DE69334197D1 - Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und Diagnostik - Google Patents
Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und DiagnostikInfo
- Publication number
- DE69334197D1 DE69334197D1 DE69334197T DE69334197T DE69334197D1 DE 69334197 D1 DE69334197 D1 DE 69334197D1 DE 69334197 T DE69334197 T DE 69334197T DE 69334197 T DE69334197 T DE 69334197T DE 69334197 D1 DE69334197 D1 DE 69334197D1
- Authority
- DE
- Germany
- Prior art keywords
- vaccines
- diagnostics
- useful
- helicobacter pylori
- pylori cytotoxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101710112752 Cytotoxin Proteins 0.000 title 1
- 241000590002 Helicobacter pylori Species 0.000 title 1
- 231100000599 cytotoxic agent Toxicity 0.000 title 1
- 239000002619 cytotoxin Substances 0.000 title 1
- 229940037467 helicobacter pylori Drugs 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITFI920052 | 1992-03-02 | ||
ITFI920052A IT1262895B (it) | 1992-03-02 | 1992-03-02 | Proteina estratta da ceppi citotossici di helicobacter pylori, gene che la esprime, uso della proteina come vaccino o diagnostico. |
EPPCT/EP93/00158 | 1993-01-25 | ||
WOPCT/EP93/00158 | 1993-01-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69334197D1 true DE69334197D1 (de) | 2008-02-14 |
DE69334197T2 DE69334197T2 (de) | 2008-12-11 |
Family
ID=26069992
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69334197T Expired - Lifetime DE69334197T2 (de) | 1992-03-02 | 1993-03-02 | Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und Diagnostik |
DE69333110T Expired - Lifetime DE69333110T2 (de) | 1992-03-02 | 1993-03-02 | Mit dem cytotoxin von helicobacter pylori assoziiertes, immunodominantes antigen verwendbar in impfstoffen und zur diagnose |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69333110T Expired - Lifetime DE69333110T2 (de) | 1992-03-02 | 1993-03-02 | Mit dem cytotoxin von helicobacter pylori assoziiertes, immunodominantes antigen verwendbar in impfstoffen und zur diagnose |
Country Status (7)
Country | Link |
---|---|
US (3) | US6077706A (de) |
EP (1) | EP0967279B1 (de) |
JP (4) | JP3368902B2 (de) |
AU (1) | AU3630093A (de) |
CA (2) | CA2383007A1 (de) |
DE (2) | DE69334197T2 (de) |
WO (1) | WO1993018150A1 (de) |
Families Citing this family (92)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5866375A (en) * | 1991-10-31 | 1999-02-02 | Chiron S.P.A. | Method for the culture of microorganisms of the genera helicobacter, campylobacter and arcobacter employing culture media comprising cyclodextrins |
EP0629132B1 (de) * | 1992-02-26 | 2004-08-11 | Vanderbilt University | Gereinigtes vakuolisierendes toxin aus helicobacter pylori und methoden zu dessen verwendung |
US5721349A (en) * | 1992-02-26 | 1998-02-24 | Vanderbilt University | Vacuolating toxin-deficient H. pylori |
US5928865A (en) * | 1992-03-02 | 1999-07-27 | Chiron S.P.A. | Compositions comprising isolated Helicobacter pylori CagI polynucleotides and method of preparation thereof |
IT1262896B (it) * | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
MX9301706A (es) * | 1992-04-13 | 1994-05-31 | Oravax Inc | Composicion de vacuna para el tratamiento de la infeccion por helicobacter. |
US5403924A (en) * | 1992-10-13 | 1995-04-04 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration |
US5733740A (en) * | 1992-10-13 | 1998-03-31 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma |
US6290962B1 (en) * | 1992-11-03 | 2001-09-18 | Oravax, Inc. | Urease-based vaccine and treatment for helicobacter infection |
US5972336A (en) * | 1992-11-03 | 1999-10-26 | Oravax Merieux Co. | Urease-based vaccine against helicobacter infection |
US6258359B1 (en) | 1993-05-19 | 2001-07-10 | Institut Pasteur | Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides |
WO1995014093A1 (en) * | 1993-05-19 | 1995-05-26 | Institut Pasteur | Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions and nucleic acid sequences encoding said polypeptides |
GB9313279D0 (en) * | 1993-06-28 | 1993-08-11 | Medical Res Council | Protection against infection with helicobacter pylori |
US6406703B1 (en) | 1993-07-27 | 2002-06-18 | Csl Limited | Treatment of H. pylori associated gastroduodenal disease |
WO1995003824A1 (en) * | 1993-07-27 | 1995-02-09 | Csl Limited | Treatment of h. pylori associated gastroduodenal disease |
US5750119A (en) * | 1994-01-13 | 1998-05-12 | Mount Sinai School Of Medicine Of The City University Of New York | Immunotherapeutic stress protein-peptide complexes against cancer |
US5997873A (en) * | 1994-01-13 | 1999-12-07 | Mount Sinai School Of Medicine Of The City University Of New York | Method of preparation of heat shock protein 70-peptide complexes |
US5961979A (en) * | 1994-03-16 | 1999-10-05 | Mount Sinai School Of Medicine Of The City University Of New York | Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens |
GB2290710B (en) * | 1994-06-29 | 1998-03-25 | Reckitt & Colmann Prod Ltd | Protease from helicobacter pylori for use in vaccines/therapeutic compositions |
ATE229978T1 (de) * | 1994-07-01 | 2003-01-15 | Chiron Corp | Helicobacter proteine und impstoffe |
GB9505438D0 (en) * | 1995-03-17 | 1995-05-03 | Sod Conseils Rech Applic | Antisense oligonucleotides |
WO1997003359A1 (en) * | 1995-07-07 | 1997-01-30 | Oravax, Inc. | Helicobacter clpb |
US5935576A (en) | 1995-09-13 | 1999-08-10 | Fordham University | Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens |
US5837251A (en) * | 1995-09-13 | 1998-11-17 | Fordham University | Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases |
US5985270A (en) * | 1995-09-13 | 1999-11-16 | Fordham University | Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes |
WO1997013784A1 (fr) * | 1995-10-09 | 1997-04-17 | Pasteur Merieux Serums Et Vaccins | Recepteur lactoferrine d'helicobacter |
AU1463097A (en) * | 1996-01-04 | 1997-08-01 | Rican Limited | Helicobacter pylori bacterioferritin |
JPH1033179A (ja) * | 1996-07-24 | 1998-02-10 | Fuso Yakuhin Kogyo Kk | 感染症診断用プローブ |
WO1998012562A1 (en) * | 1996-09-20 | 1998-03-26 | Cortecs International Limited | Adhesins from heliobacter pylori and their diagnostic and therapeutic uses |
PT946874E (pt) * | 1996-12-19 | 2002-10-31 | Chiron Corp | Diagnostico de helicobacter pylori |
US5830464A (en) * | 1997-02-07 | 1998-11-03 | Fordham University | Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy |
US6017540A (en) | 1997-02-07 | 2000-01-25 | Fordham University | Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes |
AU751433B2 (en) * | 1997-04-30 | 2002-08-15 | Merieux Oravax | Anti-(helicobacter) vaccine composition for use by the subdiaphragmatic systemic route, and combined mucosal/parenteral immunization method |
FR2748477B1 (fr) * | 1997-07-01 | 2001-07-13 | Pasteur Merieux Serums Vacc | Nouvelle proteine membranaire d'helicobacter pylori |
US6914131B1 (en) | 1998-10-09 | 2005-07-05 | Chiron S.R.L. | Neisserial antigens |
EP1042480A1 (de) * | 1997-12-31 | 2000-10-11 | Stressgen Biotechnologies Corporation | Streptokokken-hitzeschock-proteine, mitglieder der hsp60-familie |
US6585975B1 (en) * | 1998-04-30 | 2003-07-01 | Acambis, Inc. | Use of Salmonella vectors for vaccination against helicobacter infection |
JP4346821B2 (ja) * | 1998-04-30 | 2009-10-21 | カイロン ソチエタ ア レスポンサビリタ リミタータ | H.Pyloriによる感染に対する免疫化および処置 |
US6838553B1 (en) * | 1999-10-05 | 2005-01-04 | Academia Sinica | Peptide repeat immunogens |
GB9924060D0 (en) * | 1999-10-11 | 1999-12-15 | Chiron Spa | VIP54 protein |
EP2975127A1 (de) | 1999-10-29 | 2016-01-20 | GlaxoSmithKline Biologicals SA | Neisseria antigenpeptide |
EP2275129A3 (de) | 2000-01-17 | 2013-11-06 | Novartis Vaccines and Diagnostics S.r.l. | Ergänzter Außenmembranvesikel-Impfstoff gegen Meningokokken |
AU2001266694C1 (en) | 2000-06-02 | 2005-09-01 | University Of Connecticut Health Center | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy |
US20020107368A1 (en) * | 2000-12-07 | 2002-08-08 | Jing-Hui Tian | Helicobacter proteins, gene sequences and uses thereof |
EP2305299B1 (de) | 2001-05-31 | 2017-03-01 | GlaxoSmithKline Biologicals SA | Chimäre alphavirus-replikonpartikel |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
JP4384489B2 (ja) | 2001-08-20 | 2009-12-16 | ユニバーシティー オブ コネティカット ヘルス センター | 癌及び感染性疾患の治療に有用な熱ショックタンパク質又はα−2−マクログロブリンを含む組成物の調製方法 |
WO2003070909A2 (en) | 2002-02-20 | 2003-08-28 | Chiron Corporation | Microparticles with adsorbed polypeptide-containing molecules |
EP1547607A4 (de) * | 2002-08-02 | 2008-11-26 | Dainippon Sumitomo Pharma Co | Herstellung einer komponente des bakterienzellwand-skeletts |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
BR0315767A (pt) | 2002-11-01 | 2005-09-06 | Glaxosmithkline Biolog Sa | Composição imunogência, método para fabricar uma vacina, kit, vacina, recipiente com uma superfìcie interna repelente à água, e, método para preservar uma composição que compreende ipv e um agente estabilizador |
PT2279746E (pt) | 2002-11-15 | 2013-12-09 | Novartis Vaccines & Diagnostic | Proteínas de superfície de neisseria meningitidis |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
WO2004060396A2 (en) | 2002-12-27 | 2004-07-22 | Chiron Corporation | Immunogenic compositions containing phospholpid |
US7893096B2 (en) | 2003-03-28 | 2011-02-22 | Novartis Vaccines And Diagnostics, Inc. | Use of small molecule compounds for immunopotentiation |
GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
ES2596553T3 (es) | 2003-06-02 | 2017-01-10 | Glaxosmithkline Biologicals Sa | Composiciones inmunogénicas a base de micropartículas que comprenden toxoide adsorbido y un antígeno que contiene un polisacárido |
EP1654283B1 (de) | 2003-08-13 | 2011-07-13 | Novartis Vaccines and Diagnostics, Inc. | Verbessertes verfahren zur reinigung von tfpi und tfpi-analogen |
WO2005080414A1 (en) | 2004-02-19 | 2005-09-01 | Ramot At Tel-Aviv University Ltd | Peptide mimotopes of mycobacterial mannosylated lipoglycans and uses thereof |
WO2005102369A1 (ja) * | 2004-04-22 | 2005-11-03 | Dainippon Sumitomo Pharma Co., Ltd. | 細菌細胞壁骨格成分を含有する製剤 |
CA2571421A1 (en) | 2004-06-24 | 2006-01-05 | Nicholas Valiante | Compounds for immunopotentiation |
EP1768662A2 (de) | 2004-06-24 | 2007-04-04 | Novartis Vaccines and Diagnostics, Inc. | Immunstimulatoren kleiner moleküle und assays für deren nachweis |
DE602005017391D1 (de) | 2004-06-24 | 2009-12-10 | Yissum Res Dev Co | Verwendung von peptid-mimotopen von mannosylierten lipoglycanen aus mycobacterien zur behandlung von entzündungen |
JP2008508320A (ja) | 2004-07-29 | 2008-03-21 | カイロン コーポレイション | Streptococcusagalactiaeのようなグラム陽性細菌に対する免疫原性組成物 |
EP1838340B1 (de) * | 2004-12-22 | 2018-04-04 | Cleveland Clinic Foundation | Mit flagellin verwandte polypeptide und ihre verwendungen |
WO2007047749A1 (en) | 2005-10-18 | 2007-04-26 | Novartis Vaccines And Diagnostics Inc. | Mucosal and systemic immunizations with alphavirus replicon particles |
WO2007081447A2 (en) | 2005-11-22 | 2007-07-19 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and sapovirus antigens |
CA2646539A1 (en) | 2006-03-23 | 2007-09-27 | Novartis Ag | Imidazoquinoxaline compounds as immunomodulators |
KR100846494B1 (ko) * | 2006-09-26 | 2008-07-17 | 삼성전자주식회사 | 헬리코박터 파일로리의 표적 서열을 증폭하기 위한프라이머 세트, 상기 프라이머 세트를 이용하여 헬리코박터파일로리를 검출하는 방법 및 상기 프라이머 세트를포함하는 헬리코박터 파일로리를 검출하는 키트 |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
ES2561483T3 (es) | 2007-09-12 | 2016-02-26 | Glaxosmithkline Biologicals Sa | Antígenos mutantes de GAS57 y anticuerpos de GAS57 |
KR101773114B1 (ko) | 2007-12-21 | 2017-08-30 | 노파르티스 아게 | 스트렙토라이신 o의 돌연변이 형태 |
JP5577337B2 (ja) | 2008-08-01 | 2014-08-20 | クリーブランド バイオラブス, インコーポレイテッド | 再灌流傷害を治療するための方法 |
EP2331127A2 (de) | 2008-09-18 | 2011-06-15 | Novartis AG | Vakzine-adjuvans-kombinationen |
US8465751B2 (en) | 2009-01-12 | 2013-06-18 | Novartis Ag | Cna—B domain antigens in vaccines against gram positive bacteria |
AU2010288239B2 (en) | 2009-08-27 | 2014-01-16 | Novartis Ag | Adjuvant comprising aluminium, oligonucleotide and polycation |
MX2012002723A (es) | 2009-09-02 | 2012-04-11 | Novartis Ag | Composiciones inmunogenicas que incluyen moduladores de la actividad de receptores tipo toll. |
KR20130121699A (ko) | 2010-05-28 | 2013-11-06 | 테트리스 온라인, 인코포레이티드 | 상호작용 혼성 비동기 컴퓨터 게임 기반구조 |
ES2458355T3 (es) | 2010-09-01 | 2014-05-05 | Novartis Ag | Adsorción de inmunopotenciadores sobre sales metálicas insolubles |
WO2012082914A1 (en) | 2010-12-14 | 2012-06-21 | Novartis Ag | Flow cytometry analysis of materials adsorbed to metal salts |
AU2012205681B2 (en) | 2011-01-10 | 2016-07-28 | Cleveland Biolabs, Inc. | Use of toll-like receptor agonist for treating cancer |
RU2013144207A (ru) | 2011-03-02 | 2015-04-10 | Новартис Аг | Комбинированные вакцины с пониженными дозами антигена и/или адъюванта |
WO2013131983A1 (en) | 2012-03-07 | 2013-09-12 | Novartis Ag | Adjuvanted formulations of streptococcus pneumoniae antigens |
DK2822947T3 (en) | 2012-03-07 | 2016-09-19 | Glaxosmithkline Biologicals Sa | ARGINAL SALTS OF A TLR-7 AGONIST |
RU2014140521A (ru) | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
EP2877852B1 (de) * | 2012-07-23 | 2022-05-25 | Hermouet, Sylvie | Protein-mikroarray zur charakterisierung der spezifität der monoklonalen immunoglobuline von mgus- oder myelom-patienten |
AU2015296555B2 (en) | 2014-07-30 | 2020-05-21 | Genome Protection, Inc. | Flagellin compositons and uses |
US10183056B2 (en) | 2014-10-16 | 2019-01-22 | Cleveland Biolabs, Inc. | Methods and compositions for the treatment of radiation-related disorders |
SE541618C2 (en) * | 2017-02-24 | 2019-11-12 | Biotome Pty Ltd | Novel peptides and their use in diagnosis |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0274482B2 (de) | 1986-03-28 | 2003-03-12 | The Board Of Trustees Of The University Of Illinois | Mit mehrfacharzneimittelresistenz assoziierte,isolierte dna-sequenzen in menschlichen zellen |
US5554372A (en) | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
US5459041A (en) * | 1988-02-18 | 1995-10-17 | Enteric Research Laboratories, Inc. | Campylobacter pylori antigens and uses thereof for detection of Campylobacter pylori infection |
US4882271A (en) * | 1988-03-10 | 1989-11-21 | Baylor College Of Medicine | Process for preparation of high molecular weight cell-associated protein of campylobacter pylori and use for serological detection of campylobacter pylori infection |
FR2637612B1 (fr) * | 1988-10-06 | 1993-09-10 | Pasteur Institut | Sequences de nucleotides codant pour une proteine a activite ureasique |
JP3436756B2 (ja) | 1988-12-19 | 2003-08-18 | アメリカン・サイアナミド・カンパニー | 髄膜炎菌のクラスiの外膜タンパク質のワクチン |
GB8928625D0 (en) * | 1989-12-19 | 1990-02-21 | 3I Res Expl Ltd | H.pylori dna probes |
US5292658A (en) | 1989-12-29 | 1994-03-08 | University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center | Cloning and expressions of Renilla luciferase |
ATE241704T1 (de) | 1991-08-27 | 2003-06-15 | Hoffmann La Roche | Primers und sondern zum nachweis von hepatitis c |
US5354854A (en) | 1991-11-07 | 1994-10-11 | The Curators Of The University Of Missouri | Expression system for use in plants to suppress foreign expression and method |
US5721349A (en) * | 1992-02-26 | 1998-02-24 | Vanderbilt University | Vacuolating toxin-deficient H. pylori |
IT1262895B (it) | 1992-03-02 | 1996-07-22 | Proteina estratta da ceppi citotossici di helicobacter pylori, gene che la esprime, uso della proteina come vaccino o diagnostico. | |
US5403924A (en) * | 1992-10-13 | 1995-04-04 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration |
US5733740A (en) | 1992-10-13 | 1998-03-31 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma |
US6019982A (en) * | 1994-08-26 | 2000-02-01 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
US6902903B1 (en) | 1996-12-19 | 2005-06-07 | Chiron Corporation | Helicobacter pylori diagnostics |
CA2408328C (en) | 2000-05-10 | 2012-04-17 | Aventis Pasteur Limited | Immunogenic polypeptides encoded by mage minigenes and uses thereof |
-
1993
- 1993-03-02 EP EP99202698A patent/EP0967279B1/de not_active Expired - Lifetime
- 1993-03-02 CA CA002383007A patent/CA2383007A1/en active Pending
- 1993-03-02 AU AU36300/93A patent/AU3630093A/en not_active Abandoned
- 1993-03-02 DE DE69334197T patent/DE69334197T2/de not_active Expired - Lifetime
- 1993-03-02 JP JP51530993A patent/JP3368902B2/ja not_active Expired - Lifetime
- 1993-03-02 WO PCT/EP1993/000472 patent/WO1993018150A1/en active IP Right Grant
- 1993-03-02 CA CA002131729A patent/CA2131729C/en not_active Expired - Lifetime
- 1993-03-02 DE DE69333110T patent/DE69333110T2/de not_active Expired - Lifetime
-
1995
- 1995-06-06 US US08/470,260 patent/US6077706A/en not_active Expired - Lifetime
-
2000
- 2000-04-26 JP JP2000126695A patent/JP3408494B2/ja not_active Expired - Lifetime
- 2000-04-26 JP JP2000126696A patent/JP2000333686A/ja active Pending
-
2001
- 2001-08-02 US US09/921,157 patent/US20040048353A1/en not_active Abandoned
-
2003
- 2003-07-08 US US10/615,668 patent/US7700755B2/en not_active Expired - Fee Related
-
2005
- 2005-09-09 JP JP2005263068A patent/JP2006055168A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2006055168A (ja) | 2006-03-02 |
EP0967279A1 (de) | 1999-12-29 |
DE69333110T2 (de) | 2004-05-06 |
CA2131729A1 (en) | 1993-09-16 |
EP0967279B1 (de) | 2008-01-02 |
JP3368902B2 (ja) | 2003-01-20 |
JP2000350591A (ja) | 2000-12-19 |
CA2131729C (en) | 2008-02-12 |
CA2383007A1 (en) | 1993-09-16 |
WO1993018150A1 (en) | 1993-09-16 |
DE69333110D1 (de) | 2003-08-28 |
JP2000333686A (ja) | 2000-12-05 |
AU3630093A (en) | 1993-10-05 |
US20040048353A1 (en) | 2004-03-11 |
DE69334197T2 (de) | 2008-12-11 |
US7700755B2 (en) | 2010-04-20 |
US6077706A (en) | 2000-06-20 |
US20050276819A1 (en) | 2005-12-15 |
JPH07504565A (ja) | 1995-05-25 |
JP3408494B2 (ja) | 2003-05-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69334197D1 (de) | Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und Diagnostik | |
DE69128981D1 (de) | Geheimübertragungsverfahren und Geheimübertragungseinrichtung | |
DE69315950T2 (de) | Aufzeichnungsgerät und Aufzeichnungsverfahren | |
NO975490L (no) | Heliobacter pylori antigener og vaksinesammensetninger | |
DE69222259T2 (de) | Bilderzeugungsgerät und -verfahren | |
KR890016831A (ko) | 화상확대방법 및 장치 | |
DE68928726T2 (de) | Bilderausrichtungsverfahren und -gerät | |
DE69034055D1 (de) | Bilderzeugungsgerät und Modulationsverfahren | |
DE69124571D1 (de) | Emulgierverfahren und -vorrichtung | |
NO894442D0 (no) | Anordning og fremgangsmaate for tetting av eske-emner. | |
DE69325151D1 (de) | Datenaufnahmeverfahren und Datenaufnahmegerät | |
DE68913903D1 (de) | Übertragungsvorrichtung und Bilderzeugungsgerät in einem. | |
DE68926386D1 (de) | Bildkodiervorrichtung und Bildkodierverfahren | |
DE69123660D1 (de) | Datenkompressionsmethode und Gerät | |
DE69029534D1 (de) | Aufzeichnungseinrichtung und Aufzeichnungsmethode | |
DE69125315D1 (de) | Kodierverfahren und Kodiervorrichtung | |
DE69407483T2 (de) | Aufzeichnungsgerät und Aufzeichnungsverfahren | |
DE69101974T2 (de) | Gerät zum Mischen und Granulieren. | |
DE68904814D1 (de) | Bilderzeugungsvorrichtung und bilderzeugungsverfahren. | |
DE69425770D1 (de) | Direktes Aufzeichnungsverfahren und direkte Aufzeichnungsvorrichtung | |
DE69315404T2 (de) | Aufzeichnungsgerät und Aufzeichnungsverfahren | |
DE69419065T2 (de) | Bildtransformationsvorrichtung und -verfahren | |
DE69019922T2 (de) | Thermokopf und Thermoübertragungsvorrichtung. | |
DE69001135T2 (de) | Loetverfahren und loetgeraet. | |
DE69124565T2 (de) | Gassyntheseverfahren und -vorrichtung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |