 DE 69331839T2
Authority
DE
Germany
Prior art keywords
dissolving tablet
carbohydrate
fast dissolving
tablet
fast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331839T
Other languages
English (en)
Other versions
DE69331839D1 (de
Inventor
Tadashi Makino
Masayuki Yamada
Jun-Ichi Kikuta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11835174&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69331839(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69331839D1 publication Critical patent/DE69331839D1/de
Application granted granted Critical
Publication of DE69331839T2 publication Critical patent/DE69331839T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
DE69331839T 1992-01-29 1993-01-27 Schnellösliche Tablette und ihre Herstellung Expired - Lifetime DE69331839T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1351192 1992-01-29

Publications (2)

Publication Number Publication Date
DE69331839D1 DE69331839D1 (de) 2002-05-29
DE69331839T2 true DE69331839T2 (de) 2002-12-12

Family

ID=11835174

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331839T Expired - Lifetime DE69331839T2 (de) 1992-01-29 1993-01-27 Schnellösliche Tablette und ihre Herstellung

Country Status (8)

Country Link
US (2) US5501861A (de)
EP (1) EP0553777B1 (de)
JP (2) JP3069458B2 (de)
KR (1) KR100258223B1 (de)
AT (1) ATE216577T1 (de)
CA (1) CA2088334C (de)
DE (1) DE69331839T2 (de)
TW (1) TW249756B (de)

