DE69401938D1 - Vorrichtung bei elektroübertragungslieferung von wirkstoff - Google Patents

Vorrichtung bei elektroübertragungslieferung von wirkstoff

Info

Publication number
DE69401938D1
DE69401938D1 DE69401938T DE69401938T DE69401938D1 DE 69401938 D1 DE69401938 D1 DE 69401938D1 DE 69401938 T DE69401938 T DE 69401938T DE 69401938 T DE69401938 T DE 69401938T DE 69401938 D1 DE69401938 D1 DE 69401938D1
Authority
DE
Germany
Prior art keywords
components
active substance
disposable
assembly
electric transfer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69401938T
Other languages
English (en)
Other versions
DE69401938T2 (de
Inventor
Gary Lattin
Dale Dickson
Michael Grace
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DE69401938D1 publication Critical patent/DE69401938D1/de
Publication of DE69401938T2 publication Critical patent/DE69401938T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
DE69401938T 1993-05-28 1994-05-27 Vorrichtung bei elektroübertragungslieferung von wirkstoff Expired - Lifetime DE69401938T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/069,270 US5445609A (en) 1993-05-28 1993-05-28 Electrotransport agent delivery device having a disposable component and a removable liner
PCT/US1994/006070 WO1994027671A1 (en) 1993-05-28 1994-05-27 Electrotransport agent delivery device

Publications (2)

Publication Number Publication Date
DE69401938D1 true DE69401938D1 (de) 1997-04-10
DE69401938T2 DE69401938T2 (de) 1997-10-09

Family

ID=22087843

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69401938T Expired - Lifetime DE69401938T2 (de) 1993-05-28 1994-05-27 Vorrichtung bei elektroübertragungslieferung von wirkstoff

Country Status (7)

Country Link
US (1) US5445609A (de)
EP (1) EP0700309B1 (de)
JP (1) JP3504269B2 (de)
AT (1) ATE149363T1 (de)
AU (1) AU7048494A (de)
DE (1) DE69401938T2 (de)
WO (1) WO1994027671A1 (de)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5749847A (en) * 1988-01-21 1998-05-12 Massachusetts Institute Of Technology Delivery of nucleotides into organisms by electroporation
FR2709670B1 (fr) * 1993-09-10 1995-10-20 Asulab Sa Dispositif en trois modules pour l'administration transdermique de médicaments par électrophorèse ou iontophorèse.
EP0744971A1 (de) * 1994-02-15 1996-12-04 Biosearch Italia S.p.A. Zentrale venenkatheter mit aufgebrachten ramoplanin - antibiotikum zur verneidung von katheterbezogenen infektionen
GB2317343B (en) * 1995-05-15 1999-06-23 Alza Corp Electrotransport device having reusable controller
US5983131A (en) * 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
US8825152B2 (en) 1996-01-08 2014-09-02 Impulse Dynamics, N.V. Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
US9289618B1 (en) 1996-01-08 2016-03-22 Impulse Dynamics Nv Electrical muscle controller
US8321013B2 (en) 1996-01-08 2012-11-27 Impulse Dynamics, N.V. Electrical muscle controller and pacing with hemodynamic enhancement
US7167748B2 (en) 1996-01-08 2007-01-23 Impulse Dynamics Nv Electrical muscle controller
JP4175662B2 (ja) 1996-01-08 2008-11-05 インパルス ダイナミクス エヌ．ヴイ． 電気的筋肉制御装置
US9713723B2 (en) 1996-01-11 2017-07-25 Impulse Dynamics Nv Signal delivery through the right ventricular septum
USD384745S (en) * 1996-01-23 1997-10-07 Alza Corporation Electrotransport drug delivery system
WO1997048444A1 (en) * 1996-06-19 1997-12-24 Becton Dickinson And Company Iontophoretic delivery of cell adhesion inhibitors
US5857993A (en) * 1996-07-12 1999-01-12 Empi, Inc. Process of making an iontophoresis electrode
US5941843A (en) * 1996-07-12 1999-08-24 Empi, Inc. Iontophoresis electrode
US5871461A (en) * 1996-07-12 1999-02-16 Empi, Inc. Method of making an iontophoresis electrode
US5911223A (en) * 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US7908003B1 (en) 1996-08-19 2011-03-15 Mr3 Medical Llc System and method for treating ischemia by improving cardiac efficiency
US7840264B1 (en) 1996-08-19 2010-11-23 Mr3 Medical, Llc System and method for breaking reentry circuits by cooling cardiac tissue
US5797867A (en) * 1996-09-27 1998-08-25 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
US5738647A (en) * 1996-09-27 1998-04-14 Becton Dickinson And Company User activated iontophoretic device and method for activating same
US5947920A (en) * 1997-03-20 1999-09-07 Dermion, Inc. Self-contained hydrating system and iontophoresis bioelectrode
US6085115A (en) * 1997-05-22 2000-07-04 Massachusetts Institite Of Technology Biopotential measurement including electroporation of tissue surface
ATE353689T1 (de) 1997-07-16 2007-03-15 Metacure Nv Einrichtung zur steuerung eines glatten muskels
US6949081B1 (en) * 1998-08-26 2005-09-27 Non-Invasive Technology, Inc. Sensing and interactive drug delivery
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6708060B1 (en) 1998-11-09 2004-03-16 Transpharma Ltd. Handheld apparatus and method for transdermal drug delivery and analyte extraction
US6611706B2 (en) 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
US6597946B2 (en) 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
US8700161B2 (en) 1999-03-05 2014-04-15 Metacure Limited Blood glucose level control
US8666495B2 (en) 1999-03-05 2014-03-04 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US7171263B2 (en) * 1999-06-04 2007-01-30 Impulse Dynamics Nv Drug delivery device
US7190997B1 (en) * 1999-06-04 2007-03-13 Impulse Dynamics Nv Drug delivery device
US7092753B2 (en) * 1999-06-04 2006-08-15 Impulse Dynamics Nv Drug delivery device
US7030097B1 (en) * 1999-07-14 2006-04-18 Cornell Research Foundation, Inc. Controlled nucleic acid delivery systems
WO2003039620A2 (en) * 2001-05-17 2003-05-15 Transpharma Medical Ltd. Integrated transdermal drug delivery system
CA2478822C (en) * 2002-03-11 2016-07-12 Altea Therapeutics Corporation Transdermal drug delivery patch system, method of making same and method of using same
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
US8116860B2 (en) 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
EP1499255B1 (de) * 2002-04-19 2015-07-22 Syneron Medical Ltd. In der hand gehaltene transdermale arzneimittelabgabe und analytenextraktion
US8133505B2 (en) * 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
US7662404B2 (en) * 2002-10-31 2010-02-16 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides
US7383084B2 (en) * 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
IL152574A (en) 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
US6745071B1 (en) * 2003-02-21 2004-06-01 Birch Point Medical, Inc. Iontophoretic drug delivery system
US11439815B2 (en) 2003-03-10 2022-09-13 Impulse Dynamics Nv Protein activity modification
US7840262B2 (en) 2003-03-10 2010-11-23 Impulse Dynamics Nv Apparatus and method for delivering electrical signals to modify gene expression in cardiac tissue
US8792985B2 (en) 2003-07-21 2014-07-29 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
US11779768B2 (en) 2004-03-10 2023-10-10 Impulse Dynamics Nv Protein activity modification
ES2650188T3 (es) * 2004-06-10 2018-01-17 3M Innovative Properties Company Dispositivo y kit de aplicación de parches
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
CA2580329C (en) 2004-09-13 2015-01-06 Chrono Therapeutics Inc. Biosynchronous transdermal drug delivery
EP1827571B1 (de) 2004-12-09 2016-09-07 Impulse Dynamics NV Proteinaktivitätsmodifizierung
WO2006097934A2 (en) 2005-03-18 2006-09-21 Metacure Limited Pancreas lead
EP1898991B1 (de) 2005-05-04 2016-06-29 Impulse Dynamics NV Proteinaktivitätsmodifizierung
WO2006131931A2 (en) * 2005-06-10 2006-12-14 Transpharma Medical, Ltd. Patch for transdermal drug delivery
WO2008006219A1 (en) * 2006-07-13 2008-01-17 Cardiac Bio-Systems Inc. Bio-electrode possessing a hydrophilic skin-contacting layer and an electrolyte substance
ES2618838T3 (es) * 2007-01-22 2017-06-22 Nitto Denko Corporation Sistema transdérmico de formación de poros y sistema de parche
US20080234627A1 (en) * 2007-03-22 2008-09-25 Wanda Dent Pivotally engaged multiple part electrotransport drug delivery device
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
CA2724949A1 (en) 2007-06-27 2008-12-31 The General Hospital Corporation Method and apparatus for optical inhibition of photodynamic therapy
US20090043244A1 (en) * 2007-08-08 2009-02-12 Inan Omer T Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change
JP5466161B2 (ja) * 2007-10-09 2014-04-09 トランスファーマ メディカル リミテッド 磁気的なパッチ連結物
WO2009050718A2 (en) * 2007-10-17 2009-04-23 Transpharma Medical Ltd. Dissolution rate verification
US20100293807A1 (en) * 2007-10-29 2010-11-25 Transpharma Medical, Ltd. Vertical patch drying
MX2010006062A (es) 2007-12-05 2010-09-14 Syneron Medical Ltd Aplicador desechable de energia electromagnetica y metodo para su uso.
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US20090312689A1 (en) * 2008-06-05 2009-12-17 Alza Corporation Adjustable Current Electrotransport Fentanyl Delivery Device
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
CA2817824A1 (en) 2010-11-23 2012-05-31 Nupathe, Inc. User-activated self-contained co-packaged iontophoretic drug delivery system
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8301238B2 (en) 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
AU2016211330A1 (en) 2015-01-28 2017-08-03 Chrono Therapeutics Inc. Drug delivery methods and systems
JP2018511127A (ja) 2015-03-12 2018-04-19 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 渇望入力及び支援システム
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 経皮薬剤送達の装置及び方法
US11642048B2 (en) 2018-05-04 2023-05-09 Dexcom, Inc. Systems and methods relating to an analyte sensor system having a battery located within a disposable base
AU2019279884A1 (en) 2018-05-29 2020-12-10 Morningside Venture Investments Limited Drug delivery methods and systems