Families Citing this family (212)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2650493B2 (ja) * 1992-02-18 1997-09-03 日本新薬株式会社 速溶錠
CA2130487A1 (en) * 1992-02-18 1993-08-19 Kouichi Nakamichi Fast soluble tablet
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
CA2179382C (en) * 1994-01-31 2009-11-10 Takao Mizumoto Intrabuccally dissolving compressed moldings and production process thereof
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
DE4403943A1 (de) * 1994-02-08 1995-08-10 Hexal Pharma Gmbh Orale Azrneimittelzubereitung mit Diclofenac-Natrium
US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)
US5837287A (en) * 1994-10-28 1998-11-17 R P Scherer Corporation Process for preparing solid pharmaceutical dosage forms
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
US5762961A (en) * 1996-02-09 1998-06-09 Quadrant Holdings Cambridge Ltd. Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof
NZ512609A (en) * 1996-02-29 2003-03-28 Fujisawa Pharmaceutical Co Synthetic sweeteners, their production and uses thereof
DE69739967D1 (de) 1996-06-14 2010-09-30 Kyowa Hakko Kirin Co Ltd Eine im Mund schnell zerfallende Tablette
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
AU3444297A (en) * 1996-07-12 1998-02-09 Novartis Consumer Health S.A. Oral pharmaceutical combinations of nsaids with terpenoids
EP0922464B1 (de) 1996-07-12 2005-03-30 Daiichi Pharmaceutical Co., Ltd. Schnell zerfallende, druckgeformte materialien sowie prozess zu deren herstellung
US5846568A (en) * 1996-09-19 1998-12-08 Xyrofin Oy Directly compressible lactitol and method
EP0839526A3 (de) * 1996-10-31 1999-01-07 Takeda Chemical Industries, Ltd. Festes pharmazeutisches Präparat mit schneller Auflösungs- oder Disintegrationeigenschaften
JP3819441B2 (ja) * 1997-01-09 2006-09-06 森永乳業株式会社 ラクトフェリン錠剤
ES2273409T3 (es) 1997-03-28 2007-05-01 Eisai Co., Ltd. Medicamento oral que previene el sabor desagradable y similar.
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
US5939091A (en) * 1997-05-20 1999-08-17 Warner Lambert Company Method for making fast-melt tablets
JP4939680B2 (ja) * 1997-05-27 2012-05-30 武田薬品工業株式会社 固形製剤
TW580397B (en) 1997-05-27 2004-03-21 Takeda Chemical Industries Ltd Solid preparation
EP1001748B1 (de) * 1997-07-25 2006-04-19 Alpex Pharma S.A. Verfahren zur herstellung eines granulates, geeignet zur herstellung schnell-freisetzender, im mund löslicher tabletten
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
JPH11137208A (ja) * 1997-11-14 1999-05-25 Nikken Chem Co Ltd 口腔内速溶性固形物及びその製造方法
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US6413541B1 (en) 1999-01-13 2002-07-02 Dainippon Pharmaceutical Co., Ltd. Disintegrating tablet in oral cavity and production thereof
US6432442B1 (en) * 1998-02-23 2002-08-13 Mcneil-Ppc, Inc. Chewable product
EP1058538B9 (de) * 1998-03-06 2013-01-02 Aptalis Pharma S.r.l. Schnell zerfallende tablette
US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
WO1999059544A2 (en) * 1998-05-18 1999-11-25 Takeda Chemical Industries, Ltd. Orally disintegrable tablets
WO2000003735A1 (fr) 1998-07-15 2000-01-27 Asahi Kasei Kogyo Kabushiki Kaisha Excipient
CA2525555A1 (en) * 1998-07-28 2000-02-10 Takeda Pharmaceutical Company Limited Rapidly disintegrable solid preparation
KR100764520B1 (ko) * 1998-08-28 2007-10-09 에자이 알앤드디 매니지먼트 가부시키가이샤 고미 등을 경감한 의약조성물
CA2343148C (en) * 1998-09-10 2005-11-15 Nycomed Danmark A/S Quick release pharmaceutical compositions of drug substances
US8231899B2 (en) 1998-09-10 2012-07-31 Nycomed Danmark Aps Quick release pharmaceutical compositions of drug substances
US6743443B1 (en) 1998-10-05 2004-06-01 Eisai Co., Ltd. Tablets immediately disintegrating in the oral cavity
JP2000178204A (ja) * 1998-10-05 2000-06-27 Eisai Co Ltd ホスフォジエステラ―ゼ阻害剤を含有する口腔内速崩壊性錠剤
US20010055613A1 (en) * 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
US6296868B1 (en) * 1998-11-19 2001-10-02 Advanced Technology Pharmaceuticals Corporation Chewable tablets containing mannitol and aspartame
US7163705B2 (en) * 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
CN1186098C (zh) * 1999-02-15 2005-01-26 住友制药株式会社 在口腔中迅速崩解的片剂
WO2000048575A1 (fr) * 1999-02-17 2000-08-24 Kyowa Hakko Kogyo Co., Ltd. Comprimes et procede de production de comprimes
GB9910505D0 (en) 1999-05-06 1999-07-07 Electrosols Ltd A method and apparatus for manufacturing consumable tablets
DE19931708A1 (de) * 1999-07-08 2001-01-18 Bayer Ag Verfahren zur Herstellung schnell zerfallender, fester pharmazeutischer Zubereitungen
US6384020B1 (en) * 1999-07-14 2002-05-07 Shire Laboratories, Inc. Rapid immediate release oral dosage form
US6284270B1 (en) * 1999-08-04 2001-09-04 Drugtech Corporation Means for creating a mass having structural integrity
JP4719899B2 (ja) * 2000-01-07 2011-07-06 大正製薬株式会社 口腔内速崩壊性錠剤
DK1260215T3 (da) 2000-03-01 2009-11-09 Eisai R&D Man Co Ltd Hurtig disintegrerende tablet indeholdende polyvinylalkohol
US20020015730A1 (en) * 2000-03-09 2002-02-07 Torsten Hoffmann Pharmaceutical formulations and method for making
EP1133984B1 (de) 2000-03-17 2005-05-11 Shin-Etsu Chemical Co., Ltd. Feste Zubereitung enthaltend niedersubstituierte Hydroxypropylcellulose und Herstellungsverfahren
CA2403594A1 (en) * 2000-03-27 2002-09-18 Kyowa Hakko Kogyo Co., Ltd. Granules having good taking property
HU229550B1 (en) 2000-06-27 2014-01-28 Hoffmann La Roche Method for preparing compositions
JP3415835B2 (ja) 2000-06-30 2003-06-09 山之内製薬株式会社 口腔内速崩壊錠およびその製造法
US6656492B2 (en) 2000-06-30 2003-12-02 Yamanouchi Pharmaceutical Co., Ltd. Quick disintegrating tablet in buccal cavity and manufacturing method thereof
EP1309315B1 (de) * 2000-08-18 2006-06-14 Pharmacia Corporation Schnell zerfallende orale arzneizubereitung enthaltend valdecoxib
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
RU2273472C2 (ru) * 2000-10-16 2006-04-10 Дайити Фармасьютикал Ко., Лтд. Лекарственный состав, быстро распадающийся в ротовой полости, и способ его изготовления
US6733781B2 (en) * 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
US7799342B2 (en) 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
US6544552B2 (en) 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
US20030022912A1 (en) * 2001-02-08 2003-01-30 Martino Alice C. Rapid-onset medicament for treatment of sexual dysfunction
JP4179784B2 (ja) * 2001-02-15 2008-11-12 田辺三菱製薬株式会社 口腔内速崩壊性錠
JPWO2002069934A1 (ja) * 2001-03-06 2004-07-02 協和醗酵工業株式会社 口腔内速崩壊性製剤
US6706284B2 (en) 2001-03-15 2004-03-16 Yamanouchi Pharmaceutical Co., Ltd. Bitterness-reduced oral pharmaceutical composition
EP1372604A2 (de) * 2001-03-22 2004-01-02 Battelle Memorial Institute Herstellungsverfahren von auflösenden dosierungsformen
KR100457458B1 (ko) * 2001-04-02 2004-11-17 삼아약품 주식회사 속용정 및 그의 제조방법
WO2002100381A1 (en) * 2001-06-07 2002-12-19 Tanabe Seiyaku Co., Ltd. Functional grain-containing preparations quickly disintegrated in the oral cavity
CN1578657A (zh) * 2001-09-25 2005-02-09 兰贝克赛实验室有限公司 制备快速溶解剂型的方法
US20050053678A1 (en) * 2001-10-03 2005-03-10 Gow Robert T. Methods and compositions for betel nut chewing gum
US7037524B2 (en) * 2001-10-03 2006-05-02 Herbalscience, Llc Oral delivery of a botanical
US20050069596A1 (en) * 2001-10-03 2005-03-31 Gow Robert T. Compositions and methods comprising kava and anti-anxiety compounds
US7291352B2 (en) 2001-10-03 2007-11-06 Herbalscience Llc Methods and compositions for oral delivery of Areca and mate' or theobromine
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
WO2003041698A1 (fr) * 2001-11-13 2003-05-22 Kyowa Hakko Kogyo Co., Ltd. Comprimes contenant des acides amines se desintegrant rapidement dans la cavite buccale et procede de fabrication de ces comprimes
AU2002351008B2 (en) * 2001-11-30 2007-07-12 Pfizer Products Inc. Pharmaceutical compositions of 5,8,14-triazatetracyclo[10.3.1.0(2,11).0(4,9)]-hexadeca-2(11)3,5,7,9-pentaene
US7118765B2 (en) 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
JP2003238393A (ja) * 2002-02-15 2003-08-27 Otsuka Pharmaceut Co Ltd 施錠性が改善された錠剤及びその製造方法
CN1638803A (zh) * 2002-03-06 2005-07-13 协和发酵工业株式会社 口腔内速崩解性片剂
US20030215502A1 (en) * 2002-03-20 2003-11-20 Elan Pharma International Limited Fast dissolving dosage forms having reduced friability
US20030215498A1 (en) * 2002-05-17 2003-11-20 Harland Ronald S. Rapidly disintegrating comressed tablets comprising biologically active compounds
JP4605977B2 (ja) * 2002-06-14 2011-01-05 日本ベーリンガーインゲルハイム株式会社 ブロチゾラムを含有する錠剤
US20040001885A1 (en) * 2002-06-27 2004-01-01 Unchalee Kositprapa Rapidly disintegrating antihistamine formulation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
GB0217056D0 (en) * 2002-07-23 2002-08-28 Ass Octel Use
EP1541140A1 (de) * 2002-08-12 2005-06-15 Kyowa Hakko Kogyo Co., Ltd. Eine aminosäure enthaltendes kauprodukt
US20050037025A1 (en) * 2002-10-03 2005-02-17 Gow Robert T. Methods and compositions comprising kava and mate' or theobromine
EP1545521A2 (de) * 2002-10-04 2005-06-29 Pharmacia Corporation Zusammensetzungen und verfahren zur behandlung der sexuellen dysfunktion
UA80991C2 (en) * 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
FR2845914B1 (fr) * 2002-10-18 2005-11-04 Schwarz Pharma Lab Compose antiemetique a desagregation rapide
US20040161459A1 (en) * 2002-12-31 2004-08-19 Ngoc Do Fast-dissolve tablet technology
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
WO2004098571A1 (en) * 2003-04-30 2004-11-18 Zicam, Llc Cold remedy composition comprising zinc salts
US7204986B2 (en) 2003-06-11 2007-04-17 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
CA2540040C (en) * 2003-10-07 2012-09-11 Andrx Pharmaceuticals Llc Rapidly disintegrating formulation
US8349361B2 (en) 2003-10-15 2013-01-08 Fuji Chemical Industry Co., Ltd. Composition for rapid disintegrating tablet in oral cavity
JP3841804B2 (ja) 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
JP4726628B2 (ja) 2003-10-15 2011-07-20 富士化学工業株式会社 口腔内速崩壊性錠剤
EP1535700A1 (de) * 2003-11-25 2005-06-01 Sika Tivoli GmbH Schleifmittelverbundkörper
WO2005065317A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
CA2548915C (en) * 2003-12-31 2012-10-16 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
US7862833B2 (en) * 2003-12-31 2011-01-04 Cima Labs, Inc. Effervescent oral opiate dosage forms and methods of administering opiates
US7670624B2 (en) 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
TWI335227B (en) * 2004-02-25 2011-01-01 Medical & Pharm Ind Tech & Dev Pharmaceutical composition of taste masking and rapidly dissolving drug and method of preparing the same
US20090246288A1 (en) * 2004-02-25 2009-10-01 Pharmaceutical Industry Technology And Development Center Taste-masking oral dosage form and method of preparing the same
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
ATE493973T1 (de) 2004-06-04 2011-01-15 Teva Pharma Irbesartan enthaltende pharmazeutische zusammensetzung
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
ITMI20042356A1 (it) * 2004-12-10 2005-03-10 Acraf Composizione farmaceutica orodisperdibile e procedimento per prepararla
NL1027807C1 (nl) * 2004-12-17 2006-06-20 4Sight Innovation Bv Inrichting voor het verrijken van een drank met additieven, en verpakking voor een dergelijke inrichting.
BRPI0610780A2 (pt) * 2005-04-22 2016-09-06 Teva Pharma formulação farmacéutica em tablete desintegrante, e, métodos para tratar um paciente em necessidade de tratamento com olanzapina, e para produzir a formulação farmacêutica em tablete
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US20090136569A1 (en) * 2005-07-22 2009-05-28 Katsuji Uemura Rapidly disintergrating tablet in oral cavity
US20070020186A1 (en) * 2005-07-22 2007-01-25 Alpex Pharma S.A. Solid dosage formulations of narcotic drugs having improved buccal adsorption
CA2617557A1 (en) 2005-08-04 2007-02-15 Sirtris Pharmaceuticals, Inc. Benzimidazole derivatives as sirtuin modulators
US20110142957A1 (en) * 2005-08-15 2011-06-16 Van Kempen Theo Method of treating parturient placental mammals in order to reduce maternal and/or uterine exhaustion
JP2009514857A (ja) * 2005-11-02 2009-04-09 テイコク ファーマ ユーエスエー インコーポレーテッド 感覚器官的に許容されるイブプロフェン経口投与用製剤、該製剤の製法並びに使用法
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
PE20070698A1 (es) 2005-11-14 2007-08-17 Teijin Pharma Ltd Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol
US8956677B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
US20070116822A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener composition with saponin and compositions sweetened therewith
US8435587B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
US20070116836A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith
US20070116829A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8524304B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US20070134391A1 (en) * 2005-11-23 2007-06-14 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith
US9144251B2 (en) * 2005-11-23 2015-09-29 The Coca-Cola Company High-potency sweetener composition with mineral and compositions sweetened therewith
US8956678B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with preservative and compositions sweetened therewith
US20070116839A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
KR20080071606A (ko) * 2005-11-23 2008-08-04 더 코카콜라 컴파니 시간 특성 및/또는 향미 특성이 개선된 인공 감미료조성물과 이들의 제제 방법 및 용도
US8524303B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
US8377491B2 (en) * 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
US20070116825A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Confection with High-Potency Sweetener
US20070116800A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US20070116831A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Dental Composition with High-Potency Sweetener
US8993027B2 (en) * 2005-11-23 2015-03-31 The Coca-Cola Company Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses
US20070116833A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
MY149082A (en) 2005-12-28 2013-07-15 Meiji Co Ltd Solid milk and method of making the same
JP5100634B2 (ja) * 2006-03-24 2012-12-19 興和株式会社 口腔内速崩壊性錠剤
US8846100B2 (en) * 2006-05-12 2014-09-30 Shire Llc Controlled dose drug delivery system
US20080014228A1 (en) * 2006-07-14 2008-01-17 Olivia Darmuzey Solid form
EP1891946A1 (de) * 2006-08-14 2008-02-27 Santhera Pharmaceuticals (Schweiz) AG Transmukosale Verabreichung von 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinon
US20080085309A1 (en) 2006-09-14 2008-04-10 Astellas Pharma Inc. Rapidly disintegrating tablets in buccal cavity and manufacturing method thereof
US20100034888A1 (en) * 2006-09-15 2010-02-11 Hubert Clemens Pellikaan Granulate containing a pharmaceutically active substance and method for its manufacture
US20080107787A1 (en) * 2006-11-02 2008-05-08 The Coca-Cola Company Anti-Diabetic Composition with High-Potency Sweetener
US9101161B2 (en) * 2006-11-02 2015-08-11 The Coca-Cola Company High-potency sweetener composition with phytoestrogen and compositions sweetened therewith
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
CN101678115B (zh) * 2006-12-26 2012-04-18 株式会社医药处方 多孔干燥基质药用组合物
EP2098250B1 (de) 2006-12-28 2016-09-28 Takeda Pharmaceutical Company Limited Oral zerfallende feste zubereitung
ES2302650B1 (es) 2007-01-11 2009-02-16 Tedec-Meiji Farma, S.A. Composicion de rapida desintegracion en la cavidad bucal.
US20080187628A1 (en) * 2007-02-02 2008-08-07 Champion Melinda L Water-Soluble, Quick-Dissolve Flavor Tablets
US20080260823A1 (en) * 2007-04-20 2008-10-23 Sciele Pharma, Inc. Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
JP4980144B2 (ja) * 2007-06-05 2012-07-18 日機装株式会社 固型化透析用剤の製造方法
JP2009035505A (ja) * 2007-08-01 2009-02-19 Takada Seiyaku Kk レボフロキサシン錠剤
US20090060983A1 (en) * 2007-08-30 2009-03-05 Bunick Frank J Method And Composition For Making An Orally Disintegrating Dosage Form
US20090110716A1 (en) * 2007-10-31 2009-04-30 Frank Bunick Orally disintegrative dosage form
JP4832407B2 (ja) * 2007-11-19 2011-12-07 花王株式会社 コラーゲン含有組成物
CN101917975B (zh) * 2007-12-21 2013-05-08 麦克内尔-Ppc股份有限公司 片剂的制造
JP5547096B2 (ja) * 2008-02-28 2014-07-09 アール．ピー． シェーラー テクノロジーズ エルエルシー 多型を最小化する方法
EP2100595A1 (de) * 2008-03-10 2009-09-16 The Procter and Gamble Company Komprimierte Tabletten
US20100075930A1 (en) * 2008-09-03 2010-03-25 Yoel Ovil Salicylic salt compositions and related method of treatment of cardiac conditions
CA2750216A1 (en) * 2008-12-15 2010-07-08 Fleming And Company, Pharmaceuticals Rapidly dissolving vitamin formulation and methods of using the same
KR101565621B1 (ko) 2009-01-26 2015-11-03 신에쓰 가가꾸 고교 가부시끼가이샤 저치환도 히드록시프로필셀룰로오스 수분산액을 이용한 습식 조립 타정법
EP2405905B1 (de) * 2009-03-09 2016-06-29 SPI Pharma, INC. Hoch verdichtungsfähige und beständige direktkompressionshilfsstoffe und hilfsstoffsysteme
US20110097401A1 (en) * 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
JP2011037767A (ja) * 2009-08-11 2011-02-24 Dainippon Sumitomo Pharma Co Ltd 薬物および噴霧乾燥粒子を含有する口腔内速崩壊錠
US8784781B2 (en) * 2009-09-24 2014-07-22 Mcneil-Ppc, Inc. Manufacture of chewing gum product with radiofrequency
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US8858210B2 (en) 2009-09-24 2014-10-14 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
US20110070286A1 (en) * 2009-09-24 2011-03-24 Andreas Hugerth Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process
JP5309262B2 (ja) 2009-12-02 2013-10-09 アプタリス ファーマ リミテッド フェキソフェナジン・マイクロカプセル及びそれを含む組成物
TW201127375A (en) * 2010-01-08 2011-08-16 Eurand Inc Taste masked topiramate composition and an orally disintegrating tablet comprising the same
JP5513936B2 (ja) * 2010-03-10 2014-06-04 全星薬品工業株式会社 口腔内崩壊製剤
JP2010174028A (ja) * 2010-03-18 2010-08-12 Rohto Pharmaceut Co Ltd 苦味を有する薬物を含有する口中溶解型又は咀嚼型固形内服医薬組成物
KR101232088B1 (ko) * 2010-05-11 2013-02-08 박대철 용해성이 향상된 태블릿 제조방법
MX2013002430A (es) 2010-09-01 2013-07-22 Arena Pharm Inc Formas de dosis de disolucion de rápida de agonistas de 5-ht2c.
CA2819663C (en) 2010-12-02 2019-12-24 Aptalis Pharmatech, Inc. Rapidly dispersing granules, orally disintegrating tablets and methods
AU2011350396A1 (en) 2010-12-27 2013-07-11 Takeda Pharmaceutical Company Limited Orally disintegrating tablet
MX2014007933A (es) 2011-12-26 2014-07-30 Novartis Ag Comprimidos y agentes recubiertos en seco.
KR20130076015A (ko) 2011-12-28 2013-07-08 주식회사 삼양바이오팜 높은 경도를 갖는 속붕정 및 이의 제조 방법
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
JP2013028647A (ja) * 2012-11-06 2013-02-07 Rohto Pharmaceutical Co Ltd 苦味を有する薬物を含有する口中溶解型又は咀嚼型固形内服医薬組成物
FR2999432B1 (fr) 2012-12-17 2014-12-12 Ethypharm Sa Comprimes orodispersibles obtenus par compression moulage
US20150098978A1 (en) * 2013-10-03 2015-04-09 Altria Client Services Inc. Dissolvable-chewable tablet
KR20160108828A (ko) 2013-11-11 2016-09-20 임팩스 라보라토리즈, 인코포레이티드 신속하게 붕괴되는 제형 및 사용 방법
ES2750323T3 (es) 2014-01-10 2020-03-25 Johnson & Johnson Consumer Inc Método para la fabricación de un comprimido mediante radiofrecuencia y partículas recubiertas con pérdida
US9925138B2 (en) 2015-01-20 2018-03-27 Handa Pharmaceuticals, Llc Stable solid fingolimod dosage forms
WO2016155786A1 (en) 2015-03-31 2016-10-06 Laboratorios Bagó S.A. Enteric-coated pellets containing a proton pump inhibitor
JP6552088B2 (ja) * 2015-04-21 2019-07-31 ライオン株式会社 造粒顆粒およびその製造方法と、錠剤およびその製造方法
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
CN113876725A (zh) * 2020-10-12 2022-01-04 北京中科利华医药研究院有限公司 一种维生素b6片剂及其制备方法
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
WO2022103639A1 (en) * 2020-11-16 2022-05-19 Orcosa Inc. Methods of treating autoimmune or inflammatory conditions with cannabidiol or its derivatives/analogs

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2926121A (en) * 1957-03-20 1960-02-23 American Home Prod Therapeutic candy-like product and its preparation
GB1134097A (en) * 1965-11-25 1968-11-20 Internat Chemical Company Ltd Improvements in antacid tablets
DE2556561C2 (de) * 1975-12-16 1983-04-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Herstellung von porösen Tabletten
JPS5824410A (ja) * 1981-08-06 1983-02-14 Toppan Printing Co Ltd チユ−ブの製造方法
GB2111423B (en) * 1981-12-02 1985-06-26 Wyeth John & Brother Ltd Making quick-dissolving pills
US4414198A (en) * 1982-04-23 1983-11-08 Joseph Michaelson Rapidly disintegrable tablet composition and method
AU582167B2 (en) * 1984-06-28 1989-03-16 Procter & Gamble Company, The Antacid composition
US4684534A (en) * 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
ES2060737T3 (es) * 1988-02-25 1994-12-01 Yamanouchi Europ Bv Procedimiento de preparacion de un granulado farmaceutico.
US5082667A (en) * 1988-06-07 1992-01-21 Abbott Laboratories Solid pharmaceutical dosage in tablet triturate form and method of producing same
US5073374A (en) * 1988-11-30 1991-12-17 Schering Corporation Fast dissolving buccal tablet
US5112616A (en) * 1988-11-30 1992-05-12 Schering Corporation Fast dissolving buccal tablet
US4946684A (en) * 1989-06-20 1990-08-07 American Home Products Corporation Fast dissolving dosage forms
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
JP2807346B2 (ja) * 1991-12-24 1998-10-08 山之内製薬株式会社 口腔内崩壊製剤及びその製造法
TW272942B (de) * 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
DE69331839D1 (de) 2002-05-29
CA2088334C (en) 2004-06-15
ATE216577T1 (de) 2002-05-15
JPH05271054A (ja) 1993-10-19
US5501861A (en) 1996-03-26
KR100258223B1 (ko) 2000-08-01
KR930016092A (ko) 1993-08-26
EP0553777A2 (de) 1993-08-04
JP2000264836A (ja) 2000-09-26
US5720974A (en) 1998-02-24
EP0553777B1 (de) 2002-04-24
JP3069458B2 (ja) 2000-07-24
EP0553777A3 (en) 1994-12-14
JP4336021B2 (ja) 2009-09-30
TW249756B (de) 1995-06-21
CA2088334A1 (en) 1993-07-30

Similar Documents

Publication Publication Date Title
DE69331839T2 (de) Schnellösliche Tablette und ihre Herstellung
ATA195588A (de) Epipodophyllotoxinglucosid-4'-phosphat-derivate deren herstellung, sowie pharmazeutische zusammensetzungen hierzu
CA2046943A1 (en) Process for producing an agent with the active substance flupirtine to combat muscular tension
DE3766200D1 (de) L-dopa enthaltendes arzneimittel.
HUT47369A (en) Acaricide and fungicide compositions containing substituted 1,4-naphtoquinones and process for producing the active components
PT615754E (pt) Formas solidas de administracao oral de libertacao controlada flupertina
CA2140545A1 (en) Use of first runnings coconut fatty acid as insect-repellent
AU4585493A (en) Percutaneously administrable base composition and drug composition prepared therefrom
EP0418892A3 (en) Bathing preparation
HUT38219A (en) Herbicidal compositions comprising delta above 2-1,2,4-triazoline-5-on-derivatives as active substance and process for producing the active substance
WO1997048382A3 (en) Multiple-unit type prolonged action drug preparation
GR3020828T3 (en) Sustained release suppositories and a process for preparation
CA2047027A1 (en) Tablet and granulate containing mesna as active substance
EP0286601A3 (de) Pulveriges Deodorantmittel für Schuhe, besonders für Sportschuhe
HUT48096A (en) Insecticides comprising 2-imino-1,3-dithiethane derivatives as active ingredient and process for producing the active ingredients
HUT49850A (en) Herbicidal compositions comprising pyran derivatives and process for producing the active ingredients
HUT46838A (en) Pesticide compositions containing 2,5-bis-pyridyl-1,3,4-thiadiazol derivatives as active components and process for producing the active components
EP0303513A3 (de) Traggestell
JPS5495737A (en) Stabilized composition containing carpronium chloride
FR2424701A1 (fr) Composition fongicide a base de triazole et procede de traitement fongicide de plantes cultivees
JPS53147003A (en) Preparation of beta,gamma-unsaturated compounds
IE782540L (en) Tablets containing¹1,3-bis(2-carboxychromon-5-yloxy)-2-hydroxypropane
JPS5714587A (en) Stabilizing method of ascorbic acid
HUT39458A (en) Acaricide, insecticide and fungicide compositions containing n-alkyl/ene/-n-/o,o-disubstituted-thiophosphoryl/-n-comma above,n-comma above-disubstituted-glycin-amide as active agent and process for producing the active agent
USD240442S (en)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP

R071 Expiry of right

Ref document number: 553777

Country of ref document: EP