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
US5135479A (en) * 1983-08-18 1992-08-04 Drug Delivery Systems, Inc. Programmable control and mounting system for transdermal drug applicator
US4883457A (en) * 1983-08-18 1989-11-28 Drug Delivery Systems Inc. Disposable and/or replenishable transdermal drug applicators and methods of manufacturing same
US4627429A (en) * 1986-02-28 1986-12-09 American Home Products Corporation Storage-stable transdermal adhesive patch
AU597890B2 (en) * 1986-03-14 1990-06-14 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US5250022A (en) * 1990-09-25 1993-10-05 Rutgers, The State University Of New Jersey Iontotherapeutic devices, reservoir electrode devices therefore, process and unit dose
US4725263A (en) * 1986-07-31 1988-02-16 Medtronic, Inc. Programmable constant current source transdermal drug delivery system
US4865582A (en) * 1987-06-05 1989-09-12 Drug Delivery Systems Inc. Disposable transdermal drug applicators
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
IL86076A (en) * 1988-04-14 1992-12-01 Inventor S Funding Corp Ltd Transdermal drug delivery device
DE3903794A1 (de) * 1989-02-09 1990-08-16 Lohmann Therapie Syst Lts Therapeutisches system zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung
US5320597A (en) * 1991-02-08 1994-06-14 Becton, Dickinson And Company Device and method for renewing electrodes during iontophoresis
WO1991015261A1 (en) * 1990-03-30 1991-10-17 Medtronic, Inc. Activity controlled electrotransport drug delivery device
US5037381A (en) * 1990-07-27 1991-08-06 Bock C Randolph Electrically assisted transdermal transport device and method for renewing the device

Also Published As

Publication number Publication date
WO1994027671A1 (en) 1994-12-08
DE69401938T2 (de) 1997-10-09
EP0700309A1 (de) 1996-03-13
AU7048494A (en) 1994-12-20
EP0700309B1 (de) 1997-03-05
JPH09500292A (ja) 1997-01-14
ATE149363T1 (de) 1997-03-15
JP3504269B2 (ja) 2004-03-08
US5445609A (en) 1995-08-29

Similar Documents

Publication Publication Date Title
DE69401938T2 (de) Vorrichtung bei elektroübertragungslieferung von wirkstoff
UA39172C2 (uk) Похідні 2-(2,6-дигалофеніламіно) фенілоцтової кислоти і спосіб їх одержання
DK230188D0 (da) Grundlag for slimhinde- og proteseklaebepastaer samt fremstilling og anvendelse heraf
AU577369B2 (en) Cross-bar quadrupole source
ES2190447T3 (es) Pañal desechable.
FI944852A (fi) Laite ja menetelmä lääketieteellisen instrumentin kiinnipitämiseksi
AU4886993A (en) Apparatus and method for locating a target on a portion of the anatomy
AR243365A1 (es) Placa presionadora para la union de los extremos de huesos fracturados.
DE3673441D1 (de) Vorrichtung fuer direkten antrieb von raedern.
NO864556L (no) Fremgangsmaate ved fremstilling av insulinpreparat.
CA2147874A1 (en) Adhesively secured pump fastener system
AU8595391A (en) Bis- and tris(trifluoromethyl)arylpyrrole insecticidal and acaricidal agents
DK476688A (da) Hiv-proteiner og -peptider, der er nyttige ved aids-diagnose, -profylakse og -terapi
EP0190755A3 (en) An n-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds
GB2143919A (en) Adhesively securable fastener
AU619978B2 (en) Watch comprising means for lateral postioning of the movement in the watch case
AU6697886A (en) Procedure and means for directing the power of A.D.C. voltage source
DK597886D0 (da) Fremgangsmaade til paafaering af tryk paa laedersubstrater
AU583132B2 (en) Method for the operation of an electrostatic filter
AU7116881A (en) 4-(n-(substituted-benzylidene)aminomethyl)cyclohexane-1- carboxylic acids
GR862285B (en) Pharmaceutical compositions for treating the high blood pressure
ATE66812T1 (de) Arzneimittel zur heilung von arteriosklerose, enthaltend ein pyrimido(2,1-b)benzothiazolderivat.
AU8199182A (en) N-substituted aminomethylphosphonic acids and esters thereof
GB8917028D0 (en) Component assembling machine,driving device therefor,and method of assembling
DE59001060D1 (de) Verfahren zum herstellen und verschliessen von klein- und kleinstsicherungen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition